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Recurrence and survival after surgery for pancreatic cancer with or without acute pancreatitis

World Journal of Gastroenterology 2019年第39期25卷 6006-6015页

作者： Qian Feng Cheng Li Sheng Zhang Chun-Lu Tan Gang Mai Xu-Bao Liu Yong-Hua Chen Department of Pancreatic Surgery West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Rehabilitation Medicine Center West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Xinxiang Medical UniversityXinxiang 453100Henan ProvinceChina Department of Hepatobiliary Surgery Deyang People's HospitalDeyang 618000Sichuan ProvinceChina

BACKGROUND In pancreatic cancer,acute pancreatitis(AP)is a serious morbidity,but its negative effect on long-term outcomes remains to be *** To investigate the effects of AP on the tumor recurrence pattern of pancreatic ductal adenocarcinoma(PDAC)and tumor-specific *** The medical records of 219 patients with curative pancreatectomy for pancreatic cancer at the Pancreatic Surgery Center of West China Hospital from July 2012 to December 2016 were analyzed *** severity of acute pancreatitis was classified according to the Atlanta classification of *** patient demographics and tumor characteristics were *** recurrence was defined as a relapse within 12 mo after *** and disease-free survival and recurrence patterns were *** acute pancreatitis was excluded because its negative effects can be *** Early recurrence in AP group was significantly higher than in non-AP group(71.4%vs 41.2%;P=0.009).Multivariate analysis of postoperative early recurrence showed that moderate or severe AP was an independent risk factor for an early recurrence[odds ratio(OR):4.13;95%confidence interval(CI):1.41-12.10;P=0.01].The median time to recurrence was shorter in patients with AP than in those without(8.4 vs 12.8 mo;P=0.003).Multivariate analysis identified AP as an independent prognostic factor for overall survival[relative risk(RR):2.35;95%CI:1.45-3.83]and disease-free survival(RR:2.24;95%CI:1.31-3.85)in patients with *** Patients with moderate or severe acute pancreatitis developed recurrences earlier than those *** or severe AP is associated with shorter overall and disease-free survival of patients with PDAC.

关键词： Acute pancreatitis Pancreatic ductal adenocarcinoma Recurrence Prognosis Overall survival Disease-free survival

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Three-Dimensional Hierarchical Ternary Nanostructures Bismuth/Polypyrrole/CNTs for High Performance Potassium-lon Battery Anodes

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Chinese Journal of Chemistry 2022年第13期40卷 1585-1591页

作者： Wenming Zhang Xiaoyu Chen Haoshan Xu Yiqun Liu Xiaohui Zhao Zisheng Zhang Ling Li National-Local Joint Engineering Laboratory of New Energy Photoelectric Devices College of Physics Science and TechnologyHebei UniversityBaodingHebei 071002China

In recent years,the anode materials of bismuth(Bi)-based potassium ion batteries with high theoretical capacity and suitable potassium ion insertion potential have attracted extensive ***,due to the volume expansion of Bi,the performance of Bi-based anode materials is not ideal during potassium ion(de)*** order to solve these problems,we report a three-dimensional(3D)ternary bismuth nanoparticles/conductive polymers/carbon nanotubes(Bi/PPy/CNT)hybrid anode material for K-ion *** a current density of 100 mA·g^(-1),its reversible capacity reaches 302 mAh·g^(-1) after 200 cycles,while it reaches 195.7 mAh·g^(-1) after 600 cycles at 1 A·g^(-1).Its excellent performance is attributed to the hydrogel network which provides a range of electron transport networks and high *** nanotubes are used as electron enhancers to reduce the volume expansion of Bi particles during the *** study provides a prerequisite for expanding the application of 3D ternary materials.

