BACKGROUND Several studies found that early pancreatic atrophy detected by computed tomo-graphy(CT)within 6 months was associated with a high incidence of diabetes in patients with type-1 autoimmune pancreatitis(AIP)r...
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BACKGROUND Several studies found that early pancreatic atrophy detected by computed tomo-graphy(CT)within 6 months was associated with a high incidence of diabetes in patients with type-1 autoimmune pancreatitis(AIP)receiving steroid therapy;however,no long-term follow-up studies have been *** To investigate pancreatic volume(PV)changes using three dimensional(3D)-CT volumetry and their relationship with IgG4 and diabetes in patients with *** This retrospective study included 33 patients with type-1 AIP receiving steroid *** were divided into diffuse(D-type)and mass-forming type(M-type)*** was determined by semi-automated 3D-CT volumetry,and changes between initial and follow-up values were *** relationship between PV and serum IgG4 levels was analyzed by Spearman’s rank *** PV atrophy ratio compared with the presumed normal PV at the time of last follow-up CT and its relationship with diabetes were *** There were 16 D-type and 17 M-type patients with long-term follow-up(mean,95.8 months).The regression curve of mean relative PV change reduced exponentially and rapidly during the first 25 months and then more slowly in both *** overall cumulative pancreas re-enlargement rates at 1,3,5,7 and 10 years were 6.1%,12.2%,29.2%,47.5%and 55.0%,*** was a moderate-to-very strong positive correlation(ρ≥0.4)between PV and serum IgG4 levels in nine(9/13,69.2%)*** 33 patients showed pancreatic atrophy(mean 59.3%)after long-term *** with D-type AIP had a significantly higher atrophy rate and higher incidence of diabetes than M-type patients(Pfollow-up.
Objective To explore the remote efficacy and safety of consciousness-restoring resuscitation (Xingnao Kaiqiao, short for XNKQ) acupuncture on cerebral infarction at recovery phase. Methods Two hundred and thirty-fou...
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Objective To explore the remote efficacy and safety of consciousness-restoring resuscitation (Xingnao Kaiqiao, short for XNKQ) acupuncture on cerebral infarction at recovery phase. Methods Two hundred and thirty-four cases of cerebral infarction at recovery phase were randomized into XNKQ group and routine acupuncture group (routine group) in light of SAS code. One hundred and sixteen cases in the XNKQ group were treated with XNKQ acupuncture (once a day, totally 4 weeks) and routine treatment with western medicine. One hundred and eighteen cases in the routine group received routine acupuncture and routine treatment with western medicine. follow-up lasted 6 months. Primary indexes: the situations of survival, treatment and recurrence at the end of follow-up. Secondary indexes: assessment of nerve functions at the end of follow-up and rate of adverse events during acupunc- ture. Results In 6 months follow-up, the mortality was 0.86% and rate of continuous treatment was 36.21% in the XNKQ group and they were 1.69% and 36.44% respectively in the routine group. The differences did not present statistical significance between the two groups (X^2 = 0.29, P=0.59; X^2 = 0.32, P = 0.57). Concerning to the decrease of recurrence rate and improvement of nerve functions, the out-comes in the XNKQ group were superior to those in the routine group (P〈0.01). Severe adverse events did not happen in the two groups. Conclusion XNKQ acupuncture is safe therapy and its remote efficacy is superior to that of routine acupuncture in the decrease of recurrence rate and improvement of nerve functions.
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