Neoadjuvant targeted therapy for apocrine carcinoma of the breast:A case report
作者机构：Department of General SurgeryTangdu HospitalAir Force Military Medical UniversityXi’an 710032Shaanxi ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2020年第8卷第23期
页 面：6036-6042页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Breast neoplasm ErbB-2 receptor Targeted therapy Case report Apocrine gland Neoadjuvant therapies
摘 要：BACKGROUND Apocrine carcinoma of the breast is a special type of invasive ductal carcinoma of the breast that is rare in clinical *** therapy,especially neoadjuvant targeted therapy,has rarely been reported for apocrine carcinoma of the *** SUMMARY A 63-year-old woman presented with apocrine carcinoma of the left breast underwent core needle *** patient was diagnosed with apocrine carcinoma by immunohistochemical staining and negative hormone status(estrogen receptor and progesterone receptor)but showed overexpression of human epidermal factor receptor 2(HER-2).Moreover,positive expression of androgen receptor(approximately 60%)and gross cystic disease fluid protein 15 was *** patient was treated with neoadjuvant targeted therapy consisting of the TCH regimen(docetaxel,carboplatin area under curve 6 and trastuzumab)every 21 *** mass in the left breast was significantly reduced,and pain in the breast and left upper arm also *** HER-2 positive apocrine carcinoma of the breast can be improved by neoadjuvant chemotherapy combined with targeted therapy.
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