Synovial fluid-inspired biomimetic lubricating microspheres:Zwitterionic polyelectrolyte brushes-grafted microgels

作     者：Guoqiang LIU Yang FENG Xiaohua GAO Zhuo CHEN Nan ZHAO Feng ZHOU Weimin LIU Guoqiang LIU;Yang FENG;Xiaohua GAO;Zhuo CHEN;Nan ZHAO;Feng ZHOU;Weimin LIU

作者机构：Center of Advanced Lubrication and Seal MaterialsState Key Laboratory of Solidification ProcessingNorthwestern Polytechnical UniversityXi’an710072China State Key Laboratory of Solid LubricationLanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China 

出 版 物：《Friction》 (摩擦（英文版）)

年 卷 期：2023年第11卷第6期

页      面：938-948页

核心收录：

学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 0836[工学-生物工程] 0702[理学-物理学] 10[医学] 

基　　金：financial support from the National Natural Science Foundation of China(Nos.51905433 and 52175187) the China Postdoctoral Science Foundation(No.2021M692625) the Fundamental Research Funds for the Central Universities(No.3102019JC001) 

主　　题：biomimetic design zwitterionic polyelectrolyte brushes polymeric microgels aqueous lubrication 

摘      要：Synovial fluid is made up of various biomacromolecules,including hyaluronic acid,aggrecans,lubricins,and phosphatidylcholine lipid,which are assembled onto the surface of articular cartilage in a gel *** them,brush-like biomacromolecules or assemblies have a vital effect on human joint *** by this,the combination of brush-like molecular structures and gel-like assembly may be an efficient approach for the synthesis of biomimetic lubricating *** from the lubrication system of human joints,poly(2-methacryloyloxyethyl phosphorylcholine)(PMPC)brushes grafted poly(N-isopropylacrylamide-co-acrylic acid)(poly(NIPAAm-co-AA))microgels,abbreviated as MBs-g-MGs,were synthesized as one kind of biomimetic lubricating *** is worth noting that this bionic strategy considered both molecular structure and assembled form,which enabled this hairy microgel to achieve low friction in aqueous ***,the effective lubrication was still achieved when using MBs-g-MGs at high temperature,indicating that this microgel maintains a good lubricating effect over a wide range of *** addition,this kind of microgel possessed good biocompatibility,which laid the foundation for potential biomedical *** beyond,these biomimetic microgels may provide an effective lubricating effect for water-based sliding interfaces,especially in biomedical systems.