关键词： Bismuth Nanostructures Conducting materials Potassium ion battery Energy storage

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Multi-source information fused generative adversarial network model and data assimilation based history matching for reservoir with complex geologies

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Petroleum Science 2022年第2期19卷 707-719页

作者： Kai Zhang Hai-Qun Yu Xiao-Peng Ma Jin-Ding Zhang Jian Wang Chuan-Jin Yao Yong-Fei Yang Hai Sun Jun Yao Jian Wang School of Petroleum Engineering China University of Petroleum(East China)QingdaoShandong266580China School of Science China University of Petroleum(East China)QingdaoShandong266580China Shengli Oil Field Exploration and Development Research Institute DongyingShandong266071China

For reservoirs with complex non-Gaussian geological characteristics,such as carbonate reservoirs or reservoirs with sedimentary facies distribution,it is difficult to implement history matching directly,especially for the ensemble-based data assimilation *** this paper,we propose a multi-source information fused generative adversarial network(MSIGAN)model,which is used for parameterization of the complex *** MSIGAN,various information such as facies distribution,microseismic,and inter-well connectivity,can be integrated to learn the geological *** two major generative models in deep learning,variational autoencoder(VAE)and generative adversarial network(GAN)are combined in our *** the proposed MSIGAN model is integrated into the ensemble smoother with multiple data assimilation(ESMDA)method to conduct history *** tested the proposed method on two reservoir models with fluvial *** experimental results show that the proposed MSIGAN model can effectively learn the complex geological features,which can promote the accuracy of history matching.

关键词： Multi-source information Automatic history matching Deep learning Data assimilation Generative model

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Thermal-water-salt coupling process of unsaturated saline soil under unidirectional freezing

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Journal of Mountain Science 2023年第2期20卷 557-569页

作者： LUO Chong-liang YU Yun-yan ZHANG Jing TAO Jing-yan OU Qing-jie CUI Wen-hao School of Civil Engineering Lanzhou Jiaotong UniversityLanzhou 730070China School of Civil Engineering Hexi UniversityZhangye 734000China State Key Laboratory of Frozen Soil Engineering Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China

Salinization and desertification are closely related to water-salt migration caused by a temperature *** on the Darcy Law of unsaturated soils,the law of energy conservation and the law of mass conservation,the thermal-water-salt coupling mathematical model of unsaturated frozen saline soil was *** model considered the latent heat of phase change,crystallization impedance,crystallization consumption and complete precipitation of solute crystallization in *** order to verify the rationality of the model,the unidirectional freezing test of unsaturated saline soil was carried out in an open system with no-pressure water supplement to obtain the spatial distribution of temperature,moisture and salt in the saline ***,numerical simulations are implemented with the assistance of COMSOL *** of the model is illustrated by comparisons between the simulation and experimental *** results demonstrated that the temperature within saline soil changes with time and can be divided into three stages,namely quick freezing stage,transitional stage and stable *** water and salt contents in the freezing zone are layered,with peak values at the freezing *** coupled model could reveal the heat-mass migration mechanism of unsaturated frozen saline soil and dynamically describe the freezing depth and the movement law of the freezing front,ice and salt crystal formation mechanism,and the change law of thermal conductivity and permeability coefficient.

关键词： Unsaturated sulfate saline soil Watersalt migration Crystallization latent heat Crystallization impedance Mathematical model

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轧制Mo-14%Re合金的显微组织和室温拉伸性能

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稀有金属材料与工程 2023年第8期52卷 2746-2756页

作者：何朝军胡平邢海瑞杨帆张向阳林小辉华兴江白润张文王快社西安建筑科技大学冶金工程学院陕西西安710055 西安建筑科技大学功能材料加工国家地方联合工程研究中心陕西西安710055 西北有色金属研究院陕西西安710016

为了进一步了解轧制Mo-14%Re合金的显微组织和室温拉伸性能,采用扫描电镜(SEM)和高分辨电子背散射衍射(EBSD)研究了轧制Mo-14%Re合金的显微组织和断口形貌。采用Channel 5软件分析了轧制Mo-14%Re合金在不同退火温度下的组织演变。结果表... 详细信息

