检索结果-南通市图书馆

Journal of Clinical and Nursing Research 2024年第8期8卷 237-242页

作者： Tingting Wang Cui Xia Xuzhou City Hospital of Traditional Chinese Medicine Xuzhou 221000Jiangsu ProvinceChina

Objective:To evaluate the impact of predictive nursing on the care of acute myocardial infarction(AMI)patients in the Coronary Care Unit(CCU)after interventional ***:From September 2021 to September 2023,84 AMI patients admitted to the CCU were randomly divided into two groups:the experimental group(42 patients)received predictive nursing,and the reference group(42 patients)received conventional *** function and clinical outcomes were compared between the ***:Before nursing,there was no difference in cardiac function between the two groups(P>0.05).After nursing,the cardiac function of the experimental group was better than that of the reference group(P0.05).After nursing,the psychological scores of the experimental group were lower than those of the reference group(Pcardiac function and clinical outcomes of AMI patients after interventional therapy and can also regulate patients’negative psychological states.

关键词： Predictive nursing CCU Acute myocardial infarction Interventional therapy cardiac function

The Impact of cardiac Pacing Site on Patient's cardiac function and Psychological State

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Expert Review of Chinese Medical

Expert Review of Chinese Medical 2024年第2期2卷 18-22页

作者： Haiyang Xiao Liang Sun Cardiology Department of Hefei Eighth People's Hospital Medical College of Jinzhou Medical University

With the widespread application of artificial permanent pacemakers in clinical practice,there have been new changes in the indications for pacemaker *** current clinical indications include high atrioventricular block,sick sinus syndrome,cardiac resynchronization therapy for heart failure,and implantation of cardioverter defibrillators for ventricular *** implantation of a pacemaker can improve the quality of life and prognosis of patients with *** the past,permanent pacemaker implantation was performed in clinical practice,and the right ventricular pacing electrode was often fixed at the apex of the right ventricle,which belongs to non physiological *** long-term clinical follow-up,it was found that apex pacing can easily cause abnormal depolarization of the left ventricle,asynchronous contraction of the myocardium,and ultimately lead to myocardial fibrosis,which has adverse effects on the patient's cardiac function and psychological *** recent years,Scholars have found that pacing in the right ventricular outflow tract septum is closer to the atrioventricular node and closer to the His bundle Purkinje *** pacing impulse almost simultaneously expands towards both ventricles,closer to the physiological pacing state,thereby reducing the occurrence of cardiovascular events in *** article explores the impact of pacing in different parts of the heart on the cardiac function and psychological state of patients based on clinical data from the past three years.

关键词： pacing site cardiac function psychological state

Effectiveness of Atorvastatin Combined with Trimetazidine in the Treatment of Coronary Heart Disease in the Elderly and Their Effect on cardiac function

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Nursing Research 2024年第5期8卷 266-270页

作者： Fan Yang People’s Liberation Army Dalian 10th Separation Cadre Recreation Center Liaoning Military RegionDalian 116000LiaoningChina

Objective:To analyze the effect of atorvastatin combined with trimetazidine in the treatment of elderly coronary artery disease and the effect on patients’cardiac ***:60 cases of elderly coronary artery disease patients were divided into 2 groups by randomization method,and all of them received conventional symptomatic treatment,while atorvastatin was added to the control group and trimetazidine was combined with atorvastatin in the observation group,and the clinical indexes were ***:After treatment,the angina attack,cardiac function indexes,and inflammatory factor levels of the observation group were better than those of the control group(P0.05).Conclusion:Combined treatment of coronary heart disease in the elderly with atorvastatin and trimetazidine can positively reduce angina symptoms,improve cardiac function,and reduce inflammatory reactions,and the effect is definite.

关键词： Coronary heart disease in the elderly Atorvastatin Trimetazidine cardiac function

Effects of Continuous Precision Nursing Model on Knowledge, Attitudes, and Practices (KAP) Behavior and cardiac function in Patients after Percutaneous Coronary Angiography and Stent Implantation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Nursing Research 2024年第3期8卷 1-6页

作者： Cuiying Han Xuzhou City Hospital of TCM Xuzhou 221000China

Objective:To explore the impact of a continuous precision nursing model on patients’Knowledge,Attitudes,and Practices(KAP)and cardiac function during the nursing process of patients undergoing percutaneous coronary angiography and stent ***:Ninety patients who underwent percutaneous coronary angiography and stent implantation in our hospital from April 2022 to April 2023 were selected and randomly divided into the control group(45 cases),in which routine nursing support was carried out during the treatment process,and the observation group(45 cases),in which continuous precision nursing model was carried out during the treatment *** were made between the two groups of patients on their KAP,cardiac function,and quality of life during ***:There was no difference in the left ventricular ejection fraction(LVEF),cardiac output(CO),and cardiac index(CI)levels before *** the intervention,the levels of cardiac function in the observation group were higher than those of the control group(Pcardiac function,and KAP,and promoted recovery.

