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Bilateral retrocorneal hyaline scrolls secondary to asymptomatic congenital syphilis: A case report

World Journal of Clinical Cases 2021年第10期9卷 2274-2280页

作者： Yu-Qi Jin Yong-Ping Hu Qi Dai Shuang-Qing Wu Department of Ophthalmology Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006Zhejiang ProvinceChina The Center of Cornea and Refraction The Eye Hospital of Wenzhou Medical UniversityHangzhou 325027Zhejiang ProvinceChina Department of Ophthalmology Zhejiang Provincial Integrated Chinese and Western Medicine HospitalHangzhou 310003Zhejiang ProvinceChina

BACKGROUND Retrocorneal hyaline scrolls are a rare *** report a case of bilateral retrocorneal hyaline scrolls that were likely induced by asymptomatic congenital *** SUMMARY A 71-year-old woman presented with blurred vision due to ***-lamp microscopy revealed bilateral hyaline scrolls with a dichotomous branching pattern extending to the anterior chamber or rods attaching to the rough posterior surface of the *** patient was positive for syphilis-specific antibodies,with no ocular or systemic evidence of congenital or acquired *** cataract,retrocorneal scroll,and corneal endothelial gutta were *** scroll of the right eye was removed during cataract surgery and further observed using hematoxylin–eosin staining and scanning electron *** cornea of the right eye remained transparent,and the residual scroll seemed stable,however,the corneal endothelial density declined at 13 mo after *** vivo confocal microscopy revealed coalescence of corneal guttae at the level of the corneal endothelium or adhesion to the posterior surface of the endothelium,with enlarged endothelial cells in both *** keratocytes in the stroma and a highly reflective acellular structure at the level of the Descemet’s membrane were *** removed scroll had a cartilage-like hardness and a circularly arranged fiber-like acellular *** Occult congenital syphilis could induce corneal endothelial gutta and theformation of retrocorneal scrolls without other signs of ocular syphilis.

关键词： Scroll Corneal endothelium congenital syphilis Syphilitic interstitial keratitis In vivo confocal microscopy Case report

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Adult female syphilis prevalence,congenital syphilis case incidence and adverse birth outcomes,Mongolia 2000e2016:Estimates using the Spectrum STI tool

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Infectious Disease Modelling 2018年第1期3卷 13-22页

作者： Erdenetungalag Enkhbat Eline L.Korenromp Jugderjav Badrakh Setsen Zayasaikhan Purevsuren Baya Enkhjargal Orgiokhuu Narantuya Jadambaa Sergelen Munkhbaatar Delgermaa Khishigjargal Narantuya Khad Guy Mahiane Naoko Ishikawa Davaalkham Jagdagsuren Melanie M.Taylor Mongolia National Centre for Communicable Disease AIDS/STI Surveillance and Research DepartmentUlaanbaatar210648Bayanzurkh DistrictNam-Yan-Ju StreetMongolia Avenir Health GenevaSwitzerland1 route de Morillons/150 Route de Ferney(WCCOffice 164)PO Box 2100CH-1211 Geneva 2Switzerland World Health Organization Post Box 663Ulaanbaatar-13Mongolia Mongolia Global Fund Supported Project on AIDS and TB Peace Avenue 13/3Sukhbaatar DistrictUlaanbaatarMongolia Mongolia Center for Health Development Enkhtaivan Street-13bSukhbaatar DistrictUlaanbaatarMongolia Avenir Health 655 Winding Brook DriveGlastonburyCTCT-06033USA World Health Organization Western Pacific Regional OfficePO Box 2932(United Nations Avenue)1000 ManilaPhilippines World Health Organization Department of Reproductive Health and Research8 Avenue Appia(L152)1211 GenevaSwitzerland Centers for Disease Control and Prevention Atlanta GAUSA

Introduction:Mongolia's health ministry prioritizes control of Sexually Transmitted Infections,including syphilis screening and treatment in antenatal care(ANC).Methods:Adult syphilis prevalence trends were fitted using the Spectrum-STI estimation tool,using data from ANC surveys and routine screening over *** were combined with programmatic data to estimate numbers of treated and untreated pregnant women with syphilis and associated incidence congenital syphilis(CS)and CS-attributable adverse birth outcomes(ABO),which we compared with CS case ***:syphilis prevalence in pregnant women was estimated at 1.7%in 2000 and 3.0%in *** estimated 652 CS cases,of which 410 ABO,in *** larger,annually increasing numbers of CS cases and ABO were estimated to have been prevented:1654 cases,of which 789 ABO in 2016thanks to increasing coverages of ANC(99%in 2016),ANC-based screening(97%in 2016)and treatment of women diagnosed(81%in 2016).The 42 CS cases reported nationally over 2016(liveborn infants only)represented 27%of liveborn infants with clinical CS,but only 7%of estimated CS cases among women found syphilis-infected in ANC,and 6%of all estimated CS cases including those born to women with undiagnosed ***/Conclusion:Mongolia's ANC-based syphilis screening program is reducing CS,but maternal prevalence remains *** eliminate CS(target:syphilis screening and prevention programs.

关键词： syphilis congenital syphilis Surveillance Screening Antenatal care Epidemiological modelling

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