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body composition changes following chemotherapy for testicular germ cell tumor:obesity is the long-term problem

Asian Journal of Andrology 2022年第5期24卷 458-462页

作者： Yuki Takai Sei Naito Hidenori Kanno Atsushi Yamagishi Mayu Yagi Toshihiko Sakurai Hayato Nishida Takuya Yamanobe Tomoyuki Kato Norihiko Tsuchiya Department of Urology Yamagata University Faculty of MedicineYamagata 990-9585Japan

Metabolic syndrome is a long-term complication of systemic chemotherapy for testicular germ cell tumor(TGCT).It is believed to be caused by secondary hypogonadism or toxic medicines because of orchidectomy followed by systemic *** this study,changes in the body composition of patients over time were quantitatively analyzed up to 24 months after *** study retrospectively analyzed 44 patients with TGCT who underwent chemotherapy at our institution from January 2008 to December *** and visceral fat areas and psoas and skeletal muscle areas were measured by computed tomography before and immediately after chemotherapy as well as 3 months,6 months,12 months,and 24 months after *** subcutaneous and visceral fat indices and psoas and skeletal muscle indices were calculated as each area divided by body height *** total fat area had already significantly increased 3 months after the initiation of chemotherapy(P=0.004).However,it did not return to prechemotherapeutic levels even at 24 months after *** skeletal muscle area was significantly decreased at the end of chemotherapy(P<0.001);however,the value returned to baseline within 12 *** multivariable analysis,the prechemotherapeutic skeletal muscle index and number of chemotherapy cycles were independently associated with the reduction of skeletal muscle at the end of chemotherapy(P=0.001 and P=0.027,respectively).In patients with TGCT,skeletal muscle mass decreased during chemotherapy and recovered within 12 months,whereas fat mass progressively increased from the initiation of chemotherapy until 24 months after chemotherapy.

关键词： body composition chemotherapy obesity sarcopenia secondary hypogonadism testicular cancer

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body composition and metabolic syndrome in patients with type 1 diabetes

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World Journal of Diabetes 2024年第1期15卷 81-91页

作者： Qiong Zeng Xiao-Jing Chen Yi-Ting He Ze-Ming Ma Yi-Xi Wu Kun Lin Department of Neurology The First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Medical College Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of Endocrinology The First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

BACKGROUND In recent years,the prevalence of obesity and metabolic syndrome in type 1 diabetes(T1DM)patients has gradually *** resistance in T1DM deserves *** is necessary to clarify the relationship between body composition,metabolic syndrome and insulin resistance in T1DM to guide clinical treatment and *** To assess body composition(BC)in T1DM patients and evaluate the relationship between BC,metabolic syndrome(MS),and insulin resistance in these *** A total of 101 subjects with T1DM,aged 10 years or older,and with a disease duration of over 1 year were *** impedance analysis using the Tsinghua-Tongfang BC Analyzer BCA-1B was employed to measure various BC *** and laboratory data were collected,and insulin resistance was calculated using the estimated glucose disposal rate(eGDR).RESULTS MS was diagnosed in 16/101 patients(15.84%),overweight in 16/101 patients(15.84%),obesity in 4/101(3.96%),hypertension in 34/101(33.66%%)and dyslip-idemia in 16/101 patients(15.84%).Visceral fat index(VFI)and trunk fat mass were significantly and negatively correlated with eGDR(both Pbody fat percentage and visceral fat ratio compared to male *** logistic regression analysis revealed that significant factors for MS included eGDR[P=0.017,odds ratio(OR)=0.109],VFI(P=0.030,OR=3.529),and a family history of diabetes(P=0.004,OR=0.228).Significant factors for hypertension included eGDR(Pbody mass index and waist-to-hip ratio in Chinese individuals with *** analysis,specifically identifying visceral fat(trunk fat),may play an important role in identifying the increased risk of

关键词： body composition Metabolic syndrome Insulin resistance Visceral fat Estimated glucose disposal rate

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Effects of the Dietary Probiotic Clostridium butyricum on Intestine Digestive and Metabolic Capacities, SCFA Content and body composition in Marsupenaeus japonicus

