检索结果-南通市图书馆

Nanopore-based sensing interface for single molecule electrochemistry

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2019年第12期62卷 1576-1587页

作者： Rui Gao Yao Lin Yi-Lun Ying Yi-Tao Long Department of Chemistry University of UtahSalt Lake CityUtah 84112USA School of Chemistry&Molecular Engineering East China University of Science and TechnologyShanghai 200237China State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China

Nanopore techniques are experiencing a gallop since it walked out the notebook and show its charm on the science *** nanoscale pore offers a single-molecule resolution with a label-free and high-selective manner for the research of molecular structures,molecular dynamics,single-molecule reactions and for a variety of applications in biophysics and *** this review,we introduce the construction of three types of nanopore platforms along with the latest progress in DNA sensing,structure and dynamics analysis of peptides/proteins,and the detection of redox reactions with new sensing ***,we depict nanopore data processing methods which provide an insight of data mining under the background ofbig *** could fully expect the great impact of nanopore techniques on not only for DNA sequencing and sensing applications,but also in protein sequencing and clinical diagnostics.

关键词： nanopore single-molecule sensing nanoelectrochemistry

Pillar effect induced by ultrahigh phosphorous/nitrogen doping enables graphene/MXene film with excellent cycling stability for alkali metal ion storage

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第6期93卷 146-156,I0004页

作者： Meng Qin Yiwei Yao Junjie Mao Chi Chen Kai Zhu Guiling Wang Dianxue Cao Jun Yan Key Laboratory of Superlight Materials and Surface Technology Ministry of EducationCollege of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001HeilongjiangChina Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials and Xiamen Institute of Rare Earth MaterialsHaixi InstituteChinese Academy of SciencesXiamen 361021FujianChina

Graphene's large theoretical surface area and high conductivity make it an attractive anode material for potassium-ion batteries(PIBs).However,its practical application is hindered by small interlayer distance and long ion transfer ***,this paper aims to address the issue by introducing MXene through a simple and scalable method for assembling graphene and realizing ultrahigh P doping *** findings reveal that MXene and P-C bonds have a "pillar effect" on the structure of graphene,and the P-C bond plays a primary *** addition,N/P co-doping introduces abundant defects,providing more active sites for K^(+) storage and facilitating K^(+) *** expected,the developed ultrahigh phosphorous/nitrogen co-doped flexible reduced graphene oxide/MXene(NPrGM) electrode exhibits remarkable reversible discharge capacity(554 mA hg^(-1) at 0.05 A g^(-1)),impressive rate capability(178 mA h g^(-1) at 2 A g^(-1)),and robust cyclic stability(0.0005% decay per cycle after 10,000 cycles at 2 A g^(-1)).Furthermore,the assembled activated carbon‖NPrGM potassium-ion hybrid capacitor(PIHC) can deliver an impressive energy density of 131 W h kg^(-1) and stable cycling performance with 98.1% capacitance retention after5000 cycles at 1 A g^(-1).Such a new strategy will effectively promote the practical application of graphene materials in PIBs/PIHCs and open new avenues for the scalable development of flexible films based on two-dimensional materials for potential applications in energy storage,thermal interface,and electromagnetic shielding.

关键词： Graphene MXene Phosphorous doping Pillar effect Potassium-ion batteries

Amphiphilic block copolymers directed synthesis of mesoporous nickel-based oxides with bimodal mesopores and nanocrystal-assembled walls

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2019年第12期30卷 2003-2008页

作者： Yuan Ren Xuanyu Yang Xinran Zhou Wei Luo Yi Zhang Xiaowei Cheng Yonghui Deng Department of Chemistry State Key Laboratory of Molecular Engineering of PolymersShanghai Key Laboratory of Molecular Catalysis and Innovative MaterialsiChEMFudan UniversityShanghai 200433China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua UniversityShanghai 201620China School of Materials Science and Energy Engineering Foshan UniversityFoshan 528000China

