检索结果-南通市图书馆

Correlation between age of onset and gastrointestinal stenosis in hospitalized patients with Crohn's disease

World Journal of Clinical Cases 2020年第13期8卷 2769-2777页

作者： Shan-Bing Yang Shu-Wen Du Ji-Heng Wang Department of Gastroenterology the Seventh Medical CenterChinese People’s Liberation Army General HospitalBeijing 100700China

BACKGROUND Patients affected by Crohn's disease(CD)are more likely to develop gastrointestinal stenosis and often undergo surgery during the duration of *** To identify the risk factors for gastrointestinal stenosis in hospitalized CD patients in *** The clinical data of CD patients hospitalized at the Seventh Medical Center,Chinese People's Liberation Army General Hospital from January 2010 to December 2018 were *** with gastrointestinal stenosis were compared to those without gastrointestinal stenosis for clinical *** risk factors for gastrointestinal stenosis were identified using univariate and multivariable logistic regression *** treatments for patients with gastrointestinal stenosis were analyzed,and the characteristics of different treatment methods were *** The incidence of gastrointestinal stenosis was 59.02%in the 122 hospitalized CD *** of onset of more than 40 years(odds ratio[OR]=3.072,95%confidence interval[CI]:1.298-7.272,P=0.009)and duration of disease of more than 5 years(OR=2.101,95%CI:1.002-4.406,P=0.048)were associated with the occurrence of gastrointestinal ***(20.83%)patients did not undergo surgery and received internal medicine and nutrition *** treatments were performed in 72.22%(52)of *** rate of postoperative complications was 15.38%(8 cases),and during a median follow-up period of 46 mo,11.54%(6 cases)underwent reoperation.A total of 29.17%(21 cases)were treated with endoscopic therapy,and during a median follow-up period of 32 mo,76.19%(16 cases)had no surgical event,23.81%(5 cases)failed to avoid surgical treatments,and no serious postoperative complications occurred after endoscopic *** age of onset of more than 40 years and duration of disease of more than 5 years may be strongly correlated with a higher risk of gastrointestinal stenosis in hospitalized CD *** therapy for gastrointestinal stenosis

关键词： Crohn's disease Gastrointestinal stenosis age of onset Duration of disease Endoscopy Surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of nape acupuncture combined with swallowing rehabilitation on dysphagia in pseudobulbar palsy

引用

Journal of Traditional Chinese Medicine 2018年第1期38卷 117-124页

作者： Liu Xiaoping Chen Feiyu Chu Jiamei Bao Yehua Department of Acupuncture-Moxibustion and Rehabilitation Hangzhou Hospital of Traditional Chinese Medicine

OBJECTIVE: To evaluate the therapeutic effects of nape acupuncture combined with rehabilitative swallowing training for dysphagia caused by pseudobulbar palsy, and to compare it with rehabilitative swallowing training alone, and to observe the improvement in quality of life after the ***: One hundred patients were randomly divided into two groups: the rehabilitative swallowing training group(control group, n = 50) and the nape acupuncture combined with rehabilitative swallowing training group(experimental group,n = 50). Each group had 8 weeks' therapy, 5 times a week. Patients in the control group received rehabilitative swallowing training, while those in the experimental group received nape acupuncture therapy based on swallowing rehabilitation. The out-comes were assessed by the repetitive saliva-swallowing test(RSST), water swallow test(WST), standardized swallowing assessment(SSA), and a swallow quality-of-life questionnaire(SWAL-QOL). Correlations of onset age, onset frequency and lesion location with the efficacy of the acupuncture treatment were also ***: The scores for RSST, WST, and SSA in both groups were lower than before the therapy(P 0.05), but was related to onset age(P onset frequency(P < 0.01).CONCLUSION: Nape acupuncture combined with rehabilitative swallowing training has an effect on dysphagia caused by pseudobulbar palsy and improves quality of life.

关键词： Deglutition disorders Pseudobulbar palsy Quality of life age of onset Nape acupunc- ture Rehabilitative swallowing training

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis

引用

World Journal of Diabetes 2022年第3期13卷 260-271页

作者： Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant Diabetes Research Centre University of LeicesterLeicester General HospitalLeicester LE54PWUnited Kingdom Department of Cardiovascular Sciences Glenfield HospitalUniversity of LeicesterLeicester LE39QPUnited Kingdom The Hanning Sleep Laboratory University Hospitals of Leicester NHS TrustUniversity of LeicesterLeicester LE54PWUnited Kingdom National Institute for Health Research Leicester Biomedical Research CentreLeicester LE54PWUnited Kingdom Leicester Diabetes Centre University Hospitals of Leicester NHS TrustLeicester LE54PWUnited Kingdom National Institute for Health Research Applied Research Collaboration East MidlandsLeicester LE54PWUnited Kingdom Department of Diabetes University Hospitals of Derby and Burton NHS Foundation TrustDerby DE223NEUnited Kingdom

BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger *** To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with *** A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 *** and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood *** and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk *** A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in *** diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older *** results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other *** age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and *** The diagnosis of T2D earlier in life is associated with a worse cardi

关键词： Type 2 diabetes mellitus Early-onset adult type 2 diabetes age of onset Cardiovascular risk Young adults Glycaemic control Obesity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of age and tumor size on the development of the Kasabach-Merritt phenomenon in patients with kaposiform hemangioendothelioma:a retrospective cohort study

