检索结果-南通市图书馆

Prevalence and risk factors of osteoporosis detected by Dual-energy X-ray absorptiometry among Chinese patients with primary biliary cholangitis

引用

World Journal of Gastroenterology 2023年第29期29卷 4580-4592页

作者： Jia-Liang Chen Yao Liu Yu-Fei Bi xian-Bo Wang Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China

BACKGROUND Osteoporosis is an extrahepatic complication of primary biliary cholangitis(PBC)that increases the risk of fractures and mortality.However,Epidemiological studies of osteoporosis in patients with PBC in China and the Asia-Pacific region is lack.AIM To assess the prevalence and clinical characteristics of osteoporosis in Chinese patients with PBC.METHODS This retrospective analysis included consecutive patients with PBC from a tertiary care center in China who underwent bone mineral density(BMD)assessment using Dual-energy X-ray absorptiometry between January 2013 and December 2021.We defined subjects with T-scores≤-2.5 in any sites(L1 to L4,femoral neck,or total hip)as having osteoporosis.Demographic,serological,clinical,and histological data were collected.Independent risk factors for osteoporosis were identified by multivariate logistic regression analysis.RESULTS A total of 268 patients with PBC[236 women(88.1%);mean age,56.7±10.6 years;163 liver biopsies(60.8%)]were included.The overall prevalence of osteoporosis in patients with PBC was 45.5%(122/268),with the prevalence of osteoporosis in women and men being 47.0%and 34.4%,respectively.The prevalence of osteoporosis in postmenopausal women was significantly higher than that in premenopausal women(56.3%vs 21.0%,Px(BMI),splenomegaly,gastroesophageal varices,ascites,Mayo risk score,histological stage,alanine aminotransferase,albumin,bilirubin,platelet and prothrombin activity.Multivariate regression analysis identified that older age,lower BMI,previous steroid therapy,higher Mayo risk score,and advanced histological stage as the main independent risk factors for osteoporosis in PBC.CONCLUSION Osteoporosis is very common in Chinese patients with PBC,allowing for prior screening of BMD in those PBC patients with older age,lower BMI,previous steroid therapy and advanced liver disease.

关键词： Primary biliary cholangitis Osteoporosis Bone mineral density Dual-energy X-ray absorptiometry Prevalence Chinese

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Association between body mass index and body fat measured by Dual-energy X-ray absorptiometry (DxA) in China: a systematic review and meta-analysis

引用

Global Health Journal 2023年第2期7卷 61-69页

作者： xiaomin Sun Na Yan Wen Peng Tuan T Nguyen Lu Ma Youfa Wang International Obesity and Metabolic Disease Research Center Global Health InstituteSchool of Public HealthXi'an Jiaotong UniversityXi'anShaanxi 710061China Nutrition and Health Promotion Center Department of Public HealthMedical CollegeQinghai UniversityXiningQinghai 810061China Alive&Thrive East Asia Pacific FHI 360Hanoi 11022Vietnam

Objective:We examined the association between body mass index(BMI)and body fat percentage(BF%)measured by Dual-energy X-ray absorptiometry(DxA)among adults and children in China.Methods:We searched four databases-PubMed,China National Knowledge Infrastructure,Wanfang,and Vip for studies published in the past 22 years.Meta-analysis was conducted using random-or fixed-effect models.Results:In total of 21 studies met inclusion criteria and were included in review,and 17 ot them in meta-analysis.They were conducted across China.Their sample size ranged from 62 to 5726,and participants'age ranged from 6-80 years.Meta-analysis revealed strong associations between BMI and BF% measured by DxA in adults(pooled r=0.71,95% CI:0.66 to 0.74)and children(pooled r=0.60,95% CI:0.52 to 0.68).The association was stronger in Northern China than in East China in children(β=-0.40,95%CI:-0.65 to-0.14)and in Central China in adults(β=-0.25;95% CI:-0.51 to-0.01).Urban children's BMI was strongly associated with BF%than rural(β=0.19;95%CI:0.04 to 0.35),whereas it was stronger in adults living in rural than in urban(β=-0.35;95% CI:-0.66 to-0.05).Conclusions:BMI was strongly associated with BF%measured by DxA,and the association in children and adults in China varied by residence and region.

