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Robust scalable reversible strong adhesion by gecko-inspired composite design

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Friction 2022年第8期10卷 1192-1207页

作者： Xiaosong LI Pengpeng BAI Xinxin LI Lvzhou LI Yuanzhe LI Hongyu LU Liran MA Yonggang MENG Yu TIAN State Key Laboratory of Tribology Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China

Bio-inspired reversible adhesion has significant potential in many fields requiring flexible grasping and manipulation,such as precision manufacturing,flexible electronics,and intelligent *** extensive efforts for adhesive synthesis with a high adhesion strength at the interface,an effective strategy to actively tune the adhesion capacity between a strong attachment and an easy detachment spanning a wide range of scales has been ***,we report a novel soft-hard-soft sandwiched composite design to achieve a stable,repeatable,and reversible strong adhesion with an easily scalable performance for a large area ranging from~1.5 to 150 cm2 and a high load ranging from~20 to 700 *** studies indicate that this design can enhance the uniform loading for attachment by restraining the lateral shrinkage in the natural state,while facilitate a flexible peeling for detachment by causing stress concentration in the bending state,yielding an adhesion switching ratio of~54 and a switching time of less than~0.2 *** design is further integrated into versatile grippers,climbing robots,and human climbing grippers,demonstrating its robust scalability for a reversible strong *** biomimetic design bridges microscopic interfacial interactions with macroscopic controllable applications,providing a universal and feasible paradigm for adhesion design and control.

关键词： biomimetic design reversible adhesion composite cross-scale robotics

Computational design and Fabrication of a Bending-Active Structure Using Fiberglass:A Bioinspired Pavilion Mimicking Marine Microorganism Radiolaria

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Journal of Bionic Engineering 2022年第2期19卷 471-482页

作者： Bosheng Liu Tanvir R.Faisal School of Architecture and design University of Louisiana at LafayetteLafayetteLA 70503USA Department of Mechanical Engineering University of Louisiana at LafayetteLafayetteLA 70503USA

Bio-inspired architectural designs are often superior for their aesthetics and structural *** forms and loading states of a biological structure is complex as it requires a delicate balance among geometry,material properties,and interacting *** goal of this work is to design a biomimetic,ultra-lightweight,bending-active structure utilizing an informed integral design approach,and thereby constructing a self-supporting cellular pavilion.A bioinspired pavilion has been designed and constructed based on the natural cellular organization observed in Radiolaria,a deep-sea *** cellularity was mimicked via Voronoi tessellation in the structure of the pavilion,whose structural performance was evaluated using finite element ***,funicular structure design strategies were studied with a focus on cellular distributions and concentration responding to areas with high structural *** computer aided custom designed pavilion was constructed with engineered,in-house fabricated fiberglass composite *** bending-active lightweight structure was also validated through material performance inquiry,a partial full-scale cellular assembly,and the full-size pavilion *** work contributes to the design approach comprising a bending-active form-finding schematic strategy to construct the elastic bending-active structure physically and simulate computationally within the context of nature inspired innovative lightweight structure design.

关键词： biomimetic design Double-curved shell pavilion Voronoi tessellation Bending-active structures Finite element analysis

Synovial fluid-inspired biomimetic lubricating microspheres:Zwitterionic polyelectrolyte brushes-grafted microgels

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Friction 2023年第6期11卷 938-948页

作者： Guoqiang LIU Yang FENG Xiaohua GAO Zhuo CHEN Nan ZHAO Feng ZHOU Weimin LIU Center of Advanced Lubrication and Seal Materials State Key Laboratory of Solidification ProcessingNorthwestern Polytechnical UniversityXi’an710072China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China

Synovial fluid is made up of various biomacromolecules,including hyaluronic acid,aggrecans,lubricins,and phosphatidylcholine lipid,which are assembled onto the surface of articular cartilage in a gel *** them,brush-like biomacromolecules or assemblies have a vital effect on human joint *** by this,the combination of brush-like molecular structures and gel-like assembly may be an efficient approach for the synthesis of biomimetic lubricating *** from the lubrication system of human joints,poly(2-methacryloyloxyethyl phosphorylcholine)(PMPC)brushes grafted poly(N-isopropylacrylamide-co-acrylic acid)(poly(NIPAAm-co-AA))microgels,abbreviated as MBs-g-MGs,were synthesized as one kind of biomimetic lubricating *** is worth noting that this bionic strategy considered both molecular structure and assembled form,which enabled this hairy microgel to achieve low friction in aqueous ***,the effective lubrication was still achieved when using MBs-g-MGs at high temperature,indicating that this microgel maintains a good lubricating effect over a wide range of *** addition,this kind of microgel possessed good biocompatibility,which laid the foundation for potential biomedical *** beyond,these biomimetic microgels may provide an effective lubricating effect for water-based sliding interfaces,especially in biomedical systems.

