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Online Scheduling on Two Parallel Identical Machines Under a Grade of Service Provision

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Journal of the Operations Research Society of China 2022年第4期10卷 689-702页

作者： Shuang Cai Ke Liu Data Department Beijing Kingsoft Cloud Network Technology Co.Ltd.Beijing100086China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100190China

In this paper,we investigate online scheduling problems on two parallel identical machines under a grade of service provision with makespan as the objective function.The jobs arrive over time and each job can be scheduled only when it has already been arrived.We consider three different versions:(i)the two machines cannot be idle at the same time until all arrived jobs have been processed;(ii)further to the first problem,jobs are processed on a first-come,first-serviced basis;(iii)each job must be assigned to one of the two machines as soon as it arrives.Respectively for three online scheduling problems,optimal online algorithms are proposed with competitive ratio(√5+1)/2,(√5+1)/2 and 5/3.

关键词： Online scheduling Parallel machines A grade of service provision gos

A Reliable Neighbor-Based Method for Identifying Essential Proteins by Integrating Gene Expressions, Orthology,and Subcellular Localization Information

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Tsinghua Science and Technology 2016年第6期21卷 668-677页

作者： Min Li Zhibei Niu Xiaopei Chen Ping Zhong Fangxiang Wu Yi Pan the School of Information Science and Engineering Central South University the Department of Mechanical Engineering and Division of Biomedical Engineering University of Saskatchewan the Department of Computer Science Georgia State University

Essential proteins are those necessary for the survival or reproduction of species and discovering such essential proteins is fundamental for understanding the minimal requirements for cellular life, which is also meaningful to the disease study and drug design. With the development of high-throughput techniques, a large number of Protein-Protein Interactions（PPIs） can be used to identify essential proteins at the network level. Up to now, though a series of network-based computational methods have been proposed, it is still a challenge to improve the prediction precision as the high false positives in PPI networks. In this paper, we propose a new method gos to identify essential proteins by integrating the Gene expressions, Orthology, and Subcellular localization information.The gene expressions and subcellular localization information are used to determine whether a neighbor in the PPI network is reliable. Only reliable neighbors are considered when we analyze the topological characteristics of a protein in a PPI network. We also analyze the orthologous attributes of each protein to reflect its conservative features, and use a random walk model to integrate a protein＇s topological characteristics and its orthology. The experimental results on the yeast PPI network show that the proposed method gos outperforms the ten existing methods DC, BC, CC, SC, EC, IC, NC, Pe C, ION, and CSC.

关键词： essential protein reliable neighbors gos orthology subcellular localization information

A real-time tunable arbitrary power ratios graphene based power divider

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Science China(Information Sciences) 2018年第8期61卷 104-106页

作者： Haowen SHU Yuansheng TAO Ming JIN Xingjun WANG Zhiping ZHOU State Key Laboratory of Advanced Optical Communications System and Networks School of Electronics Engineering and Computer Science Peking University

Dear editor,Recently,photonics integrated circuits have attracted extensive consideration for its realization of large-scale integration of various devices and functionalities on a single chip[1].As a fundamental buil... 详细信息

关键词： Figure A real-time tunable arbitrary power ratios graphene based power divider length gos

Delay Testing Viability of Gate Oxide Short Defects

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Journal of Computer Science & Technology 2005年第2期20卷 195-200页

作者： J.M.Gallière M.Renovell F.Azais Y.Bertrand Laboratoired＇InformatiqueRobotiqueMicroèlectroniquedeMontpellierLIRMM-UMII UniversitddeMontpellierH：SciencesetTechniquesduLanguedocUMRC5506CNRS-161rueAda34392MontpellierCedex5France

Gate Oxide Short (gos) defects are becoming predominant as technology is scaling down. Boolean and IDDQ testing of this defect has been widely studied but there is no paper dedicated to delay testing of this defect. So, this paper studies the delay behavior of Gate Oxide Short faults due to pinhole in the gate oxide. The objective of this paper is to give a detailed analysis of the behavior of the gos defect taking into account the random parameter of the defect such as the gos resistance and the gos location. Because an accurate analysis is desired, the bi-dimensional array will be used.Because a complete analysis is desired, we derive the dynamic characteristic of the gos as a function of the gos resistance and location. It is demonstrated that i) gos has a significant impact on gate delay, ii) gos located close to the source of the transistor and with small resistance has very high impact.

