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The Journal of Biomedical Research 2016年第3期30卷 191-196页

作者： Qiu Sheng Jun Yang Qiaoling Zhao Fen Li Center of Maternal and Child Health First Affiliated Hospital of Xi'an Jiaotong University Department of Ultrasound First Affiliated Hospital of Xi'an Jiaotong University

The aim of this study was to evaluate the effects of low-dose tibolone therapy on ovarian area, uterine volume and endometrial thickness, and define the cut-off value of endometrial thickness for curettage during uterine bleeding. We followed 619 postmenopausal women, aged 40-60 years, for two years. There were 301 subjects in the low-dose tibolone treatment group and 318 subjects in the control group. The ovarian area, uterine volume and endometrial thickness in all participants were measured by transvaginal ultrasound prior to, one and two years post enrollment, respectively. Endometrial specimens were collected from all subjects with abnormal uterine bleeding during the follow-up period. We found that the uterine volume in the treatment group was greater than that in the control group, and the difference was significant （P〈0.05）, but there were no significant differences in ovarian area and endometrial thickness between the two groups （P〉0.05）. When the cut-off value for endometrial thickness was 7.35 ram, the sensitivity and specificity were 100% and 79.07%, respectively, and 85.71% and 93.02% when 7.55 mm was set as the cut-offduring tibolone therapy. The results indicate that low-dose tibolone therapy may postpone uterine atrophy and the cut-off value of endometrial thickness may be appropriately adjusted for curettage.

关键词： low-dose tibolone ovarian area uterine volume endometrium dynamic monitoring cut-off value

dynamic monitoring of serum liver function indexes in patients with COVID-19

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World Journal of Clinical Cases 2021年第7期9卷 1554-1562页

作者： Hao Lin Ling-Jie Wu Shun-Qi Guo Rui-Lie Chen Jing-Ru Fan Bin Ke Ze-Qun Pan Department of Gastroenterology Shantou Central HospitalShantou 515000Guangdong ProvinceChina Department of Infectious Disease Shantou Central HospitalShantou 515000Guangdong ProvinceChina Department of Emergency Shantou Central HospitalShantou 515000Guangdong ProvinceChina Department of Ultrasonography Shantou Central HospitalShantou 515000Guangdong ProvinceChina Department of Pediatrics Shantou Central HospitalShantou 515000Guangdong ProvinceChina

BACKGROUND Some patients with the novel 2019 coronavirus disease(COVID-19)display elevated liver enzymes.Some antiviral drugs that can be used against COVID-19 are associated with a risk of hepatotoxicity.AIM To analyze the clinical significance of the dynamic monitoring of the liver function of patients with COVID-19.METHODS This was a retrospective study of patients diagnosed with COVID-19 in January and February 2020 at the Department of Infection,Shantou Central Hospital.The exclusion criteria for all patients were:(1)History of chronic liver disease;(2)History of kidney disease;(3)History of coronary heart disease;(4)History of malignancy;or(5)History of diabetes.The serum levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST),γ-glutamyltransferase,and total bilirubin of patients with COVID-19 were measured on days 1,3,7 and 14 after admission,and compared to non-COVID-19 patents.RESULTS Twelve patients with COVID-19(seven men and five women)and twelve controls(eight men and four women)were included.There were one,two,and nine patients with severe,mild,and moderate COVID-19,respectively.There were no differences in age and sex between the two groups(both P>0.05).No significant differences were found in albumin,ALT,AST,γ-glutamyltransferase,or total bilirubin between the controls and the patients with COVID-19 on day 1 of hospitalization(all P>0.05).Serum albumin showed a decreasing trend from days 0 to 7 of hospitalization,reaching the lowest level on day 7.Total bilirubin was higher on day 3 than on day 7.ALT,AST,andγ-glutamyltransferase did not change significantly over time.The severe patient was observed to have ALT levels of 67 U/L and AST levels of 75 U/L on day 7,ALT of 71 U/L and AST of 35 U/L on day 14,and ALT of 210 U/L and AST of 123 U/L on day 21.CONCLUSION Changes in serum liver function indicators are not obvious in the early stage of COVID-19,but clinically significant changes might be observed in severe COVID-19.

