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具有12.37%的光电转换效率及18.6%的平均可见光透过率的半透明聚合物太阳能电池

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Science Bulletin 2020年第2期65卷 131-137,88页

作者：胡拯豪王智安桥石张福俊 Key Laboratory of Luminescence and Optical Information Ministry of EducationBeijing Jiaotong UniversityBeijing 100044China School Electrical Engineering Beijing Jiaotong UniversityBeijing 100044China

本文制备了一系列以PM6为给体、窄带隙材料Y6为受体的聚合物太阳能电池,分别以100 nm铝或1 nm金/(20,15,10 nm)银作为电极来制备不透明及半透明器件.以不透明器件为基础,优化有源层的厚度,当有源层厚度为100 nm时,器件的光电转换效率达... 详细信息

本文制备了一系列以PM6为给体、窄带隙材料Y6为受体的聚合物太阳能电池,分别以100 nm铝或1 nm金/(20,15,10 nm)银作为电极来制备不透明及半透明器件.以不透明器件为基础,优化有源层的厚度,当有源层厚度为100 nm时,器件的光电转换效率达到了15.83%.100 nm厚的混合薄膜的平均可见光透过率为50.5%,这表明利用该有源层有望制备出高效率半透明聚合物太阳能电池.分别以1 nm金/20 nm银,1 nm金/15 nm银,1 nm金/10nm银复合电极代替铝电极(这种金/银复合电极在可见光范围内透过率较高,在近红外光范围透过率较低),所制备的半透明聚合物太阳能电池的光电转换效率和平均可见光透过率分别达到了14.20%和8.9%,13.32%和12.5%,12.37%和18.6%,这处于目前报道的半透明聚合物太阳能电池性能最高的行列.这一工作表明:开发高可见光透过率、低近红外光透过率电极以及使用窄带隙材料为有源层是制备高效率半透明聚合物太阳能电池的有效方法.

关键词： Semitransparent polymer solar cells Narrow band gap materials Semitransparent electrode Power conversion efficiency Average visible transmittance Photopic response of human Eye

Validating a tool to assess Eye health knowledge, attitude and practice in Cambodia and Vietnam

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International Journal of Ophthalmology(English edition) 2019年第11期12卷 1767-1774页

作者： Noela Prasad Gail M Ormsby Robert P Finger Institute for Health and Sport Victoria UniversityMelbourneVIC 3011Australia VACCHO CollingwoodVIC 3066Australia Professional Studies Faculty of BusinessEducationLaw and ArtsUniversity of Southern QueenslandWest StreetToowoombaQLD 4350Australia Lifestyle Research Centre Avondale College of Higher EducationCooranbongNSW 2265Australia Department of Ophthalmology University of BonnRegina-Pacis-Weg 3Bonn 53113Germany

AIM: To develop an Eye health knowledge, attitude and practice(EH-KAP) field-based assessment tool for use in implementing effective Eye health care services.METHODS: An instrument development and validation study. A Vietnam EH-KAP dataset were used to identify and eliminate redundant questions to develop a standardized tool. Face validity was assessed by the KAP survey team. Internal validity(congruency/criterion) was assessed by comparing descriptive analysis of two datasets(n=531;n=38) collected from the same sampling frame at different time points. Weighted scores were calculated for each construct. Kappa values for test-retest and inter-observer agreement were calculated to check the reliability of responses. The modified version was assessed by analysing the raw and ungrouped data. Responses were weighted and agreement was tested by comparing construct scores.RESULTS: Totally 38 respondents were included in this validation process(mean age 58.5 y). Mean scores for knowledge were 9.15(old questionnaire n=531) and 5.05(modified version). For attitude, the scores were 2.23 and 2.42, and for practice the scores were 3.33 and 2.21. Testretest agreement was between 62% to 93%(Kappa 0.24 to 0.86) for the ungrouped raw data, and 55% to 72%(Kappa 0.42 to 0.65) for KAP domain. Inter-observer Kappa value for ungrouped data was 0.37 and 0.45 for the weighted scores.CONCLUSION: This standardized tool applied at critical time points can assess trends in KAP within the same population and for comparison across groups. If used alongside a Rapid Assessment of Avoidable Blindness(RAAB), this tool provides a comprehensive perspective on Eye-health of a population.

