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Journal of Zhejiang University-science A(Applied Physics & Engineering) 2024年第1期25卷 79-96页

作者： Haoyu SUN Haiyang MA Li WANG Yang LIU Tian HOU Wenjie TANG Qing YU Meiwen AN Meiling WEN Institute of Biomedical Engineering College of Biomedical EngineeringTaiyuan University of TechnologyTaiyuan030024China

Three-dimensional(3D)hydrogel models play a crucial role in tissue engineering for promoting tissue regeneration.A biomimetic microchannel network system in the 3D hydrogel model is necessary for optimal cellular *** report describes the preparation of a biomimetic hydrogel scaffold with an internal microchannel network,using electrospinning techniques and the sacrificial template method for 3D cell *** and cavities were created within the gelatin methacryloyl(GelMA)hydrogel by sacrificing polyvinyl alcohol(PVA)electrospun fibers(>10µm),resulting in the creation of microvessel-like *** characterizations,swelling properties,and biodegradation analysis were conducted to investigate the feasibility of a biomimetic microchannel network hydrogel scaffold for 3D cell culture *** to pure GelMA hydrogel,the hydrogel with microchannels promoted cell proliferation,adhesion,and endothelial tube ***,the results confirmed that the biomimetic microchannel network scaffold had a major impact on the distribution and arrangement of human umbilical vein endothelial cells(HUVECs)and can enable the formation of artificial microvasculature by the culture of HUVECs and cell media perfusion.

关键词： Biomimetic scaffold Photocrosslinking Microchannel network Tissue engineering Artificial microvascular

Modification of streamer-to-leader transition model based on radial thermal expansion in the sphere-plane gap discharge at high altitude

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Plasma science and Technology 2024年第1期26卷 42-49页

作者：耿江海林果王平丁玉剑丁杨俞华 Department of Electric Power Engineering North China Electric Power UniversityBaoding 071003People’s Republic of China china Electric Power Research Institute Beijing 100192People’s Republic of China Xinjiang Electric Power Company Research Institute Urumchi 830000People’s Republic of China Shanxi Electric Power Company Research Institute Taiyuan 030001People’s Republic of China

Historically,streamer-to-leader transition studies mainly focused on the rod-plane gap and low altitude analysis,with limited attention paid to the sphere-plane gap at high altitude *** this work,sphere-plane gap discharge tests were carried out under the gap distance of 5 m at the Qinghai Ultra High Voltage(UHV)test base at an altitude of 2200 *** experiments measured the physical parameters such as the discharge current,electric field intensity and instantaneous optical *** duration of the dark period and the critical charge of streamer-toleader transition were obtained at high *** on radial thermal expansion of the streamer stem,we established a modified streamer-to-leader transition model of the sphere-plane gap discharge at high altitude,and calculated the stem temperature,stem radii and the duration of streamer-to-leader *** with the measured duration of sphere-plane electrode discharge at an altitude of 2200 m,the error rate of the modified model was 0.94%,while the classical model was 6.97%,demonstrating the effectiveness of the modified *** the comparisons and analysis,several suggestions are proposed to improve the numerical model for further quantitative investigations of the leader inception.

关键词： streamer-to-leader transition model high altitude streamer stem convective diffusion radial thermal expansion

Amphipathic Phenylalanine-Induced Nucleophilic-Hydrophobic Interface Toward Highly Reversible Zn Anode

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Nano-Micro Letters 2024年第9期16卷 95-109页

作者： Anbin Zhou Huirong Wang Fengling Zhang Xin Hu Zhihang Song Yi Chen Yongxin Huang Yanhua Cui Yixiu Cui Li Li Feng Wu Renjie Chen Beijing Key Laboratory of Environmental science and Engineering School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081People’s Republic of China Advanced Technology Research Institute Beijing Institute of TechnologyJinan 250300People’s Republic of China Collaborative Innovation Center of Electric Vehicles in Beijing Beijing 100081People’s Republic of China Institute of Electronic Engineering China Academy of Engineering PhysicsMianyang 621900People’s Republic of China

