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Effectiveness and safety of generic and brand direct acting antivirals for treatment of chronic hepatitis C

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World Journal of Clinical Cases 2022年第34期10卷 12566-12577页

作者： Maheeba Abdulla Aysha Mohamed Al Ghareeb Hamed Ali Hasan Yusuf Husain Nafeesa Mohammed Jehad Al Qamish Department of Internal Medicine Salmaniya Medical ComplexArabian Gulf UniversityManama 2904Bahrain Department of Internal Medicine Salmaniya Medical ComplexManama 2904Bahrain Internal Medicine Department Ibn AlNafees HospitalManama 3302Bahrain

BACKGROUND Direct acting antivirals(DAAs)are a very effective treatment for hepatitis C virus(HCV).However,brand DAAs are *** licensing of cheaper generic DAAs may address this issue,but there is a lack of clinical studies comparing the efficacy of generic vs brand DAA *** To compare the efficacy and safety of generic against brand DAAs for chronic hepatitis C treatment in *** This was a retrospective observational study involving 289 patients with chronic HCV infection during 2016 to *** were 149 patients who were treated with brand DAAs,while 140 patients were treated with generic *** used DAAs were Ombitasvir/Paritaprevir/Ritonavir±Dasabuvir±Ribavirin,and Sofosbuvir/Daclatasvir±*** at 12 wk post treatment was the main outcome *** Overall,87 patients(30.1%)had cirrhosis and 68.2%had genotype 1 HCV *** 12 wk post treatment,SVR was achieved by 271(93.8%)of the *** patients who were treated with generic medications,134(95.7%)achieved SVR at 12 wk post treatment,compared to 137(91.9%)among those treated with brand medications(P=0.19).Having cirrhosis[odds ratio(OR):9.41,95%confidence interval(CI):2.47–35.84]and having HCV genotype 3(OR:3.56,95%CI:1.03–12.38)were significant independent predictors of not achieving *** transaminase,gamma-glutamyl transpeptidase,and total bilirubin levels decreased significantly following therapy with both generic and brand *** Generic and brand DAAs demonstrate comparable effectiveness in the treatment of chronic hepatitis C *** are safe and equally effective in improving biochemical markers of hepatic inflammation.

关键词： Hepatitis C virus Direct acting antivirals Generic brand Sofosbuvir Ombitasvir Ledipasvir Daclatasvir Paritaprevir Ritonavir Dasabuvir Ribavirin Sustained virologic response

Theoretical analysis of brand-building of e-commerce platforms

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China Finance and Economic Review 2016年第4期5卷 120-129页

作者： Guan Guanjun the College of Business Administration in Capital University of Economics and Business of China

brand-building is inevitable for e-commerce platforms,based on the economic theory of heterogeneous perfect *** investing heterogeneous factors,such as innovative entities into the platforms,their basic business can achieve a natural monopoly in the market,which constitutes a necessary condition for them to build their brands.E-commerce platforms have invalidated the traditional hypothesis of asset specificity,and its value-added business targets brand-building by selling products of multiple varieties and in small batches.

关键词： e-commerce platform brand monopolistic competition heterogeneous perfect competition

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brand & Market

China Textile 2007年第10期 42-43页

作者： Wang Ting

The enterprises in Jiangsu Province,due to the special geographic location,mainly focus on trade and OEM for foreign garment company in early times. As the view of

关键词： brand Market

brand Narration and Fashion Films

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Journalism and Mass Communication 2017年第6期7卷 292-304页

作者： Simonetta Buffo Università Cattolica del Sacro Cuore and Istituto Marangoni Milan Italy

Starting from the new approaches of brand communication in New Millennium Era, we show why, according to us,the fashion film is a powerful tool in defining and strengthening the visual identity of a fashion brand. Our analysisis focused on ordering the different kinds of narration in this special category of orl-line videos and we discover thatthey work about the three fundamental parameters of the Visual Identity Model.

