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Propensity score matching analysis for clinical impact of braided-type versus laser-cut-type covered self-expandable metal stents for endoscopic ultrasound-guided hepaticogastrostomy

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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 181-185页

作者： Mitsuki Tomita Takeshi Ogura Akitoshi Hakoda Saori Ueno Atsushi Okuda Nobu Nishioka Yoshitaro Yamamoto Hiroki Nishikawa 2nd Department of Internal Medicine Osaka Medical and Pharmaceutical UniversityOsakaJapan Endoscopy Center Osaka Medical and Pharmaceutical UniversityOsakaJapan

Background:To prevent stent migration during endoscopic ultrasound-guided hepaticogastrostomy(EUS-HGS),intra-scope channel release technique is important,but is unfamiliar to non-expert *** self-expandable metal stent(SEMS)is an additional factor to prevent stent ***,no compara-tive studies of laser-cut-type and braided-type during EUS-HGS have been *** aim of this study was to compare the distance between the intrahepatic bile duct and stomach wall after EUS-HGS among laser-cut-type and braided-type ***:To evaluate stent anchoring function,we measured the distance between the hepatic parenchyma and stomach wall before EUS-HGS,one day after EUS-HGS,and 7 days after ***,propensity score matching was performed to create a propensity score for using laser-cut-type group and braided-type ***:A total of 142 patients were enrolled in this *** them,24 patients underwent EUS-HGS using a laser-cut-type SEMS,and 118 patients underwent EUS-HGS using a braided-type ***-HGS using the laser-cut-type SEMS was mainly performed by non-expert endoscopists(n=21);EUS-HGS using braided-type SEMS was mainly performed by expert endoscopists(n=98).The distance after 1 day was significantly shorter in the laser-cut-type group than that in the braided-type group[2.00(1.70-3.75)vs.6.90(3.72-11.70)mm,P<0.001].In addition,this distance remained significantly shorter in the laser-cut-type group after 7 *** these results were similar after propensity score matching analysis,the distance between hepatic parenchyma and stomach after 7 days was increased by 4 mm compared with the distance after 1 day in the braided-type *** the other hand,in the laser-cut-type group,the distance after 1 day and 7 days was almost the ***:EUS-HGS using a laser-cut-type SEMS may be safe to prevent stent migration,even in non-expert hands.

关键词： Endoscopic ultrasound-guided hepaticogastrostomy Endoscopic ultrasound-guided biliary drainage Endoscopic retrograde cholangiopancreatography

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Poly(ethylenimine)-assisted synthesis of hollow carbon spheres comprising multi-sized Ni species for CO_(2)electroreduction

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Chinese Journal of Catalysis 2024年第9期64卷 66-76页

作者： Kaining Li Yasutaka Kuwahara Hiromi Yamashita Division of Materials and Manufacturing Science Graduate School of EngineeringOsaka University2‐1 Yamada‐okaOsaka 565‐0871Japan Innovative Catalysis Science Division Institute for Open and Transdisciplinary Research Initiatives(OTRI)Osaka University2‐1 Yamada‐okaSuitaOsaka 565‐0871Japan

Electrochemical CO_(2)reduction to produce value-added chemicals and fuels is one of the research hotspots in the field of energy *** development of efficient catalysts with high conductivity and readily accessible active sites for CO_(2)electroreduction remains challenging yet *** this work,a reliable poly(ethyleneimine)(PEI)-assisted strategy is developed to prepare a hollow carbon nanocomposite comprising a single-site Ni-modified carbon shell and confined Ni nanoparticles(NPs)(denoted as Ni@NHCS),where PEI not only functions as a mediator to induce the highly dispersed growth of Ni NPs within hollow carbon spheres,but also as a nitrogen precursor to construct highly active atomically-dispersed Ni-Nx *** from the unique structural properties of Ni@NHCS,the aggregation and exposure of Ni NPs can be effectively prevented,while the accessibility of abundant catalytically active Ni-Nx sites can be *** a result,Ni@NHCS exhibits a high CO partial current density of 26.9 mA cm^(-2)and a Faradaic efficiency of 93.0%at-1.0 V ***,outperforming those of its PEI-free *** from the excellent activity and selectivity,the shell confinement effect of the hollow carbon sphere endows this catalyst with long-term *** findings here are anticipated to help understand the structure-activity relationship in Ni-based carbon catalyst systems for electrocatalytic CO_(2)***,the PEI-assisted synthetic concept is potentially applicable to the preparation of high-performance metal-based nanoconfined materials tailored for diverse energy conversion applications and beyond.

