Adult female syphilis prevalence,congenital syphilis case incidence and adverse birth outcomes,Mongolia 2000e2016:Estimates using the Spectrum STI tool
作者机构：Mongolia National Centre for Communicable DiseaseAIDS/STI Surveillance and Research DepartmentUlaanbaatar210648Bayanzurkh DistrictNam-Yan-Ju StreetMongolia Avenir HealthGenevaSwitzerland1 route de Morillons/150 Route de Ferney(WCCOffice 164)PO Box 2100CH-1211 Geneva 2Switzerland World Health OrganizationPost Box 663Ulaanbaatar-13Mongolia Mongolia Global Fund Supported Project on AIDS and TBPeace Avenue 13/3Sukhbaatar DistrictUlaanbaatarMongolia Mongolia Center for Health DevelopmentEnkhtaivan Street-13bSukhbaatar DistrictUlaanbaatarMongolia Avenir Health655 Winding Brook DriveGlastonburyCTCT-06033USA World Health OrganizationWestern Pacific Regional OfficePO Box 2932(United Nations Avenue)1000 ManilaPhilippines World Health OrganizationDepartment of Reproductive Health and Research8 Avenue Appia(L152)1211 GenevaSwitzerland Centers for Disease Control and PreventionAtlanta GAUSA
出 版 物：《Infectious Disease Modelling》 (传染病建模（英文）)
年 卷 期：2018年第3卷第1期
页 面：13-22页
学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学]
基 金：The project was funded by the World Health Organization Department of Reproductive Health and Research
主 题：Syphilis Congenital syphilis Surveillance Screening Antenatal care Epidemiological modelling
摘 要：Introduction:Mongolia s health ministry prioritizes control of Sexually Transmitted Infections,including syphilis screening and treatment in antenatal care(ANC).Methods:Adult syphilis prevalence trends were fitted using the Spectrum-STI estimation tool,using data from ANC surveys and routine screening over *** were combined with programmatic data to estimate numbers of treated and untreated pregnant women with syphilis and associated incidence congenital syphilis(CS)and CS-attributable adverse birth outcomes(ABO),which we compared with CS case ***:Syphilis prevalence in pregnant women was estimated at 1.7%in 2000 and 3.0%in *** estimated 652 CS cases,of which 410 ABO,in *** larger,annually increasing numbers of CS cases and ABO were estimated to have been prevented:1654 cases,of which 789 ABO in 2016thanks to increasing coverages of ANC(99%in 2016),ANC-based screening(97%in 2016)and treatment of women diagnosed(81%in 2016).The 42 CS cases reported nationally over 2016(liveborn infants only)represented 27%of liveborn infants with clinical CS,but only 7%of estimated CS cases among women found syphilis-infected in ANC,and 6%of all estimated CS cases including those born to women with undiagnosed ***/Conclusion:Mongolia s ANC-based syphilis screening program is reducing CS,but maternal prevalence remains *** eliminate CS(target:50 cases per 100,000 live births),Mongolia should strengthen ANC services,limiting losses during referral for treatment,and under-diagnosis of CS including still-births and neonatal deaths,and expand syphilis screening and prevention programs.
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