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ACT、TED算法基于MILP搜索的积分分析

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小型微型计算机系统 2022年第9期43卷 1976-1983页

作者：熊家琪袁征魏锦鹏刘宗甫朱亮北京电子科技学院密码与科学技术系北京100070 西安电子科技大学通信工程学院西安710071

ACT和TED算法是近年来相继被提出的,分别基于SPN结构和Feistel结构而设计的两种轻量级分组密码算法.本文根据这两种算法不同的结构特性,分别构建了相关的基于比特可分性的MILP模型,并调用求解工具Gurobi对MILP模型进行求解.实验结果表明... 详细信息

ACT和TED算法是近年来相继被提出的,分别基于SPN结构和Feistel结构而设计的两种轻量级分组密码算法.本文根据这两种算法不同的结构特性,分别构建了相关的基于比特可分性的MILP模型,并调用求解工具Gurobi对MILP模型进行求解.实验结果表明:ACT和TED算法都存在8、9、10轮积分区分器,另外TED算法还存在7轮积分区分器.根据所搜索到的积分区分器,实现了两种算法的11轮密钥恢复攻击方案.利用ACT算法的9轮积分区分器向后扩展2轮进行11轮的密钥恢复攻击时,攻击数据复杂度为2^(36.39),时间复杂度为2^(36.39)次11轮加密,存储复杂度为2^(20).利用TED算法的8轮积分区分器向后扩展3轮进行11轮的密钥恢复攻击时,数据复杂度为2^(60.81),时间复杂度为2^(109.54)次11轮加密,存储复杂度为2^(59).

关键词：轻量级分组密码算法 ACT TED 可分性积分分析 MILP(混合线性整数规划)

Pluripotent stem cell derived inhibitory interneurons–principles and applications in health and disease

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Neural Regeneration Research 2020年第2期15卷 251-252页

作者： Francesca Keefe Meng Li Neuroscience and Mental Health Research Institute School of Medicine and School of Bioscience Cardiff University

Inhibitory interneurons are gamma-aminobutyric acid-ergic (GABAergic) nerve cells that ACT to maintain the appropriate excitation-inhibition balance, and synchronise the output of principle cells to generate rhythmic patterns of firing (Kessaris et al., 2014). This critical role, along with their brain-wide distribution, has led to the implication of interneurons in many neuropathologies, including schizophrenia, autism, dystonia and epilepsies (Marín, 2012).

关键词： cells ACT has led

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虚拟生存经验与中国网络文学的起点

中国图书评论 2024年第2期 82-88页

作者：汪希华中师范大学文学院

中国网络文学的起点问题关乎对其本质属性的认定,使其能与传统文学和西方网络文学区分开来。从网络社会出发,虚拟性、虚拟经验或许是探寻网络文学起点的重要角度。虚拟生存体验构成了网络文学与传统文学、西方电子文学的重要区别。在虚... 详细信息

中国网络文学的起点问题关乎对其本质属性的认定,使其能与传统文学和西方网络文学区分开来。从网络社会出发,虚拟性、虚拟经验或许是探寻网络文学起点的重要角度。虚拟生存体验构成了网络文学与传统文学、西方电子文学的重要区别。在虚拟生存体验中,交往性(数字交往/虚拟交往)是重要方面。可以发现,虚拟交往是贯穿于网络文学发展始终的一条线索与推动力,不仅构成其外部活动特征,也改造了其内在文本结构。从交往性出发,1993年海外华文网络文学的ACT可被看作中国网络文学的起点。

关键词：虚拟生存体验中国网络文学起点交往性 ACT

The histone acetyltransferase MOF is required for the cellular stress response

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Science Bulletin 2017年第23期62卷 1559-1561页

作者： Yang Yang Xiaofei Han Jing Hea Xinghong Guo Abdul Sami Shaikh Lichao Sun Shuang Gao Yiran Liang Meng Wang Xiangzhi Li The Key Laboratory of Experimental Teratology Ministry of Education and Department of Cell and Neurobiology Shandong University School of Basic Medicine Jinan 250012 China Institute of Clinical Pharmacology Qilu Hospital of Shandong University Jinan 250012 China State Key Laboratory of Molecular Oncology Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China

