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Waste fly ash-ZnO as a novel sunlight-responsive photocatalyst for dye discoloration

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Water Science and Engineering 2023年第1期16卷 76-82页

作者： Leena V.Bora Sonal P.Thakkar Kevin S.Vadaliya Nisha V.Bora nirma university AhmedabadGujarat 382481India Government Engineering College ModasaGujarat 383315India

Treating waste with a waste material using freely available solar energy is the most effective way towards sustainable *** this study,a novel photocatalyst,partly derived from waste material from the coal industry,was *** ash hybridized with ZnO(FAeZn)was synthesized as a potential photocatalyst for dye *** synthesized photocatalyst was characterized by X-ray diffraction,scanning electron microscopy,transmission electron microscopy,and ultravioletevisible/near infra-red *** photocatalytic activity was examined with the discoloration of methylene blue used as synthetic dye *** the experiments were performed in direct *** photocatalytic performance of FAeZn was found to be better than that of ZnO and the conventionally popular *** LangmuireHinshelwood model rate constant values of ZnO,TiO2,and FAeZn were found to be 0.016 min1,0.017 min1,and 0.020 min1,*** were two reasons for this:(1)FAeZn was able to utilize both ultraviolet and visible parts of the solar spectrum,and(2)its BrunauereEmmetteTeller surface area and porosity were significantly *** led to increased photon absorption and dye adsorption,thus exhibiting an energy-efficient ***,FAeZn,partly derived from waste,can serve as a suitable material for environmental remediation and practical solar energy applications.

关键词： Photocatalyst ZnO Fly ash Geopolymer Wastewater treatment Methylene blue

C-phycocyanin shows neuroprotective effect against rotenone-induced Parkinson’s disease in mice

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Asian Pacific Journal of Tropical Biomedicine 2024年第7期14卷 279-287页

作者： Hritik Rathod Ritu M.Soni Jigna S.Shah Department of Pharmacology Institute of Pharmacy Nirma UniversityAhmedabadGujaratIndia

Objective:To investigate the neuroprotective effect of C-phycocyanin in a mouse model of rotenone-induced Parkinson’s ***:C-phycocyanin(50 mg/kg,i.p.,daily)was administered to rotenone(30 mg/kg,p.o.,daily)treated mice for 28 *** studies(Y-maze,rotarod,round beam walk,and wire-hang tests)were carried out to assess neurobehavioral *** and malondialdehyde were determined in both serum and striatal *** proteins(AKT,AMPK,NF-κB,BDNF,and alpha-synuclein)in the striatum were estimated using *** analyses(hematoxylin and eosin stainning as well as Nissl staining)were carried out to assess structural abnormalities in the ***:C-phycocyanin significantly increased BDNF levels and decreased alpha-synuclein *** also slightly upregulated AMPK and AKT levels without significant difference compared with the rotenone ***,rotenone-induced elevated oxidative stress and structural abnormalities in the striatum were markedly mitigated by ***:C-phycocyanin might have potential neuroprotective effects against Parkinson’s *** studies are warranted to verify its efficacy and to understand the molecular mechanisms behind the neuroprotective effects of C-phycocyanin in Parkinson’s disease.

关键词： Parkinson’s disease C-phycocyanin Alphasynuclein BDNF Oxidative stress Rotenone

Insights on drug and gene delivery systems in liver fibrosis

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Asian Journal of Pharmaceutical Sciences 2023年第2期18卷 4-27页

作者： Kunj Vyas Mayur M Patel Department of Pharmaceutics Institute of PharmacyNirma University SG HighwayGujarat 382481India

Complications of the liver are amongst the world’s worst *** fibrosis is the first stage of liver problems,while cirrhosis is the last stage,which can lead to *** creation of effective anti-fibrotic drug delivery methods appears critical due to the liver’s metabolic capacity for drugs and the presence of insurmountable physiological impediments in the way of *** breakthroughs in anti-fibrotic agents have substantially assisted in fibrosis;nevertheless,the working mechanism of anti-fibrotic medications is not fully understood,and there is a need to design delivery systems that are well-understood and can aid in ***-based delivery systems are regarded to be effective but they have not been adequately researched for liver *** a result,the capability of nanoparticles in hepatic delivery was *** approach is targeted drug delivery,which can considerably improve efficacy if delivery systems are designed to target hepatic stellate cells(HSCs).We have addressed numerous delivery strategies that target HSCs,which can eventually aid in *** genetics have proved to be useful,and methods for delivering genetic material to the target place have also been investigated where different techniques are *** summarize,this review paper sheds light on themost recent breakthroughs in drug and gene-based nano and targeted delivery systems that have lately shown useful for the treatment of liver fibrosis and cirrhosis.