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Journal of Ocean University of China 2018年第3期17卷 690-696页

作者： DUAN Yafei DONG Hongbiao WANG Yun ZHANG Yue ZHANG Jiasong South China Sea Fisheries Research Institute Chinese Academy of Fishery Sciences Guangzhou 510300 China Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization Ministry of Agriculture Guangzhou 510300 China Key Laboratory of Fishery Ecology and Environment Guangdong Province Guangzhou 510300 China

A 56-day feeding trial was performed to evaluate the effects of dietary probiotic Clostridium butyricum(CB) on intestine digestive and metabolic capacities, intestine short-chain fatty acids(SCFA) content and body composition of kuruma shrimp Marsupenaeus japonicus. Shrimp s were randomly allocated into 9 tanks, 30 each, and f ed with diets containing different levels of C. butyricum(1×10~9 cfug^(-1)): 0 mgg^(-1) feed(Control), 100 mgg^(-1) feed(CB-100), 200 mgg^(-1) feed(CB-200), while each level was triplicated. The results indicated that compared with the control group, the intestine pepsin(Pep) activity and 5-hydroxytryptamine(5-HT) concentration of two C. butyricum group s were both increased. Amylase(AM Y) and lipase(LPS) activities wer e only induced in CB-200 group. Alanine aminotransferase(ALT) and aspartate aminotransferase(A ST) activities of two C. butyricum group s showed no significant change. The α-amylase(AM Y) gene expression was induced in CB-200 group, and tryp sin gene expression of two C. butyricum treated group s were both induced. Intestine SCFA content and body composition analysis showed that the contents of propionic acid, butyric acid and the crude protein of two C. butyricum group s were all higher than those of control. These results revealed that C. butyricum can modulate intestine digestive and metabolic capacities, improve intestine SCFA content and body crude protein content in M. japonicus.

关键词： Marsupenaeus japonicus Clostridium butyricum intestine digestive capacity short-chain fatty acid body composition

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Leisure-time physical activity,anthropometrics,and body composition as predictors of quality of life domains after spinal cord injury:an exploratory cross-sectional study

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Neural Regeneration Research 2022年第6期17卷 1369-1375页

作者： Melody N.Mickens Paul Perrin Jacob A.Goldsmith Refka E.Khalil William E.Carter III Ashraf S.Gorgey Division of Physical Medicine and Rehabilitation University of Utah School of MedicineSalt Lake CityUTUSA Department of Psychology Virginia Commonwealth UniversityRichmondVAUSA Spinal Cord Injury&Disorders Hunter Holmes McGuire VA Medical CenterRichmondVAUSA Department of Physical Medicine and Rehabilitation Virginia Commonwealth University School of MedicineRichmondVAUSA

The objective of the current work was to examine the relationships between quality of life(QOL)domains in persons with spinal cord injury(SCI)and their levels of weekly leisure-time physical activity(LTPA),anthropometric variables,and body composition *** exploratory cross-sectional study consisted of baseline data collected as part of a randomized clinical trial at a VA Medical Center and SCI center.A convenience sample of 36 community-dwelling persons with SCI participated in the current *** measures included the World Health Organization Quality of Life Short Form(WHOQOL-BREF),Leisure-Time Physical Activity Questionnaire for People with Spinal Cord Injury(LTPAQ-SCI),anthropomorphic measures(waist,hip,and abdominal circumference),and dual-energy x-ray absorptiometry(DXA)to quantify regional and total body *** regression models suggested that engagement in LTPA accounted for 35.7%of the variance in physical health QOL,33.5%in psychological QOL,14.2%in social relationships QOL,and 38.2%in environmental *** measures accounted for 11.3%,3.1%,12.0%,and 6.7%of the variance in these QOL indices,respectively,and DXA indices accounted for 18.7%,17.5%,27.4%,and 21.9%.Within these models,the number of minutes of heavy LTPA per day uniquely predicted physical health QOL,the number of mild LTPA days per week uniquely predicted psychological QOL,and the amount of mild LTPA per day uniquely predicted environmental *** analyses also suggested that android and trunk fat,as well as supine waist and abdominal circumferences,were positively associated with social relationships *** individuals with SCI to engage in LTPA may robustly enhance multiple aspects of QOL while reducing the risk for cardiovascular and metabolic morbidities associated with ***,this may lead to a further understanding of how QOL may impact longitudinal intervention *** study protocol and procedures were reviewed and appro

