检索结果-南通市图书馆

Enhance Stability and in vitro Cell Response to a bioinspired coating on Zr Alloy with Increasing Chitosan Content

Journal of Bionic Engineering 2017年第3期14卷 459-467页

作者： Daniela Ionita Maria Vardaki Miruna S. Stan Anca Dinischiotu Ioana Demetrescu Faculty of Applied Chemistry and Materials Science University Politehnica of Bucharest 1-7 Polizu 011061 Bucharest Romania Department of Biochemistry and Molecular Biology Faculty of Biology University of Bucharest 91-95 Splaiullndependentei 050095 Bucharest Romania Academy of Romanian Scientist Splaiullndependentei 54 050094 Bucharest Romania

The aim of the present paper is to characterize bioinspired chitosan （CS）＋ hydroxyapatite （HA） coatings with various components ratio on a zirconium alloy with titanium. The coatings were characterized by FT-IR, SEM, hydrophilic/hydrophobic balance, adherence, roughness, electrochemical stability and in vitro cell response. Electrochemical tests, including potentio- dynamic polarization curves and electrochemical impedance spectroscopy, were performed in normal saline physiological solution. Cell viability of MC3T3-E1 osteoblasts, lactate dehydrogenase, nitric oxide, and Reactive Oxygen Species （ROS） levels, as well as actin cytoskeleton morphology, were evaluated as biological in vitro tests. The results on in vitro cell response indicated good cell membrane integrity and viability for all samples, but an increased cell number, a decreased ROS level and a better cytoskeleton organization were noticed for the sample with a higher CS content. The coating with highest CS concen- tration indicated the best performance based on the experimental data. The highest hydrophilic character, highest resistance to corrosion and best biocompatibility as well recommend this coating for bioapplications in tissue engineering.

关键词： ZrTi alloy bioinspired coating cells response electrochemical stability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

bioinspired Hollow Mesoporous Silica Nanoparticles coating on Titanium Alloy with Hierarchical Structure for Modulating Cellular Functions

引用

Journal of Bionic Engineering 2024年第3期21卷 1427-1441页

作者： Jiaxin Zhang He Liu Jincheng Wang Jing Shang Mingwei Xu Xiujie Zhu Chao Xu Haotian Bai Xin Zhao Orthopedic Institute of Jilin Province Orthopedic Medical CenterThe Second Hospital of Jilin UniversityChangchun130041China Key Laboratory of Bionic Engineering(Ministry of Education) Jilin UniversityChangchun130025China Institute of Structured and Architected Materials Liaoning Academy of MaterialsShenyang110167China

3D-printed Porous Titanium Alloy Implants(pTi),owing to their biologically inertness and relatively smooth surface morphology,adversely affect the biological functions of surrounding *** address the challenges,constructing a bioinspired interface that mimics the hierarchical structure of bone tissue can enhance the cellular functions of *** this context,Hollow Mesoporous Silica Nanoparticles(HMSNs),renowned for their unique physicochemical properties and superior biocompatibility,offer a promising direction for this *** this research,the initially synthesized HMSNs were used to construct a“hollow-mesoporous-macroporous”hierarchical bioinspired coating on the pTi surface through the Layer-by-Layer ***,diverse morphologies of coatings were established by adjusting the deposition strategy of PDDA/HMSNs on the pTi surface(pTi-HMSN-2,pTi-HMSN-4,pTi-HMSN-6).A range of techniques were employed to investigate the physicochemical properties and regulation of cellular biological functions of the diverse HMSN coating ***,the pTi-HMSN-4 and pTi-HMSN-6 groups exhibited the uniform coatings,leading to a substantial enhancement in surface roughness and ***,the coating constructed strategy of pTi-HMSN-4 possessed commendable *** on the aforementioned findings,both pTi-HMSN-4 and pTi-HMSN-6 facilitated the adhesion,spreading,and pseudopodia extension of BMSCs,which led to a notable upsurge in the expression levels of vinculin protein in *** analysis indicates that the coating,when PDDA/HMSNs are deposited four times,possesses favorable overall *** research will provide a solid theoretical basis for the translation of HMSN bioinspired coatings for orthopedic implants.

关键词： Hollow mesoporous silica nanoparticles bioinspired coating Titanium alloy Hierarchical structure Cellular functions

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：