Aqueous Zn^(2+)-ion batteries(AZIBs),recognized for their high security,reliability,and cost efficiency,have garnered considerable ***,the prevalent issues of dendrite growth and parasitic reactions at the Zn electrode interface significantly impede their practical *** this study,we introduced a ubiquitous biomolecule of phenylalanine(Phe)into the electrolyte as a multifunctional additive to improve the reversibility of the Zn *** its exceptional nucleophilic characteristics,Phe molecules tend to coordinate with Zn^(2+)ions for optimizing the solvation ***,the distinctive lipophilicity of aromatic amino acids empowers Phe with a higher adsorption energy,enabling the construction of a multifunctional protective *** hydrophobic benzene ring ligands act as cleaners for repelling H_(2)O molecules,while the hydrophilic hydroxyl and carboxyl groups attract Zn^(2+)ions for homogenizing Zn^(2+)***,the preferential reduction of Phe molecules prior to H_(2)O facilitates the in situ formation of an organic-inorganic hybrid solid electrolyte interphase,enhancing the interfacial stability of the Zn ***,Zn||Zn cells display improved reversibility,achieving an extended cycle life of 5250 ***,Zn||LMO full cells exhibit enhanced cyclability of retaining 77.3%capacity after 300 cycles,demonstrating substantial potential in advancing the commercialization of AZIBs.

关键词： Zn anode Phenylalanine Adsorption energy Solvation sheath

Chiral liquid crystals based on pillararene and supramolecular self-assembly-induced chirality amplification

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science china Chemistry 2024年第10期67卷 3373-3381页

作者： Bicong Liang Yujie Cheng Xiong Liu Lan Jia Xuehong Wei Qiang Zheng Pi Wang Danyu Xia Xuzhou Yan College of Materials science and Engineering Taiyuan University of TechnologyTaiyuan 030024China Scientific Instrument Center Shanxi UniversityTaiyuan 030006China School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghai 200240China

Macrocyclic liquid crystals combine the unique property of liquid crystals and excellent supramolecular assembly ability of macrocyclic *** is a significant challenge to make rational use of the advantages of macrocyclic compounds to prepare new macrocyclic ***,a type of macrocycles with rigid pillar-shaped frameworks and easy-tofunctionalize property,are excellent building blocks to fabricate liquid crystal ***,the site-selective modification property of pillararene has been rarely exploited to tailor liquid crystal *** reported pillararene-based liquid crystal systems are almost prepared by per-functionalized ***,we report the regulation of chiral liquid crystal behaviors by different derivatization of *** and thermotropic liquid crystals with different chirality were obtained by self-assembly of pillararene with different numbers of cholesterol *** bridge between thermotropic liquid crystal and lyotropic liquid crystal based on pillararene is *** addition,the chirality of the mesogens can be amplified through supramolecular self-assembly driven by noncovalent *** on the different liquid crystal behaviors,the optical signal of the pillararene-based chiral liquid crystals was used to fabricate an information encryption *** work provides a simple strategy to regulate liquid crystal behaviors via pillararene-based mesogens and realizes information encryption through the combination of different types of liquid crystals.

关键词： chiral liquid crystal pillararene self-assembly cholesterol information encryption

SDCC: software-defined collective communication for distributed training

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science china(Information sciences) 2024年第9期67卷 105-125页

作者： Xin JIN Zhen ZHANG Yunshan JIA Yun MA Xuanzhe LIU School of Computer science Peking University Department of Computer science and Technology Johns Hopkins University

Communication is crucial to the performance of distributed training. Today's solutions tightly couple the control and data planes and lack flexibility, generality, and performance. In this study, we present SDCC, a software-defined collective communication framework for distributed training. SDCC is based on the principle of modern systems design to effectively decouple the control plane from the data *** abstracts the operations for collective communication in distributed training with dataflow operations and unifies computing and communication with a single dataflow graph. The abstraction, together with the unification, is powerful: it enables users to easily express new and existing collective communication algorithms and optimizations, simplifies the integration with different computing engines(e.g., Py Torch and Tensor Flow) and network transports(e.g., Linux TCP and kernel bypass), and allows the system to improve performance by exploiting parallelism exposed by the dataflow graph. We further demonstrate the benefits of SDCC in four use cases.

关键词： machine learning systems distributed training deep learning collective communication software-defined networking

The acceptance of traditional Chinese medicine among patients with Parkinson's disease:A hospital survey

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Journal of Integrative Medicine 2024年第2期22卷 180-187页

作者： Peng Wang Jing Hong Zhu-qian Tang Bi-zhen Gong Xiao-rong Qi Han Jiang Bo Pan Qi Chen Postgraduate School Medical School of Chinese People’s Liberation ArmyBeijing 100853China Senior Department of Traditional Chinese Medicine the Sixth Medical Center of PLA General HospitalBeijing 100853China Department of Integration of Chinese and Western Medicine School of Basic Medical SciencesPeking UniversityBeijing 100191China Department of Integrative Oncology the First Affiliated Hospital of Naval Medical UniversityShanghai 200433China School of Traditional Chinese Medicine Naval Medical UniversityShanghai 200433China School of Pharmacy Nanjing University of Chinese MedicineNanjing 210023Jiangsu ProvinceChina Department of Dermatology the First Clinical Medical CollegeAnhui University of Chinese MedicineHefei 230012Anhui ProvinceChina

