Emerging wet electrohydrodynamic approaches for versatile bioactive 3D interfaces

作     者：Mehmet Berat Taskin Lasse Hyldgaard Klausen Mingdong Dong Menglin Chen Mehmet Berat Taskin;Lasse Hyldgaard Klausen;Mingdong Dong;Menglin Chen

作者机构：Department of EngineeringAarhus University8000 Aarhus CDenmark Interdisciplinary Nanoscience Center Aarhus University8000 Aarhus CDenmark 

出 版 物：《Nano Research》 (纳米研究（英文版）)

年 卷 期：2020年第13卷第2期

页      面：315-327页

核心收录：

学科分类：0808[工学-电气工程] 0809[工学-电子科学与技术（可授工学、理学学位）] 080704[工学-流体机械及工程] 080103[工学-流体力学] 08[工学] 0807[工学-动力工程及工程热物理] 0805[工学-材料科学与工程（可授工学、理学学位）] 0702[理学-物理学] 0801[工学-力学（可授工学、理学学位）] 

基　　金：We gratefully acknowledge the funding from Aarhus University Research Foundation(AUFF-E-2015-FLS-7-27) 

主　　题：wet-electrohydrodynamics 3D macrostructure in-situ functionalization nanotopographical alteration tissue engineering nanotechnology 

摘      要：There is a compelling need for delicate nanomaterial design with various intricate functions and *** applies electrostatic force to overcome the surface tension of a liquid jet,shrinking the jet through intrinsic jetting instabiity into submicron fibers or spheres,with versatilty from a huge selection of materials,feasibllity of extracellular matrix structure mimicry and multicompartmentalization for tissue engineering and drug *** process typically involves the collection and drying of fibers at a solid substrate,but the introduction of a liquid phase collection by replacing the solid collector with a coagulation bath can introduce a variety of new opportunities for both chemical and physical functionalizations in one single *** so-called wet electrohydrodynamics is an emerging technique that enables a facile,homogeneous functionalization of the intrinsic large surface area of the submicron fibers/*** a thorough literature sweep,we herein highlight the three main engineering features integrated through the single step wet electrospinning process in terms of creating functional biomaterials:(i)The fabrication of 3D macrostructures,(ii)in situ chemical functionalization,and(iii)tunable *** an emerging technique,wet electrohydrodynamics has demonstrated a great potential in interdisciplinary research for the development of functional 3D interfaces and materials with pertinent applications in all fields where secondary structured,functional surface is *** these,engineered biomaterials bridging materials science with biology have already shown particular potential..