When exposing to environmental stress or internal damage,such as genotoxic stress,oxidative stress,and heat stress,cells produce a series of adaptive responses called cellular stress responses[1].The major proteins involved in cellular stress are heat shock proteins(HSPs).HSPs remain in a low expression level and display a diffused distribution in the nucleoplasm and cytoplasm under basal conditions.In response to various stress conditions。

关键词： MOF The histone acetyltransferase MOF is required for the cellular stress response HSF ACT

隐性认知风格对高中生抑郁的影响：心理僵化的作用及干预研究

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隐性认知风格对高中生抑郁的影响：心理僵化的作用及干预研究

作者：代玲燕云南师范大学

学位级别：硕士

青少年抑郁情绪问题近年来已经引起了社会各界的广泛关注。抑郁不仅会给学生带来心理问题和躯体危害,而且导致了很多家庭和社会问题,因而预防和干预青少年抑郁有着深远的意义。教育部、国家卫健委等部门已将预防抑郁教育视为保障青少年... 详细信息

青少年抑郁情绪问题近年来已经引起了社会各界的广泛关注。抑郁不仅会给学生带来心理问题和躯体危害,而且导致了很多家庭和社会问题,因而预防和干预青少年抑郁有着深远的意义。教育部、国家卫健委等部门已将预防抑郁教育视为保障青少年身心健康的重要工作。学界也对青少年抑郁展开了系列研究,在对抑郁形成原因的众多解释中,抑郁认知理论指出,抑郁与认知偏差密切相关,抑郁者容易出现夸大或缩小、极端思维等认知偏差。其中,隐性认知风格作为个体面对消极事件时产生的认知偏差,就是指个体容易夸大评估威胁并认为威胁在逐渐逼近,导致个体产生抑郁等消极情绪及消极认知,并多以认知或行为回避作为自我保护和应对策略。长期的消极想法和回避行为会使个体形成稳定的否定性图示,无法聚焦当下获得真实信息,身心不能灵活地适应变化的情景,缺乏动力性适应,即出现心理僵化。由此可见,隐性认知风格和心理僵化很可能相互影响并形成恶性循环,进而给个体带来沉重的精神压力和痛苦,加重抑郁。故而,本研究从隐性认知风格、心理僵化与抑郁情绪的关系入手,一方面探讨高中生抑郁情绪的影响因素及其机制,另一方面运用接纳承诺疗法(ACT)从心理僵化入手为预防和干预青少年抑郁提供方法和建议。为探索高中生抑郁和隐性认知风格、心理僵化之间的关系及ACT干预的有效性,本研究分为两部分:第一部分采用《隐性不适应风格问卷》、《抑郁自评量表》、《中文版接纳行动问卷》和《中文版认知融合问卷》,对云南省两所学校的725名高中生进行调查,探讨隐性认知风格、心理僵化与抑郁三者间的关系及心理僵化的中介作用;第二部分为高中生心理僵化的干预研究,基于研究一的量化结果及接纳承诺疗法(ACT)的理论,设计实施提升心理灵活性(即降低心理僵化)为主题的团辅方案,通过收集干预对象的前后测数据,探究ACT团体辅导对提升高中生心理灵活性、改善抑郁的有效性。研究结论如下:1.本研究所调查的高中生一半以上(68.6%)存在不同程度的抑郁情绪,其中存在中重度抑郁情绪的学生占比超一半(37%),并且高中生抑郁情绪在性别、年级上存在显著差异,女生的抑郁水平显著高于男生;高二年级抑郁情况较为突出。2.本研究所调查的高中生隐性认知风格得分总体偏高,说明不少学生面对消极事件倾向于高估其威胁并认为风险在快速增长。并且高中生隐性认知风格在性别和年级上存在显著差异,面对消极事件女生比男生更倾向于高估其风险;高二年级的学生隐性认知风格水平较高。3.本研究中所调查的高中生心理僵化程度普遍较高,说明高中生心理灵活性较低。并且高中生心理僵化在性别、年级、家庭居住地上存在显著差异,除了女生、高二年级心理僵化程度较高之外,生源地是城市的学生心理僵化得分高于农村的学生。4.高中生抑郁情绪、隐性认知风格、心理僵化之间两两呈显著的正相关关系,隐性认知风格、心理僵化能显著预测抑郁情绪。并且心理僵化在隐性认知风格及抑郁间起中介作用,隐性认知风格不仅能直接影响抑郁,还能通过心理僵化间接影响抑郁。5.本研究设计实施的ACT团体辅导干预具有一定的有效性,因此通过干预高中生心理僵化,提升高中生心理灵活性,能有效缓解抑郁情绪。

