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blood neutrophil extracellular traps:a novel target for the assessment of mammary health in transition dairy cows

Journal of Animal Science and Biotechnology 2023年第3期14卷 1068-1079页

作者： Luyi Jiang Huizeng Sun Fengfei Gu Jin He Fengqi Zhao Jianxin Liu Institute of Dairy Science College of Animal SciencesZhejiang UniversityHangzhouChina Ministry of Education Key Laboratory of Molecular Animal Nutrition Zhejiang UniversityHangzhouChina Institute of Animal Genetics and Reproduction College of Animal SciencesZhejiang UniversityHangzhouChina Department of Animal&Veterinary Sciences University of VermontBurlingtonUSA

Background:Mammary health is important for transition dairy cows and has been well recognized to exert decisive effects on animal ***,the factors influencing mammary health are still *** somatic cell count(DSCC)could reflect the mastitis risk since it is the percentage of neutrophils plus lymphocytes in total somatic cells and could be reflective of mammary health of dairy *** work aimed to investigate the assessment and prognosis of the health of transition cows based on blood neutrophil extracellular traps(NETs).Results:Eighty-four transition Holstein dairy cows were *** serum was sampled in all the animals at week 1 pre-and postpartum,and milk was sampled at week 1 *** on the DSCC in milk at week 1,cows with lower(7.4%±4.07%,n=15)and higher(83.3%±1.21%,n=15)DSCCs were *** DSCC cows had higher levels of red blood cell counts(Pmilk NETs(Pblood-milk barrier indicators,including serumβ-casein(P=0.05)and milk immunoglobulin G2(P=0.09),than those of low DSCC *** addition,lower concentrations of serum nutrient metabolites(cholesterol and albumin)(Pblood in transition dairy cows may damage the integrity of the blood-milk barrier and thereby increase the risk for

关键词： blood-milk barrier Differential somatic cell count Mastitis risk Neutrophil extracellular traps

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