检索结果-南通市图书馆

Electrochemical protein biosensors for disease marker detection:progress and opportunities

Microsystems & Nanoengineering 2024年第3期10卷 1-20页

作者： Lanpeng Guo Yunong Zhao Qing Huang Jing Huang Yanbing Tao Jianjun Chen Hua-Yao Li Huan Liu School of Integrated Circuits Wuhan National Laboratory for OptoelectronicsOptics Valley LaboratoryHuazhong University of Science and TechnologyWuhan 430074China Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education School of Integrated CircuitsAnhui UniversityHefei 230601China School of Optoelectronic Materials and Technology Jianghan UniversityWuhan 430056China Department of Otorhinolaryngology Union HospitalTongji Medical CollegeHuazhong University of Science and Technology1277 Jiefang AvenueWuhan 430022China Wenzhou Institute of Advanced Manufacturing Technology Huazhong University of Science and TechnologyWenzhou 325000China

The development of artificial intelligence-enabled medical health care has created both opportunities and challenges for next-generation biosensor *** are extensively used as biological macromolecular markers in disease diagnosis and the analysis of therapeutic *** protein biosensors have achieved desirable specificity by using the specific antibody–antigen binding principle in ***,the active centers of protein biomarkers are surrounded by a peptide matrix,which hinders charge transfer and results in insufficient sensor ***,electrode-modified materials and transducer devices have been designed to increase the sensitivity and improve the practical application prospects of electrochemical protein *** this review,we summarize recent reports of electrochemical biosensors for protein biomarker *** highlight the latest research on electrochemical protein biosensors for the detection of cancer,viral infectious diseases,inflammation,and other *** corresponding sensitive materials,transducer structures,and detection principles associated with such biosensors are also addressed ***,we present an outlook on the use of electrochemical protein biosensors for disease marker detection for the next few years.

关键词： diagnosis specificity Electrochemical

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of Mn Addition and Heat Treatment on the Corrosion Behaviour of Mg-Ag-Mn Alloy

引用

Acta Metallurgica Sinica(English Letters) 2024年第4期37卷 665-677页

作者： You Lv Yupeng Zhang Xi Liu Zehua Dong Xiaorong Zhou Xinxin Zhang Key Laboratory of Material Chemistry for Energy Conversion and Storage Ministry of EducationHubei Key Laboratory of Material Chemistry and Service FailureSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan430074China hubei Engineering Research Centre for Biomaterials and Medical Protective Materials Huazhong University of Science and TechnologyWuhan430074China Corrosion and Protection Centre Department of MaterialsThe University of ManchesterManchesterM139PLUK

The high corrosion sensitivity and the potential bio-toxicity of Mg-Ag alloys limit their wide applications for the production of implanted devices. In the present work, Mn is added into the Mg-Ag alloy to optimize its corrosion behaviour. The corrosion behaviour of Mg-Ag-Mn alloys is investigated with the underlying microstructural factors examined. The Mg-Ag alloy with 2 wt% Mn exhibits the highest corrosion resistance after post-casting heat treatment at 440 ℃. The addition of Mn results in α-Mn phase with the incorporation of Fe, which suppresses the cathodic activity of impurity Fe. Further, heat treatment of the cast alloys homogenizes the distribution of Ag and promotes the precipitation of α-Mn phase. The former removes Ag segregations as potential cathodes;the latter promotes a more uniform distribution of cathodes and, therefore, prevents localized corrosion.

关键词： Mg-Ag alloy Mn addition Post-casting heat treatment Cathodic activity Corrosion mechanism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hybrid Dynamic Variables-Dependent Event-Triggered Fuzzy Model Predictive Control

引用

IEEE/CAA Journal of Automatica Sinica 2024年第3期11卷 723-733页

作者： Xiongbo Wan Chaoling Zhang Fan Wei Chuan-Ke Zhang Min Wu IEEE the School of Automation China University of Geosciencesthe Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex Systemsand the Engineering Research Center of Intelligent Technology for Geo-ExplorationMinistry of EducationWuhan 430074China

This article focuses on dynamic event-triggered mechanism(DETM)-based model predictive control(MPC) for T-S fuzzy systems.A hybrid dynamic variables-dependent DETM is carefully devised,which includes a multiplicative dynamic variable and an additive dynamic *** addressed DETM-based fuzzy MPC issue is described as a “min-max” optimization problem(OP).To facilitate the co-design of the MPC controller and the weighting matrix of the DETM,an auxiliary OP is proposed based on a new Lyapunov function and a new robust positive invariant(RPI) set that contain the membership functions and the hybrid dynamic variables.A dynamic event-triggered fuzzy MPC algorithm is developed accordingly,whose recursive feasibility is analysed by employing the RPI *** the designed controller,the involved fuzzy system is ensured to be asymptotically *** examples show that the new DETM and DETM-based MPC algorithm have the advantages of reducing resource consumption while yielding the anticipated performance.