关键词： Body mass index Dual-energy X-ray absorptiometry Body adiposity Children Adults China

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Reduced upper limb lean mass on dual energy x-ray absorptiometry predicts adverse outcomes in male liver transplant recipients

引用

World Journal of Transplantation 2022年第6期12卷 120-130页

作者： Penelope Hey Rudolf Hoermann Paul Gow Timothy P Hanrahan Adam G Testro Ross Apostolov Marie Sinclair Liver Transplant Unit Austin HealthHeidelberg 3084Australia Department of Medicine University of MelbourneMelbourne 3052Australia

BACKGROUND Pre-transplant muscle wasting measured by computed tomography has been associated with adverse clinical outcomes after liver transplantation including increased rates of sepsis and hospitalisation days.Upper limb lean mass(LM)measured by Dual-energy X-ray absorptiometry(DExA)was recently identified as a novel predictor of sarcopenia-associated mortality in men waitlisted for transplantation.AIM To investigate the use of DExA LM in predicting gender-stratified early posttransplant outcomes.METHODS Liver transplant recipients who underwent pre-transplant DExA body composition imaging between 2002 and 2017 were included.Endpoints included posttransplant mortality and graft failure,bacterial infections,acute cellular rejection(ACR)and intensive care and total hospital length of stay.RESULTS Four hundred and sixty-nine patients met inclusion criteria of which 338 were male(72%).Median age was 55.0 years(interquartile range 47.4,59.7)and model for end-stage liver disease(MELD)score 16.Median time from assessment to transplantation was 7 mo(3.5,12).Upper limb LM was inversely associated with bacterial infections at 180 d post-transplant(hazard ratio=0.42;95%confidence interval:0.20-0.89;P=0.024)in males only.There was a negative correlation between upper limb LM and intensive care(τb=-0.090,P=0.015)and total hospital length of stay(τb=-0.10,P=0.0078)in men.In women,neither MELD nor body composition parameters were associated with post-transplant adverse outcomes or increased length of stay.Body composition parameters,MELD and age were not associated with 90-d mortality or graft failure in either gender.There were no significant predictors of early ACR.CONCLUSION Sarcopenia is an independent and potentially modifiable predictor of increased post-transplant bacterial infections and hospital length of stay in men with cirrhosis.DExA upper limb LM provides a novel measure of muscle wasting that has prognostic value in this cohort.The lack of association in women requires further investigation.

关键词： Dual-energy X-ray absorptiometry Sarcopenia Body composition Liver transplantation Survival

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Deep Learning in DxA Image Segmentation

引用

Computers, Materials & Continua 2021年第3期66卷 2587-2598页

作者： Dildar Hussain Rizwan Ali Naqvi Woong-Kee Loh Jooyoung Lee School of Computational Science Korea Institute for Advanced Study(KIAS)85 HoegiroDongdaemun-guSeoul02455South Korea Department of Unmanned Vehicle Engineering Sejong University209Neungdong-roGwangjin-guSeoul05006South Korea Department of Software Gachon UniversitySeongnam13120South Korea

Many existing techniques to acquire Dual-energy X-ray absorptiometry(DxA)images are unable to accurately distinguish between bone and soft tissue.For the most part,this failure stems from bone shape variability,noise and low contrast in DxA images,inconsistent x-ray beam penetration producing shadowing effects,and person-to-person variations.This work explores the feasibility of using state-of-the-art deep learning semantic segmentation models,fully convolutional networks(FCNs),SegNet,and U-Net to distinguish femur bone from soft tissue.We investigated the performance of deep learning algorithms with reference to some of our previously applied conventional image segmentation techniques(i.e.,a decision-tree-based method using a pixel label decision tree[PLDT]and another method using Otsu’s thresholding)for femur DxA images,and we measured accuracy based on the average Jaccard index,sensitivity,and specificity.Deep learning models using SegNet,U-Net,and an FCN achieved average segmentation accuracies of 95.8%,95.1%,and 97.6%,respectively,compared to PLDT(91.4%)and Otsu’s thresholding(72.6%).Thus we conclude that an FCN outperforms other deep learning and conventional techniques when segmenting femur bone from soft tissue in DxA images.Accurate femur segmentation improves bone mineral density computation,which in turn enhances the diagnosing of osteoporosis.