为了进一步了解轧制Mo-14%Re合金的显微组织和室温拉伸性能,采用扫描电镜(SEM)和高分辨电子背散射衍射(EBSD)研究了轧制Mo-14%Re合金的显微组织和断口形貌。采用Channel 5软件分析了轧制Mo-14%Re合金在不同退火温度下的组织演变。结果表明,随着退火温度的升高,Mo基体相和ReO_(3)相的施密特因子逐渐减小。织构强度迅速增加,极图上的晶体取向强度从6.51增加到10.18。轧制Mo-14%Re合金的初始再结晶发生在1100℃,在此退火温度下,合金中富稀土ReO_(3)相均匀析出,导致拉伸过程中应力分布均匀,Mo基体相和ReO_(3)相表现出明显的晶体取向,ReO_(3)相晶界主要为大角度晶界,使得断后伸长率达到最大值33.5%。拉伸断裂的韧窝数量最多且最大。此外,还研究了断裂过程中微孔的形成、聚集、生长和裂纹扩展。

关键词： Mo-14%Re合金室温拉伸初始再结晶微观结构演化裂纹扩展

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Plasmonic Cu_(27)S_(24)nanocages for novel solar photothermal nanoink and nanofilm

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Nano Research 2022年第4期15卷 3161-3169页

作者： Min Xi Longchang Xu Nian Li Shudong Zhang Zhenyang Wang Institute of Solid State Physics and Key Laboratory of Photovoltaic and Energy Conservation Materials Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China The Key Laboratory Functional Molecular Solids Ministry of Education Anhui Normal UniversityWuhu 241002China School of Mechatronics and Vehicle Engineering Chongqing Jiaotong UniversityChongqing 400074China

Copper sulfide(Cu_(x)S)as a plasmonic solar photothermal semiconductor material that expands the light collection range by altering localized surface plasmon resonance(LSPR)to the near-to mid-infrared(IR)spectral *** versatile synthesis strategies of Cu_(x)S nanostructure offer its variability of morphology and provide additional freedom in tuning the optical ***,nanocage(or nanoshell)has hybridized plasmon resonances as a result of super-positioned nanosphere and nanocavity,which extends its receiving range of solar spectrum and increases light-to-heat conversion ***,we offer novel“nanoink”and“nanofilm”developed from colloidal Cu_(27)S_(24)nanocages with excellent solar photothermal *** combining experimental measurement and theoretical calculation,we estimated the optical properties of covellite Cu_(27)S_(24).And based on obtained dielectric functions,we then calculated its solar photothermal performance,which was further validated by our experimental *** simulation results showed that hollow Cu_(27)S_(24)nanocages have excellent solar photothermal performance,and exhibit much higher solar photothermal conversion efficiency than solid Cu_(27)S_(24)nanospheres.

关键词： plasmonics solar photothermal hybridized plasmon Cu_(27)S_(24)nanocages

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A generic high-throughput microstructure classification and quantification method for regular SEM images of complex steel microstructures combining EBSD labeling and deep learning

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Journal of Materials Science & Technology 2021年第34期93卷 191-204页

作者： Chunguang Shen Chenchong Wang Minghao Huang Ning Xu Sybrand van der Zwaag Wei Xu State key laboratory of rolling and automation Northeastern UniversityShenyangLiaoning 110819China Novel Aerospace Materials Group Faculty of Aerospace EngineeringDelft University of Technology2629 HS Delftthe Netherlands

We present an electron backscattered diffraction(EBSD)-trained deep learning(DL)method integrating traditional material characterization informatics and artificial intelligence for a more accurate classification and quantification of complex microstructures using only regular scanning electron microscope(SEM)*** this method,EBSD analysis is applied to produce accurate ground truth data for guiding the DL model *** U-Net architecture is used to establish the correlation between SEM input images and EBSD ground truth data using only small experimental *** proposed method is successfully applied to two engineering steels with complex microstructures,i.e.,a dual-phase(DP)steel and a quenching and partitioning(Q&P)steel,to segment different phases and quantify phase content and grain ***,once properly trained the method can also produce quasi-EBSD maps by inputting regular SEM *** good generality of the trained models is demonstrated by using DP and Q&P steels not associated with the model ***,the method is applied to SEM images with various states,i.e.,different imaging modes,image qualities and magnifications,demonstrating its good robustness and strong application ***,the visualization of feature maps during the segmenting process is utilised to explain the mechanism of this method’s good performance.

