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Cardiovascular risk management in cancer survivors:Are we doing it right?

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World Journal of Clinical Oncology 2021年第3期12卷 144-149页

作者： Turab Mohammed Tarang Parekh Aakash Desai Department of Medicine University of ConnecticutFarmingtonCT 06030United States Department of Health Administration and Policy George Mason UniversityFairfaxVA 22030United States Department of Hematology and Oncology Mayo ClinicRochesterMN 55902United States

Although under-recognized,cancer survivors continue to be at an increased risk of death from cardiovascular complications post-remission or *** increased burden of cardiovascular disease results from the interplay of various *** cardiovascular risk assessment and timely intervention through a multi-disciplinary approach in these patients plays a pivotal role in the prevention of cardiovascular morbidity and *** discuss the shortcomings of using current risk prediction scores in cancer survivors and provide some insights into cardiovascular risk management relevant for primary care physicians,oncologists,and cardiologists alike.

关键词： cancer survivors Cardio-oncology Atherosclerotic cardiovascular disease risk estimator Cardiovascular disease risk Childhood cancer survivor study cancer policy

Evaluation of the Long-Term Changes in Fatigue of cancer survivors Who Received Outpatient Chemotherapy in the Area Affected by the Great East Japan Earthquake

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Open Journal of Nursing 2021年第7期11卷 566-577页

作者： Daisuke Sato Faculty of Health Sciences Komatsu University Ishikawa Japan

Objective: The aim of the study is to evaluate the long-term changes in fatigue of cancer patients receiving outpatient chemotherapy after a disaster such as the Great Earthquake. Methods: From 2012 to 2014, we measured subjective fatigue, autonomic function, and physical activity with reference to the criteria for chronic fatigue syndrome. Results: The participants were 13, 9 males (69.2%) and 4 females (30.8%). The most common cancer among the participants was lung cancer 4 patients (30.8%). In 2012, eight patients (61.6%) received anti-cancer drugs and three (23.0%) received the drug by intravenous drip and oral administration. Physical fatigue (p = 0.004), mental fatigue (p = 0.002), comprehensive fatigue (p = 0.012), and comprehensive evaluations (p = 0.032) were significantly different. Significant differences in the autonomic nervous function were observed during the three years from 2012 to 2014 (log LF [p = 0.017], log HF [p = 0.023] and log LF/HF [p = 0.039]). Similar to Subjective fatigue, Significant differences in physical activity were observed during the three years from 2012 to 2014 (DA [p = 0.042], TST [p = 0.037], SE [p = 0.018], AW [p = 0.023] and Naps [p = 0.014]). Conclusions: The participants fatigue worsened at one time, but showed improvement over time. In the event of an emergency such as a disaster, it is necessary to evaluate the physical and mental condition based on objective indicators of cancer patients receiving anti-cancer drug treatment and provide nursing support.

关键词： cancer survivors Outpatient Chemotherapy Fatigue The Great East Japan Earthquak

“I Felt Defeated. I Felt Helpless”: Social Determinants of Health Influencing the cancer survivorship of a Young Latina Mother

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Journal of cancer Therapy 2022年第7期13卷 440-449页

作者： Adriena Hernandez Clara L. Reyes Isela Garcia Rebecca L. Palacios Department of Health Promotion Sciences The University of Arizona Tucson AZ USA Department of Public Health Sciences New Mexico State University Las Cruces NM USA

Social determinants of health (SDOH) contribute to cancer disparities among young Latina women (<50 years) residing in the counties along the US-Mexico border. These SDOH are particularly burdensome to young Latina mo... 详细信息

Social determinants of health (SDOH) contribute to cancer disparities among young Latina women (cancer while they are raising school-age children. Conexiones, a culturally adapted program designed to improve mother and child adjustment to maternal cancer, was piloted with diagnosed Latina mothers residing in border counties in New Mexico and Texas. The purpose of this case analysis was to highlight the SDOH affecting a young Latina mother’s cancer survivorship in the U.S.-Mexico border region. The participant’s Conexiones education sessions were recorded, transcribed, translated to English, back translated to Spanish to establish accuracy, and inductively coded. The participant’s baseline survey indicated she was a young (cancer while raising a teenage daughter. Seventeen SDOH themes affecting the participant’s cancer experience were identified in the cancer-related emotional triggers she reported across five Conexiones sessions. These themes were organized using Yanez’s conceptual model of determinants of cancer outcomes in Hispanics (i.e., socioeconomic, healthcare, cultural context, and psychosocial). Findings provide direction for cultural adaptations of evidence-based programs.

