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3D-printed gelatin methacrylate (GelMA)/ silanated silica scaffold assisted by two-stage cooling system for hard tissue regeneration

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Regenerative Biomaterials 2021年第2期8卷 50-63页

作者： Eunjeong Choi Dongyun Kim Donggu Kang Gi Hoon Yang Bongsu Jung MyungGu Yeo Min-Jeong Park SangHyun An KyoungHo Lee Jun Sik Kim Jong Chul Kim Woonhyeok Jeong Hye Hyun Yoo Hojun Jeon Research Institute of Additive Manufacturing and Regenerative Medicine Baobab Healthcare Inc55 Hanyangdaehak-RoAnsanGyeonggi-do 15588South Korea Department of Mechanical Engineering Korea Polytechnic UniversitySangidaehak-roSiheungGyeonggi-do 15073South Korea Medical Device Development Center Daegu-Gyeongbuk Medical Innovation Foundation(DGMIF)80Cheombok-roDong-guDaegu 41061South Korea Laboratory Animal Center Daegu-Gyeongbuk Medical Innovation Foundation(DGMIF)80 Cheombok-roDong-guDaegu 41061South Korea Department of Plastic and Reconstructive Surgery Dongsan Medical CenterKeimyung University College of Medicine1035 Dalgubeol-daeroDalseo-guDaegu 42601South Korea Institute of Pharmaceutical Science and Technology College of PharmacyHanyang University55 Hanyangdaehak-RoAnsanGyeonggi-Do 15588South Korea

Among many biomaterials,gelatin methacrylate(GelMA),a photocurable protein,has been widely used in 3D bioprinting process owing to its excellent cellular responses,biocompatibility and ***,GelMA still shows a low processability due to the severe temperature dependence of *** overcome this obstacle,we propose a two-stage temperature control system to effectively control the viscosity of *** optimize the process conditions,we evaluated the temperature of the cooling system(jacket and stage).Using the established system,three GelMA scaffolds were fabricated in which different concentrations(0,3 and 10 wt%)of silanated silica particles were *** evaluate the performances of the prepared scaffolds suitable for hard tissue regeneration,we analyzed the physical(viscoelasticity,surface roughness,compressive modulus and wettability)and biological(human mesenchymal stem cells growth,western blotting and osteogenic differentiation)***,the composite scaffold with greater silica contents(10 wt%)showed enhanced physical and biological performances including mechanical strength,cell initial attachment,cell proliferation and osteogenic differentiation compared with those of the *** results indicate that the GelMA/silanated silica composite scaffold can be potentially used for hard tissue regeneration.

关键词： 3D bioprinting gelatin methacrylate silanated silica cooling system human mesenchymal stem cells

Research and application of methods for effectiveness evaluation of mine cooling system

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International Journal of Mining Science and Technology 2015年第4期25卷 649-654页

作者： Guo Pingye Wang Yanwei Duan Mengmeng Pang Dongyang Li Nan State Key Laboratory of Geomechanics and Deep Underground Engineering School of Mechanics and Civil Engineering China University of Mining and Technology China Institute of Water Resources and Hydropower Research

Regarding the complexity and inconsistency of results in existing evaluation methods of mine cooling system, this paper clarifies the advantages, disadvantages and application of various mine cooling sys- tems through principle analysis, and divides all the cooling systems into air-cooling, ice-cooling and water-cooling according to the transportation of cold energy. On this basis, the paper proposes a simple and efficient evaluation method for mine cooling system. The first index of this method is the air temper- ature at point C which is 15 m away from the return wind corner at working face. A cooling system will be judged ineligible if the air temperature at point C is above 30 ℃ during operation, because in this case, the combustible gases in coal will sharply overflow, inducing gas incidents. Based on the preliminary judg- ment of the first index, another two evaluation indexes are proposed based on the cooling ability and dehumidification of an airflow volume of 1000 m3/min at point C to evaluate the investment and opera- tion cost of mine cooling system. This evaluation method has already been successfully applied in the cooling system design of Zhangshuanglou coal mine.