关键词： Hollow carbon sphere Ni nanoparticle CO_(2)reduction Electrocatalysis Single-atom catalyst

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Mechanocatalysis of CO to CO_(2)on TiO_(2)surface controlled at atomic scale

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Nano Research 2024年第7期17卷 5826-5834页

作者： Yuuki Adachi Robert Turanský Ján Brndiar Kamil Tokár Qiang Zhu Huan Fei Wen Yasuhiro Sugawara IvanŠtich Yan Jun Li Department of Applied Physics Osaka University2-1 YamadaokaSuitaOsaka 565-0871Japan Institute of Physics Slovak Academy of SciencesBratislava 84511Slovakia Institute of Informatics Slovak Academy of SciencesBratislava 84507Slovakia Faculty of Natural Sciences University of Ss.Cyril and MethodiusTrnava 91701Slovakia Key Laboratory of Instrumentation Science and Dynamic Measurement School of Instrument and ElectronicsNorth University of ChinaTaiyuan 030051China

The common ways to activate a chemical reaction are by heat,electric current,or ***,mechanochemistry,where the chemical reaction is activated by applied mechanical force,is less common and only poorly understood at the atomic *** we report a tip-induced activation of chemical reaction of carbon monoxide to dioxide on oxidized rutile TiO_(2)(110)*** activation is studied by atomic force microscopy,Kelvin probe force microscopy under ultrahigh-vacuum and liquid nitrogen temperature conditions,and density functional theory(DFT)*** reaction is inferred from hysteretic behavior of frequency shift signal further supported by vector force mapping of vertical and lateral forces needed to trigger the chemical reaction with torque motion of carbon monoxide towards an oxygen *** reaction is found to proceed stochastically at very small tip-sample ***,the local contact potential difference reveals the atomic-scale charge redistribution in the reactants required to unlock the *** results open up new insights into the mechanochemistry on metal oxide surfaces at the atomic scale.

关键词： atomic resolution mechanochemistry atomic force microscopy Kelvin probe force microscopy density functional theory(DFT)simulation CO oxidation catalysis rutile TiO_(2)surface

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A Hydrogen-Bonded,Hexagonally Networked,Layered Framework with Large Aperture Designed by Structural Synchronization of a Macrocycle and Supramolecular Synthon

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Precision Chemistry 2024年第5期2卷 221-228页

作者： Hiroki Yoshimura Ryusei Oketani Miki Naruoka Norimitsu Tohnai Ichiro Hisaki Division of Chemistry Graduate School of Engineering ScienceOsaka UniversityToyonakaOsaka 560-8531Japan Department of Applied Chemistry Graduate School of EngineeringOsaka UniversitySuitaOsaka 565-0871Japan

To develop porous organic frameworks,precise control of the stacking manner of two-dimensional porous motifs and structural characterization of the resultant framework are *** these points of view,porous molecular crystals formed through reversible intermolecular hydrogen bonds,such as;hydrogen-bonded organic frameworks(HOFs),can provide deep insight because of their high crystallinity,affording single-crystalline X-ray diffraction *** this study,we demonstrate that the stacking manner of hydrogen-bonded hexagonal network(HexNet)sheets can be controlled by synchronizing a homological triangular macrocyclic tecton and a hydrogen-bonded cyclic supramolecular synthon called the phenylene triangle.A structure of the resultant HOF was crystallographically characterized and revealed to have a large channel aperture of 2.4 *** HOF also shows thermal stability up to 290°C,which is higher than that of the conventional HexNet frameworks.