关键词： COVID-19 Liver function dynamic monitoring Disease severity Kidney disease Index

Multi-parameter numerical simulation of dynamic monitoring of rock deformation in deep mining

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International Journal of Mining Science and Technology 2016年第5期26卷 851-855页

作者： Li Juanjuan Hu Mingshun Ding Enjie Kong Wei Pan Dongming Chen Shenen IoT Perception Mine Research Center China University of Mining ＆ Technology Xuzhou 221008 China The National and Local Joint Engineering Laboratory of lnternet Application Technology on Mine China University of Mining ＆ Technology Xuzhou 221008 China School of Resources and Geosciences China University of Mining ＆ Technology Xuzhou 221116 China City Exploring and Surveying Institute ofJinan Jinan 250013 China Department of Civil Engineering University of North Carolina at Charlotte Charlotte 28223 USA

The level of deformation development of surrounding rocks is a vital predictor to evaluate impending coal mine disasters and it is important to establish accurate measurements of the deformed status to ensure coal mine safety. Traditional deformation monitoring methods are mostly based on single parameter, in this paper, multiple approaches are integrated: firstly, both electric and elastic models are established,from which electric field distribution and seismic wave recording are calculated and finally, the resistivity profiles and source position information are determined using inversion methods, from which then the deformation and failure of mine floor are evaluated. According to the inversion results of both electric and seismic field signals, multiple-parameter dynamic monitoring of surrounding rock deformation in deep mine can be performed. The methodology is validated using numerical simulation results which shows that the multi-parameter dynamic monitoring methods have better results for surrounding rock deformation in deep mine monitoring than single parameter methods.

关键词： dynamic monitoring Electric numerical simulation Elastic numerical simulation Inversion methods

Remote sensing-based dynamic monitoring and environmental change of wetlands in southern Mongolian Plateau in 2000‒2018

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China Geology 2021年第2期4卷 353-363页

作者： Wen-hui Jie Chun-lei Xiao Ce Zhang En Zhang Jing-yue Li Bing Wang Hai-wei Niu Shuang-fa Dong Airborne Survey and Remote Sensing Center of Nuclear Industry Shijiazhuang 050002China Hebei Key Laboratory of Airborne Survey and Remote Sensing Technology Shijiazhuang 050002China China Aero Geophysical Survey and Remote Sensing Center for Natural Resources China Geological SurveyBeijing 100083China

The environmental change in the wetlands in the southern Mongolian Plateau has important impacts on the environment of North China and even the entire Northeast Asia,from which the global climate change can be understood on a large scale,especially the climate change in the Mongolian Plateau.This study extracted the information on the wetlands from three stages of remote sensing images(also referred to as RS images)of the study area,including Enhanced Thematic Mapper Plus(ETM+)images of 2000,TM images of 2010,and Landsat 8 Operational Land Imager(OLI)images of 2018.As indicated by the extraction results,the area of wetlands decreased from 796.90 km^(2) of 2000 to 666.24 km^(2) of 2018 at a rate of 7.26 km^(2)/a.The reduced area is 130.66 km^(2),which is about 16.4%reduction.And the patch number of wetlands decreased from 731 of 2000 to 316 of 2018 in the study area,approximately 56.8%reduction(415 patches),and the decrease in the area of the wetlands mainly occurred in the northwest endorheic region.In terms of wetland types,the change of the wetlands was dominated by the decrease of lacustrine wetlands,of which the area and patch number decreased by 106.2 km^(2) and 242,respectively.Furthermore,the area of the lacustrine wetlands decreased at the highest rate of 8.70 km^(2)/a in 2010‒2018.From the perspective of spatial distribution,the wetlands in the western part shrunk more notably than those in the eastern part as a whole in the study area.According to local meteorological data,the precipitation gently decreased and the temperature increased(about 1.7℃)from 1975-2018.Overall,the decrease in the area of the wetlands and the temperature rises in the study area were mainly driven by the Mongolian monsoon climate,reduction in precipitation,and human activities.

关键词： Wetlands Environmental change Global climate change Remote sensing dynamic monitoring Southern Mongolian Plateau

Research on dynamic monitoring Algorithm of Visual Safety Distance in Highway

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Journal of Geoscience and Environment Protection 2016年第11期4卷 6-12页

作者： Jiajia Zhang Yu Liu Jianming Li Yanhua Guan Meteorological Technology and Equipment Center in Hebei Province Shijiazhuang China

To develop the dynamic monitoring algorithm of visual safety distance in highway, by using the highway video traffic monitoring system, the research platform of four kinds of terrain environment in plateau, mountainous area, plain and coastal area is established. Results show that through the contrast between the sample data and visibility train of thought, based on the theory of mathematical morphology, expressway visibility dynamic monitoring image information system can be established. Based on the theory of the measurement of the basic formula of visibility, the dynamic model of the optimization is established, set up 200 meters distance visual observation target system, research visual range detection algorithm process.