关键词： cancer survivors Latinas Social Determinants of Health U.S.-Mexico Border

Endothelial impairment evaluation by peripheral arterial tonometry in pediatric endocrinopathies:A narrative review

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World Journal of Diabetes 2021年第6期12卷 810-826页

作者： Alberto La Valle Marco Crocco Decimo Silvio Chiarenza Mohamad Maghnie Giuseppe d'Annunzio Pediatric Clinic and Endocrinology IRCCS Istituto Giannina GasliniGenoa16147Italy Pediatric Clinic and Endocrinology IRCCS Giannina Gaslini InstituteDepartment of NeuroscienceRehabilitationOphthalmologyGeneticsMaternal and Child Health University of GenoaGenoa16147Italy

Endothelial dysfunction(ED)is characterized by an imbalance between vasodilator and vasoconstriction *** pathological conditions clinically diagnosed in childhood and adolescence are characterized by ED and increased risk for early development of microangiopathic and macroangiopathic impairment,in particular type 1 diabetes mellitus(T1DM),T2DM,obesity,metabolic syndromeand pituitary dysfunction associated to various *** recently insulin resistance following chemotherapy or radiotherapy for tumors,bone marrow transplantation for hematological malignancies(i.e.,cancer survivors),or immunosuppressive treatment for solid organ transplantation has been *** of ED by means of non-invasive techniques is the gold standard for early ED detection before clinical *** is aimed to recognize patients at risk and to avoid the development and progression of more serious *** hyperemia-peripheral artery tonometry is a noninvasive technique to assess peripheral endothelial function by measuring modifications in digital pulse volume during reactive hyperemia,and represents a non-invasive,reproducible and operator-independent tool able to detect precocious *** narrative review aimed to provide an overview of the most important papers regarding ED detection by EndoPat 2000 in children and adolescents with different endocrine diseases.A comprehensive search of English language articles was performed in the MEDLINE database without using other search filters except the publication interval between 2005 and 2020.

关键词： Pediatric diabetes mellitus Pediatric endocrinopathies Metabolic syndrome cancer survivors Endothelial dysfunction Peripheral artery tonometry

Research status of internet-delivered cognitive behavioral therapy in cancer patients

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World Journal of Psychiatry 2023年第11期13卷 831-837页

作者： Bing-Rui Li Jing Wang Operating Room The Fourth Affiliated Hospital of China Medical UniversityShenyang 110033Liaoning ProvinceChina

The latest global cancer burden data released by the International Agency for Research on cancer of the World Health Organization in 2020 shows that there were 19.29 million new cancer cases worldwide,with 4.57 million in China,ranking *** number of cancer survivors is increasing,with a 5-year survival rate exceeding 85%,but there are emotional *** behavioral therapy(CBT)can improve negative emotions and has significant effects on ***,there is a limited number of physicians and high costs,so internet interventions have become a *** feasibility of web-based interventions for breast cancer patients has been *** on internet-delivered CBT is also *** purpose of this study was to review the concept of web-based CBT and its application status in cancer survivors,in order to provide relevant intervention for scholars and provide reference and supplement for patients to provide psychological therapy.

关键词： cancer survivors Network Cognitive behavioral therapy Negative emotions

cancer Cure Decision Support System Based on Lda Topic Modelling

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Cancer Cure Decision Support System Based on Lda Topic Model...

作者： Samuel Kipchumba Lebo 北京理工大学

学位级别：硕士

Due to advancement in the use of the internet by cancer patients worldwide to share their medical experiences and survivorship stories,there is a need to extract knowledge from the stories using text mining *** self-authored blogs provide a firsthand experience that can inspire and motivate new victims in seeking *** story is profiled with treatments and cancer *** work presents a Gazetteer NER and topic modeling using LDA with controlled *** Gazetteer uses UMLS Meta-thesaurus,local dictionary,POS and local filters to recognize entities from *** Key phrase Extraction Algorithm(KEA),these entities are used for annotating documents in the corpus and training KEA model which is used for generating keywords for all *** are modeled using LDA with Bag of Keywords(BOK),Topics generated by vocabulary controlled LDA shows clear topic *** a story being read by the patient as the actual query,similarity algorithm is used to calculate similarity of stories and their similarity index ranked to establish most similar stories,NER is tested on biotext corpus and it performs with a precision of 88.2%,Recall of 92.1%,F-Measure of 90.1%.The system performance based on similar stories extraction was evaluated on a survey carried out by real users of the system.94% were voted similar,3.2% not similar and 2.8% not sure

关键词： cancer survivors Stories LDA KEA NER