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epidermoid Cyst of the Auricle: A Common Cyst at a Rare Site

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International Journal of Otolaryngology and Head & Neck Surgery 2018年第6期7卷 344-349页

作者： Vinson Louis Gonzaga Fernandes Nina Margarida De Gouveia Pinto Ombretta Barreto Joevito Furtado Siddhartha Basuroy Department of Otorhinolaryngology and Head & Neck Surgery Goa Medical College and Hospital Bambolim India

epidermoid cysts are benign, developmental, superficial cysts found commonly on the face, trunk and neck. Its presence on the ear lobe is very rare. We shall describe the occurrence of an epidermoid cyst on the auricle along with the presence of a dermoid cyst over the occipital scalp and elaborate on the patient presentation, diagnosis, management along with the post-operative follow up.

关键词： epidermoid Cyst Lobule Auricle

epidermoid Cyst of the Testis 5-Year Follow-Up Results in Adults

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Open Journal of Urology 2019年第4期9卷 69-76页

作者： Caner Ediz Aysenur Ihvan Bulent Kati Serkan Akan Omer Yilmaz Department of Urology Health Sciences University Sultan Abdulhamid Han Education and Research Hospital Istanbul Turkey Department of Pathology Health Sciences University Umraniye Education and Research Hospital Istanbul Turkey Department of Urology Harran University Research Hospital Sanliurfa Turkey

Background: In this study, we aimed to share our experiences in patients with epidermoid cyst of the testis. We report the demographic and clinical characteristics and the long term results in patients with epidermoid cysts. Materials and Methods: Thirteen patients with epidermoid cyst of the testis treated between June 2000 and January 2018 were retrospectively evaluated. Ten patients with available data were included in the study. Patients’ age, scrotal localization of symptoms, physical examination findings, serum tumor marker levels, pathology results and follow-up periods were recorded. Results: The current cohort consisted of 10 patients. The mean age at diagnosis was 29.7 years (range, 20 to 53 years). Eighty percent of the lesions were localized to the left hemiscrotum and 20% to the right hemiscrotum. One patient had a history of unilateral undescended testis. Serum tumor markers were normal in all patients. The mean scrotal mass lesion volume at diagnosis was 28 mm3 (range, 13 to 51 mm3). The mean follow-up period was 66.9 months (range, 12 to 216 months). Conclusions: epidermoid cyst of the testis should be kept in mind, particularly in patients with lesions negative for tumor markers and radiological findings typical of epidermoid cysts. Annual follow-up is not required.

关键词： epidermoid Cyst Testis Germ Cell Tumor

epidermoid Cyst of Cerebellopontine Angle

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影像诊断与介入放射学 2017年第6期26卷 504-506页

作者：关键中山大学附属第一医院医学影像科广东广州510080

Synonyms: epidermoid tumor,non-neoplastic inclusion cyst, congenital cholesteatoma of the cerebellopontine angle ***: Congenital lesion arising from inclusion of ectodermal epithelial elements at time of neural tube closure during 3rd to 5th week of embryonic life, resulting in migration abnormalities of epiblastic *** imaging appearance:(1)Signal shows an insinuating cisternal lesion with low T1, high T2 close to that of cerebrospinal fluid (CSF).(2)FLAIR shows incomplete or absent attenuation.(3)Diffusion-weighted imaging shows epidermoid cyst has restricted diffusion(high-signal lesion).Other key facts:(1)3rd most common cerebellopontine angle-internal auditory canal (CPA-IAC) mass.(2)1% of all intracranial tumors.

关键词： Synonyms: epidermoid tumor,non-neoplastic inclusion cyst

Differential Anticancer Effect of an Apple Extract (Applephenon<sup>&reg</sup>), Polyphenols and Isoflavones on Normal Human Keratinocytes and epidermoid Cancer Cells

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Journal of Cancer Therapy 2019年第6期10卷 476-493页

作者： John J. Wille Mark A. Berhow Jong Y. Park Bioplast Medical LLC Chesterfield NJ USA ARS USDA Peoria IL USA Moffitt Cancer Center Tampa FL USA

Applephenon®, a purified extract prepared from green apples, was examined for its cytotoxicity and inhibitory effects on the proliferation of cultures of normal human keratinocytes and several epidermoid cancer cell lines. Our HPLC studies demonstrated a high content of phenolic compounds (>65%), including catechin, epicatechin, caffeic acid and phloretin as well as polyphenols such as proanthocyanidins. Applephenon® demonstrated a greater cytotoxic effect against HeLa, A431 cancer cell lines and HaCaT, an immortalized keratinocyte cell line than serum-free cultures of proliferating normal human keratinocytes (NHK). Proliferation of NHK was inhibited at concentrations above 0.0013% while concentrations above 0.005% were cytotoxic. By contrast, Applephenon® solutions above 0.00025% killed each of the cancer cell lines. Treated cells displayed increased intercellular separation and evidence of keratinizing stratification. We also tested the effect of epicatechin, and two isoflavonoids, genistein and daidzein, on cancer cell lines. Hela cells were more sensitive to epicatechin and genistein inhibition of cell growth and cytotoxicity than were NHK. Daidzein at these concentrations had little effect on cancer cells. These results indicate that Applephenon® and some of its phenolic components have selective anticancer activity.