Mesoporous late-transition metal oxides have great potential in applications of energy,catalysis and chemical sensing due to their unique physical and chemical ***,their synthesis via the flexible and scalable soft-template method remain a great challenge,due to the weak organic-inorganic interaction between the frequently used surfactants(e.g.,Pluronic-type block copolymers) and metal oxide precursors,and the low crystallization temperature of metal *** this study,ordered mesoporous NiO with dual mesopores,high surface area and well-interconnected crystalline porous frameworks have been successfully synthesized via the facile solvent evaporation-induced co-assembly(EICA) method,by using lab-made amphiphilic diblock copolymer polystyrene-b-poly(4-vinylpyridine)(PS-b-P4 VP) as both the structure-directing agent(the soft template) and macromolecular chelating agents for nickel species,THF as the solvent,and nickel acetylacetonate(Ni(acac)2) as inorganic ***,by using Ni(acac)2 and Fe(acac)3 as the binary precursors,ordered mesoporous Fedoped NiO materials can be obtained,which have bimodal mesopores of large mesopores(32.5 nm) and secondary mesopores(4.0-11.5 nm) in the nanocrystal-assembled walls,high specific surface areas(~74.8 m^2/g) and large pore value(~0.167 cm^3/g).The obtained mesoporous Fe-doped NiO based gas sensor showed superior ethanol sensing performances with good sensitivity,high selectivity and fast response-recovery dynamics.

关键词： Block copolymer Co-assembly Metal oxides Mesoporous Gas sensing

Rational design of thermoelastic damping in microresonators with phase-lagging heat conduction law

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2022年第11期43卷 1675-1690页

作者： Yu FU Li LI Hongfang CHEN Xuelin WANG Ling LING Yujin HU State Key Laboratory of Digital Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

The design of thermoelastic damping(TED)affected by the phase-lagging non-Fourier heat conduction effects becomes significant but challenging for enlarging the quality factor of widely-used microresonators operating in extreme situations,including ultra-high excitation frequency and ultra-low working ***,there does not exist a rational method for designing the TED in the framework of non-Fourier heat conduction *** work,therefore,proposes a design framework to achieve low thermoelastic dissipation of microresonators governed by the phase-lagging heat conduction *** equation of motion and the heat conduction equation for phase-lagging TED microresonators are derived first,and then the non-Fourier TED design problem is proposed.A topology optimization-based rational design method is used to resolve the design *** is more,a two-dimensional(2D)plain-strain-based finite element method(FEM)is developed as a solver for the topology optimization *** on the suggested rational design technique,numerical instances with various phase lags are *** results show that the proposed design method can remarkably reduce the dissipation of microresonators by tailoring their substructures.

关键词： microresonator non-Fourier damping factor topology optimization

Modeling of Cyclic Bending of Thin Foils Using Higher-Order Strain Gradient Plasticity

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2022年第4期35卷 616-631页

作者： Tong Luo Fenfei Hua Dabiao Liu School of Aerospace Engineering Huazhong University of Science and TechnologyWuhan430074China Hubei Key Laboratory of Engineering Structural Analysis and Safety Assessment Wuhan430074China

The plastic behaviors of thin metallic foils,including size effect,Bauschinger effect,and passivation effect,are studied under cyclic bending condition using the strain gradient visco-plasticity *** finite element simulations are performed on the cyclic bending of the elasto-viscoplastic thin foils with passivated and unpassivated *** study is also conducted on the transition from a passivated surface to an unpassivated *** roles of the dissipative and energetic gradient terms are *** the results,it is found that the dissipative gradient terms increase the yield strength,while the energetic gradient terms increase the strain hardening,resulting in an anomalous Bauschinger ***,it is observed that the surface passivation effect increases both the normalized bending moment at initial yielding and strain *** comparison between the numerical results of cases with and without passivation demonstrates that the switching of boundary conditions significantly affects the plastic behavior of the foils under cyclic bending.

关键词： Strain gradient plasticity Size effect Bauschinger effect Geometrically necessary dislocations Bending

CRISPR-Cas System for RNA Detection and Imaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2020年第2期36卷 157-163页

作者： CHEN Siyu WANG Rujia LEI Chunvang NIE Zhou State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan Provincial Key Laboratory of Bioniacromolecular Chemical BiologyHunan UniversityChangsha 410082P.R.China

The system of clustered regularly interspaced short palindromic repeats(CRISPR)and CRISPR-associated endonucleases(Cas)have been widely used in gene editing,disease treatment,molecular diagnosis and chromosome *** account of the programmable target recognition of CRISPR-Cas system and the specific targeting function toward RNA of type Ⅵ class Ⅱ Cas proteins,CRISPR-Cas system has been deployed as RNA recognition and detection tools,exhibiting promising application potentials in the field of RNA detection and *** this review,we summarize the latest research progresses as well as development prospects of CRISPR-Cas system in RNA diagnosis and live cell RNA imaging.

