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Transparency and reporting characteristics of randomized controlled trials with chinese herbal medicine formulas interventions

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Frontiers of medicine 2024年第4期18卷 757-761页

作者： Juan Wang Dongni Shi Yaochen Wang Xuanqi Zhang Han Li Xihong Wang Shufeng Luo Lihan Hu Jiashuai Deng Lin Zhang Chung Tai Lau Chung Wah Cheng Fei Han Ji Li Ping Wang Aiping Lyu Zhaoxiang Bian Xuan Zhang Institute for Research and Continuing Education Hong Kong Baptist UniversityShenzhen518057China chinese EQUATOR centre Hong Kong Baptist UniversityHKSAR999077China School of Traditional chinese medicine Tianjin University of Chinese MedicineTianjin301617China School of chinese medicine Beijing University of Chinese MedicineBeijing100105China School of chinese medicine Hong Kong Baptist UniversityHKSAR999077China Department of Pediatrics Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing100053China Xiyuan Hospital China Academy of Chinese Medical SciencesBeijing100091China centre for chinese Herbal medicine Drug Development Hong Kong Baptist UniversityHKSAR999077China

To enhance the clarity and transparency of reporting in trials involving chineseherbal medicine(CHM)formulas,the CONSORT extension specifically tailored for CHM formulas(CONSORT-CHM Formulas 2017)was introduced in 2017[1].This statement,along with its corresponding checklist,outlines key elements essential for reporting in randomized controlled trials(RCTs)related tothe rationale,design,analysis,and interpretation of interventions using CHM *** CONSORT-CHM Formulas 2017 elaborated on 7 of 25 CONSORT checklist items,namely title,abstract and keywords,backgrounds and objectives,participants,interventions,outcomes,generalizability,and interpretation.

关键词： formulas statement rational

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Qingre Lishi Tuihuang therapy for acute icteric hepatitis B: A systematic review

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Journal of Traditional chinese Medical Sciences 2017年第2期4卷 95-105页

作者： Zisong Wang Xueqian Wang Jiajie Zhu Fafeng Cheng Haiqiang Yao Zheng Yang Zengliang Zhang Qingguo wang Beijing University of chinese medicine Beijing 100029China Department of Gastroenterology Wangjing HospitalChina Academy of Traditional Chinese MedicineBeijing 100102China Traditional chinese medicine College Inner Mongolia Medical UniversityHohhot 010110China

Objective:To assess the efficacy of Qingre Lishi Tuihuang therapy (QLTT) for acute icteric hepatitis B ***:Eight electronic databases were searched from inception to December 2016 with no language restrictions for reports of randomized controlled trials evaluating the effect of QLTT treating acute icteric hepatitis *** researchers independently extracted detailed data and assessed methodological *** 5.3.0 software was used to analyze the ***:A total of 13 randomized controlled trials involving 2238 participants were included in this *** methodological quality was generally *** results indicated that supplemented Yinchenhao decoction combined with non-specific treatments was more effective in improving the cure rate (risk ratio =1.80;95% CI 1.21-2.68) and reducing the serum levels of total bilirubin (mean difference =-29.74;95% CI-31.91 to-27.57) and aspartate *** self-made prescriptions conforming to QLTT plus non-specific treatments had beneficial effect for acute icteric hepatitis B in curing this disease (risk ratio =1.48;95% CI 1.27-1.73),as well as for negative seroconversion of HBeAg (risk ratio =1.39;95% CI 1.11-1.74).Supplemented Yinchenhao decoction plus non-specific treatments was more effective than other self-made prescriptions conforming to QLTT in reducing serum total bilirubin ***:Qingre Lishi Tuihuang therapy appears to improve effect based on non-specific treatments for the treatment of acute icteric hepatitis ***,it is premature to draw confirmative conclusions,owing to the poor methodological quality and high clinical heterogeneity of the included *** well-designed clinical randomized controlled trials with large sample sizes should be undertaken.

关键词： Qingre Lishi Tuihuang therapy Acute icteric hepatitis B Systematic review Traditional chinese medicine

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