关键词： validation knowledge attitude practice Eye health knowledge,attitude and practice questionnaire

Synchronization between frontal Eye field and area V4 during free-gaze visual search

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Zoological Research 2019年第5期40卷 394-403页

作者： Ting Yan Hui-Hui Zhou Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences

Information flow between the prefrontal and visual cortices is critical for visual behaviors such as visual search. To investigate its mechanisms, we simultaneously recorded spike and local field potential (LFP) signals in the frontal Eye field (FEF) and area V4 while monkeys performed a free-gaze visual search task. During free-gaze search, spike-LFP coherence between FEF and V4 was enhanced in the theta rhythm (4–8 Hz) but suppressed in the alpha rhythm (8–13 Hz). Cross-frequency couplings during the Cue period before the search phase were related to monkey performance, with higher FEF theta-V4 gamma coupling and lower FEF alpha-V4 gamma coupling associated with faster search. Finally, feature-based attention during search enhanced spike-LFP coherence between FEF and V4 in the gamma and beta rhythms, whereas overt spatial attention reduced coherence at frequencies up to 30 Hz. These results suggest that oscillatory coupling may play an important role in mediating interactions between the prefrontal and visual cortices during visual search.

关键词： Synchronization Frontal Eye field (FEF) V4 Visual search

Accurate and Robust Eye Center Localization via Fully Convolutional Networks

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IEEE/CAA Journal of Automatica Sinica 2019年第5期6卷 1127-1138页

作者： Yifan Xia Hui Yu Fei-Yue Wang the School of Creative Technologies University of PortsmouthPortsmouthPO1 2DJUK the State Key Laboratory of Management and Control for Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China

Eye center localization is one of the most crucial and basic requirements for some human-computer interaction applications such as Eye gaze estimation and Eye tracking. There is a large body of works on this topic in recent years, but the accuracy still needs to be improved due to challenges in appearance such as the high variability of shapes, lighting conditions, viewing angles and possible occlusions. To address these problems and limitations, we propose a novel approach in this paper for the Eye center localization with a fully convolutional network(FCN),which is an end-to-end and pixels-to-pixels network and can locate the Eye center accurately. The key idea is to apply the FCN from the object semantic segmentation task to the Eye center localization task since the problem of Eye center localization can be regarded as a special semantic segmentation problem. We adapt contemporary FCN into a shallow structure with a large kernel convolutional block and transfer their performance from semantic segmentation to the Eye center localization task by fine-tuning.Extensive experiments show that the proposed method outperforms the state-of-the-art methods in both accuracy and reliability of Eye center localization. The proposed method has achieved a large performance improvement on the most challenging database and it thus provides a promising solution to some challenging applications.

关键词： Deep learning Eye center localization Eye gaze estimation Eye tracking fully convolutional network (FCN) humancomputer interaction

Assessing gray matter volume in patients with idiopathic rapid Eye movement sleep behavior disorder

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Neural Regeneration Research 2019年第5期14卷 868-875页

作者： Xian-Hua Han Xiu-Ming Li Wei-Jun Tang Huan Yu Ping Wu Jing-Jie Ge Jian Wang Chuan-Tao Zuo Kuang-Yu Shi PET Center Huashan Hospital Fudan University Department of Radiology Huashan Hospital Fudan University Department of Neurology Huashan Hospital Fudan University Department of Nuclear Medicine Technical University Munich

Idiopathic rapid Eye movement sleep behavior disorder(iRBD) is often a precursor to neurodegenerative disease. However, voxel-based morphological studies evaluating structural abnormalities in the brains of iRBD patients are relatively rare. This study aimed to explore cerebral structural alterations using magnetic resonance imaging and to determine their association with clinical parameters in iRBD patients. Brain structural T1-weighted MRI scans were acquired from 19 polysomnogram-confirmed iRBD patients(male:female 16:3; mean age 66.6 ± 7.0 years) and 20 age-matched healthy controls(male:female 5:15; mean age 63.7 ± 5.9 years). Gray matter volume(GMV) data were analyzed based on Statistical Parametric Mapping 8, using a voxel-based morphometry method and two-sample t-test and multiple regression analysis. Compared with controls, iRBD patients had increased GMV in the middle temporal gyrus and cerebellar posterior lobe, but decreased GMV in the Rolandic operculum, postcentral gyrus, insular lobe, cingulate gyrus, precuneus, rectus gyrus, and superior frontal gyrus. iRBD duration was positively correlated with GMV in the precuneus, cuneus, superior parietal gyrus, postcentral gyrus, posterior cingulate gyrus, hippocampus, lingual gyrus, middle occipital gyrus, middle temporal gyrus, and cerebellum posterior lobe. Furthermore, phasic chin electromyographic activity was positively correlated with GMV in the hippocampus, precuneus, fusiform gyrus, precentral gyrus, superior frontal gyrus, cuneus, inferior parietal lobule, angular gyrus, superior parietal gyrus, paracentral lobule, and cerebellar posterior lobe. There were no significant negative correlations of brain GMV with disease duration or electromyographic activity in iRBD patients. These findings expand the spectrum of known gray matter modifications in iRBD patients and provide evidence of a correlation between brain dysfunction and clinical manifestations in such patients. The protocol was approved by the Ethics Committee of Huashan Hospital(approval No.