关键词： cooling system Effectiveness Evaluation Index system

New Type Regulating Valve Applied in cooling system of Blast Furnace

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Journal of Iron and Steel Research International 2004年第2期11卷 1-3页

作者： HE Sheng-ping ZOU De-yu XU Gang LU De-chang Chongqing University Chongqing Iron and Steel Co

A new type regulating valve with the cooling mode of constant temperature difference water supply, temperature difference self operated regulating valve, was introduced into blast furnace cooling system to overcome shortcomings of the cooling mode of constant flow rate water supply. The results show that the temperature difference between inlet and outlet water of cooling wall can be decreased greatly and steadily, and the water supply for blast furnace cooling can be reduced considerably.

关键词： blast furnace cooling system self operated regulating valve

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Modeling and Simulation of Truck Engine cooling system for Onboard Diagnosis

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Journal of Donghua University(English Edition) 2004年第4期21卷 66-72页

作者：朱正礼张建武包继华 School of Mechanical Engineering Shanghai Jiaotong University Shanghai 200030

A cooling system model of a selected internal combustion engine has been built for onboard diagnosis. The model uses driving cycle data available within the production Engine Control Module (ECM): vehicle speed, engine speed, and fuel flow rate for the given ambient temperature and pressure, etc. Based on the conservation laws for heat transfer and mass flow process, the mathematical descriptions for the components involved in the cooling circuit are obtained and all the components are integrated into a model on Matlab/Simulink platform. The model can simulate the characteristics of thermostat (e.g. time-lag, hysteresis effect). The changes of coolant temperature, heat transfer flow rate, and pressure at individual component site are also shown.

关键词： cooling system Truck engine Simulation Model Matlab/Simulink.

Optimization of the cooling system of Electric Vehicle Batteries

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Fluid Dynamics & Materials Processing 2022年第3期18卷 835-850页

作者： A.Heri Iswanto Iwan Harsono Alim Al Ayub Ahmed Sergushina Elena Sergeevna Stepan Krasnikov Rustem Zalilov John William Grimaldo Guerrero Liliya N.Latipova Safa Kareem Hachim Public Health Department Faculty of Health ScienceUniversity of Pembangunan Nasional Veteran JakartaJakarta16426Indonesia Universitas Mataram West Nusa Tenggara83116Indonesia School of Accounting Jiujiang UniversityJiujiang330300China National Research Ogarev Mordovia State University Saransk430005Russia Russian Technological University Moscow119454Russian Nosov Magnitogorsk State Technical University Magnitogorsk455000Russian Departamento de Energía Universidad de la CostaBarranquilla080002Colombia Kazan Federal University Kazan628400Russia College of Technical Engineering The Islamic UniversityNajaf54001Iraq

The most important components of electrical vehicles are the battery and the related cooling *** subsystems play a major role in determining the overall electric vehicle *** this study,a novel cooling system with fluid in the battery cell is proposed,by which the energy storage system can be optimized through control of the temperature of the batteries.A sensitivity analysis is conducted considering the maximum temperature,the heat rate,the coolant temperature,and the geometry of the *** numerical simulations show that the parameters for the trapezoidal compartment have an impact on the thermal performance of *** optimal geometry is proposed *** is concluded that for high values of Reynolds number for which the flow becomes turbulent,a decrease in the battery temperature can be obtained thereby avoiding thermal stresses.

