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Correlation between ductus venosus spectrum and right ventricular diastolic function in isolated single-umbilical-artery foetus and normal foetus in third trimester

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World Journal of Clinical Cases 2020年第23期8卷 5866-5875页

作者： Tian-Gang Li Fang Nie Xiao-Yan Xu Department of Ultrasound Diagnosis Gansu Provincial Maternity and Child-Care HospitalLanzhou 730050Gansu ProvinceChina Department of Ultrasound Diagnosis Lanzhou University Second HospitalLanzhou 733000Gansu ProvinceChina

BACKGROUND Single umbilical artery(SUA)is the most common umbilical cord malformation in prenatal *** presence of an SUA can cause blood circulation disorder in the foetus and functional changes of the foetal heart,affecting foetal *** right ventricular diastolic functions in foetuses with isolated SUA and in normal foetuses in the third trimester were evaluated using the spectral Doppler of blood flow in the foetal ductus venosus(DV).AIM To evaluate the right ventricular diastolic functions in foetuses with isolated SUA and in normal foetuses in the third *** Colour Doppler was used to measure the spectrum of foetal DV and tricuspid orifice in 34 foetuses with isolated SUA aged 28-39 wk and in age-matched healthy *** DV flow velocities and velocity ratios were *** early passive/late active(E/A)ratio at the tricuspid orifice and tissue Doppler Tei index of the foetal right ventricular in the two groups were also *** During the third trimester,the isolated SUA group showed a lower‘a’-wave peak velocity in the DV than the control group(P<0.05).The correlations between the velocity ratios and E/A ratio at the tricuspid orifice in the two groups were analysed,and the correlation between the ventricular late diastolic velocity/ventricular diastolic peak flow velocity and E/A ratios was the best(R^2of the isolated SUA group:0.520;R2 of the control group:0.358).The correlations between the velocity ratios and tissue Doppler Tei index of foetal right ventricular in the two groups were analysed,and the correlation between the pulsatility index for veins(PIV)and tissue Doppler Tei index ratios was the best(R2 of the isolated SUA group:0.865;R2 of the control group:0.627).CONCLUSION In the isolated SUA group,the atrial systolic peak velocity‘a’decreased,and this finding might be related to the changes in foetal cardiac *** ratio of ventricular late diastolic velocity to ventricular diastolic peak flow

关键词： Isolated single umbilical artery Ductus venosus Velocity Right ventricular diastolic function foetus

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Effects of Biological Materials and Collection Media on PCR Detection of <i>Tritrichomonas foetus</i>

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Open Journal of Animal Sciences 2019年第1期9卷 121-128页

作者： Kristin A. Clothier Bret Mc Nabb Andrea Torain Steve Reinl Jeff Ondrak California Animal Health and Food Safety Laboratory System Davis CA USA Department of Population Health and Reproduction School of Veterinary Medicine University of California Davis Davis CA USA Great Plains Veterinary Educational Center University of Nebraska-Lincoln Clay Center NE USA

Tritrichomonas foetus is an important pathogen of the bovine reproductive tract causing early embryonic death and abortion in cows and persistent, asymptomatic infection in bulls. PCR detection methods have greatly enhanced diagnostic accuracy over culture;however, pre-analytical sample handling is just as critical as technical performance in detecting this pathogen and is not well studied. The purpose of this study was to investigate the effects of biological materials present in the prepuce on PCR detection of T. foetus in a variety of collection media. Simulated preputial samples were created using InPouchTM (IP) media, lactated ringers solution (LRS), or sterile saline (SAL);inoculated with low numbers of one of three T. foetus strains;and spiked with either blood, semen, urine, or sham treatment. Samples were transported to the lab, placed in growth media (LRS and SAL samples), incubated, and tested for T. foetus by PCR. Samples containing urine had statistically significantly greater mean Ct values (P = 0.008) than samples containing other materials, seen most dramatically in IP (P foetus. Overall, SAL collections also had significantly higher mean Ct than IP or LRS (P foetus PCR detection. The presence of urine in preputial samples can result in false negative results, while blood had no detrimental effects.