关键词： anthropometrics body composition dual-energy-x-ray absorptiometry exercise physical activity quality of life spinal cord injury

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Effects of different levels of sweet potato in feeds on body composition and digestive enzymes activities of A postichopus japonicas Selenka

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Journal of Oceanology and Limnology 2018年第5期36卷 1835-1842页

作者： ZHAO Bin HU Wei LI Chenglin HAN Sha XU Tao Marine Biology Institute of Shandong Province Qingdao 266104China Shandong Province Fisheries Technology Extension Station Jinan 250013China Homey Foods Co.Ltd. Weihai 264305China

The aim of this study was to test the ef fects of including sweet potato tuber and stem powder in feed on the body composition and digestive enzyme activities of the sea cucumber A postichopus japonicas Selenka. Dif ferent proportions of sweet potato tuber and stem powders(from 10% to 50%) were added into compound feeds, which were supplied to A. japonicas during a 60-day experiment. The results showed that the two sweet potato ingredients had different eff ects on the nutrient contents of the sea cucumber body wall. The group supplied with feed containing 20% sweet potato tuber powder(T2) had the highest level of crude protein in body walls(P body walls among the groups(P >0.05). In all the groups fed with powdered sweet potato tubers(T groups), the proportions of glutamic acid and lysine in body walls were higher than those in the control, whereas the proportion of methionine decreased slightly. Diff erent proportions of sweet potato ingredients in compound feeds also af fected digestive enzyme activities in the sea cucumbers. The activities of protease and lipase first increased and then gradually decreased with increasing proportions of sweet potato materials in the feed. The highest protease activity was in the T2 and the group and the highest lipase activity was in the 10% sweet potato stem(S1) group. These results show that feed components can stimulate digestive enzyme activities in sea cucumber, and that the proportions of tubers and stems of sweet potato in feed can be adjusted to improve the digestion and growth of A. japonicas in marine farms.

关键词： Apostichopus japonicas Selenka sweet potato body composition digestive enzymes

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Influence of stocking density on growth, body composition and energy budget of Atlantic salmon Salmo salar L. in recirculating aquaculture systems

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Chinese Journal of Oceanology and Limnology 2014年第5期32卷 982-990页

作者：刘宝良刘鹰刘子毅仇登高孙国祥李贤 Institute of Oceanology Chinese Academy of Sciences

Atlantic salmon Salmo salar were reared at four stocking densities--high density D1 （final density -39 kg/m^3）, medium densities DE （-29 kg/m^3） and D3 （~19 kg/m^3）, and low density D4 （-12 kg/m^3）- for 40 days to investigate the effect of stocking density on their growth performance, body composition and energy budgets. Stocking density did not significantly affect specific growth rate in terms of weight （SGRw） but did affect specific growth rate in terms of energy （SGRe）. Stocking density significantly influenced the ration level （RLw and RLe）, feed conversion ratio （FCRw and FCRe） and apparent digestibility rate （ADR）. Ration level and FCRw tended to increase with increasing density. Fish at the highest density D~ and lowest density D4 showed lower FCRe and higher ADR than at medium densities. Stocking density significantly affected protein and energy contents of the body but did not affect its moisture, lipid, or ash contents. The expenditure of energy for metabolism in the low-density and high-density groups was lower than that in the medium-density groups. Stocking density affected energy utilization from the feces but had no effect on excretion rate. The greater energy allocation to growth at high density and low density may be attributed to reduced metabolic rate and increased apparent digestibility rate. These findings provide information that will assist selection of suitable stocking densities in the Atlantic-salmon-farming industry.