关键词： Thermal flow batteries geometry cavity cooling system

Simulation Analysis of New Energy Vehicle Engine cooling system Based on K-E Turbulent Flow Mathematical Model

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Energy Engineering 2023年第10期120卷 2325-2342页

作者： Hongyu Mu Yinyan Wang Chuanlei Yang Hong Teng Xingtian Zhao Hongquan Lu Dechun Wang Shiyang Hao Xiaolong Zhang Yan Jin College of Power and Energy Engineering Harbin Engineering UniversityHarbin150001China Extended Range Power system Research Institute Harbin Dongan Auto Engine Co.Ltd.Harbin150000China

New energy vehicles have better clean and environmental protection characteristics than traditional fuel *** new energy engine cooling technology is critical in the design of new energy *** paper used oneand three-way joint simulation methods to simulate the refrigeration system of new energy ***,a k-εturbulent flow model for the cooling pump flow field is established based on the principle of computational fluid ***,the CFD commercial fluid analysis software FLUENT is used to simulate the flow field of the cooling pump under different inlet flow *** paper proposes an optimization scheme for new energy vehicle engines’“boiling”phenomenon under high temperatures and long-time climbing *** simulation results show that changing the radiator’s structure and adjusting the thermostat’s parameters can solve the problem of a“boiling pot.”The optimized new energy vehicle engine can maintain a better operating temperature *** algorithm model can reference each cryogenic system component hardware selection and control strategy in the new energy vehicle’s engine.

关键词： New energy vehicle new energy vehicle engine k-ε turbulent flow mathematical model cooling system PID control

cooling system for China’s 35 kV/2.2kA/1.2 km high-temperature superconducting cable achieves two-year successful operation

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Superconductivity 2024年第2期10卷 46-48页

作者： Yunwu Han Xihua Zong Wei Xie Shanghai International Superconducting Technology Co.Ltd. ShanghaiChina State Grid Shanghai Municipal Electric Power Company ShanghaiChina

In December 2021,a 1.2 km high-temperature superconducting(HTS)cable,Xuhui HTS Cable Project,was completed and installed in Xuhui district,Shanghai,China.A cooling system with three refrigerators and two liquid nitrogen(LN2)pumps was developed for this km-class ***,this cooling system has worked successfully for two years without *** is a great progress for km-class HTS power cable technique,which is validating the reliability and commercial value of HTS power transmission.

关键词： cooling system km-class HTS Cable HTS power transmission

Study on Effects of Diesel Engine cooling system Parameters on Water Temperature

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Defence Technology（防务技术） 2011年第3期7卷 129-134页

作者：骆清国冯建涛刘国夫桂勇 Department of Mechanical Engineering Academy of Armored Force Engineering Department of Vehicular Engineering Armored Force Technology Institute

A simulation model for a certain diesel engine cooling system is set up by using GT-COOL. The backwater temperature response in different operating conditions is simulated numerically. The effects of single or multiple system parameters on the water temperature are analyzed. The results show that, changing different single parameters, the time taken for the steady backwater temperature is different, but relatively short;and if multiple parameters are changed, the time will be longer. Referred to the thermal balance test, the simulation results are validated and provide a basis for the intelligent control of the cooling system.

关键词： power machinery engineering diesel engine cooling system transient response simulation

Simulation and experimental study on hydraulic driving fan cooling system for construction machinery working on plateau

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Journal of Chongqing University 2009年第3期8卷 201-208页

作者：李毅 Material College Huazhong University of Science and Technology Guangdong Dahua Rensheng Science and Technology Co. Ltd.

Overheating of the engine, the transmission and the hydraulic device is a problem when the construction machinery works on plateau. To solve this problem, we proposed an electro-controlled hydraulic driving fan cooling system (ECHDFCS). The system was applied to a 50-wheel loader. We carried out the coolant temperature simulation using fluid modeling software FLOWMASTER, followed by laboratory experiments and road tests. The results show that ECHDFCS can adjust the cooling capability of the system automatically based on machine heat dissipation requirements. The coolant temperature is consequently remained within an appropriate range. The simulation results are consistent with the experiment results when the experiment is performed on the plain, but are different from the road tests in some investigated parameters on the plateau.

关键词： construction machinery hydraulic cooling system simulation plateau overheating