关键词： fashion film brand narration branded contents video on line native advertising

brand Construction of Agricultural Enterprises:A Case Study of Hubei Hanway Ecological Agriculture Group

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Asian Agricultural Research 2016年第12期8卷 24-28,34页

作者： Yi YU Xingxing MEI Henan University of Animal Husbandry and Economy

brand construction of agricultural enterprises is a fundamental path for industrialized development of agriculture,an essential measure for increasing agricultural efficiency and farmers' income,and also an effective approach for development of agricultural modernization. Effective carrier of brand construction is agricultural enterprise. However,at present,there are problems of weak awareness of most agricultural enterprises,low science and technology content of products of agricultural enterprises,lack of carrier for brand construction,and imperfect mechanism of survival of the fittest brand. On the basis of successful experience of Hubei Hanway Ecological Agriculture Group,this paper came up with theoretical conception for brand construction of agricultural enterprises in China from raising social recognition of brands,increasing science and technology content of brand products,improving management and control of quality and safety of brand products,and cultivating effective carrier for brand construction.

关键词： Agricultural enterprises brand Hanway Agricultural modernization

brand Strategy and Japan's Soft Power

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Asian Agricultural Research 2015年第3期7卷 4-7页

作者： Xing YAN School of Political Science and Public Administration China University of Political Science and Law

The 21st century is the time of brand strategy showing its position and importance in operation of *** rise of the brand strategy in operation and management of enterprises has profound social and operation *** development process of brand strategy also reflects evolution of market economy.A country's cultural influence power depends on its brand *** essential task of brand promotion for a county is to narrow the gap between original image and target image,change the past or one-sided image of the public to products of the country,and implement effective communication and propaganda with the aid of related resource system in the country's soft power,and accept new excellent ***,lifting national soft power is to set up distinct and charming national brand or national *** influence power with culture and communication as core is the direct manifestation of a country's core *** is an outstanding feature of a country's *** stretching can promote liftoff of national *** expanding international market,famous brands will play a more and more important role.

关键词： brand brand strategy Soft power Japan

brand Development Strategy Study of Shanghai Roewe

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Brand Development Strategy Study of Shanghai Roewe

brand Marketing in an era of big data

2014中国汽车工程学会年会

作者： Liu Jing Chen Lihua Zhang Xujiao Shanghai University of Engineering Science Department of Management

In the basis of discussing Roewe’s brard development and strategy,this article analyze Roewe’s brand development strategy detailed by the tools of SWOT analysis and put forward further improvement strategy.

关键词： brand strategy roewe

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International Journal of Technology Management 2014年第10期 6-8页

作者： Shaozong Chai Beijing Inistitute of Economics and Management

In the digital age, people＇ s lifestyles and ways of thinking are in a series of changes, this change also makes it a big shift in consumer attitudes. It gives consumers a broader perspective, while also improving the self-consciousness of consumers. These effects will no longer fully believe in traditional consumer marketing ＂bombing＂ the dissemination and indoctrination, they are more inclined to be questioned brands and products, and they can express their views on the basis that affects other people. In this era of environment, if businesses and vendors for their view is indifferent attitude, they will lose a lot of attention to the crowd, and also it makes the influence of the traditional marketing model spread greatly reduced.

关键词： big data brand Marketing

Analysis on the Regional brand Operation Mode for Carya Cathayensis——A Case Study of Lin'an in Zhejiang

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Asian Agricultural Research 2013年第11期5卷 28-32,37页

作者： Xiaoling TU Yueli ZHANG School of Economics & Management Zhejiang A&F University

Lin'an City has a long history of growing,processing and selling Carya Cathayensis,a traditional special local product for which the city is well *** recent years,Lin'an Carya Cathayensis gives full play to the industry cluster advantages and gains the reputation of"regional name brand of Zhejiang".However,it faces the predicament of regional brand operation,so industry transformation and upgrading as well as intensive farming for this brand are inevitable and *** paper analyzes the current regional brand operation mode of Carya Cathayensis in Lin'an to find out that the growth of this brand is constrained by messy business entities,weak brand protection effect,significant lemon market effect,insufficient industry association efforts and wanting brand culture construction,thus it puts forward the conception of a business alliance based regional brand operation mode for the Carya Cathayensis in Lin'*** results of this study shall provide theoretical guidance and empirical basis for the marketing practice of the regional brand of Carya Cathayensis in Lin'an.

关键词： Carya Cathayensis of Lin’an Regional brand Operati