关键词： ApplephenonTM (AP-SH Grade) Cytotoxicity Epicatechin Epidermal Keratinocytes epidermoid Cancer Cell Lines (A431 HaCaT HeLa) Genistein Polyphenols

A Case of Giant epidermoid Cyst in the Floor of the Mouth That Caused Severe Obstructive Sleep Apnea Syndrome

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Open Journal of Stomatology 2014年第5期4卷 243-248页

作者： Norimichi Nakamoto Tsuyoshi Sato Yoshie Sano Makoto Kabeya Yuichiro Enoki Yasuaki Sakata Tetsuya Yoda Department of Oral and Maxillofacial Surgery Saitama Medical School Moroyama Japan Division of Oral and Maxillofacial Biopathological Surgery Tottori University Faculty of Medicine Yonago Japan

We describe here, a case with a giant epidermoid cyst in the floor of the mouth that caused severe obstructive sleep apnea syndrome (OSAS). A 37-year-old man was referred to our clinic because of a swelling in the floor of his mouth and sleep apnea syndrome. The occurrence of breathing disorders and daytime drowsiness was monitored to evaluate his OSAS 1 day before and 7 days after surgery. Before surgery, the apnea-hyponea index (AHI) and Epworth Sleepiness Scale (ESS) were 45.7 and 22, respectively. The clinical diagnosis was a dermoid or an epidermoid cyst that caused severe OSAS. Under general anesthesia, the patient underwent intraoral surgical removal of the cyst, along with aspiration to reduce the mass. After surgery, his sleep apnea syndrome was significantly improved. The postoperative AHI and ESS were 5.5 and 7, respectively. As of 2 years after the operation, there was no evidence of recurrence.

关键词： epidermoid Cyst Obstructive Sleep Apnea Syndrome Apnea-Hyponea Index

Malignant epidermoid arising from the third ventricle:A case report

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World Journal of Radiology 2019年第5期11卷 74-80页

作者： Samadhan Pawar Chaitanya Borde Atul Patil Rajnish Nagarkar Department of Radiodiagnosis HCG Manavata Cancer Centre

BACKGROUND Third epidermoid tumors are a rare finding. The appearance of these tumors often makes them difficult to diagnose, and thus they require multimodality imaging. CASE SUMMARY A 48-year-old male patient reported to our hospital with complaints of vomiting and severe headache. The patient also complained of involuntary micturition for the past five days. We used a combination of computed tomography (CT) and magnetic resonance imaging (MRI) imaging modalities to confirm the presence of a malignant epidermoid cyst arising from the third ventricle. A contrastenhanced CT of the head demonstrated minimal perilesional enhancement while an MRI revealed a large, lobulated and septated T2 hyperintense mass arising from the third ventricle. The maximum size of the lesion measured 73 mm × 65 mm × 64 mm in size. CONCLUSION Malignant epidermoid arising from the third ventricle in an adult male was reported using a combination of CT, MRI, and MR spectroscopy.

关键词： epidermoid Third ventricle Magnetic resonance imaging Case report

Penile epidermoid Cyst Consisted of Multiple Foci: A Case Report

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Journal of Cosmetics, Dermatological Sciences and Applications 2012年第3期2卷 214-215页

作者： Akiou Okumura Kiyoshi Takagawa Hideki Fuse Department of Clinical Laboratory Kurobe City Hospital Toyama Japan Department of Urology Graduate School of Medicine and Pharmaceutical Sciences for Research University of Toyama Toyama Japan Department of Urology Kurobe City Hospital Toyama Japan

Penile epidermoid cysts are uncommon, and a small number of cases have been reported worldwide. We present the first documented patient with a penile epidermoid cyst which consisted of multiple focuses. A 37-year-old man presented to our department with a chief complaint of an asymptomatic, soft mass in the ventral part of the penis. The mass was nontender, freely movable and measuring 3 cm within the dermis. MRI (magnetic resonance imaging) revealed a high signal intensity on both T1- and T2-weighted images. Excision of the cyst was performed under local anesthesia. Macroscopically, the cut surface of the mass appeared to be full of a cheese-like material and the cyst consisted of multiple focuses. The cyst did not contain skin appendages. The pathological diagnosis was an epidermoid cyst of the penis. No recurrence has been noted in the year since the operation.

关键词： Penis epidermoid Cyst Multiple Focuses

Sublingual epidermoid cyst—a case report

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Health 2010年第6期2卷 613-614页

作者： Satheesh kumar Bhandary Vadisha Bhat M. Shwetha Shenoy 不详

In this article we present the case of an epidermoid cyst of sublingual space along with submental extension in a 35 year old lady who presented with a mass in the oral cavity. On examination a mass was seen on the floor of the mouth displacing the tongue superiorly. Diffuse fullness was noted in the submental region. The lesion was excised under general anaesthesia with nasotracheal intubation. The entire mass was removed intra orally. The histological features were suggestive of epidermoid cyst. The patient did well postoperatively and no recurrence was seen during 8 months follow up.

关键词： Sublingual epidermoid Cyst Intraoral Approach

Very rare upperdorsal intramedullary epidermoid with paraplegia: a case report

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Neuroimmunology and Neuroinflammation 2018年第4期5卷 36-40页

作者： Md.Atikur Rahman Bipin Kumar Chaurasia Md.Arif Hossain Saequa Habib Kanak Kanti Barua Department of Neurosurgery Bangabandhu Sheikh Mujib Medical UniversityDhaka 1000Bangladesh Department of Pathology Bangabandhu Sheikh Mujib Medical UniversityDhaka 1000Bangladesh

Intramedullary upperdorsal epidermoid tumor is very rare. As far as we know, a small number of epidermoid tumors in the spinal cord have been reported in the journal for a long time. Most of the time, the spinal cord epidermoids are intradural extramedullary. We are reporting a case of a 21-year-old young man with paraplegia and upper dorsal pain for 6 months with normal physical findings. Magnetic resonance imaging scan shows that spinal intramedullary space occupying lesions in the dorsal 2/3 (D2/3) level. Total clearance was accomplished by performing laminectomy. Day to day paraplegia was improved. Histopathology was confirmed as an epidermoid tumor from two different centers.

关键词： Upperdorsal epidermoid intramedullary