关键词：抑郁情绪隐性认知风格心理僵化 ACT 团体心理辅导

A Three-Dimensional Mn^Ⅱ-[Mo^Ⅲ(CN)7]^4-Ferrimagnet Containing Formate as a Second Bridging Ligand

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Chinese Journal of Chemistry 2019年第1期37卷 19-24页

作者： Le Shi Dong Shao Fu-Ying Shen Xiao-qin Wei Xin-Yi Wang State Key Laboratory of Coordination Chemistry Collaborative Innovation Center of Advanced MicrostructuresSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjingJiangsu 210023China

Summary of main observation and conclusion Serf-assembly of the [Mo(CN)7]^4-anion and the Mn^2+ ion in the aqueous solution containing ammonium formate results in a new coordination polymer,{(NH4)3[(H2O)Mn3(HCOO)][Mo(CN)7]2·4H2O}n.Single crystal X-ray analysis revealed a very complicated three-dimensional (3D)framework,where both the [Mo(CN)7]^4- and the formate anions ACT as bridges between the Mn^Ⅱ centers.Magnetic measurements revealed that this compound displays ferrimagnetic ordering below 70 K.Competing antiferromagnetic interACTions between the spin carriers might lead to spin frustration and non-linear alignment of the magnetic moments.Specifically,this compound is the first mixed [Mo(CN)7]^4-/HCOO^- bridged molecule magnet.

关键词： Mn^2+ frustration spin X-ray ACT

Mandated health insurance increases rates of elective knee surgery

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World Journal of Orthopedics 2019年第2期10卷 81-89页

作者： Daniel Kim Woo Do Shahein Tajmir Brandon Mahal Joe DeAngelis Arun Ramappa Radiation Oncology Massachusetts General Hospital Harvard Medical School Department of Surgery Madigan Army Medical Center Radiology Massachusetts General Hospital Harvard Medical School Department of Orthopaedic Surgery Beth Israel Deaconess Medical Center Harvard Medical School

BACKGROUND The recent federal ruling to against Affordable Care ACT(ACA), specifically the mandate requiring people to buy insurance, has once again brought the healthcare reform debate to the spotlight. The ACA increased the number of insured Americans through the development of subsidized healthcare plans and health insurance exchanges. Insurance-based differences in the rate of upper extremity elective orthopaedic surgery have been described before and after healthcare reform in Massachusetts, where a similar mandate was put into place years before the ACA was passed. However, no comprehensive study has evaluated insurance-based differences of knee elective surgery before and after reform.AIM To investigate how an individual mandate to purchase health insurance affects rates of knee surgery.METHODS A retrospective review was performed within an orthopaedic surgery department at a tertiary-care, academic medical center in Massachusetts. The rate of elective knee surgery performed before and after the healthcare reform(2005-2006 and 2007-2010, respectively) was calculated. The patients were categorized by insurance type(Commonwealth Care, Medicare, Medicaid, private insurance,Workers' Compensation, TriCare, and Uninsured). Using χ2 testing, differences in rates of surgery between the pre-reform and post-reform period and among insurance subgroups were calculated.RESULTS Rate of surgery increased in the post-reform period(pre-reform 8.07%(95%CI:7.03%-9.11%), post-reform 9.38%(95%CI: 8.74%-10.03%)(P = 0.04) and was statistically significant. When the insurance groups and insurance types were compared, the rates of surgery are not significantly different before or after reform.CONCLUSION The increase in the rate of elective knee surgery in the post-reform period suggests that health care reform in Massachusetts has been successful in decreasing the uninsured population and may increase health care expenditures.This is a hypothesis generating study that suggests further avenues of study on how mandated coverage may