关键词： Tritrichomonas foetus PCR Detection Urine Semen Blood

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Basic biological aspects of Tritrichomonas foetus of re-levance to the treatment of bovines suffering of tricho-moniasis

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Open Journal of Animal Sciences 2011年第3期1卷 112-120页

作者： Newton Soares da Silva Susane Moreira Machado Fernando Costa e Silva Filho Cristina Pacheco-Soares Laboratório de Biologia Celular e Tecidual Instituto de Pesquisa e Desenvolvimento Universidade do Vale do Paraíba São José dos Campos Laboratório de Dinâmica dos Compartimentos Celulares Instituto de Pesquisa e Desenvolvimento Universidade do Vale

Tritrichomonas foetus is a flagellate protozoan and the etiological agent of bovine genital tri-chomoniasis [1], which is an infectious vene- real disease. This parasite is usually found as- sociated with the mucosal surface of the uro- genital tract in females or the male preputial and penile membranes. In females, the clinical ma-nifestations may include abortion, with repe- tition of estrus at irregular intervals, vaginitis, cervicitis, endometritis, and pyometra. Parasi- tized males may have a discharge with small nodules in the preputial membrane. After that, the bulls have no clinical symptoms, and are thus an asymptomatic carrier that may spread the infection. Considering that a bull could cover up to twenty females [2], bovine genital trichomoniasis is a serious medical and veteri- nary problem, with economical repercussion for beef and milk production. As T. foetus is an amitochondrial and aerotolerant organism, en- ergy production under low O2 tension in the protozoan is done via hydrogenosome, which, as the name suggests, is the organelle where H2 is generated [3,4,5]. The molecular machinery of mitochondrial cell death is, therefore, absent in this parasite and the mechanism that activates of cell death program is not clear. This review seeks to understand the characteristics of the protozoan parasite T. foetus in order to propose new therapies for animals suffering from this infectious and contagious agent.

关键词： Reproduction Protozoan Parasite Tritrichomonas foetus

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Delivery Complications of the Single Fat Large foetus (Macrosomia) with Teenagers at the Obstetrics and Gynaecology Department of the Donka National Hospital, University Teaching Hospital (CHU) of Conakry, Guinea

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Open Journal of Obstetrics and Gynecology 2019年第5期9卷 624-630页

作者： Boubacar Siddi Diallo Mamadou Hady Diallo Ousmane Balde Ibrahima Sylla Ibrahima Conte Abdourahmane Diallo Oumou Hawa Bah Mouctar Sylla Ibrahima Sory Balde Telly Sy Namory Keita University Department of Gynecology-Obstetrics Donka National HospitalConakryGuinea University Department of Gynecology-Obstetrics Ignace Deen National HospitalConakryGuinea

Objectives: The objectives of this work were to: 1) Calculate the delivery frequency of the large foetus with complications to teenagers;2) Describe the epidemiological profile of these teenagers;3) Identify the risk factors of the large foetus and to establish the maternal prognosis and foetus. Methodology: This was a prospective descriptive 6-month study performed at the Obstetrics and Gynaecology Department of the Donka National Hospital, CHU of Conakry, Guinea. We chose a regular amplitude of one year and we got the following slices: 16 years, 17 years, 18 years. Results: We recorded 14.23% (801/5629) teenage deliveries of which 9.4% (75/801) deliveries are single fat fetus and 93.3% (70/75) of them developed complications. The epidemiological profile was that of an 18 years old teenager (61.4%), single (58.6%), professional (44.3%), out of school (57.1%), primiparous (68.6%), having performed 3 - 4 CPN (47.1%), coming from home (65.7%) and carrying a full term pregnancy (100%) and having delivered by high way medical assistance (52.9%). Risk factors were dominated by the male foetus (75.7%). Maternal morbidity was dominated by cervico-perineal tears 28.6%. The recorded maternal mortality was 4.3%. The 3 cases of maternal deaths were caused by the hemorrhage. The APGAR score at the first minute was in 51.4% between 4 and 6;at the 5th minute in 80% between 7 and 10. The most common foetal complication was acute foetal distress 44.3%. Foetal lethality was 12.8%. Conclusion: Here, we demonstrated the teenage pregnancy and macrosomia in this area. We did not show how we can improve this situation based on the data;however, describing this situation may be of use as a fundamental data to make a better antenatal checkup and teenager-education.