关键词： biomimetic design zwitterionic polyelectrolyte brushes polymeric microgels aqueous lubrication

Bionic Volute Tongue Optimization design of Multi-blade Centrifugal Fan Inspired by the Wave Leading-edge of Humpback Whale Flippers

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Journal of Bionic Engineering 2023年第5期20卷 2209-2227页

作者： Yang Liu Qi Yuan Ziqian Xu Liming Wu Xiaomin Liu School of Energy and Power Engineering Xi’an Jiaotong UniversityXi’an710049China Guangdong Midea Air-Conditioning Equipment Co. Ltd.Foshan528311China Department of Electromechanical and Vehicle Engineering Taiyuan UniversityTaiyuan030032China

The volute tongue can split the gas in the multi-blade centrifugal fan to make the gas flow to the volute outlet as much as ***,the unsteady axial deflection of the gas in the impeller results in different air flow angles at the outlet of the impeller at different blade *** seriously affects the flow near the volute *** wave leading-edge structure of humpback whale flippers has a very high flow control effect under complex flow ***,the wave leading-edge structure is studied in this paper and applied to the optimization design of multi-blade centrifugal fan volute ***,based on the wave leading-edge structure of humpback whale flippers,three-dimensional wave leading-edge airfoils with different wave direction angles are established to judge the adaptability of the new wave leading-edge structure under different attack ***,aiming at the internal flow field and noise characteristics of multi-blade centrifugal fan,a bionic volute tongue optimization design method is proposed,and studied its influence on the internal flow field and noise characteristics of the *** results show that when the wave direction angle is 45°,the wave leading-edge structure can effectively suppress the generation of the leading-edge separation vortex and the shedding of the wake vortex,which is also helpful to reduce the *** bionic volute tongue with the wave leading-edge structure can adapt to the situation that the impeller outlet air flow angle is *** the maximum volume flow rate operating point,the static pressure recovery coefficient of the bionic volute tongue fan is increased by about 5%compared to the original fan,the air volume is increased by 5.16%,and the noise is reduced by 0.6 dB.

关键词： Multi-blade centrifugal fan Airfoil Volute tongue biomimetic design Aerodynamic noise

A highly-selective biomimetic potassium channel

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National Science Review 2024年第8期11卷 187-195页

作者： Junliang Zhu Hu Qiu Wanlin Guo Key Laboratory for Intelligent Nano Materials and Devices of the Ministry of Education State Key Laboratory of Mechanics and Control for Aerospace Structures Institute for Frontier ScienceNanjing University of Aeronautics and Astronautics

Reproducing the outstanding selectivity achieved by biological ion channels in artificial channel systems can revolutionize applications ranging from membrane filtration to single-molecule sensing technologies,but achieving this goal remains a ***,inspired by the selectivity filter structure of the KcsA potassium channel,we propose a design of biomimetic potassium nanochannels by functionalizing the wall of carbon nano tubes with an array of arranged carbonyl oxygen *** extensive molecular dynamics simulations show that the biomimetic nanochannel exhibits a high K+permeation rate along with a high K+/Na+selectivity *** free energy calculations suggest that the low Na+permeability is the result of the higher energy barrier for Na+than K+at the channel entrance and ion binding *** addition,reducing the number of ion binding sites leads to an increase in the permeation rate but a decrease in *** findings not only hold promise for the design of high-performance membranes but also help understand the mechanism of selective ion transport in biological ion channels.

关键词： biomimetic design carbon nanotube K+/Na+ selectivity molecular dynamics simulations

Haversian bone-mimicking bioceramic scaffolds enhancing MSC-macrophage osteo-imunomodulation

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Progress in Natural Science:Materials International 2021年第6期31卷 883-890页

作者： Bingjun Zhang Meng Zhang Yuhua Sun Mengmeng Li Fei Hana Chengtie Wu State Key Laboratory of High-Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences

The interaction between immune cells and bone forming cells plays a vital role in maintaining the homeostasis of the skeletal system, and is regulated by the three-dimensional structure of tissues. Whether the construction of biomaterials can activate or reproduce this spatial “cross-talk” between immune cells and bone forming cells in bone natural formation process is a prerequisite for successful fracture healing and bone regeneration. Herein, a bone marrow mesenchymal stem cells(MSCs)/macrophages-laden Haversian bone-mimicking bioceramic scaffold was successfully prepared through the biomimetic design of biomaterials and 3D printing technology. MSCs and macrophages were respectively distributed in the cancellous bone and Haversian canals of the scaffold to simulate the three-dimensional structure regulation of the cell spatial distribution and multiple intercellular interaction in natural bone tissue, and worked in concert to modulate the scaffold material-mediated osteo-immune microenvironment. The in vitro study revealed that the pro-inflammatory response of macrophages was more significantly inhibited when distributed with MSCs in the scaffolds at a cell ratio of 0.5:1 for co-culture, in comparison with multicellular culture at other ratios and unicellular culture. Meanwhile, MSCs exhibited the relatively high osteogenic potential, most likely via the activation of certain key signaling pathways mediated by macrophagesderived paracrine signaling mediators(OSM, BMP-2, and WNT10b). This work not only establishes a bionic platform for the regulation of multicellular osteo-immune response and regeneration but also offers a promising tissue-engineered biomimetic scaffold with improved immunomodulatory function for promoting bone tissue regeneration.