关键词： Healthcare reform Elective surgery Lower extremity Affordable Care ACT Orthopaedic surgery

Differences between British and Japanese perspectives on forensic mental health systems:A preliminary study

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World Journal of Psychiatry 2017年第1期7卷 8-11页

作者： Akihiro Shiina Aika Tomoto Soichiro Omiya Aiko Sato Masaomi Iyo Yoshito Igarashi Division of Medical Treatment and Rehabilitation Chiba University Center for Forensic Mental Health Division of Law and Psychiatry Chiba University Center for Forensic Mental Health Social Psychiatry and Mental Health Faculty of MedicineUniversity of Tsukuba Chiba University Graduate School of Medicine

AIM To clarify the differences in views on forensic mental health(FMH) systems between the United Kingdom and Japan.METHODS We conducted a series of semi-structured interviews with six leading forensic psychiatrists. Based on a discussion by the research team, we created an interview form. After we finished conducting all the interviews, we qualitatively analyzed their content. RESULTS In the United Kingdom the core domain of FMH was risk assessment and management; however, in Japan, the core domain of FMH was psychiatric testimony. In the United Kingdom, forensic psychiatrists were responsible for ensuring public safety, and psychopathy was identified as a disease but deemed as not suitable for medical treatment. On the other hand, in Japan, psychopathy was not considered a mental illness. CONCLUSION In conclusion, there are considerable differences between the United Kingdom and Japan with regard to the concepts of FMH. Some ideas taken from both cultures for better FMH prACTice were suggested.

关键词： Forensic mental health Medical treatment and supervision ACT Psychopathy International comparison Qualitative research

Prolonged overall survival in gastric cancer patients after adoptive immunotherapy

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World Journal of Gastroenterology 2015年第9期21卷 2777-2785页

作者： Guo-Qing Zhang Hong Zhao Jian-Yu Wu Jin-Yu Li Xiang Yan Gang Wang Liang-Liang Wu Xiao-Gang Zhang Yi Shao Yu Wang Shun-Chang Jiao Department of Clinical Oncology Chinese PLA General Hospital Laboratory of Tumor Research Center Chinese PLA General Hospital Beijing Immunotech Applied Science Limited

AIM:To assess the efficacy of immunotherapy with expanded ACTivated autologous lymphocytes(EAALs) in gastric cancer.METHODS:An observational study was designed to retrospectively analyze the clinical data of 84 gastric cancer patients,of whom 42 were treated by EAAL immunotherapy plus conventional treatment and another 42 only received conventional treatment(control group).EAALs were obtained by proliferation of peripheral blood mononuclear cells from patients followed by phenotype determination.Clinical data including age,gender,clinical stage,chemotherapeutic regimens,hospitalization,surgical,radiotherapy,and survival data were collected along with EAAL therapy details and side effects.Patients were followed and the relationship between treatment and overall survival(OS) data obtained for the immunotherapy and control groups were compared retrospectively.The safety of EAAL immunotherapy was also evaluated.RESULTS:After in vitro culture and proliferation,the percentages of CD3+,CD3+CD8+,CD8+CD27+,CD8+CD28+,and CD3+CD16+/CD56+cells increased remarkably(P ACTors for gastric cancer patients.Indeed,the OS in stage Ⅲc and Ⅳ patients that had received surgery was prolonged after EAAL immunotherapy(P < 0.05).Importantly,in vitro induction and proliferation of EAAL were easy and biologically safe.CONCLUSION:Overall,EAAL adoptive immunotherapy might prolong the OS in gastric cancer patients.

关键词： Adoptive immunotherapy Gastric cancer Expanded ACT