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Exploration of the therapeutic effect and clinical outcomes of acupuncture at pain-sensitive points to treat chronic nonspecific low back pain:Application of the acupoint sensitization theory

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World Journal of Acupuncture-Moxibustion 2021年第4期31卷 270-274页

作者： Yu-chong YE Ou-feng TANG Ya-zhen WU Xia-ying CAI Ben-hai CHEN Yi-chun LI Dong LIN Li-li LIN School of Acupuncture-moxibustion Fujian University of Traditional Chinese MedicineFuzhouFujian Province 350122China Mindong Hospital of Ningde City FuanFujian Province 355000China School of Nursing Fujian University of Traditional Chinese MedicineFuzhouFujian Province 350122China

Objectives:To investigate the clinical and therapeutic effects of acupuncture at the pain-sensitive points of patients with chronic nonspecific low back pain and optimize the acupuncture treatment for chronic nonspecific low back ***:Using the FDK 20 pressure algometer,the pain-sensitive points were probed in 30 patients with chronic nonspecific low back *** top 5 points that elicited the most painful reaction were selected and stimulated with an even-needling technique after *** needles were retained for 30 *** irradiation was concurrently *** treatment was administered once daily on weekdays(Monday to Friday) and discontinued for 2 days during the weekend(Saturday and Sunday).The treatment lasted for 2 consecutive *** changes in the range of motion(ROM) of the lumbar vertebrae,visual analogous scale(VAS) score,and the Oswestry disability index(ODI) score of the lumbar vertebrae were assessed before treatment and after 5 and 10 treatment ***:Compared with the data before treatment,the spinal ROM increased after 5 and 10 treatment sessions in the patients with chronic nonspecific low back *** ROM after 10 treatment sessions was remarkably wider than that after 5 treatments,with statistical significance(all P<0.05).Compared with that before treatment,the immediate VAS score showed statistically significant reduction after 5 treatment sessions(P<0.05).Moreover,compared with the score after 5 treatment sessions,the immediate VAS score reduced after 10 treatment sessions,but without any statistical *** 5 and 10 treatment sessions,the ODI score was reduced in the patients and it was significantly different from that before treatment(both P<0.05).Conclusion:Acupuncture at the pain-sensitive points alleviates pain and improves lumbar vertebral function in patients with chronic nonspecific low back ***,further research is needed to confirm whether acupuncture can be a better intervention for ch

关键词： Acupuncture Chronic nonspecific low back pain Acupoint sensitization Pain-sensitive points

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Risk factors of acute coagulation dysfunction after aneurysmal subarachnoid hemorrhage

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Chinese Neurosurgical Journal 2018年第4期4卷 204-209页

作者： Guo-Rong Chen Pei-Sen Yao Chu-Bin Liu Huang-Cheng Shang-Guan Shu-Fa Zheng Liang-Hong Yu Yuan-Xiang Lin Zhang-Ya Lin De-Zhi Kang Department of Neurosurgery The First Affiliated Hospital of Fujian Medical UniversityNO.20 Chazhong RoadTaijiang DistrictFuzhou City 350004FujianChina Department of Neurosurgery The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou City 362000FujianChina

Background: Although coagulopathy have been proved to be a contributor to a poor outcome of aneurysmal subarachnoid hemorrhage (aSAH), the risk factors for triggering coagulation abnormalities have not been studied after aneurysm clipping. Methods: We investigated risk factors of coagulopathy and analyzed the relationship between acute coagulopathy and outcome after aneurysm clipping. The clinical data of 137 patients with ruptured CA admitted to our institution was collected and retrospectively reviewed. Patient demographic data (age, sex), smoking, alcohol use, hypertension, diabetes, Hunt-Hess grade, Fisher grade, operation time, intraoperative total infusion volume, intraoperative blood loss, intraoperative transfusion, intraoperative hemostatic drug treatment, calcium reduction (preoperative free calcium concentration–postoperative free calcium concentration) were recorded. Coagulation was assessed within 24 h. Postoperative hemorrhage and infarction, deep venous thrombosis (DVT), and mortality were analyzed. Results: Coagulopathy was detected in a total of 51 cases (group I), while not in 86 cases (group II). Univariable analysis demonstrated that age, smoking, alcohol use, intraoperative total infusion volume, intraoperative blood loss, intraoperative transfusion, and calcium reduction (≥1.2 mg/dl) were related to coagulopathy. Non-conditional logistic regression analysis showed that age [OR, 1.037 (95% CI, 1.001–1.074);p=0.045] and calcium reduction (≥1.2 mg/dl) [OR, 5.509 (95% CI, 1.900–15.971);p=0.002] were considered as the risk factors for coagulopathy. Hunt-Hess grade [OR, 2.641 (95% CI, 1.079–6.331);p=0.033] and operation time [OR, 0.107 (95% CI, 1.012–0.928);p=0.043] were considered as the risk factors for hypocoagulopathy. There were 6 cases (11.7%) with cerebral infarction in group I, while 6 cases (6.98%) in group II (χ2=0.918, p=0.338). There were 4 cases (7.84%) with rebleeding in group I, while 5 cases (5.81%) in group II (χ2=0.215, p=0.643). Th

关键词： Risk factors Coagulation dysfunction Aneurysmal subarachnoid hemorrhage

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The role of acute normovolemic hemodilution in reducing allogeneic blood transfusion in glioblastoma surgery:a case-control study

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Chinese Neurosurgical Journal 2024年第1期10卷 35-41页

作者： Ping Chen Xin‑Huang Zhang Ying Wang Xian‑Zhong Lin De‑Zhi Kang Qing‑Song Lin Department of Anesthesiology The First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005FujianChina Department of Neurosurgery The First Affiliated Hospital of Fujian Medical UniversityNo.20 Chazhong RdTaijiang DistrictFuzhou 350005FujianChina Department of Neurosurgery Binhai Branch of National Regional Medical CenterThe First Affiliated Hospital of Fujian Medical UniversityFuzhou 350209FujianChina fujian provincial Institutes of Brain Disorders and Brain Sciences The First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005FujianChina fujian provincial Clinical Research Center for Neurological Diseases The First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005FujianChina fujian provincial Key Laboratory of Precision Medicine for Cancer The First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005FujianChina

Background Acute normovolemic hemodilution(ANH)was first introduced in glioblastoma surgery,and its role in reducing allogeneic blood transfusion was investigated in this *** This study enrolled supratentorial glioblastoma patients who received total *** the ANH group,the patients were required to draw blood before the operation,and the blood will be transfused back to the patient during the *** association between ANH and clinical features was *** Sixty supratentorial glioblastoma patients were enrolled in this study,25 patients were allocated in the ANH group,and another 35 patients were included in the control *** dramatically reduced the need for allogeneic blood transfusion(3[12%]vs 12[34.3%],P=0.049),and the blood transfusion per total of patients was dramatically decreased by the application of ANH(0.40±1.15 units vs 1.06±1.59 units,P=0.069).Furthermore,ANH also markedly reduced the requirement of fresh frozen plasma(FFP)transfusion(2[8%]vs 11[31.4%],P=0.030)and the volume of FFP transfusion per total of patients(32.00±114.46 mL vs 115.71±181.00 mL,P=0.033).The complication rate was similar between the two *** ANH was a safe and effective blood conservation technique in glioblastoma surgery.

关键词： Glioblastoma Acute normovolemic hemodilution Surgery Blood transfusion

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