关键词： Cell spatial distribution MSC-macrophage interaction Immunomodulation Osteogenic differentiation biomimetic design

A hierarchical bilayer architecture for complex tissue regeneration

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Bioactive Materials 2022年第4期7卷 93-106页

作者： Min Yu Dan Luo Jing Qiao Jiusi Guo Danqing He Shanshan Jin Lin Tang Yu Wang Xin Shi Jing Mao Shengjie Cui Yu Fu Zixin Li Dawei Liu Ting Zhang Chi Zhang Zhou Li Yongsheng Zhou Yan Liu Laboratory of biomimetic Nanomaterials Department of OrthodonticsPeking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijing100081China Department of Prosthodontics Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijing100081China CAS Center for Excellence in Nanoscience Beijing Key Laboratory of Micro-nano Energy and SensorBeijing Institute of Nanoenergy and NanosystemsChinese Academy of SciencesBeijing101400China Department of Periodontology The First Clinical DivisionPeking University School and Hospital of StomatologyBeijing100034China State Key Laboratory of Oral Diseases National Clinical Research Center for Oral DiseasesWest China Hospital of StomatologySichuan UniversityChengdu610041China Center of Stomatology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Fourth Division Peking University Hospital of StomatologyBeijing100025China

Engineering a complete,physiologically functional,periodontal complex structure remains a great clinical challenge due to the highly hierarchical architecture of the periodontium and coordinated regulation of multiple growth factors required to induce stem cell multilineage *** biomimetic self-assembly and microstamping techniques,we construct a hierarchical bilayer architecture consisting of intrafibrillarly mineralized collagen resembling bone and cementum,and unmineralized parallel-aligned fibrils mimicking periodontal *** prepared biphasic scaffold possesses unique micro/nano structure,differential mechanical properties,and growth factor-rich microenvironment between the two phases,realizing a perfect simulation of natural periodontal hard/soft tissue *** interconnected porous hard compartment with a Young’s modulus of 1409.00±160.83 MPa could induce cross-arrangement and osteogenic differentiation of stem cells in vitro,whereas the micropatterned soft compartment with a Young’s modulus of 42.62±4.58 MPa containing abundant endogenous growth factors,could guide parallel arrangement and fibrogenic differentiation of stem cells in *** implantation in critical-sized complete periodontal tissue defect,the biomimetic bilayer architecture potently reconstructs native periodontium with the insertion of periodontal ligament fibers into newly formed cementum and alveolar bone by recruiting host mesenchymal stem cells and activating the transforming growth factor beta 1/Smad3 signaling *** together,integration of self-assembly and microstamping strategies could successfully fabricate a hierarchical bilayer architecture,which exhibits great potential for recruiting and regulating host stem cells to promote synergistic regeneration of hard/soft tissues.

关键词： biomimetic design Biphasic scaffold Mineralized collagen Micropatterned arrays Periodontium regeneration

Interactive Kinetic Canopy with Industrial Architecture Legacy Preservation Approach

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Journal of Architectural Research and Development 2020年第2期4卷 1-10页

作者： Hamidreza Sakhaei m.1.in architecture faculty of art and architecturetarbiat modares universityiran

Architecture has long sought to improve both in terms of form,space and other ***,the use of innovative techniques that enhance design is always one of the concerns in the field of *** and Nature-Friendly architecture have always inspired by natural organisms aims to emphasize harmony with the *** another approach,contemporary industrial architecture has a valuable place in this knowledge,and the restoration and preservation of this heritage is a serious *** attractive methods like an integration of new technology and monumental heritage lead to a profound *** this end,designing a canopy using an interactive and kinetic pattern to value this theme can be effective on sustainable development goals in *** canopy which is inspired by biomimetic pattern and natural potentials from the site,responses to external motivation and adapts its kinetic movements to follow human *** innovative techniques are involved with choosing a precise geometrical frame and order,kinetic patterns suitable for the project and finally fabrication of an scale model from actual *** choosing a suitable site that houses building of contemporary industrial architecture such as a railway station,this paper aims at learning from nature to fulfill industrial heritage legacy retention that is in both physical and spiritual interaction with humans.

关键词： Contemporary Industrial Architecture Sustainable Development Smart Canopy Industrial Heritage biomimetic design