关键词： Teenager Large foetus Complications

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Cloned goats (Gapra hircus) from foetal fibroblast cell lines

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Chinese Science Bulletin 2000年第1期45卷 34-38页

作者： WANG Yuge ZOU Xiangang LIU Jie ZHANG Jingpu ZHANG Xuechen LAO Weide DU Miao CHENG Guoxing CHENG Yong CHEN Jianquan ZHANG Suolin XU Shaofu Institute of Developmental Biology Chinese Academy of SciencesBeijing 100080China College of Animal Sciences and Veterinary Yangzhou UniversityYangzhou 225001China The Babraham Institute Cambridge CB2 4ATUK

Mammalian cloning has been one of the most active research topics in the world. Cioning with in vitro culured foetal fibroblast cells, in comparison with embryonic cells, can be used not only to theoretically study the embryonic or cellular development and differentiation in mammals, but also to utilize the unlimited fibroblast cells to produce large numbers of clonings. The preliminary results are as follows: (i) The division and development of the cloned embryos with embryonic donor cells and goat foetal fibroblast donor cells were 55%, 77% and 35%, 31%, respectively. There is no significant statistical difference between them. (? These studies result in the birth of two cloned goats derived from two 30-day foetal fibroblast celi lines, which are the first cloned mammals from somatic cells in China. This project has established a technological data base for the furture research on adult mammalian somatic cloning and nucleocytoplasmic interactions in animal development, and a novel technique for the

关键词： goat (Gapra hircus) foetus fibroblast cloning total-potentiality.

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Excretion of biliary compounds during intrauterine life

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World Journal of Gastroenterology 2009年第7期15卷 817-828页

作者： Rocio IR Macias Jose JG Marin Maria A Serrano Laboratory of Experimental Hepatology and Drug Targeting CIBERehdUniversity of Salamanca

In adults,the hepatobiliary system,together with the kidney,constitute the main routes for the elimination of several endogenous and xenobiotic compounds into bile and urine,***,during intrauterine life the biliary route of excretion for cholephilic compounds,such as bile acids and biliary pigments,is very *** very early in pregnancy the fetal liver produces bile acids,bilirubin and biliverdin,these compounds cannot be efficiently eliminated by the fetal hepatobiliary system,owing to the immaturity of the excretory machinery in the fetal ***,the potentially harmful accumulation of cholephilic compounds in the fetus is prevented by their elimination across the *** to the presence of detoxifying enzymes and specifi c transport systems at different locations of the placental barrier,such as the endothe-lial cells of chorionic vessels and trophoblast cells,this organ plays an important role in the hepatobiliary-like function during intrauterine *** relevance of this excretory function in normal fetal physiology is evident in situations where high concentrations of biliary compounds are accumulated in the *** may result in oxidative stress and apoptosis,mainly in the placenta and fetal liver,which might affect normal fetal development and challenge the fate of the *** present article reviews current knowledge of the mechanisms underlying the hepatobiliary function of the fetal-placental unit and the repercussions of several pathological conditions on this tandem.

关键词： Bile acids Bilirubin foetus Liver Placenta

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Maxillofacial trauma in a pregnant patient:Contemporary management principles with a case report&review of literature

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Chinese Journal of Traumatology 2020年第2期23卷 78-83页

作者： Geetha Sridharan Elavenil Panneerselvam Keerthana Ponvel Swetha Tarun V.B.Krishna Kumar Raja Department of Oral and Maxillofacial Surgery SRM Dental College and HospitalRamapuram CampusRamapuramChennai 600089Tamil NaduIndia

Trauma during pregnancy deserves special attention because of its management objectives,***-being of both pregnant woman and *** trauma directly affects the nutrition of foetus by interfering with the normal functions in a pregnant woman such as mouth *** and breathing,Hence early restitution of form and function of maxillofacial skeleton is ***,the gravid status is associated with numerous anatomical and physiological changes which present with clinical dilemma related to imaging and treatment.A careful scrutiny of the patient's systermic and gestational status is absolutely essential before,during and after instituting any interventional *** present a case of bilateral condyle fracture in a 30-year-old pregnant woman in the third trimester(32 weeks).She was treated with inter maxillary fixation using orthodontic brackets&*** successful restitution of occlusion,the patient was advised aggressive physiotherapy which ensured normal mouth *** weeks later,the patient delivered *** patient was followed up at one month and 3 month and demonstrated restitution of normal occlusion,mouth opening and lower|acial *** article aims at analyzing the contermporary principles in management of maxillfacial trauma in a pregnant woman and clarifying the common misconceptions.

关键词： Trauma Pregnancy foetus Condyle fracture

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