关键词： hydrogen-bonded organicframeworks hexagonalnetwork macrocycle carboxylicacid porosity

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Psychological potential field and human eye fixation on binary line-drawing images: A comparative experimental study

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Computational Visual Media 2020年第2期6卷 205-214页

作者： Naoyuki Awano Yuki Hayashi osaka university of Economics OsakaOsaka533-8533Japan osaka Prefecture university SakaiOsaka599-8531Japan

Quantitatively evaluating the psychological and perceptual effects of objects is an important issue,but is difficult. In cognitive studies, the psychological potential field(PPF), which represents psychological intensities in vision and can be calculated by applying computational algorithms to digital images, may help with this issue. Although studies have reported using the PPF to evaluate psychological effects, such as impressions, detailed investigations on how the PPF represents psychological perception and its limitations have not yet been performed. Another relevant tool is the fixation map, which visualizes human eye fixations;this map is generated from actual measurements acquired by eye-tracking and does not represent psychological effects directly. Although the PPF and the fixation map are based on visual imaging, they have never been compared. In this paper, we do so for the first time, using psychological and perceptual properties of line-drawing images. The results demonstrate the difference between these methods, including their representation of different properties with respect to visual perception. Moreover, the similarity between the two methods highlights the possibility of assessing perceptual phenomena such as categorization and cognition of objects based on human vision.

关键词： psychological potential field(PPF) eye fixation eye-tracking visual perception line drawing

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Autonomic and cardiovascular effects of pentobarbital anesthesia during trigeminal stimulation in cats

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International Journal of Oral Science 2012年第1期4卷 24-29页

作者： Hiroshi Hanamoto Hitoshi Niwa Mitsutaka Sugimura Yoshinari Morimoto Department of Dental Anesthesiology Osaka University Graduate School of DentistryOsakaJapan

Stimulation of the trigeminal nerve can elicit various cardiovascular and autonomic responses;however,the effects of anesthesia with pentobarbital sodium on these responses are *** sodium was infused intravenously at a nominal rate and the lingual nerve was electrically stimulated at each infusion *** in systolic blood pressure（SBP） and heart rate（HR） were evoked by lingual nerve stimulation at an infusion rate between 5 and 7 mg？kg 21 ？h *** response was associated with an increase in the low-frequency band of SBP variability（SBP-LF）.As the infusion rate increased to 10 mg？kg 21 ？h 21 or more,decreases in SBP and HR were *** response was associated with the reduction of *** conclusion,lingual nerve stimulation has both sympathomimetic and sympathoinhibitory effects,depending on the depth of pentobarbital *** reaction pattern seems to be closely related to the autonomic balance produced by pentobarbital anesthesia.

关键词： autonomic nervous system blood pressure and heart rate variability hemodynamics trigeminal depressor response

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A Wide Learning Approach for Interpretable Feature Recommendation for 1-D Sensor Data in IoT Analytics

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International Journal of Automation and computing 2019年第6期16卷 800-811页

作者： Snehasis Banerjee Tanushyam Chattopadhyay Utpal Garain TCS Research&Innovation Tata Consultancy ServicesEcospaceKolkata 700160India Computer Vision&Pattern Recognition Unit Indian Statistical Institute203 B.T.RoadKolkata 700108India

This paper presents a state of the art machine learning-based approach for automation of a varied class of Internet of things(Io T) analytics problems targeted on 1-dimensional(1-D) sensor data. As feature recommendation is a major bottleneck for general Io Tbased applications, this paper shows how this step can be successfully automated based on a Wide Learning architecture without sacrificing the decision-making accuracy, and thereby reducing the development time and the cost of hiring expensive resources for specific problems. Interpretation of meaningful features is another contribution of this research. Several data sets from different real-world applications are considered to realize the proof-of-concept. Results show that the interpretable feature recommendation techniques are quite effective for the problems at hand in terms of performance and drastic reduction in development time.

关键词： Feature engineering sensor data analysis Internet of things(IoT)analytics interpretable learning automation

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Electrodeposition and growth mechanism of preferentially orientated nanotwinned Cu on silicon wafer substrate

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Journal of Materials Science & Technology 2018年第10期34卷 1885-1890页

作者： Fu-Long Sun Li-Yin Gao Zhi-Quan Liu Hao Zhang Tohru Sugahara Shijo Nagao Katsuaki Suganuma Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 China university of Chinese Academy of Sciences Beijing 100049 China Institute of Scientific and Industrial Research Osaka University Osaka 5670047 Japan

Homogeneous columnar Cu film with fully embedded nanotwins was successfully fabricated on Ti/Cu seed layer on silicon wafer. The nanotwins with thickness of tens of nanometers are generally parallel to the silicon surface, showing a strong （111 ） preferred orientation. The acid concentration was found to be important in influencing the formation of nanoscale twins. By adjusting the acid concentration, the nanotwins can be induced from the top columnar grain to middle columnar grain and reach the bottom equiaxed grain, and a microstructural transformation model was given. A theory focusing on the cathode overpotential was proposed to reveal the effect of acid concentration on the growth mechanism of nanoscale twins. An appropriate adsorption proportion of hydrogen on cathode （acid concentration 17 ml L^-1） could increase the overpotential which supplies adequate nucleation energy for nanoscale twins formation.

