检索结果-南通市图书馆

Nontargeted identification of peptides and disinfection byproducts in water

Journal of environmental Sciences 2016年第4期28卷 259-266页

作者： Yanan Tang Ying Xu Feng Li Lindsay Jmaiff Steve E.Hrudey Xing-Fang Li Division of Analytical and environmental Toxicology Department of Laboratory Medicine and PathologyUniversity of Alberta Department of Computer Science University of Alberta

A broad range of organic compounds are known to exist in drinking water sources and serve as precursors of disinfection byproducts（DBPs）.Epidemiological findings of an association of increased risk of bladder cancer with the consumption of chlorinated water has resulted in health concerns about *** are thought to be an important category of DBP precursors in ***,little is known about the actual presence of peptides and their DBPs in drinking water because of their high sample complexity and low *** address this challenge and identify peptides and non-chlorinated/chlorinated peptide DBPs from large sets of organic compounds in water,we developed a novel high throughput analysis strategy,which integrated multiple solid phase extraction（SPE）,high performance liquid chromatography（HPLC）separation,and non-target identification using precursor ion exclusion（PIE）high resolution mass spectrometry（MS）.After MS analysis,structures of candidate compounds,particularly peptides,were obtained by searching against the Human Metabolome Database（HMDB）.Using this strategy,we successfully detected 625 peptides（out of 17,205 putative compounds）and 617 peptides（out of 13,297）respectively in source and finished water *** source and finished water samples had 501 peptides and amino acids in *** remaining 116 peptides and amino acids were unique to the finished *** a subset of 30 putative compounds for which standards were available,25 were confirmed using HPLC-MS *** analyzing the peptides identified in source and finished water,we successfully confirmed three disinfection reaction pathways that convert peptides into toxic DBPs.

关键词： Nontargeted detection Water analysis Mass spectrometry Peptide Disinfection byproducts

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Arsenobetaine:the ongoing mystery

引用

National Science Review 2016年第4期3卷 451-458页

作者： Aleksandra Popowich Qi Zhang X.Chris Le Department of Chemistry University of Alberta Division of Analytical and environmental Toxicology Department of Laboratory Medicine and PathologyUniversity of Alberta

Arsenobetaine(As B) is a non-toxic organoarsenical identiied as a major arsenic species in marine animals and a number of terrestrial *** its irst identiication nearly 40 years ago,numerous studies investigating the biosynthesis and function of As B have been carried out,although molecular mechanisms have not been fully *** and how is As B formed? Why do marine animals acquire high concentrations of As B? his review briely summarizes the current progress of As B research toward understanding its origin,function and the putative pathways for its *** paper also suggests potential future studies in the atempt to solve the As B mystery.

关键词： arsenic arsenobetaine arsenocholine arsenosugars biosynthesis arsenic metabolism speciation

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Shale gas reservoirs: Theoretical, practical and research issues

引用

Petroleum Research 2016年第1期1卷 10-26页

作者： Roberto Aguilera Schulich School of Engineering University of CalgaryCalgaryCanada

Shale gas reservoirs are found all over the *** endowment worldwide is estimated at 10,000 tcf by the GFREE team in the Schulich School of Engineering at the University of *** shale gas work and production initiated successfully in the Unites States and extended to Canada will have application,with modifications,in several other countries in the ***‘modifications’qualifier is important as each shale gas reservoir should be considered as a research project by itself to avoid fiascos and major financial *** gas reservoirs are best represented by at least quadruple porosity *** of the production obtained from shale reservoirs is dominated by diffusion *** approximate boundary between viscous and diffusion-like flow is estimated with Knudsen *** flow is present,for example,when the architecture of the rock is dominated by mega pore throat,macro pore throat,meso pore throat and sometimes micro pore *** flow on the other hand is observed at the nano pore throat *** process speed concept has been used successfully in conventional reservoirs for several ***,the concept discussed in this paper for tight gas and shale gas reservoirs,with the support of core data,has been developed only recently,and permits differentiating between viscous and diffusion dominated *** is valuable,for example,in those cases where the formation to be developed is composed of alternating stacked layers of tight sands and shales,or where there are lateral variations due to facies *** approach to develop the concept of a super-giant shale gas reservoir is presented as well as a description of GFREE,a successful research program for tight *** paper closes with examples of detailed original gas-in-place(OGIP)calculations for 3 North American shale gas reservoirs including free gas in natural fractures and the porous network within the organic matter,gas in the non-organic matter,adsorbed gas,a

关键词： shale gas reservoirs process or delivery speed quadruple porosity model Knudsen number pore throat level

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：