关键词： Dynamic event-triggered mechanism(DETM) hybrid dynamic variables model predictive control(MPC) robust positive invariant(RPI)set T-S fuzzy systems

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A potential threat from biodegradable microplastics: mechanism of cadmium adsorption and desorption in the simulated gastrointestinal environment

引用

Frontiers of Environmental science & Engineering 2024年第2期18卷 63-75页

作者： Timing Jiang Xiang Wu Shushan Yuan Changfei Lai Shijie Bian Wenbo Yu Sha Liang Jingping Hu Liang Huang Huabo Duan Yafei Shi Jiakuan Yang School of Environmental science&Engineering Huazhong University of Science and TechnologyWuhan 430074China School of Resources and Environmental science Hubei UniversityWuhan 430062China hubei provincial Engineering Laboratory for Solid Waste Treatment Disposal and Recycling Wuhan 430074China School of Civil Engineering Architecture and EnvironmentHubei University of TechnologyWuhan 430068China State Key Laboratory of Coal Combustion Huazhong University of Science and TechnologyWuhan 430074China

It has been demonstrated that microplastics (MPs) can accumulate heavy metals from the environment and transfer them into organisms via the food chain. However, adsorption and desorption capacities for biodegradable MPs relative to those for conventional MPs remain poorly understood. In this study, cadmium (Cd(II)) adsorption and desorption characteristics of polylactic acid (PLA), a typical biodegradable MP, were investigated. Two conventional MPs, i.e., polypropylene (PP) and polyamide (PA) were used for comparison. The maximum Cd(II) adsorption capacities of the MPs studied in the adsorption experiments decreased in the order PA (0.96 ± 0.07 mg/g) > PLA (0.64 ± 0.04 mg/g) > PP (0.22 ± 0.03 mg/g). The Pseudo-second-order kinetic model and Freundlich isothermal model described the Cd(II) adsorption behaviors of PLA MPs well. X-ray photoelectron spectroscopy and two-dimensional Fourier transform infrared correlation spectroscopy analysis indicated that oxygen functional groups were the major and preferential binding sites of PLA MPs, which contributed to their high Cd(II) adsorption capacities. Simulated gastric and intestinal fluids both significantly enhanced the desorption capacities of the examined MPs. Notably, degradation of the PLA MPs during in vitro human digestion made the Cd(II) on the PLA MPs more bioaccessible (19% in the gastric phase and 62% in the intestinal phase) than Cd(II) on the PP and PA MPs. These results indicate the remarkable capacities of biodegradable MPs to accumulate Cd(II) and transfer it to the digestive system and show that biodegradable MPs might pose more severe threats to human health than conventional nonbiodegradable MPs.

关键词： Biodegradable microplastics Cadmium Adsorption and desorption Gastrointestinal environment Two-dimensional correlation spectroscopy Bioaccessibility

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Green Synthesis of Iron(Ⅱ,Ⅲ)-polyphenol Nanoparticles and Their Adsorption of Malachite Green

引用

Journal of Wuhan University of Technology(Materials science) 2024年第4期39卷 1025-1030页

作者：胡玉 ZHOU Fan ZHANG Nan PAN Xiaobin LI Shiying ZHANG Dong LI Li 张玲帆 Department of Chemistry and Environmental Engineering Hanjiang Normal UniversityShiyan 442000China Shiyan Hydrological and Water Resources Survey Bureau of hubei Province Shiyan 442000China School of Chemistry and Molecular Engineering East China University of Science and TechnologyShanghai 200237China

Three kinds of iron nanoparticles(FeNPs)were prepared via green route based on pomegranate(PG),green tea(GT),and mulberry(ML)extracts under ambient *** obtained materials were characterized by scanning electron microscopy(SEM),transmission electronic microscopy(TEM),X-ray energy-dispersive spectrometer(EDS),X-ray diffraction(XRD),fourier transform infrared spectroscopy(FTIR),and X-ray photoelectron spectroscopy(XPS)*** experimental results show that FeNPs were in the form of amorphous iron(Ⅱ,Ⅲ)-polyphenol complex with different dispersity and ***-Fe has the smallest size range of 25-35 nm,PG-Fe has a moderate size-distribution of 30-40 nm,while ML-Fe formed a tuberous net-type with a sheeting ***-Fe displays the highest removal efficiency of 90.2%in 20 min towards cationic dye of malachite green(16.6%by ML-Fe and 69.3%by GT-Fe),which is attributed to its highest polyphenol content,lowest zeta potential,as well as the most Fe^(2+)on the surface of *** removal mechanism was mainly induced by electrostatic adsorption based on pH and zeta potential tests.