Objective:The efficacy of medications for Parkinson’s disease(PD)tend to decline over time,which has a serious impact on patients’health and quality of *** some extent,traditional Chinese medicine(TCM)can resolve the distressing problem of ineffective dopaminergic medication in PD *** purpose of this study was to investigate the attitude,acceptance,and independent predictors of TCM in PD patients admitted to the outpatient department of a tertiary ***:A cross-sectional study of PD patients was conducted in the outpatient department of a large tertiary hospital in Beijing from March 2022 to June 2023.A self-report questionnaire was developed to investigate PD patients’attitudes and acceptance of TCM based on the *** logistic regression analyses were also performed to further clarify the independent predictors influencing patients’adoption of TCM ***:A total of 397 patients completed the questionnaire,of which 78.09%were willing to be treated with TCM and 21.91%indicated that they were not willing to use *** logistic regression analysis showed that several parameters were correlated with a patient’s willingness to include TCM in their therapeutic *** included education level of a bachelor’s degree(odds ratio[OR)=8.554;95%confidence interval[CI]:4.112–17.794;P<0.001,vs junior high school education),living in an urban setting(OR=8.022;95%CI:4.577–14.060;P<0.001,vs rural),having other underlying diseases(OR=5.126;95%CI:3.078–8.537;P<0.001,vs none),having previously used TCM(OR=3.083;95%CI:1.852–5.134;P<0.001,vs not used),believing that TCM therapy is safe(OR=3.530;95%CI:1.446–8.616;P=0.006,vs not thought),believing that TCM therapy is effective(OR=3.859;95%CI:1.482–10.047;P=0.006,vs not understood),and being willing to discuss ongoing TCM therapy with an attending physician(OR=62.468;95%CI:30.350–128.574;P<0.001,vs not informed).Conclusion:This study initially investigated the acceptance

关键词： Parkinson's disease Traditional Chinese medicine Cross-sectional study

Gate-field control of valley polarization in valleytronics

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Chinese Physics B 2024年第6期33卷 2-12页

作者：张婷婷韩依琳张闰午余智明 Institute of Physics Chinese Academy of SciencesBeijing 100190China Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement Beijing Key Laboratory of Nanophotonics&Ultrafine Optoelectronic Systemsand School of PhysicsBeijing Institute of TechnologyBeijing 100081China

Valleytronics materials are a kind of special semiconductors which can host multiple symmetry-connected and wellseparated electron or hole pockets in the Brillouin zone when the system is slightly n or p doped. Since the low-energy particles residing in these pockets generally are not easily scattered to each other by small perturbations, they are endowed with an additional valley degree of freedom. Analogous to spin, the valley freedom can be used to process information,leading to the concept of valleytronics. The prerequisite for valleytronics is the generation of valley polarization. Thus,a focus in this field is achieving the electric generation of valley polarization, especially the static generation by the gate electric field alone. In this work, we briefly review the latest progress in this research direction, focusing on the concepts of the couplings between valley and layer, i.e., the valley–layer coupling which permits the gate-field control of the valley polarization, the couplings between valley, layer, and spin in magnetic systems, the physical properties, the novel designing schemes for electronic devices, and the material realizations of the gate-controlled valleytronics materials.

关键词： band structure electronic transport optical properties spintronics

Separation density prediction of geldart A^(-)dense medium in gas-solid fluidized bed coal beneficiators

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Particuology 2024年第9期92卷 251-262页

作者： Chenyang Zhou Chengguo Liu Yue Yuan Zhijie Fu Jesse Zhu Chenlong Duan School of Chemical Engineering and Technology China University of Mining and TechnologyXuzhou221116China Particle Technology Research Centre Western UniversityLondonOntarioN6A 5B9Canada

Gas-solid Fluidized Bed Coal Beneficiator(GFBCB)process is a crucial dry coal beneficiation fluidization *** work employs the GFBCB process alongside a novel Geldart A^(-)dense medium,consisting of Geldart A magnetite particles and Geldart C ultrafine coal,to separate small-size separated objects in the *** effects of various operational conditions,including the volume fraction of ultrafine coal,the gas velocity,the separated objects size,and the separation time,were investigated on the GFBCB's separation *** results indicated that the probable error for 6∼3 mm separated objects could be controlled within 0.10 g/cm^(3).Compared to the traditional Geldart B/D dense medium,the Geldart A/A^(-)dense medium exhibited better size-dependent separation performance with an overall probable error 0.04∼0.12 g/cm^(3).Moreover,it achieved a similar separation accuracy to the Geldart B/D dense medium fluidized bed with different external energy for the small-size object *** work furthermore validated a separation density prediction model based on theoretical derivation,available for both Geldart B/D dense medium and Geldart A/A^(-)dense medium at different operational conditions.