引用

Precision Clinical Medicine 2023年第2期6卷 81-88页

作者： Jiangyuan Zhou Yuru Lan Tong Qiu Xue Gong Zixin Zhang Chunshui He Qiang Peng Fan Hu Xuepeng Zhang Guoyan Lu Liqing Qiu Feiteng Kong Yongbo Zhang Siyuan Chen Yi Ji Division of Oncology Department of Pediatric SurgeryWest China Hospital of Sichuan UniversityChengdu 610041China Department of Vascular Surgery University Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610032China Department of Pediatric Surgery Chengdu Women and Children’s Central HospitalChengdu 610073China Department of Vascular&Interventional Radiology West China Second University HospitalSichuan UniversityChengdu 610044China Department of Pediatrics West China Second University HospitalSichuan UniversityChengdu 610044China Department of Pediatric Surgery Chengdu Shangjin Nanfu HospitalChengdu 611730China Department of Pediatric Surgery Sichuan Women and Children’s HospitalChengdu 610036China Pediatric Intensive Care Unit Department of Critical Care MedicineWest China Hospital of Sichuan UniversityChengdu 610041China

Introduction The Kasabach–Merritt phenomenon(KMP)is a severe complication of kaposiform hemangioendothelioma(KHE).The risk factors for KMP need further *** The medical records of patients with KHE were *** and multivariate logistic regression models were used for the risk factors for KMP,and the area under the receiver operator characteristic(ROC)curve was used to assess the predictive power of risk *** A total of 338 patients with KHE were *** incidence of KMP was 45.9%.age of onset(Page of onset(Page of onset,treatments,and hematological *** an onset age of 4.75 months as a cutoff,we found significant differences in tumor morphology,lesion size,hematological parameters,and *** For KHE patients with an onset age5.35 cm,clinicians should be wary of the occurrence of *** management is recommended to improve the prognosis.

关键词： kaposiform hemangioendothelioma Kasabach-Merritt phenomenon age of onset tumor size cutoff values

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

TNF-α-1031 T/C polymorphisms is associated with cognitive dysfunction in chronic schizophrenia

TNF-α-1031 T/C polymorphisms is associated with cognitive d...

引用

浙江省神经科学学会第五届学术年会

作者：唐伟 Cheng Zhu Ke Zheng Na Wen Jian-She Pan Jia-Hong Liu Mei-Hong Xiu 中国医院协会民营分会

Objective:To explore the association of TNF-α-1031 T/C polymorphism and age of onset and cognitive ***:We recruit486 inpatients with schizophrenia and 310 age-,sex-and education matched healthy *** functions were measured by RBANS and symptoms were assessed by *** TNF-α-1031 T/C polymorphisms were measured by ***:There were no significant differences in allelic frequency and genotype frequency of TNF-α-1031 T/C polymorphism between patients and normal controls,but a significant association with age of onset(F=7.321,P=0.007) and significant associations with immediate memory,visuospatial,total score of RBANS(F=9.140,P=0.003;F=6.742,P=0.010;F=8.331,P=0.004).The age of onset was related to attention,immediate memory,delayed memory and total score of RBANS(r=0.179,P=0.002;r=0.102,P=0.041;r=0.154,P=0.008;r=0.134,P=0.021).It is significant for the mediation analysis for the relationship across TNF-α-1031 T/C polymorphism,age of onset and cognitive ***:Our results suggested that TNF-α-1031 T/C plays a role in cognitive impairments,age of onset and their association in chronic patients with schizophrenia.

关键词： schizophrenia polymorphisms cognitive dysfunction age of onset

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

食管癌高发区贲门癌,胃癌流行强度分析(英文)

食管癌高发区贲门癌,胃癌流行强度分析(英文)

引用

第五届全国中医药免疫学术研讨会——暨环境·免疫与肿瘤防治综合交叉会议

作者： WEN Denggui,WANG Shijie,ZHANG Liwei,Wang Xiaolin,WEI Lizhen,ZHOU Wendi,QIN Peng Epidemiology,The Fourth Hospital of Hebei Medical University,Hebei Medical Universi Shijiazhuang

Obejective:The familial aggregation of esophageal squamous cell carcinoma(ESCC) epidemiologically observed in the northern Chinese high-risk region may be argued to reflect either genetic predisposition or common household *** some molecular evidences such as single nucleartide polyphorphism is available which suggest the existence of genetic predisposition for ESCC,there is a lack of clear pathoclinical data supporting *** demonstrate the effect of inherited predisposition for familial esophageal squamous cell carcinoma cases as opposed to the sporadic counterpart,this article analysed the clinicopathological differences in onset age,prevalence of double primary malignancy,and long-term post-surgical survival rates between familial and sporadic ***:Differences in age of onset,prevalence rates of double primary ESCC,and survival rates were analyzed between the familial(N=476) and sporadic ESCC cases(N=1226).T-test is used to test the difference in onset ages, and Chi-square test is employed to examine the different prevalence rates of double primary *** difference in long-trem survival rates between the familial and the sporadic cases is analysed with the Cox propotional Hazard ***:Overall,familial ESCC cases show a significantly earlier onset age(51.9±8.2 versus 53.4±8.0 years old,P=0.00),a significantly higher prevalence rate of double ESCC(2.73%Versus 1.22%,adjusted with TNM:X=4.029,P=0.045),and a lower survival curve than the sporadic cases(P=0.04).The familial cases showed both earlier onset and poor survival at most subgroups,and the differences were bigger in early-stage than in late-stage ***: Because only an inherited genetic alteration would greatly increase the chance of double primary malignancies,our findings about a early onset,more double primary malignancies,and poor prognosis for the familial as apposed to the sporadic cases suggest the existence of such an inherited genetic alteration in the

关键词： Esophageal Squamous Cell Carcinoma Familial Cancer age of onset Synchronous Primary Carcinoma Prognosis Sporadic Cancer

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：