关键词： The Highway Visual Range dynamic monitoring Mathematical Model

An Object-Level Approach Improved by Quadtree to dynamic monitoring of Mining Area Expansion

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An Object-Level Approach Improved by Quadtree to Dynamic Mon...

A molecular probe carrying anti-tropomyosin 4 for early diagnosis of cerebral ischemia/reperfusion injury

2013年中国智能自动化学术会议

作者： Liang Huang Yuanmin Fang Xiaoqing Zuo Xueqin Yu Faculty of Land Resource Engineering Kunming University of Science and Technology

An object-level approach improved by quadtree to dynamic monitoring of mining area expansion is proposed.In order to improve the efficiency and quality of objects acquired from high spatial resolution remote sensing image, multi-scale segmentation combined with quadtree segmentation is used to obtain objects of multitemporal remote sensing images;Then object-oriented image analysis method which takes into account the spatial relationship between ground objects is used in multitemporal remote sensing images to extract mining information respectively;Finally,overlay is use in mining areas extraction respectively, and Inter-erase operation is used to obtain result of mining expansion.Experiments are carried out in remote sensing images from a certain phosphate area of Anning, and the results prove that method was proposed in this paper is feasible and effective.

关键词： Mining area expansion dynamic monitoring Quadtree segmentation Orient-object Multi-scale segmentation

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Neural Regeneration Research 2023年第6期18卷 1321-1324页

作者： Teng-Fei Yu Kun Wang Lu Yin Wen-Zhe Li Chuan-Ping Li Wei Zhang Jie Tian Wen He Department of Ultrasound Beijing Tiantan HospitalCapital Medical UniversityBeijingChina CAS Key Laboratory of Molecular Imaging Institute of AutomationChinese Academy of SciencesBeijingChina State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijingChina Anhui Province Key Laboratory of Functional Coordinated Complexes for Materials Chemistry and Application School of Chemical and Environmental EngineeringAnhui Polytechnic UniversityWuhuAnhui ProvinceChina Beijing Advanced Innovation Center for Big Data-Based Precision Medicine School of Engineering MedicineBeihang UniversityBeijingChina

In vivo imaging of cerebral ischemia/reperfusion injury remains an important challenge.We injected porous Ag/Au@SiO_(2) bimetallic hollow nanoshells carrying anti-tropomyosin 4 as a molecular probe into mice with cerebral ischemia/reperfusion injury and observed microvascular changes in the brain using photoacoustic imaging with ultrasonography.At each measured time point,the total photoacoustic signal was significantly higher on the affected side than on the healthy side.Twelve hours after reperfusion,cerebral perfusion on the affected side increased,cerebrovascular injury worsened,and anti-tropomyosin 4 expression increased.Twenty-four hours after reperfusion and later,perfusion on the affected side declined slowly and stabilized after 1 week;brain injury was also alleviated.Histopathological and immunohistochemical examinations confirmed the brain injury tissue changes.The nanoshell molecular probe carrying anti-tropomyosin 4 has potential for use in early diagnosis of cerebral ischemia/reperfusion injury and evaluating its progression.

关键词： cerebral ischemia/reperfusion injury diagnosis dynamic monitoring ischemic stroke middle cerebral artery occlusion molecular probe nanoshells photoacoustic imaging tropomyosin 4 ultrasound

Key Problems and Countermeasures in CO_(2)Flooding and Storage

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Acta Geologica Sinica(English Edition) 2023年第3期97卷 858-872页

作者： CHEN Huanqing Research Institute of Petroleum Exploration and Development PetroChinaBeijing 100083China

Based on literature research in combination with the practice of CO_(2)flooding and storage in Jilin Oilfield,this study assesses the key problems in CO_(2)flooding and storage,proposing the corresponding countermeasures from five aspects of CO_(2)gas source condition,namely geological condition evaluation,scheme design incoordination with other production methods,economic and effectiveness evaluation,together with dynamic monitoring and safety evaluation.The results show that CO_(2)flooding is the most economic and effective CO_(2)storage method.In eastern China,inorganic origin CO_(2)gas reservoirs are widely developed and are especially the most enriched in the Paleozoic carbonate rock strata and the Cenozoic Paleogene–Neogene system,which provide a rich resource base for CO_(2)flooding and storage.In the future,CO_(2)generated in the industrial field will become the main gas source of CO_(2)flooding and storage.The evaluation of geological conditions of oil and gas reservoirs is the basis for the potential evaluation,planning scheme design and implementation of CO_(2)flooding and storage.CO_(2)storage should be below the depth of 800 m,the CO_(2)flooding and storage effects in lowpermeability oil reservoirs being the best.CO_(2)geological storage mechanisms primarily consist of tectonic geological storage,bound gas storage,dissolution storage,mineralization storage,hydrodynamic storage and coalbed adsorption storage.The practice of CO_(2)flooding and storage in Jilin Oilfield demonstratesthat the oil increment by CO_(2)flooding is at least 24%higher than by conventional water flooding.The most critical factor determining the success or failure of CO_(2)flooding and storage is economic effectiveness,which needs to be explored from two aspects:the method and technology innovation along with the carbon peaking and carbon neutrality policy support.After CO_(2)is injected into the reservoir,it will react with the reservoir and fluid,the problem of CO_(2)recovery or overflow will occur,so the dynamic monitoring and