关键词： Continuous precision nursing model Percutaneous coronary angiography Stent implantation Knowledge,attitudes,and practices(KAP) cardiac function

Allicin Improves cardiac function by Protecting against Apoptosis in Rat Model of Myocardial Infarction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2017年第8期23卷 589-597页

作者： MA Li-na LI Lian-da LI Shao-chun HAO Xin-mei ZHANG Jin-yan HE Ping LI Yi-kui Graduate School Beijing University of Chinese Medicine Laboratory of Academician LI Lian-da Xiyuan HospitalChina Academy of Chinese Medical Sciences School of Basic Medical Sciences Hebei University

Objective：To study the effects of allicin on cardiac function and underlying mechanism in rat model of myocardial infarction（MI）.Methods：Ninety-four Wistar rats were randomly assigned to 6 groups（n=14–16 per group）：sham control group[underwent thoracotomy without left anterior descending（LAD）occlusion and only received an injection of the same amount of citrate buffer],MI control group（subjected to LAD occlusion and only received an injection of same amount of citrate buffer）,positive control group（subjected to LAD occlusion and received an injection of diltiazem hydrochloride at the dose of 1.5 mg/kg）,and MI＋allicin groups（subjected to LAD occlusion and received an injection of allicin at the doses of 1.2,1.8,and 3.6 mg/kg）.All of the drugs were administered intraperitoneally daily for 21 *** infarct area was measured by myocardial ***-eosin staining was used to observe the pathological *** function parameters were assessed by *** myocardial apoptotic index was estimated by terminal deoxynucleotidyl transferase-mediated d UTP nick-end labeling *** expression of Bax and Bcl-2 were detected by quantificational real-time polymerase chain reaction and Western ***：Treatment with allicin could attenuate the myocardial infarct area（P〈0.05）and relieve the changes of the *** left ventricular anterior wall diastolic and systolic thicknesses were increased in the allicin-treated groups（P〈0.05）,while there was no significant difference in the left ventricular posterior wall diastolic and systolic thickness（P〉0.05）.The left ventricular internal diameter in systole,ejection fraction,fractional shortening,and stroke volume were dramatically elevated in allicin-treated rats（P〈0.05）.Allicin dose-dependently reduced creatine kinase and lactate dehydrogenase levels（P〈0.05）.The myocardial apoptotic index was also markedly lowered,and Bax expression was significantly decreased,whereas Bcl-2 expression exhib

关键词： allicin myocardial infarction cardiac function apoptosis Bcl-2/Bax

Nicorandil pretreatment inhibits myocardial apoptosis and improves cardiac function after coronary microembolization in rats

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2018年第9期15卷 591-597页

作者： Wen-Kai HE Qiang SU Jiao-Bao LIANG Xian-Tao WANG Yu-Han SUN Lang LI Department of Cardiology the First Affiliated Hospital of Guangxi Medical University Nanning China

Background Nicorandil （NIC） is a vasodilatory drug used to treat angina. However, its efficacy of cardioprotection in coronary mi- croembolization （CME） is largely unknown. This study was undertaken to determine whether nicorandil pretreatment could attenuate myo- cardial apoptosis and improve cardiac function after CME in rats. Methods Forty-five rats were randomly divided into a Sham group, a CME group and a CME ＋ NIC （NIC） group （n = 15 per group）. CME was established by injecting plastic microspheres （42 pm in diameter） into the left ventricle of the rats in all of the groups except the Sham group. The NIC group received nicorandil at 3 mg/kg per day for seven days before the operation. cardiac fimction was assessed by echocardiography, the expression levels of cleaved caspase-9/8/3 were detected by Western blot, microinfarction area was measured by haematoxylin-basic fuchsin picric acid staining, and myocardial apoptosis was de- tected by TUNEL staining. Results Compared to that in the Sham group, cardiac fimction in the CME group was significantly decreased （P 〈 0.05）. However, compared to the CME group, the NIC group showed improved cardiac function （P 〈 0.05）. The expression levels of cleaved caspase-9/8/3 protein and myocardial apoptosis were dramatically increased in the CME group compared to those in the Sham group （P 〈 0.05）, while the NIC pretreatment group had significantly decreased expression levels of cleaved caspase-9/8/3 protein as well as a de- creased apoptotic rate （P 〈 0.05）. Conclusions NIC pretreatment inhibited CME-induced myocardial apoptosis and improved cardiac func- tion through blockade of the mitochondrial and death receptor-mediated apoptotic pathways.

