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Neoadjuvant targeted therapy for apocrine carcinoma of the breast:A case report

World Journal of Clinical Cases 2020年第23期8卷 6036-6042页

作者： Ping Yang Shu-Jia Peng Yan-Ming Dong Lin Yang Zhen-Yu Yang Xi-E Hu Guo-Qiang Bao Department of General Surgery Tangdu HospitalAir Force Military Medical UniversityXi’an 710032Shaanxi ProvinceChina

BACKGROUND apocrine carcinoma of the breast is a special type of invasive ductal carcinoma of the breast that is rare in clinical *** therapy,especially neoadjuvant targeted therapy,has rarely been reported for apocrine carcinoma of the *** SUMMARY A 63-year-old woman presented with apocrine carcinoma of the left breast underwent core needle *** patient was diagnosed with apocrine carcinoma by immunohistochemical staining and negative hormone status(estrogen receptor and progesterone receptor)but showed overexpression of human epidermal factor receptor 2(HER-2).Moreover,positive expression of androgen receptor(approximately 60%)and gross cystic disease fluid protein 15 was *** patient was treated with neoadjuvant targeted therapy consisting of the TCH regimen(docetaxel,carboplatin area under curve 6 and trastuzumab)every 21 *** mass in the left breast was significantly reduced,and pain in the breast and left upper arm also *** HER-2 positive apocrine carcinoma of the breast can be improved by neoadjuvant chemotherapy combined with targeted therapy.

关键词： Breast neoplasm ErbB-2 receptor Targeted therapy Case report apocrine gland Neoadjuvant therapies

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A Case of Congenital Syringocystadenoma Papilliferum

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Chinese Journal of Plastic and Reconstructive Surgery 2021年第2期3卷 79-81页

作者： Liansheng ZHONG Meilian LIU Xingqiang GAO Department of Dermatology Xiamen Children’s HospitalXiamenFujian 361006China Department of Pathology Xiamen Children’s HospitalXiamenFujian 361006China Department of Otolaryngology and Head and Neck Surgery Xiamen Children’s HospitalXiamenFujian 361006China

Syringocystadenoma papilliferum(SCAP)is a rare benign skin tumor that develops from the apocrine or eccrine ***,we report the case of a 2-year-old girl who presented with an asymptomatic,slowly growing lesion on her *** physical examination,a 2 cm×1 cm red papillary plaque with a crusted surface was noted on her ***pathological examination revealed papillomatous expansion of the epidermis and cystic invaginations extending from the epidermis down to the deep *** cystic structures were lined by papillae with two layers of columnar epithelium,which showed decapitation *** on the above clinicopathological findings,a diagnosis of congenital scalp SCAP was made.

关键词： Syringocystadenoma papilliferum Congenital apocrine gland Eccrine gland

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