关键词： GFBCB Geldart A^(-)dense medium Separation density Separated objects size Prediction model

SIRT1 inhibits apoptosis of human lens epithelial cells through suppressing endoplasmic reticulum stress in vitro and in vivo

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1205-1216页

作者： Hui Cui Di Sun Sheng Meng Tian-Ju Ma Zi Ye Zhao-Hui Li Medical School of Chinese PLA Beijing 100089China Senior Department of Ophthalmology the Third Medical Center of PLA General HospitalBeijing 100853China

AIM:To explore the effect of silent information regulator factor 2-related enzyme 1(SIRT1)on modulating apoptosis of human lens epithelial cells(HLECs)and alleviating lens opacification of rats through suppressing endoplasmic reticulum(ER)***:HLECs(SRA01/04)were treated with varying concentrations of tunicamycin(TM)for 24h,and the expression of SIRT1 and C/EBP homologous protein(CHOP)was assessed using real-time quantitative polymerase chain reaction(RT-PCR),Western blotting,and *** morphology and proliferation was evaluated using an inverted microscope and cell counting kit-8(CCK-8)assay,*** the SRA01/04 cell apoptosis model,which underwent siRNA transfection for SIRT1 knockdown and SRT1720 treatment for its activation,the expression levels of SIRT1,CHOP,glucose regulated protein 78(GRP78),and activating transcription factor 4(ATF4)were *** potential reversal of SIRT1 knockdown effects by 4-phenyl butyric acid(4-PBA;an ER stress inhibitor)was *** vivo,age-related cataract(ARC)rat models were induced by sodium selenite injection,and the protective role of SIRT1,activated by SRT1720 intraperitoneal injections,was evaluated through morphology observation,hematoxylin and eosin(H&E)staining,Western blotting,and ***:SIRT1 expression was downregulated in TMinduced SRA01/04 ***,in SRA01/04 cells,both cell apoptosis and CHOP expression increased with the rising doses of *** stress was stimulated by TM,as evidenced by the increased GRP78 and ATF4 in the SRA01/04 cell apoptosis *** of SIRT1 by siRNA knockdown increased ER stress activation,whereas SRT1720 treatment had opposite results.4-PBA partly reverse the adverse effect of SIRT1 knockdown on *** vivo,SRT1720 attenuated the lens opacification and weakened the ER stress activation in ARC rat ***:SIRT1 plays a protective role against TM-induced apoptosis in HLECs and slows the progression of cataract in

关键词： silent information regulator factor 2-related enzyme 1 endoplasmic reticulum stress apoptosis human lens epithelial cells cataract

Numerical Study on the Effect of Gap Diffraction on the Hydrodynamic Performance of A Floating Breakwater

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china Ocean Engineering 2024年第4期38卷 663-675页

作者： BIAN Xiang-qian JI Chun-yan XU Sheng GUO Jian-ting HUO Fa-li School of Naval Architecture and Ocean Engineering Jiangsu University of Science and TechnologyZhenjiang 212100China

Two-dimensional(2D)flume experiments are useful in investigating the performances of floating breakwaters(FBs),including hydrodynamic performances,motion responses,and mooring *** a reasonable gap between the flume wall and the FBs is a critical step in 2D flume ***,research on the effect of the gap on the accuracy of 2D FB experimental results is *** address this issue,a numerical wave tank is developed using CFD to estimate the wave-FB interaction of a moored dual-cylindrical FB,and the results are compared to experimental data from a previously published *** is good agreement between them,indicating that the numerical model is sufficiently *** numerical model is then applied to explore the effect of gap diffraction on the performance of FBs in2D *** was discovered that the nondimensional gap length L_(Gap)/W_(Pool)should be smaller than 7.5%to ensure that the relative error of the transmission coefficient is smaller than 3%.The influence of the gap is also related to the entering wave properties,such as the wave height and period.

关键词： floating breakwater diffraction effect gap hydrodynamic performance model experiments CFD numerical simulation