关键词： Apoptosis Coronary microembolization cardiac function Nicorandil

An injectable conductive hydrogel restores electrical transmission at myocardial infarct site to preserve cardiac function and enhance repair

在线全文

学校读者我要写书评

暂无评论

生物活性材料(英文) 2023年第2期20卷 339-354页

作者： Linghong Zhang Tao Li Yan Yu Kun Shi Zhongwu Bei Yongjun Qian Zhiyong Qian State Key Laboratory of Biotherapy State Key Laboratory and Collaborative Innovation Center of BiotherapyWest China HospitalSichuan UniversityChengdu610041SichuanPR China Department of Cardiovascular Surgery West China HospitalSichuan UniversityChengdu610041SichuanPR China

Myocardial infarction(MI)leads to massive cardiomyocyte death and deposition of collagen *** fibrous tissue disrupts electrical signaling in the myocardium,leading to cardiac systolic and diastolic dysfunction,as well as *** hydrogels are a promising therapeutic strategy for ***,we prepared a highly water-soluble conductive material(GP)by grafting polypyrrole(PPy)onto non-conductive *** component was added to the gel system formed by the Schiff base reaction between oxidized xanthan gum(OXG)and gelatin to construct an injectable conductive *** prepared self-healing OGGP3(3 wt%GP)hydrogel had good biocompatibility,elastic modulus,and electrical conductivity that matched the natural *** prepared biomaterials were injected into the rat myocardial scar tissue 2 days after *** found that the cardiac function of the rats treated with OGGP3 was improved,making it more difficult to induce *** electrical resistivity of myocardial fibrous tissue was reduced,and the conduction velocity of myocardial tissue was *** analysis showed reduced infarct size,increased left ventricular wall thickness,increased vessel density,and decreased inflammatory response in the infarcted *** findings clearly demonstrate that the OGGP3 hydrogel attenuates ventricular remodeling and inhibits infarct dilation,thus showing its potential for the treatment of MI.

关键词： Myocardial infarction Injectable hydrogel Conductivity cardiac function

Effects of Compound Danshen Dripping Pills on Ventricular Remodeling and cardiac function after Acute Anterior Wall ST-Segment Elevation Myocardial Infarction(CODE-AAMI):Protocol for a Randomized Placebo-Controlled Trial

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2023年第12期29卷 1059-1065页

作者： WU Yu-jie DENG Bo WANG Si-bo QIAO Rui ZHANG Xi-wen LU Yuan WANG Li GU Shun-zhong ZHANG Yu-qing LI Kai-qiao YU Zong-liang WU Li-xing ZHAO Sheng-biao ZHOU Shuang-lin YANG Yang WANG Lian-sheng Department of Cardiology the First Affiliated Hospital of Nanjing Medical UniversityNanjing(210029)China Department of Cardiology Anqing Municipal Hospital Affiliated to Anhui Medical UniversityAnqingJiangsu Province(246003)China Department of Cardiology Huai'an First People's HospitalHuai'anJiangsu Province(223300)China Department of Cardiology the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu Province(221006)China Department of Cardiology Pukou Branch of Jiangsu People's HospitalNanjing(211899)China Department of Cardiology Hai'an People's HospitalNantongJiangsu Province(226699)China Department of Cardiology the Affliated Jiangning Hospital of Nanjing Medical UniversityNanjing(211199)China Department of Cardiology Qixia District Hospital of Nanjing CityNanjing(210046)China Department of Cardiology the First People's Hospital of Kunshan Affliated to Jiangsu UniversityKunshanJiangsu Province(215300)China Department of Cardiology Nanjing Lishui District Hospital of Traditional Chinese MedicineNanjing(211299)China Department of Cardiology Nanjing Meishan HospitalNanjing(210039)China

