Eye metastasis in lung adenocarcinoma mimicking anterior scleritis:A case report

作     者：Hua-Fei Chen Wen-Xian Wang Xiao-Feng Li Li-Xin Wu You-Cai Zhu Kai-Qi Du Chun-Wei Xu 

作者机构：Thoracic Disease CenterZhejiang Rongjun HospitalJiaxing 314000Zhejiang ProvinceChina Department of ChemotherapyZhejiang Cancer HospitalHangzhou 310022Zhejiang ProvinceChina Department of PathologyFujian Cancer HospitalFujian Medical University Cancer HospitalFuzhou 350014Fujian ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2020年第8卷第2期

页      面：410-414页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported by Science and Technology Planning Project of Zhejiang Province,No.LGF19H160002 Medical Scientific Research Foundation of Zhejiang Province of China,No.2019RC027 Scientific Research Foundation of Zhejiang Medical Association,No.2018ZYC-B5 Technology Bureau of Jiaxing City of Zhejiang Province,No.2017BY18050,No.2018AD32163,and No.2019AD32266 Xisike-Hanson Cancer Research Foundation,No.Y-HS2019-20 

主　　题：Eye Metastases Non-small cell lung cancer KRAS mutation Case report 

摘      要：BACKGROUND The eye is a rare site for lung cancer metastasis. Indeed, ocular metastasis is one of the greatest challenges to quality of life in a cancer patient. Here we present a patient with lung adenocarcinoma and ocular metastasis.CASE SUMMARY The patient was a 70-year-old man diagnosed with lung adenocarcinoma who developed eye metastasis mimicking anterior scleritis. Brain magnetic resonance imaging showed an abnormal signal in the right eye. Based on next generation sequencing of the surgical specimen, the patient was shown to have a KRAS point mutation(p.G12D).CONCLUSION Multidiscipline expertise collaboration is needed to make the early diagnosis and determine the prompt treatment in patients. We hope to increase the awareness of the possibility of lung cancer metastasizing to the eye.