关键词： VLSI 延迟测试 gos 集成电路

Evaluating the prognosis and degree of brain injury by combined S-100 protein and neuron specific enolase determination

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Neural Regeneration Research 2006年第7期1卷 649-652页

作者： Xihua Wang Xinding Zhang Department of Neurosurgery Second affiliated HospitalLanzhou UniversityLanzhou 730030Gansu ProvinceChina Department of NeurosurgerySecond affiliated HospitalLanzhou UniversityLanzhou 730030Gansu ProvinceChina

BACKGROUND: S-100 and neuron specific enolase (NSE) possess the characteristics of specific distribution in brain and relative stable content. Some studies suggest that combined detection of the both is of very importance for evaluating the degree of brain injury. OBJECTIVE: To observe the changes of S-100 protein and NSE levels at different time points after acute brain injury, and evaluate the values of combined detection of the both for different injury degrees, pathological changes and prognosis. DESIGN: Case-control observation. SETTING: Department of Neurosurgery, Second Affiliated Hospital, Lanzhou University. PARTICIPANTS: Thirty-four inpatients with brain injury, 19 males and 15 females, aged 15 to 73 years, who received treatment between September 2005 and May 2006 in the Department of Neurosurgery, Second Affiliated Hospital, Lanzhou University, were recruited. The patients were admitted to hospital at 24 hours after brain injury. After admission, skull CT confirmed that they suffered from brain injury. Following Glasgow coma score (GCS) on admission, the patients were assigned into 3 groups: severe group (GCS 3 to 8 points, n =15), moderate group (GCS 9 to 12 points, n =8) and mild group (GCS 13 to 15 points, n =11). Following Glasgow outcome scale (gos) at 3 months after brain injury, the patients were assigned into good outcome group (gos 4 to 5 points, good recovery and moderate disability included, n =19) and poor outcome group (gos 1 to 3 points, severe disability, vegetative state and death, n =15). Ten subjects who received health examination concurrently were chosen as normal control group , including 6 males and 4 females , aged (45.4±14.3)汤(c)years. In our laboratory, the normal level of NSE was ≤15.2 ng/L, and that of S100 was ≤0.105μg/L. METHODS: ①Blood samples of control group were collected when the subjects received health examination. Blood samples of patients with brain injury were collected at 24 hours, 3, 7 and 14 days after injury. According to the instructions of NSE and S-100 kit

关键词： NSE gos GCS

比较CT立体定位引导穿刺清除术和常规穿刺清除术对脑出血患者内皮素表达水平、gos评分、SF-36评分及颅内感染发生率影响

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辽宁医学杂志 2023年第6期37卷 80-84页

作者：祁贝贝姜田利李文慧郑州市第七人民医院河南郑州450000

目的探究比较CT立体定位引导穿刺清除术和常规穿刺清除术对脑出血患者内皮素表达水平、gos评分、SF-36评分及颅内感染发生率影响。方法选取我院2019年5月~2021年5月脑病科收治的178例脑出血患者为研究对象,采用随机分组法分为观察组与... 详细信息

目的探究比较CT立体定位引导穿刺清除术和常规穿刺清除术对脑出血患者内皮素表达水平、gos评分、SF-36评分及颅内感染发生率影响。方法选取我院2019年5月~2021年5月脑病科收治的178例脑出血患者为研究对象,采用随机分组法分为观察组与对照组,两组各89例。对照组采用常规穿刺清除术,观察组采用CT立体定位引导穿刺清除术。观察两组患者治疗前后血清内皮功能情况、gos评分、NIHSS评分及SF-36评分。观察两组患者手术一般情况与不良反应发生率。结果两组患者术前NO、ET-1水平无统计学差异(P>0.05)。术后两组患者NO水平无统计学差异(P>0.05),但术后观察组ET-1水平较对照组显著降低(P0.05)。治疗后观察组生理功能、社会功能、角色限制、活力、情感职能、精神健康、身体疼痛、总体健康评分显著高于对照组(P<0.05)。观察组穿刺时间、穿刺成功所用次数、引流管脑室走行长度及引流时间均显著低于对照组(P<0.05)。观察组总不良反应发生率为3.36%略低于对照组5.60%,但两组患者总不良反应发生率无统计学差异(χ^(2)=0.523,P=0.469)。结论CT立体定位引导穿刺清除术较常规穿刺清除术操作简便,能有效降低患者内皮素水平、提高患者生活质量,降低神经功能损伤。

关键词： CT立体定位引导穿刺清除术常规穿刺清除术脑出血内皮素 SF-36 gos

不同长期降压方案对急性高血压脑出血预后的影响

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临床神经外科杂志 2022年第5期19卷 543-548页

作者：谢柯王亮凌伟华杨鹏徐峰陈雄辉苏州大学附属第一医院急诊外科苏州215000

目的观察不同长期降压方案对急性高血压脑出血预后及炎性因子水平的影响。方法回顾性分析苏州大学附属第一医院于2020年1月—2021年8月收治的118例急性高血压脑出血患者的临床资料,根据患者发病前是否患有高血压及所使用的降压药物种... 详细信息