关键词： iron nanoparticles pomegranate green tea mulberry adsorption

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A high-performance electrocatalyst for oxygen reduction derived from copolymer-anchored polyoxometalates

引用

Nano Research 2024年第6期17卷 5197-5205页

作者： Yue Du Wenxue Chen Zhiyi Zhong Zhixian Shi Yulin Zhang Xuanning Chen Yisi Liu Dongbin Xiong Lina Zhou Zhenhui Liu Mingbo Zheng hubei Key Laboratory of Photoelectric Materials and Devices&College of Material science and Engineering Hubei Normal UniversityHuangshi 435002China College of Materials science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016China

The development and synthesis of cathode electrocatalysts with high activity and durable stability for metal-air batteries is an important challenge in the area of ***,we introduce a novel in-situ nitriding and phosphating strategy for producing W_(3)N_(4)and WP from phosphotungstic acid(HPW)-polyaniline-phytic acid-Fe3+organic-inorganic hybrid *** final material has a three-dimensional porous framework with W_(3)N_(4)-WP heterostructures embedded in the carbon matrix(W_(3)N_(4)-WP@NPC).As-made materials exhibit exceptional electrocatalytic performance for the oxygen reduction reaction(ORR),with a diffusion-limiting current density of 6.9 mA·cm^(−2)and a half-wave potential of 0.82 *** a Zn-air primary cathode,the W_(3)N_(4)-WP@NPC assembled battery can provide a relatively high peak power density(194.2 mW·cm^(−2)).As a Zn-air secondary air-cathode,it has great cycling stability over 500 *** work provides a simple and efficient method for rationally designing high-performance air cathodes from copolymer-anchored polyoxometalates.

关键词： W_(3)N_(4)-WP heterojunctions copolymer-anchored polyoxometalates oxygen reduction reaction Zn-air battery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Semantic segmentation via pixel-to-center similarity calculation

引用

CAAI Transactions on Intelligence Technology 2024年第1期9卷 87-100页

作者： Dongyue Wu Zilin Guo Aoyan Li Changqian Yu Nong Sang Changxin Gao National Key Laboratory of science and Technology on Multispectral Information Processing School of Artificial Intelligence and AutomationHuazhong University of Science and TechnologyWuhanChina Meituan Inc. BeijingChina

Since the fully convolutional network has achieved great success in semantic segmentation,lots of works have been proposed to extract discriminative pixel ***,the authors observe that existing methods still suffer from two typical challenges:(i)The intra-class feature variation between different scenes may be large,leading to the difficulty in maintaining the consistency between same-class pixels from different scenes;(ii)The inter-class feature distinction in the same scene could be small,resulting in the limited performance to distinguish different classes in each *** authors first rethink se-mantic segmentation from a perspective of similarity between pixels and class *** weight vector of the segmentation head represents its corresponding semantic class in the whole dataset,which can be regarded as the embedding of the class ***,the pixel-wise classification amounts to computing similarity in the final feature space between pixels and the class *** this novel view,the authors propose a Class Center Similarity(CCS)layer to address the above-mentioned challenges by generating adaptive class centers conditioned on each scenes and supervising the similarities between class *** CCS layer utilises the Adaptive Class Center Module to generate class centers conditioned on each scene,which adapt the large intra-class variation between different *** designed Class Distance Loss(CD Loss)is introduced to control both inter-class and intra-class distances based on the predicted center-to-center and pixel-to-center ***,the CCS layer outputs the processed pixel-to-center similarity as the segmentation *** experiments demonstrate that our model performs favourably against the state-of-the-art methods.

