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Functional connectivity and information flow in cerebral motor regions of healthy people following finger movement training

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Neural Regeneration Research 2010年第9期5卷 710-714页

作者： Zeqiang Yang Dongmei Hao Ying Li Yanping Bai College of Life Science and Bioengineering Beijing University of Technology Beijing 100124 China

BACKGROUND：Neuro-rehabilitative training has been shown to promote motor function recovery in stroke patients,although the underlying mechanisms have no. been fully ***：To investigate the effects of finger movement training on functional connectivity and information flow direction in cerebral motor areas of healthy people using electroencephalogram （EEG）.DESIGN,TIME AND SETTING：A self-controlled,observational study was performed at the College of Life Science and Bioengineering,Beijing University of Techno.ogy between December 2008 and April ***：Nineteen healthy adults,who seldom played musical instruments or keyboards,were included in the present ***：Specific finger movement training was performed,and all subjects were asked to separately press keys with their left or right hand fingers,according to *** task comprised five sessions of test train test ***-six channel EEG signals were recorded in different test sessions prior to and after *** were statistically analyzed using one-way analysis of *** OUTCOME MEASURES：The number of effective performances,correct ratio,average response time,average movement time,correlation coefficient between pairs of EEG channels,and information flow direction in motor regions were analyzed and compared between different training ***：Motor function of all subjects was significantly improved in the third test comparedwith the first test （P〈 0.01）.More than 80% of connections were strengthened in the motor-related areas following two training sessions,in particular the primary motor regions under the C4 *** to the first test,a greater amount of information flowed from the Cz and Fcz electrodes （corresponding to supplementary motor area） to the C4 electrode in the third ***：Finger task training increased motor ability in subjects by strengthening connections and changing information flow in the motor ***

关键词： motor cortex functional connectivity information flow direction electroencephalogram

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916 MHz electromagnetic field exposure affects rat behavior and hippocampal neuronal discharge

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Neural Regeneration Research 2012年第19期7卷 1488-1492页

作者： Dongmei Hao Lei Yang Su Chen Yonghao Tian Shuicai Wu College of Life Science and Bioengineering Beijing University of Technology Beijing 100124 China College of Biomedical Engineering South-Central University for Nationalities Wuhan 430074 Hubei Province China

Wistar rats were exposed to a 916 MHz, 10 W/m2 mobile phone electromagnetic field for 6 hours a day 5 days a week. Average completion times in an eight-arm radial maze were longer in the exposed rats than control rats after 4-5 weeks of exposure. Error rates in the exposed rats were greater than the control rats at 6 weeks. Hippocampal neurons from the exposed rats showed irregular firing patterns during the experiment, and they exhibited decreased spiking activity 6-9 weeks compared with that after 2 5 weeks of exposure. These results indicate that 916 MHz electromagnetic fields influence leaming and memory in rats during exposure, but long-term effects are no. obvious.

关键词： electromagnetic field Wistar rats maze learning feeding behavior neurons neural regeneration

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