关键词： Segmentation deep learning osteoporosis Dual-energy X-ray absorptiometry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Differences in body composition measurements assessed by air displacement plethysmography and dual-energy xray absorptiometry in young and middle-aged Chinese adults

Differences in body composition measurements assessed by air...

引用

中国营养学会第十五届全国营养科学大会

作者： Yiwen Huang Hongbo Dong Hong Cheng xinying Shan xiaoran Yu xianghui xie Jie Mi 国家儿童医学中心首都医科大学附属北京儿童医院儿童慢病管理中心首都儿科研究所

Dual-energy X-ray absorptiometry(DxA) and air displacement plethysmography(ADP) are two widely used methods for body composition analysis(BCA). However, little is known about the discrepancies in the results of BCA obtained from the two methods in Chinese population. This study aimed to compare the measurement differences between DxA and ADP in young and middle-aged Chinese adults, and to explore the influential factors of this difference. Methods A total of 186 healthy volunteers(male(51.1%) vs. female(49.9%)) who aged 18-56 years old with body mass index(BMI) of 15.9-35.9 kg/m2 were enrolled. Fat mass(FM), fat mass percentage(FMP), and fat-free mass(FFM) were analyzed by both DxA and ADP within 1 hour. Results In general, all the BCA measures of DxA and ADP were highly correlated(intraclass correlation coefficient ICC>0.80, PxA than ADP. Moreover, the average difference in FM and FMP as referred to ADP changed from positive in underweight group to negative in obesity group, and vice versa for FFM. At the individual level, the proportion of relative errors for FM and FMP within ±15% was less than 10% in underweight subjects and over 75% in those with obesity. For FFM, all underweight subjects had a relative error within 15%, and the proportion was 90.5% for obese males and 85.0% for obese females. Conclusion The differences in BCA results measured by DxA and ADP were strongly influenced by BMI status at both population and individual levels. Caution should be especially taken when interchanging body fat results measured by the two methods in underweight and obese subjects.

关键词： Body composition analysis Dual-energy X-ray absorptiometry Air displacement plethysmography Chinese adults Comparative study

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Nutritional assessment in cirrhotic patients with hepatic encephalopathy

引用

World Journal of Hepatology 2015年第30期7卷 2940-2954页

作者： Fernando Gomes Romeiro Lais Augusti Gastroenterology Division Department of Internal Medicine-Botucatu Medical SchoolUNESP-Univ Estadual PaulistaBotucatu 18608-917Sao PauloBrazil

Hepatic encephalopathy(HE) is one of the worst complications of liver disease and can be greatly influenced by nutritional status. Ammonia metabolism, inflammation and muscle wasting are relevant processes in HE pathophysiology. Malnutrition worsens the prognosis in HE, requiring early assessment of nutritional status of these patients. Body composition changes induced by liver disease and limitations superimposed by HE hamper the proper accomplishment of exams in this population, but evidence is growing that assessment of muscle mass and muscle function is mandatory due to the role of skeletal muscles in ammonia metabolism. In this review, we present the pathophysiological aspects involved in HE to support further discussion about advantages and drawbacks of some methods for evaluating the nutritional status of cirrhotic patients with HE, focusing on body composition.

关键词： Hepatic encephalopathy Liver cirrhosis Malnutrition Anthropometry Muscle strength Electric impedance Nutrition assessment Dual-energy X-ray absorptiometry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：