关键词： stocking density Atlantic salmon growth body composition energy budget recirculatingaquaculture system

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Hydration status,body composition,and anxiety status in aeronautical military personnel from Spain:a crosss-ectional study

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Military Medical Research 2022年第2期9卷 184-192页

作者： Alejandra Carretero-Krug Nataliaúbeda Carlos Velasco Juan Medina-Font Trinidad Trujillo Laguna Gregorio Varela-Moreiras Ana Montero Departamento Ciencias Farmacéuticas y de la Salud Facultad de FarmaciaUniversidad San Pablo-CEUCEU UniversitiesUrbanización Montepríncipe28660 Boadilla del MonteSpain Centro de Instrucción de Medicina Aeroespacial Ejército del Aire28850 Torrejón de ArdozMadridSpain

Background: An adequate hydration status is critical to ensure efficiency during mental and physical *** goal was to assess the hydration status of a Spanish group of aeronautical military men and to determine the association of hydration status with body composition and ***: A total of 188 men were evaluated through a validated hydration questionnaire, anthropometric and biochemical parameters, and an anxiety questionnaire. Based on these methods, the criteria of hydration were ***: Of the total sample, 81% met the hydration criteria(urine color = well hydrated, water balance ≥0 ml, and total water intake/weight ≥35 ml/kg), and 19% did not meet the hydration criteria(urine color = not sufficiently hydrated or dehydrated, water balance body mass index [(26.3±3.1) kg/m;vs.(25.2±2.8) kg/m;], body fat [(22.3±5.6)% vs.(18.3±6.5)%], urine specific gravity, and urine color. Using a logistic binary regression model, hydration status was related significantly with the percentage of body fat(P=0.004), but no relation was found with age, comorbidities, or medications. Furthermore, total water intake/weight was positively correlated with percentage of body water(r=0.357, P=0.000) and negatively with body fat(kg)(r=–0.427, P=0.000), percentage of body fat(r=–0.405, P=0.000), and waist/hip ratio(r=–0.223, P=0.002). Based on a linear regression model, total water intake/weight was related significantly with percentage of body fat(P=0.001) and percentage of body water content(P=0.035). No relation was found, however, with waist/hip ratio, age, comorbidities, or ***: These findings all suggest a relationship between hydration status and body composition but

关键词： Hydration status Military aeronautical personnel body composition Anxiety status Water intake

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Effect of dietary genistein on growth performance,digestive enzyme activity,and body composition of Nile tilapia Oreochromis niloticus

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Chinese Journal of Oceanology and Limnology 2015年第1期33卷 77-83页

作者：陈栋王蔚汝少国 College of Marine Life Sciences Ocean University of China School of Environmental and Municipal Engineering Qingdao Technological University

An 8-week feeding experiment was performed to evaluate the effect of dietary genistein on growth performance,body composition,and digestive enzymes activity of juvenile Nile tilapia(Oreochromis niloticus).Four isonitrogenous and isoenergetic diets were formulated containing four graded supplements of genistein:0,30,300,and 3 000 μg/*** diet was randomly assigned in triplicate to tanks stocked with 15 juvenile tilapia(10.47±1.24 g).The results show that 30 and 300 μg/gdietary genistein had no significant effect on growth performance of Nile tilapia,but the higher level of genistein(3 000 μg/g)significantly depressed the final body weight and specific growth *** was no significant difference in survival rate,feed intake,feed efficiency ratio or whole body composition among all dietary *** assay of digestive enzymes showed that the diet containing 3 000 μg/ggenistein decreased stomach and hepatopancreas protease activity,and amylase activity in the liver and intestine,while a dietary level of300 μg/g genistein depressed stomach protease and intestine amylase ***,no significant difference in stomach amylase activity was found among dietary ***,the results of the present study indicate that a high level of dietary genistein(3 000 μg/g,or above) would significantly reduce the growth of Nile tilapia,partly because of its inhibitory effect on the activity of major digestive ***,the detrimental effects of genistein,as found in soybean products,should not be ignored when applied as an alternative ingredient source in aquaculture.