关键词： Electrodeposition Nanotwinned Cu Growth mechanism Acid adsorption

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Liver cirrhosis in a child associated with Castleman's disease: A case report

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World Journal of Clinical Cases 2020年第9期8卷 1656-1665页

作者： Soya Kobayashi Ayano Inui Tomoyuki Tsunoda Syuichiro Umetsu Tsuyoshi Sogo Masaaki Mori Masato Shinkai Tomoo Fujisawa Department of Pediatric Hepatology and Gastroenterology Saiseikai Yokohama City Tobu HospitalYokohama 230-8765Japan Department of Lifetime Clinical Immunology Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyo 113-8519Japan Department of Surgery Kanagawa Children’s Medical CenterYokohama 232-8555Japan

BACKGROUND Castleman's disease(CD)is a lymphoproliferative *** syndrome is classified as a variant of CD based on its key clinical manifestations of thrombocytopenia,anasarca(generalized edema and pleural effusion),fever(pyrexia),reticulin fibrosis in the bone marrow and the proliferation of megakaryocytes,and organomegaly(such as hepatosplenomegaly and multiple lymphadenopathies);TAFRO syndrome is mainly reported in Japanese *** our knowledge,this is the first pediatric case report detailing a CD-associated disorder progressing to *** SUMMARY A 10-year old male patient presented with fever and *** months before hospitalization,he had remarkable abdominal ***,he visited a clinic for a fever that lasted 5 *** physical findings were marked hepatosplenomegaly and cervical lymphadenopathy.A blood test revealed leukocytosis,microcytic anemia,aspartate aminotransferase-dominant transaminase elevation,high levels of C-reactive protein,polyclonal hypergammaglobulinemia,and high levels of interleukin-6 and vascular endothelial growth *** contrast computed tomography and magnetic resonance imaging suggested cirrhosis,which was confirmed by liver *** findings in the enlarged hepatic lymph nodes revealed both hyperplasia and atrophy of lymphoid follicles with some vascular hyperplasia and moderate plasmacytosis between the lymphoid follicles,which is compatible with lymph node histology in TAFRO *** was not effective in reducing the patient’s symptoms;therefore,the patient was prescribed *** date,the patient remains free of fever and continues to receive *** We described the clinicopathological features of TAFRO syndrome to highlight the clinical presentation of this rare disease in a pediatric case.

关键词： Castleman disease Case report Multi-centric Castleman’s disease Liver cirrhosis Tocilizumab Child

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The emerging role of Arid5a in cancer: A new target for tumors

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Genes & Diseases 2023年第3期10卷 813-824页

作者： Kishan Kumar Nyati Tadamitsu Kishimoto Laboratory of Immune Regulation World Premier International Immunology Frontier Research CenterOsaka UniversityOsaka 5650871Japan

AT-rich interactive domain 5a (Arid5a) is a member of the arid family of proteins, which contain a helix-turn-helix domain and an ability to bind to nucleic acids. Current evidence suggests that Arid5a performs dual functions as a transcription factor and an RNA-binding protein in immune, nonimmune, and/ or tumor cells depending on its cellular localization. The contribution of Arid5a to the development of inflammation, autoimmunity, and obesity through its transcriptional and posttranscriptional regulatory functions has broadly been reviewed. Recent studies have indeed revealed an association of Arid5a with cancers, including breast, pancreatic, colorectal, and lung cancers and glioma. Notably, Arid5a affects various aspects of cellular homeostasis, including invasion, metastasis, epithelial-to-mesenchymal transition, immune evasion, adipogenesis and M1-like tumor-associated macrophage (TAM)-to-M2-like TAM transition. This review aims to summarize current knowledge of Arid5a from a cancer perspective and highlights recent advances in Arid5a-related cancer research. This review may improve the understanding of Arid5a-mediated molecular mechanisms and their relevance to cancers.

关键词： Arid5a Cancer Inflammation Metastasis Transcriptional and posttanscriptional regulation Tumor micr oenvir onment

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