目的观察不同长期降压方案对急性高血压脑出血预后及炎性因子水平的影响。方法回顾性分析苏州大学附属第一医院于2020年1月—2021年8月收治的118例急性高血压脑出血患者的临床资料,根据患者发病前是否患有高血压及所使用的降压药物种类,将118例患者分为1组(30例,发病前未患有高血压)、2组(27例,发病前已临床诊断高血压且规范服用血管紧张素转换酶抑制剂即ACEI/ARB类降压药)、3组(31例,发病前已临床诊断高血压且规范服用钙通道阻滞剂即CCB类降压药)和4组(30例,发病前已临床诊断高血压但未治疗),其中每位患者都在发病72 h内入院,并经标准化治疗,对比四组患者入院后GCS评分、基础血压、出血部位、出血量、基础状态、炎性因子水平及出院3个月后随访的gos评分。结果四组患者入院GCS评分、出血部位、出血量、糖尿病史、脑梗死、脑出血史、阿司匹林服用史、冠心病史、房颤史、中性粒细胞/淋巴细胞基线资料的差异均无统计学意义(P>0.05),gos评分、基础收缩压、基础舒张压基线资料的差异具有统计学意义(P 0.05),2组和3组、3组和4组之间两两比较,差异具有统计学意义(P gos无显著性差异(P=0.794>0.050),2组与3组的gos有显著性差异(P=0.004 gos有显著性差异(P=0.022 0.050)、舒张压(P=0.359>0.050)无显著性差异,出血量有显著性差异(P=0.000 <0.050)。结论相较于长期服用ACEI/ARB类药物,长期服用CCB类药物的急性高血压脑出血患者结局预后更好。

关键词：急性高血压脑出血炎性因子 GCS gos

亚低温对重型脑损伤患者继发性脑损伤的作用评价

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中华急诊医学杂志 2017年第12期26卷 1375-1378页

作者：熊伟川曹小宏李新明万建国南昌大学第三附属医院急危重症医学部南昌330008 南昌大学第三附属医院影像科南昌330008 南昌大学第三附属医院神经内科南昌330008

目的评估亚低温联合高压氧（hyperbaricoxygen，HBO）对重型颅脑损伤患者继发性脑损害的影响。方法本次临床试验研究为前瞻性研究，将伤后8h内入院的重型颅脑损伤患者42例，采用随机数字表法分为亚低温联合HBO的治疗组和常规HBO治疗的... 详细信息

目的评估亚低温联合高压氧（hyperbaricoxygen，HBO）对重型颅脑损伤患者继发性脑损害的影响。方法本次临床试验研究为前瞻性研究，将伤后8h内入院的重型颅脑损伤患者42例，采用随机数字表法分为亚低温联合HBO的治疗组和常规HBO治疗的对照组各2l例。分别于伤后第1天、15天、30天复查头颅cT，计算脑出血量及脑水肿体积；同时进行GCS（GlasgowComaScale）评分；统计两组患者出现脑梗死的例数；伤后半年，对两组患者进行gos（GlasgowOutcomeScore）预后评分。采用SPSS13．0统计软件，两组样本率的比较采用连续性校正的X。检验，用独立样本t检验进行组间两两比较，以P〈0．05为差异具有统计学意义。结果（1）治疗组伤后15d和30d的脑出血量和水肿体积明显小于对照组[（21．71±4．3）vs．（26．33±5．23）；（14．33±1．93）vs．（16．86±2．86），P〈0．05]；（2）伤后15d和30d治疗组GCS评分高于对照组[（4．62±0．49）vs．（4．29±0．56）；（9．76±1．37）vs．（8．57±0．92），P〈0．05]；（3）治疗组出现外伤性脑梗死2例数，而对照组9例（χ2=4．434，P=0．035）；伤后6个月，治疗组gos评分高于对照组[（4．29±0．84）vs．（3．38±0．74），P=0．001]。结论亚低温联合高压氧治疗能够减轻重型颅脑损伤的继发性脑损伤和改善患者预后，值得临床上进一步探讨，亚低温的作用机制有待于进一步研究。

关键词：亚低温高压氧重型颅脑损伤继发性脑损伤体温管理脑梗死 GCS gos

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幕上高血压性脑出血个体化治疗的疗效观察

中文科技期刊数据库（全文版）医药卫生 2023年第11期 52-54页

作者：杜延平无锡市中医医院江苏无锡214071

观察幕上高血压性脑出血个体化治疗的疗效。方法选取我院2018.02-2020.02收治的60例幕上高血压性脑出血患者进行回顾分析,为其开展个体化治疗,根据治疗方式,分为甲、乙、丙、丁四组,治疗方式包括保守治疗、穿刺引流术、神经内镜术、开... 详细信息

观察幕上高血压性脑出血个体化治疗的疗效。方法选取我院2018.02-2020.02收治的60例幕上高血压性脑出血患者进行回顾分析,为其开展个体化治疗,根据治疗方式,分为甲、乙、丙、丁四组,治疗方式包括保守治疗、穿刺引流术、神经内镜术、开颅+去骨瓣减压术。其中甲组(保守治疗)9例,乙组(穿刺引流)25例,丙组(神经内镜)14例,丁组(开颅+去骨瓣减压术)12例。回顾、分析各组患者的治疗与预后效果。结果分析可知,甲、乙、丙、丁四组gos评分优良率分别为100.00%、92.00%、71.43%、58.33%,病死率分别为0.00%、0.00%、7.14%、8.33%。结论在对幕上高血压性脑血压患者进行治疗时,根据患者的具体情况,采取个体化治疗方案,能够对患者存活率的予以有效保障,最大程度挽救患者的生命,优化其预后质量。

关键词：幕上高血压性脑出血神经内镜手术保守治疗 gos