关键词： nerve regeneration idiopathic rapid Eye movement sleep behavior disorder synucleinopathies magnetic resonance imaging gray matter volume statistic parametric mapping voxel-based morphometry structure Parkinson’s disease neurodegenerative diseases neural regeneration

Passive Eye movements induced by electromagnetic force(EMF) in rats

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Zoological Research 2019年第3期40卷 211-218页

作者： Yue Yu Jun Huang Chun-Ming Zhang Tian-Wen Chen David S.Sandlin Shao-Xun Wang Alberto A.Arteaga Jerome Allison Yang Ou Susan Warren Paul May Hong Zhu Wu Zhou Departments of Otolaryngology and Communicative Sciences University of Mississippi Medical CenterJackson MS 39216USA Department of Otolaryngology First Affiliated HospitalShanxi Medical UniversityTaiyuan Shanxi 030001China MD/PhD Program University of Mississippi Medical CenterJackson MS 39216USA Pharmacology and Toxicology University of Mississippi Medical CenterJackson MS 39216.USA Neurobiology and Anatomical Sciences University of Mississippi Medical CenterJackson MS 39216USA Neurology University of Mississippi Medical CenterJackson MS 39216USA

Accurate information on Eye position in the orbit is available from visual feedback,efference copy of the oculomotor commands and proprioceptive signals from the extraocular muscles (EOM).Whereas visual feedback and oculomotor commands have been extensively studied,central processing of EOM proprioceptive signals remains to be elucidated.A challenge to the field is to develop an approach to induce passive Eye movements without physically contacting the Eyes.A novel method was developed to generate passive Eye movements in rats.A small rare-earth magnet disk (0.7 mm diameter,0.5 mm thickness) was attached to the surface of a rat's Eyeball.A metal rod (5 mm diameter) wrapped with an electromagnetic (EM) coil was placed near the magnet (8-15 mm).By passing currents to the EM coil,electromagnetic force (EMF) was generated and acted upon the magnet and induced passive Eye movements.The EMF induced well-defined passive Eye movements,whose directions were dependent on current polarity and amplitudes and peak velocities were dependent on current intensity and duration.Peak velocities of the EMF-induced Eye movements were linearly related to amplitudes,exhibiting main sequence relationships similar to that of saccades in awake rats and Eye movements induced by electrical microstimulation of the abducens nucleus in anesthetized rats.Histological examination showed that repetitive EMF stimulations did not appear to result in damages in the EOM fibers.These results validated the EMF approach as a novel tool to investigate EOM proprioceptive signals and their roles in visual localization and gaze control.

关键词： Eye movement Proprioception Extraocular muscles Stretch reflex

Abnormalities of interhemispheric functional connectivity in individuals with acute Eye pain: a resting-state fMRI study

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International Journal of Ophthalmology(English edition) 2019年第4期12卷 634-639页

作者： Zhi-Zhang Dong Fei-Yin Zhu Wen-Qing Shi Yong-Qiang Shu Lin-Long Chen Qing Yuan Qi Lin Pei-Wen Zhu Kang-Cheng Liu You-Lan Min Lei Ye Yi Shao Department of Ophthalmology the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Department of Ophthalmology the First Affiliated Hospital of Nanchang University Department of Clinical Medicine Queen Mary College of Nanchang University Department of Radiology the First Affiliated Hospital of Nanchang University

AIM: To study the changes of the resting state functional connectivity(rsFC) between acute Eye pain(EP) subjects and healthy controls(HCs) in the two hemispheres by using voxel-mirrored homotopic connectivity(VMHC) method.METHODS: Totally 20 patients with EP and 20 HCs were enrolled, sex, age, and education were matched, and all subjects were examined by functional magnetic resonance imaging(fMRI) scans at resting-state. The changes of rs FC between the hemispheres were evaluated by the VMHC method according to Gaussian random field(GRF) theory. In order to identify the VMHC, as biomarkers for distinguishing EP and from HC, the receiver operating characteristic curves(ROC) had been analyzed. The relationships were evaluated with Pearson correlation analysis between the mean VMHC signal values and clinical features in these patients.RESULTS: By comparing with health subjects, the significant decreased VMHC values was observed in lingual/calcarine(Brodmann area, BA 30), precentral/postcentral gyrus(PreCG/PosCG; BA 4) and medial frontal gyrus(MFG; BA 8)(false discovery rate corrected <0.01) in the acute EP individuals. The accuracy of area under curve was excellent indicated by the ROC curve analysis of each brain regions.CONCLUSION: Our study demonstrates preliminary evidence of disrupted interhemispheric rsFC in acute EP in sensorimotor and limbic system and somatosensory cortex, which might give some useful information for understanding the neurological mechanisms in acute EP individuals.