Background:Ventricular remodeling after acute anterior wall ST-segment elevation myocardial infarction(AAMI)is an important factor in occurrence of heart failure which additionally results in poor ***,the treatment of ventricular remodeling needs to be further *** Danshen Dripping Pills(CDDP),a traditional Chinese medicine,exerts a protective effect on microcirculatory disturbance caused by ischemia-reperfusion injury and attenuates ventricular remodeling after myocardial ***:This study is designed to evaluate the efficacy and safety of CDDP in improving ventricular remodeling and cardiac function after AAMI on a larger ***:This study is a multi-center,randomized,doubleblind,placebo-controlled,parallel-group clinical *** total of 268 patients with AAMI after primary percutaneous coronary intervention(pPCI)will be randomly assigned 1:1 to the CDDP group(n=134)and control group(n=134)with a follow-up of 48 *** groups will be treated with standard therapy of ST-segment elevation myocardial infarction(STEMI),with the CDDP group administrating 20 tablets of CDDP before pPCI and 10 tablets 3 times daily after pPCI,and the control group treated with a placebo *** primary endpoint is 48-week echocardiographic outcomes including left ventricular ejection fraction(LVEF),left ventricular end-diastolic volume index(LVEDVI),and left ventricular end-systolic volume index(LVESVI).The secondary endpoint includes the change in N terminal pro-B-type natriuretic peptide(NT-proBNP)level,arrhythmias,and cardiovascular events(death,cardiac arrest,or cardiopulmonary resuscitation,rehospitalization due to heart failure or angina pectoris,deterioration of cardiac function,and stroke).Investigators and patients are both blinded to the allocated ***:This prospective study will investigate the efficacy and safety of CDDP in improving ventricular remodeling and cardiac function in patients und

关键词： Compound Danshen Dripping Pills acute anterior myocardial infarction randomized controlled trial ventricular remodeling cardiac function trial design

Qishen Taohong Granule as Adjuvant Therapy for Improving cardiac function and Quality of Life in Patients with Chronic Heart Failure:A Randomized Controlled Trial

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2022年第1期28卷 12-19页

作者： LI Xing-xing WU Yang FAN Zong-jing CUI Jie LI Dong LIN Quan ZHUANG Rui YAN Rong-kun LIN Qian LI Yan Department of Graduate School Beijing University of Chinese MedicineBeijing(100029)China Department of Cardiology Dongfang HospitalBeijing University of Chinese MedicineBeijing(100078)China Department of Cardiology Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing(100091)China Department of Cardiology Dongzhimen HospitalBeijing University of Chinese MedicineBeijing(100700)China

Objective:To confirm the improvement of cardiac function and quality of life(QoL)in patients with chronic heart failure(CHF)via Chinese medicine(CM)Qishen Taohong Granule(QTG).Methods:This study was a single-center,prospective,randomized,controlled clinical ***-six patients from 27 to 84 years old diagnosed with CHF New York Heart Association(NYHA)classⅡorⅢin stage C were enrolled and randomly assigned at a 1:1 ratio to receive QTG or trimetazidine(TMZ),in addition to their standard medications for the treatment of *** study period was 4 *** primary outcomes included cardiac function evaluated by NYHA classification and left ventricular ejection fraction(LVEF),as well as QoL evaluated by CHF Integrated Chinese and Western Medicine Survival Scale(CHFQLS).The secondary outcomes included 6-min walking test(6 MWT),CM syndrome score,symptom and sign scores and N-terminal pro-B-type natriuretic peptide level(NT-proBNP).All indices were measured at baseline and the end of the ***:At the 4-week follow-up period,the effective rate according to NYHA classification in the QTG group was better than that in the TMZ group(74.29%vs.54.29%,P0.05).The CHFQLS scores improved by 13.82±6.04 vs.7.49±2.28 in the QTG and TMZ groups,respectively(Pfunction,role limitation and vitality were significantly higher in the QTG group than in the TMZ group(15.76±7.85 vs.7.40±3.36,Pcardiac events occurred during treatment in either ***:In addition to conventional treatments,the use of QTG a

关键词： chronic heart failure Chinese medicine Qishen Taohong Granule cardiac function quality of life

Early association of electrocardiogram alteration with infarct size and cardiac function after myocardial infarction

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University Science 2004年第4期5卷 494-498页

作者：陶则伟黄元伟夏强傅军赵志宏陆贤 BRUCEI.C. DepartmentofCardiology FirstAffiliatedHospitalCollegeofMedicineZhejiangUniversityHangzhou310003China DepartmentofPhysiology CollegeofMedicineZhejiangUniversityHangzhou310006China DepartmentofPhysiology theUniversityofHongKongHongKongChina

Objective: Myocardial infarction (MI) is the main cause of heart failure, but the relationship between the extent of MI and cardiac function has not been clearly determined. The present study was undertaken to investigate early changes in the electrocardiogram associated with infarct size and cardiac function after MI. Methods: MI was induced by ligating the left anterior descending coronary artery in rats. Electrocardiograms, echocardiographs and hemodynamic parameters were assessed and myocardial infarct size was measured from mid-transverse sections stained with Masson抯 trichrome. Results: The sum of pathological Q wave amplitudes was strongly correlated with myocardial infarct size (r = 0.920, P cardiac function as assessed by left ventricular ejection fraction (r = -0.913, P cardiac function.

关键词： Electrocardiogram Myocardial infarction cardiac function