Functional connectivity and information flow in cerebral motor regions of healthy people following finger movement training

作     者：Zeqiang Yang Dongmei Hao Ying Li Yanping Bai 

作者机构：College of Life Science and Bioengineering Beijing University of Technology Beijing 100124 China 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2010年第5卷第9期

页      面：710-714页

核心收录：

学科分类：10[医学] 

基　　金：the National Natural Science Foundation of China No. 30670543 

主　　题：motor cortex functional connectivity information flow direction electroencephalogram 

摘      要：BACKGROUND：Neuro-rehabilitative training has been shown to promote motor function recovery in stroke patients,although the underlying mechanisms have not been fully ***：To investigate the effects of finger movement training on functional connectivity and information flow direction in cerebral motor areas of healthy people using electroencephalogram （EEG）.DESIGN,TIME AND SETTING：A self-controlled,observational study was performed at the College of Life Science and Bioengineering,Beijing University of Technology between December 2008 and April ***：Nineteen healthy adults,who seldom played musical instruments or keyboards,were included in the present ***：Specific finger movement training was performed,and all subjects were asked to separately press keys with their left or right hand fingers,according to *** task comprised five sessions of test train test ***-six channel EEG signals were recorded in different test sessions prior to and after *** were statistically analyzed using one-way analysis of *** OUTCOME MEASURES：The number of effective performances,correct ratio,average response time,average movement time,correlation coefficient between pairs of EEG channels,and information flow direction in motor regions were analyzed and compared between different training ***：Motor function of all subjects was significantly improved in the third test comparedwith the first test （P〈 0.01）.More than 80% of connections were strengthened in the motor-related areas following two training sessions,in particular the primary motor regions under the C4 *** to the first test,a greater amount of information flowed from the Cz and Fcz electrodes （corresponding to supplementary motor area） to the C4 electrode in the third ***：Finger task training increased motor ability in subjects by strengthening connections and changing information flow in the motor ***