关键词： Clustered regularly interspaced short palindromic repeats-associated endonucleases(CRISPR-Cas) RNA detection RNA imaging Collateral cleavage

Emerging Nano-/Biotechnology Drives Oncolytic Virus-Activated and Combined Cancer Immunotherapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research 2023年第4期2023卷 515-538页

作者： Chao Fang Gaozhe Xiao Taixia Wang Li Song Bo Peng Bin Xu Kun Zhang Central Laboratory and Department of Urology Shanghai Tenth People’s HospitalTongji University School of MedicineTongji UniversityNo.301 Yan-chang-zhong RoadShanghai 200072China National Center for International Research of Bio-targeting Theranostics Guangxi Medical UniversityNo.22 Shuangyong Road 22NanningGuangxi 530021China Department of Urology Shanghai Ninth People’s HospitalShanghai Jiaotong University School of MedicineNo.639 Zhizaoju RoadHuangpuShanghai 200011China.

Oncolytic viruses(OVs)as one promising antitumor methods have made important contributions to tumor immunotherapy,which arouse increasing *** provide the dual mechanisms including direct killing effect toward tumor cells and immune activation for elevating antitumor responses,which have been proved in many preclinical ***,natural or genetically modified viruses as clinical immune preparations have emerged as a new promising approach objective to oncology *** approval of talimogene laherparepvec(T-VEC)by the *** and Drug Administration(FDA)for the therapy of advanced melanoma could be considered as a milestone achievement in the clinical translation of *** this review,we first discussed the antitumor mechanisms of OVs with an emphasis on targeting,replication,and *** further outlined the state of the art of current OVs in tumor and underlined the activated biological effects especially including *** significantly,the enhanced immune responses based on OVs were systematically discussed from different perspectives such as combination with immunotherapy,genetic engineering of OVs,integration with nanobiotechnology or nanoparticles,and antiviral response counteraction,where their principles were shed light *** development of OVs in the clinics was also highlighted to analyze the actuality and concerns of different OV applications in clinical *** last,the future perspectives and challenges of OVs as an already widely accepted treatment means were *** review will provide a systematic review and deep insight into OV development and also offer new opportunities and guidance pathways to drive the further clinical translation.

关键词： approval insight antitumor

Damping of aluminum-matrix composite reinforced by carbon nanotube:Multiscale modeling and characteristics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2023年第4期66卷 1062-1074页

作者： WANG Fei LI Li TANG HaiShan WANG XueLin HU YuJin State Key Laboratory of Digital Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

It is a crucial requirement for structure-damping materials to attain both stiffness and damping;unfortunately,the two properties are usually mutually *** study interestingly demonstrates that introducing Ni atoms into the interface of carbon nanotube(CNT)reinforced aluminum-matrix composites can defeat the conflict of stiffness versus *** originates from the gradient variation of the modulus and energy dissipation in the effective interfacial *** rule of mixture is modified by taking the interface contribution into account,and a gradient damping model is proposed to account for the contribution of the interface energy *** dynamics simulations confirm that the proposed multiscale modulus and damping models can describe the elastic modulus and damping behavior of the composites with different volume fractions and different diameters of *** gradient interface slip caused by the lattice mismatches and misfit dislocations between Ni-coated CNT and aluminum is one of the pathways for achieving unprecedented levels of the product of stiffness and damping.

关键词： molecular dynamics interfacial dissipation elastic modulus damping loss modulus

Formation of high-density cold molecules via electromagnetic trap

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2022年第10期31卷 371-376页

作者： Ya-Bing Ji Bin Wei Heng-Jiao Guo Qing Liu Tao Yang Shun-Yong Hou Jian-Ping Yin State Key Laboratory of Precision Spectroscopy East China Normal UniversityShanghai 200241China Key Laboratory of Nondestructive Test(Ministry of Education) Nanchang Hangkong UniversityNanchang 330063China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

Preparation and control of cold molecules are advancing rapidly, motivated by many exciting applications ranging from tests of fundamental physics to quantum information processing. Here, we propose a trapping scheme to create high-density cold molecular samples by using a combination of electric and magnetic fields. In our theoretical analysis and numerical calculations, a typical alkaline-earth monofluoride, MgF, is used to test the feasibility of our proposal.A cold MgF molecular beam is first produced via an electrostatic Stark decelerator and then loaded into the proposed electromagnetic trap, which is composed of an anti-Helmholtz coil, an octupole, and two disk electrodes. Following that,a huge magnetic force is applied to the molecular sample at an appropriate time, which enables further compressing of the spatial distribution of the cold sample. Molecular samples with both higher number density and smaller volume are quite suitable for the laser confinement and other molecular experiments such as cold collisions in the next step.

关键词： Stark effect Zeeman effect cold molecules