关键词： Liver fibrosis Gene delivery system Nano drug delivery system Cirrhosis Targeted delivery system Vector

Enhancement in antinociceptive and anti-inflammatory effects of tramadol by transdermal proniosome gel

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Asian Journal of Pharmaceutical Sciences 2020年第6期15卷 786-796页

作者： Jigar Shah Anroop B.Nair Hiral Shah Shery Jacob Tamer M.Shehata Mohamed Aly Morsy Institute of Pharmacy Nirma UniversityAhmedabad 382481India College of Clinical Pharmacy King Faisal UniversityAl-Ahsa 31982Saudi Arabia Arihant School of Pharmacy&BRI Gandhinagar 382421India College of Pharmacy Gulf Medical UniversityAjman 4184United Arab Emirates Faculty of Pharmacy University of ZagazigZagazig 44519Egypt Faculty of Medicine Minia UniversityEl-Minia 61511Egypt

Oral therapy of tramadol,an opiate analgesic,undergoes extensive hepatic metabolism and requires frequent *** therapy by virtue can overcome these issues and can improve the efficacy and reduce abuse liability of *** aim of this research was to investigate the possibility of transdermal delivery of tramadol by formulating proniosome gel and evaluate its therapeutic potential in *** effect of formulation composition as well as amount of drug on physicochemical characteristics of prepared proniosomes were *** proniosome gel(F4)was selected and evaluated for drug release,stability and transdermal efficacy by ex vivo and in vivo *** vesicles demonstrated optimal properties including spherical shape,nanosize with good entrapment efficiency,adequate zeta potential,higher stability and greater transdermal *** amorphization and dispersion of tramadol in the aqueous core of proniosome vesicles was confirmed by differential scanning *** profile of F4 was distinct(P<0.001)from control and displayed steady and prolonged tramadol release by Fickian *** therapy of F4 showed prominent reduction of induced twitches(P<0.005)in mice and edema(P<0.05)in rats,as compared to oral *** improvement in clinical efficacy of tramadol in transdermal therapy is correlated with the pharmacokinetic data *** conclusion,the observed improvement in antinociceptive and anti-inflammatory effects from proniosome carriers signifies its potential to be a suitable alternative to oral therapy of tramadol with greater efficacy.

关键词： Tramadol Proniosomes Flux Edema Pharmacokinetics Rats

Systematic review and meta-analysis of augmented reality in medicine, retail, and games

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Visual Computing for Industry,Biomedicine,and Art 2020年第1期3卷 227-246页

作者： Pranav Parekh Shireen Patel Nivedita Patel Manan Shah Department of Computer Engineering Nirma UniversityAhmedabadGujarat 382481India Department of Chemical Engineering School of TechnologyPandit Deendayal Petroleum UniversityGandhinagarGujaratIndia

This paper presents a detailed review of the applications of augmented reality(AR)in three important fields where AR use is currently *** objective of this study is to highlight how AR improves and enhances the user experience in entertainment,medicine,and *** authors briefly introduce the topic of AR and discuss its differences from virtual *** also explain the software and hardware technologies required for implementing an AR system and the different types of displays required for enhancing the user *** growth of AR in markets is also briefly *** the three sections of the paper,the applications of AR are *** use of AR in multiplayer gaming,computer games,broadcasting,and multimedia videos,as an aspect of entertainment and gaming is *** in medicine involves the use of AR in medical healing,medical training,medical teaching,surgery,and post-medical *** in retail was discussed in terms of its uses in advertisement,marketing,fashion retail,and online *** authors concluded the paper by detailing the future use of AR and its advantages and disadvantages in the current scenario.

关键词： Augmented reality Software Medicine Gaming

A comprehensive review of machine learning techniques on diabetes detection

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Visual Computing for Industry,Biomedicine,and Art 2021年第1期4卷 308-323页

作者： Toshita Sharma Manan Shah Department of Electronics and Communication Technology Nirma University382481 AhmedabadGujaratIndia Department of Chemical Engineering School of TechnologyPandit Deendayal Energy University382426 GandhinagarGujaratIndia

Diabetes mellitus has been an increasing concern owing to its high morbidity,and the average age of individual affected by of individual affected by this disease has now decreased to *** the high prevalence,it is necessary to address with this problem *** researchers and doctors have now developed detection techniques based on artificial intelligence to better approach problems that are missed due to human *** mining techniques with algorithms such as-density-based spatial clustering of applications with noise and ordering points to identify the cluster structure,the use of machine vision systems to learn data on facial images,gain better features for model training,and diagnosis via presentation of iridocyclitis for detection of the disease through iris patterns have been deployed by various *** learning classifiers such as support vector machines,logistic regression,and decision trees,have been comparative discussed various *** learning models such as artificial neural networks and recurrent neural networks have been considered,with primary focus on long short-term memory and convolutional neural network architectures in comparison with other machine learning *** parameters such as the root-mean-square error,mean absolute errors,area under curves,and graphs with varying criteria are commonly *** this study,challenges pertaining to data inadequacy and model deployment are *** future scope of such methods has also been discussed,and new methods are expected to enhance the performance of existing models,allowing them to attain greater insight into the conditions on which the prevalence of the disease depends.

