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The Efficacy and Safety of Dinoprostone Vaginal Insert for Labor Induction Following Optimization of Standard Operating Procedure: A Retrospective Study in China

作     者:Ping Jin Bao-Min Yin 

作者机构:Department of ObstetricsZhuhai Center for Maternal and Child Health CareZhuhai 519000China 

出 版 物:《Journal of Clinical and Nursing Research》 (临床护理研究(英文))

年 卷 期:2023年第7卷第4期

页      面:110-119页

学科分类:1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

基  金:Ferring Pharmaceuticals 

主  题:Dinoprostone vaginal insert Induction of labor Standard operating procedure Vaginal delivery 

摘      要:Background:The study aimed to assess the efficacy and safety of dinoprostone vaginal insert in labor induction following optimization of standard operating procedure(SOP)and to discover independent predictors of vaginal ***:This study comprised 551 pregnant women who required cervical ripening with dinoprostone before induction of *** univariate and multivariate analyses,independent predictors of vaginal delivery were ***:443 of the 551 women(80.4%)gave birth *** delivery was predicted by maternal age(24-30 vs.24,P0.001;30-35 vs.24,P=0.03),gestational age(P=0.005),birth weight(P0.001),parity(P=0.001),pre-pregnancy BMI(P0.001),premature rupture of membranes(P=0.001),meconium-stained amniotic fluid(P0.001),fundal height(P0.001)and the Bishop score(P0.001).None of the women exhibited severe postpartum ***:The maternal age,gestational age,birth weight,parity,body mass index,premature membrane rupture,amniotic fluid contamination,fundal height,and the Bishop score were independent predictors of vaginal *** may guide the clinical use of dinoprostone for induction of labor.

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