关键词： genistein growth digestive enzyme activities body composition Nile tilapia

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Relationships of body composition and adipocytokines with outcomes in metastatic castration-resistant prostate cancer patients receiving docetaxel chemotherapy

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Asian Journal of Andrology 2023年第4期25卷 520-527页

作者： Jun-Hong Li Xing-Ming Zhang Xiao-Jie Bian Wei-Jie Gu Fang-Ning Wan Bo Dai Ding-Wei Ye Department of Urology Fudan University Shanghai Cancer CenterShanghai 200032China Shanghai Genitourinary Cancer Institute Shanghai 200032China

We evaluated the relationships of body composition and serum adipocytokine levels with progression-free survival(PFS)and overall survival(OS)in metastatic castration-resistant prostate cancer(mCRPC)patients receiving *** medical records of mCRPC patients who received docetaxel between January 2011 and December 2015 at Fudan University Shanghai Cancer Center(Shanghai,China)were *** following body composition parameters were calculated using computed tomography:skeletal muscle index(SMI),visceral adipose tissue index(VATI),and subcutaneous adipose tissue index(SATI).Pretreatment serum adipocytokine levels,including interleukin 6,insulin,leptin,monocyte chemoattractant protein-1,adiponectin,and resistin,were measured using the multiplex bead-based *** regression and Kaplan–Meier methods were used for survival *** the 453 mCRPC patients initially identified,105 were included in the *** VATI group patients had longer PFS(median,10 months vs 7 months,P=0.008)and OS(median,24 months vs 15 months,P=0.017),compared with low VATI group *** and SATI were not significantly associated with PFS or *** the six detected adipocytokines,only leptin was associated with mCRPC *** leptin group patients had shorter PFS(median,7 months vs 12 months,P=0.0018)and OS(median,17 months vs 22 months,P=0.042),compared with low leptin group *** analysis showed that a high VATI was an independent protective factor for PFS and OS,while a high leptin level was an independent risk factor for PFS and ***,VATI and serum leptin levels could provide important information concerning mCRPC prognosis.

关键词： adipocytokines body composition castration-resistant prostate cancer chemotherapy prognosis

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Statistical Medical Pattern Recognition for body composition Data Using Bioelectrical Impedance Analyzer

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Computers, Materials & Continua 2021年第5期67卷 2601-2617页

作者： Florin Valentin Leuciuc Maria Daniela Craciun Iulian Stefan Holubiac Mazin Abed Mohammed Karrar Hameed Abdulkareem Gheorghe Pricop Stefan cel Mare University of Suceava Suceava720229Romania The Interdisciplinary Research Center for Human Motricity and Health Sciences Suceava720229Romania College of Computer Science and Information Technology University of AnbarRamadi31001Iraq College of Agriculture Al-Muthanna UniversitySamawah66001Iraq

Identifying patterns,recognition systems,prediction methods,and detection methods is a major challenge in solving different medical *** categories of devices for personal and professional assessment of body composition are *** impedance analyzer is a simple,safe,affordable,mobile,non-invasive,and less expensive alternative device for body composition *** the body composition pattern of different groups with varying age and gender is a major challenge in defining an optimal level because of the body shape,body mass,energy requirements,physical fitness,health status,and metabolic ***,this research aims to identify the statistical medical pattern recognition of body composition data by using a bioelectrical impedance *** previous studies,a pattern was identified for four indicators that concern body composition(e.g.,body mass index(BMI),body fat,muscle mass,and total body water).The novelty of our study is the fact that we identified a recognition pattern by using medical statistical methods for a body composition that contains seven indicators(e.g.,body fat,visceral fat,BMI,muscle mass,skeletal muscle mass,sarcopenic index,and total body water).The youth that exhibited the body composition pattern identified in our study could be considered *** deviation of one or more parameters outside the margins of the pattern for body composition could be associated with health issues,and more medical investigations would be needed for a *** is considered a valid and reliable device to assess body composition along with medical statistical methods to identify a pattern for body composition according to the age,gender,and other relevant parameters.

关键词： Statistical method pattern recognition body composition assessment

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