关键词： computer vision deep neural networks image segmentation scene understanding

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Roles of Cu doping in YbZn_(2)Sb_(2) for thermoelectric performance enhancement

引用

Rare Metals 2024年第6期43卷 2869-2875页

作者： Xiong Zhang Hai-Hui Li Xiao-Liang Cao Bin Zhang Hong Wu Yu Zhang Guang Han Guo-Yu Wang Hao-Shuang Gu Xiao-Yuan Zhou College of Physics and Electronic science Hubei Normal UniversityHuangshi 435002China Analytical and Testing Center Chongqing UniversityChongqing401331China School of science Chongqing University of Posts and Telecommunications.Chongqing 400065 China College of Materials science and Engineering Chongqing UniversityChongqing 400044China hubei Collaborative Innovation Center for Advanced Organic Chemical Materials-hubei Key Laboratory of Ferro&Piezoelectric Materials and Devices Faculty of Physical and Electronic SciencesHubei UniversityWuhan 430062China College of Physics Chongqing UniversityChongqing 401331China

Recent research shows that increasing the carrier density after orbital alignment in AZn_(2)Sb_(2) (A=Ca,Yb,Eu,Sr,Mg)Zintl compounds yields remarkable results with regard to enhanced thermoelectric ***,research on carrier density increase via doping in these compounds is *** this study,we introduced Cu into the Zn sites in YbZn_(2)Sb_(2) and examined the thermoelectric properties.

关键词： properties doping performance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Targeting both ferroptosis and pyroptosis may represent potential therapies for acute liver failure

引用

World Journal of Gastroenterology 2024年第33期30卷 3791-3798页

作者： Zhong-Yuan Xing Chuan-Jie Zhang Li-Juan Liu Department of Medical Microbiology School of Basic Medical SciencesWuhan UniversityWuhan 430071Hubei ProvinceChina Department of Children Health Care Wuhan Children’s Hospital(Wuhan Maternal and Child Healthcare Hospital)Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430061Hubei ProvinceChina

In this editorial,we comment on the article published in the recent issue of the World Journal of *** liver failure(ALF)is a fatal disease that causes uncontrolled massive hepatocyte death and rapid loss of liver *** and pyroptosis,cell death forms that can be initiated or blocked concurrently,can play significant roles in developing inflammation and various ***,their roles in ALF remain *** article discovered the positive feedback between ferroptosis and pyroptosis in the progression of ALF,and revealed that the silent information regulator sirtuin 1(SIRT1)inhibits both pathways through p53,dramatically reducing inflammation and protecting *** suggests the potential use of SIRT1 and its downstream molecules as therapeutics for ***,we will discuss the role of ferroptosis and pyroptosis in ALF and the crosstalk between these cell death ***,we address potential treatments that could alleviate ALF by simultaneously inhibiting both cell death pathways,as well as examples of SIRT1 activators being used as disease treatment strategies,providing new insights into the therapy of ALF.

关键词： Acute liver failure Ferroptosis Pyroptosis Crosstalk Silent information regulator sirtuin 1 P53 Glutathione peroxidase 4 Gasdermin D Treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Etching Mechanism of Ti_(3)C_(2)Cl_(2) MXene Phases by CuCl_(2)-Lewis Molten Salt Method

引用

Journal of Wuhan University of Technology(Materials science) 2024年第4期39卷 863-868页

作者：严明 ZHU Yu HUANG Jiangtao CHEN Haoyu DENG Yuxiao CHEN Yanlin 王娟 Jan-Michael Albina hubei provincial Key Laboratory of Green Materials for Light Industry Hubei University of TechnologyWuhan 430068China New Materials and Green Manufacturing Talent Introduction and Innovation Demonstration Base Hubei University of TechnologyWuhan 430068China hubei Longzhong Laboratory Xiangyang 441000China

We described a method for obtaining fluorine-free Ti_(3)C_(2)Cl_(2)MXene phases by melting copper in CuCl_(2)instead of aluminum in Ti_(3)AlC_(2).XRD results show that when molten salt CuCl_(2)etches Ti_(3)AlC_(2),it forms an intermediate product Ti_(3)CuC_(2),and then reacts with Ti_(3)CuC_(2)to obtain Ti_(3)C_(2)Cl_(2).The reaction of Ti_(3)AlC_(2)and CuCl_(2)at a temperature of 800℃for 2 h to obtain Ti_(3)C_(2)Cl_(2)with an optimal lamellar structure is shown in SEM *** pseudopotential plane-wave(PP-PW)method is used to calculate on the electronic *** etching mechanism is investigated by the total energies of each *** chemical reaction of Ti_(3)AlC_(2)and CuCl_(2)will first become Ti_(3)CuC_(2)and Cu,and then become Ti_(3)C_(2)Cl_(2)during the Lewis acid etching process,which are consistent with the experimental results.

关键词： molten salt method CuCl_(2) MXene first-principles calculations etching mechanism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：