关键词： Microstructure quantification Deep learning Electron backscatter diffraction Small sample problem

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Clinical effects of acupuncture therapy for vascular dementia

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Neural Regeneration Research 2011年第3期6卷 193-199页

作者： Zhao, Lei Guo, Yi Xiong, Jun Wang, Wei Du, Yuanhao Yan, Lijuan Tianjin Univ Tradit Chinese Med Acupuncture & Moxibust Coll Tianjin 300193 Peoples R China Tianjin Univ Tradit Chinese Med Dept Acupuncture & Moxibust Affiliated Hosp 1 Tianjin 300193 Peoples R China

OBJECTIVE： To evaluate clinical acupuncture treatment studies for vascular dementia, as well as to collect high-quality evidence related to clinical acupuncture treatment for clinical diagnosis. DATA SOURCES： PubMed database （1966-2010）, Embase database （1986-2010）, Cochrane Library （Issue 1,2010）, Chinese Biomedical Literature Database （1979-2010）, China HowNet database （1979-2010）, VlP Journals Database （1989-2010）, and Wanfang database （1998-2010） were analyzed by computer.

关键词： acupuncture vascular dementia clinical evidence traditional Chinese medicine

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New type flooding systems in enhanced oil recovery

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Chinese Chemical Letters 2009年第10期20卷 1251-1254页

作者： Xin Ping Li Li Yu Yong Qiang Ji Bo Wu Gan Zuo Li Li Qiang Zheng Key Laboratory of Colloid and Interfacial Chemistry of Ministry of Education in Shandong University Jinan Shandong 250100 China

Wormlike micelles, obtained in anionic surfactam sodium oleate （NaOA） solutions in the presence of sodium phosphate （Na3PO4）, were studied using the steady and dynamic rheological methods. The laboratory simulation flooding experiments were used to investigate the effects of flooding for the wormlike micelles system. The results show that the oil recovery is 32.7%. This flooding system is a new type and has high activity with a low cost.

关键词： Wormlike miceUes Rheology Oil recovery

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Comparative proteomic profiles of resistant/susceptible cucumber leaves in response to downy mildew infection

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Horticultural Plant Journal 2021年第4期7卷 327-340页

作者： Chengzhen Sun Xiaofei Song Jinshuang Zheng Xiaoli Li Zhihong Feng Liying Yan Hebei Key Laboratory of Horticultural Germplasm Excavation and Innovative Utilization QinhuangdaoHebei 066004China College of Horticulture Science and Technology Hebei Normal University of Science and TechnologyQinhuangdaoHebei 066004China

Downy mildew is a serious disease in cucumber production worldwide,which is caused by Pseudoperonospora cubensis(Berk.&Curt.)*** the mechanism of cucumber response to downy mildew infection is important for breeding improvement and production;however,the research remains largely elusive.A comparative proteomic approach was used to reveal the differential accumulation of the proteomes from leaves of cucumber(susceptible line and resistant line)that were inoculated with *** or not by two-dimensional electrophoresis and MALDI-TOF/TOF MS.A total of 76 protein spots were successfully identified with significant changes in abundance(>2-fold,P<0.05)in downy mildew infected or not leaves for the susceptible line and resistant *** the functional annotation,these proteins were classified into 8 groups including photosynthesis(29%),energy and metabolism(29%),cell rescue and defense(17%),and protein biosynthesis,folding and degradation(13%),unclassified(7%),nucleotide metabolism(3%),signal transduction(1%)and cellular process(1%).Among the 17 differentially expressed proteins between the resistant and susceptible cucumber line,most of the protein spots were concentrated in cell rescue and defense(4)and energy and metabolism(4).Moreover,a schematic diagram containing majority of the metabolic pathways of cucumber leaves in response to downy mildew was *** network revealed the positive effect of several functional components in cucumber seedlings’resistant to downy mildew such as accumulation of energy supply and resistance-related proteins,hastened protein metabolism and photorespiratory,inhibited photosynthesis,and triggered photosystem repair and programmed cell *** together,these results have advanced a further understanding of the key metabolic pathways of cucumber resistance to downy mildew and pathogen control in the proteomic level.

关键词： Defense response Downy mildew Proteomics Cucumber

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