关键词： acute Eye pain voxel-mirrored homotopic connectivity functional magnetic resonance imaging resting state

Eye metastasis in lung adenocarcinoma mimicking anterior scleritis:A case report

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World Journal of Clinical Cases 2020年第2期8卷 410-414页

作者： Hua-Fei Chen Wen-Xian Wang Xiao-Feng Li Li-Xin Wu You-Cai Zhu Kai-Qi Du Chun-Wei Xu Thoracic Disease Center Zhejiang Rongjun HospitalJiaxing 314000Zhejiang ProvinceChina Department of Chemotherapy Zhejiang Cancer HospitalHangzhou 310022Zhejiang ProvinceChina Department of Pathology Fujian Cancer HospitalFujian Medical University Cancer HospitalFuzhou 350014Fujian ProvinceChina

BACKGROUND The Eye is a rare site for lung cancer metastasis. Indeed, ocular metastasis is one of the greatest challenges to quality of life in a cancer patient. Here we present a patient with lung adenocarcinoma and ocular metastasis.CASE SUMMARY The patient was a 70-year-old man diagnosed with lung adenocarcinoma who developed Eye metastasis mimicking anterior scleritis. Brain magnetic resonance imaging showed an abnormal signal in the right Eye. Based on next generation sequencing of the surgical specimen, the patient was shown to have a KRAS point mutation(p.G12D).CONCLUSION Multidiscipline expertise collaboration is needed to make the early diagnosis and determine the prompt treatment in patients. We hope to increase the awareness of the possibility of lung cancer metastasizing to the Eye.

关键词： Eye Metastases Non-small cell lung cancer KRAS mutation Case report

Atropine 0.01% Eye drops slow myopia progression: a systematic review and Meta-analysis

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International Journal of Ophthalmology(English edition) 2019年第8期12卷 1337-1343页

作者： Ying Zhao Kai Feng Rui-Bao Liu Jin-Hua Pan Lai-Lin Zhang Zhu-Ping Xu Xue-Jing Lu Chengdu University of Traditional Chinese Medicine Chengdu610075Sichuan ProvinceChina Beijing University of Chinese Medicine Beijing100029China West China Hospital Sichuan UniversityChengdu610041Sichuan ProvinceChina

AIM: To evaluate the effects of atropine 0.01% on slowing myopia progression. METHODS: We searched for relevant studies in the Cochrane Library, PubMed, Embase, Ovid, CBM, CNKI, VIP and Wan Fang Data in Chinese. A supplementary search was conducted in OpenGrey(System for Information on Grey Literature in Europe), the ISRCTN registry, Clinical Trials.gov, and the WHO International Clinical Trials Registry Platform(ICTRP) from the dates of inception to June 30, 2018. RESULTS: Seven randomized controlled trials(RCTs) with a total of 1079 subjects were included(505 in the atropine 0.01% group and 574 in the control group). The results showed that the atropine 0.01% group exhibited significantly greater control of axial growth than the control group (MD=-0.12, 95%CI(-0.19,-0.06))There was also a statistically significant difference between the atropine 0.01% and control groups in the changes in axial length [MD=-0.14, 95%CI(-0.25,-0.03)], but the quality of evidence was low. There were no significant differences between the atropine 0.01% and control groups in the overall effect with respect to diopter value, change in diopter, distance vision and intraocular pressure (MD=0.08, 95%CI(-0.27, 0.42);MD=0.09, 95%CI(-0.17, 0.36);MD=-0.01, 95%CI(-0.02, 0.00);MD=0.08, 95%CI(-0.56,0.40))The sensitivity analysis showed that the conclusion of the Meta-analysis is relatively stable. With respect to adverse events, there were significant differences between the atropine 0.01% and control groups (OR=0.26, 95%CI(0.11, 0.61))CONCLUSION: Based on the available evidence, atropine 0.01% Eye drops offer benefits in controlling axial growth and safety without causing significant differences in diopter values, distance vision and intraocular pressure.

关键词： atropine 0.01% Eye drops myopia systematic review Meta-analysis