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Emerging wet electrohydrodynamic approaches for versatile bioactive 3d interfaces

Nano Research 2020年第2期13卷 315-327页

作者： Mehmet Berat Taskin Lasse Hyldgaard Klausen Mingdong dong Menglin Chen department of Engineering Aarhus University8000 Aarhus CDenmark Interdisciplinary Nanoscience Center Aarhus University 8000 Aarhus CDenmark

There is a compelling need for delicate nanomaterial design with various intricate functions and *** applies electrostatic force to overcome the surface tension of a liquid jet,shrinking the jet through intrinsic jetting instabiity into submicron fibers or spheres,with versatilty from a huge selection of materials,feasibllity of extracellular matrix structure mimicry and multicompartmentalization for tissue engineering and drug *** process typically involves the collection and drying of fibers at a solid substrate,but the introduction of a liquid phase collection by replacing the solid collector with a coagulation bath can introduce a variety of new opportunities for both chemical and physical functionalizations in one single *** so-called wet electrohydrodynamics is an emerging technique that enables a facile,homogeneous functionalization of the intrinsic large surface area of the submicron fibers/*** a thorough literature sweep,we herein highlight the three main engineering features integrated through the single step wet electrospinning process in terms of creating functional biomaterials:(i)The fabrication of 3d macrostructures,(ii)in situ chemical functionalization,and(iii)tunable *** an emerging technique,wet electrohydrodynamics has demonstrated a great potential in interdisciplinary research for the development of functional 3d interfaces and materials with pertinent applications in all fields where secondary structured,functional surface is *** these,engineered biomaterials bridging materials science with biology have already shown particular potential..

关键词： wet-electrohydrodynamics 3d macrostructure in-situ functionalization nanotopographical alteration tissue engineering nanotechnology

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