关键词： CO_(2)flooding and storage CO_(2)gas source low permeability reservoir economic effectiveness dynamic monitoring

PIMS:An Efficient Process Integrity monitoring System Based on Blockchain and Trusted Computing in Cloud-Native Context

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Computer Modeling in Engineering & Sciences 2023年第8期136卷 1879-1898页

作者： Miaomiao Yang Guosheng Huang Junwei Liu Yanshuang Gui Qixu Wang Xingshu Chen Cyber Science Research Institute of Sichuan University Chengdu610207China Cyber Science and Engineering of Sichuan University Chengdu610207China China Mobile(Suzhou)Software Technology China MobileSuzhou215163China

With the advantages of lightweight and high resource utilization,cloud-native technology with containers as the core is gradually becoming themainstreamtechnical architecture for information infrastructure.However,malware attacks such as Doki and Symbiote threaten the container runtime’s security.Malware initiates various types of runtime anomalies based on process form(e.g.,modifying the process of a container,and opening the external ports).Fortunately,dynamic monitoring mechanisms have proven to be a feasible solution for verifying the trusted state of containers at runtime.Nevertheless,the current routine dynamic monitoring mechanisms for baseline data protection are still based on strong security assumptions.As a result,the existing dynamicmonitoringmechanismis still not practical enough.To ensure the trustworthiness of the baseline value data and,simultaneously,to achieve the integrity verification of the monitored process,we combine blockchain and trusted computing to propose a process integrity monitoring system named IPMS.Firstly,the hardware TPM 2.0 module is applied to construct a trusted security foundation for the integrity of the process code segment due to its tamper-proof feature.Then,design a new format for storing measurement logs,easily distinguishing files with the same name in different containers from log information.Meanwhile,the baseline value data is stored on the blockchain to avoidmalicious damage.Finally,trusted computing technology is used to perform fine-grained integrity measurement and remote attestation of processes in a container,detect abnormal containers in time and control them.We have implemented a prototype system and performed extensive simulation experiments to test and analyze the functionality and performance of the PIMS.Experimental results show that PIMS can accurately and efficiently detect tampered processes with only 3.57% performance loss to the container.

关键词： Blockchain-based protection dynamic monitoring remote attestation integrity verification

Microscopic dynamic observation of adhesion hysteresis friction and exploration of the influence of different pressures on friction transmission

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Friction 2021年第4期9卷 758-773页

作者： Cun-ao FENG De-kun ZHANG Kai CHEN School of Mechatronic Engineering China University of Mining and TechnologyXuzhou 221116China Department of Mechanical Engineering University of British Columbia Vancouver V6T1Z4Canada School of Materials Science and Engineering China University of Mining and Technology Xuzhou 221116China

The mechanism of adhesive friction between viscoelastic materials is a key question.In this study,the friction process of the adhesive interface between a friction lining and a wire rope is dynamically observed in real time to analyze the adhesion hysteresis friction intuitively and quantitatively.The adhesion is determined by the state of motion,while the relative displacement of the wire rope and lining is used to find the magnitude of the adhesive friction.The hysteresis friction is reflected by the internal deformation of the lining.The magnitude of the hysteresis friction is determined by the displacement difference(Ax)in the sliding direction of two marked points at different distances from the contact surface.The results show that the adhesion friction is proportional to the loss modulus and the hysteresis friction is proportional to the ratio of the loss modulus to the square of the storage modulus(E"/(E'^(2))).The frictional vibration first decreases and then increases with the increase in pressure.The K25 lining has the highest adhesion hysteresis friction and minimal frictional vibration.The result provides a simple and intuitive method for research into the friction transmission and vibration of viscoelastic materials.

关键词： adhesion hysteresis friction viscoelasticity frictional vibration dynamic monitoring