关键词： Machine learning Deep learning Health care Diabetes detection

Artificial cognition for applications in smart agriculture: A comprehensive review

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Artificial Intelligence in Agriculture 2020年第1期4卷 81-95页

作者： Misbah Pathan Nivedita Patel Hiteshri Yagnik Manan Shah Department of Computer Engineering Silver Oak College of Engineering and TechnologyAhmedabadGujaratIndia Department of Computer Engineering Nirma University AhmedabadGujaratIndia Guj Info Petro Limited(GIPL) GandhinagarGujaratIndia Department of Chemical Engineering School of TechnologyPandit Deendayal Petroleum UniversityGandhinagarGujaratIndia

Agriculture contributes to 6.4%of the entire world's economic *** at least nine countries of the world,agriculture is the dominant sector of the *** not only provides the fuel for billions of people but also employment opportunities to a large number of *** agricultural industries are seeking innovative approaches for improving crop yielding because of unpredictable climatic changes,the rapid increase in population growth and food security ***,artificial intelligence in agriculture also called“Agriculture Intelligence”is progressively emerging as a part of the industry's technological *** aim of this paper is to review various applications of agriculture intelligence such as precision farming,disease detection,and crop phenotyping with the help of numerous tools such as machine learning,deep learning,image processing,artificial neural network,deep learning,convolution neural network,Wireless Sensor Network(WSN)technology,wireless communication,robotics,Internet of Things(IoT),different genetic algorithms,fuzzy logic and computer vision to name a *** the help of these technologies,the use of the colossal volume of chemicals can be used reduced,which would result in reduced expenditure improved soil fertility along with elevated productivity.

关键词： Artificial intelligence Diseased Agriculture Precision farming Phenotyping

Comprehensive review of text‑mining applications in finance

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Financial Innovation 2020年第1期6卷 732-756页

作者： Aaryan Gupta Vinya Dengre Hamza Abubakar Kheruwala Manan Shah Department of Computer Science Nirma UniversityAhmedabadGujaratIndia Department of Chemical Engineering School of TechnologyPandit Deendayal Petroleum UniversityGandhinagarGujarat 382007India

Text-mining technologies have substantially affected financial *** the data in every sector of finance have grown immensely,text mining has emerged as an important field of research in the domain of ***,reviewing the recent literature on text-mining applications in finance can be useful for identifying areas for further *** paper focuses on the text-mining literature related to financial forecasting,banking,and corporate *** also analyses the existing literature on text mining in financial applications and provides a summary of some recent ***,the paper briefly discusses various text-mining methods being applied in the financial domain,the challenges faced in these applications,and the future scope of text mining in finance.

关键词： Text mining Machine learning Financial forecasting Sentiment analysis Text classification Corporate finance

Bio-Nanocarriers for Lung Cancer Management:Befriending the Barriers

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Nano-Micro Letters 2021年第9期13卷 238-291页

作者： Shruti Rawal Mayur Patel Department of Pharmaceutics Institute of PharmacyNirma UniversitySG HighwayChharodiAhmedabadGujarat 382481India

ABSTRACT Lung cancer is a complex thoracic malignancy developing consequential to aberrations in a myriad of molecular and biomolecular signaling *** is one of the most lethal forms of cancers accounting to almost 1.8 million new annual incidences,bearing overall mortality to incidence ratio of *** dismal prognostic scenario at advanced stages of the disease and metastatic/resistant tumor cell populations stresses the requisite of advanced translational interdisciplinary interventions such as *** review article deliberates insights and apprehensions on the recent prologue of nanobioengineering and bionanotechnology as an approach for the clinical management of lung *** role of nanobioengineered(bio-nano)tools like bio-nanocarriers and nanobiodevices in secondary prophylaxis,diagnosis,therapeutics,and theranostics for lung cancer management has been ***,bioinspired,and biomimetic bio-nanotools of considerate translational value have been *** on existent oncostrategies,their critical comparison with bio-nanocarriers,and issues hampering their clinical bench side to bed transformation have also been summarized.

关键词： Biomimetic nanoparticles Exosomes Circulating tumor cells Mesenchymal stem cells Theranostics