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Influence of scattering of SH-waves in dynamic interaction of shear wall with soil layers

Earthquake Engineering and Engineering Vibration 2020年第3期19卷 583-595页

作者： Shashi Kumar Swapan Kumar Chakraborty Department of Mathematics Sarala Birla UniversityRanchi 835103India Department of Applied Mathematics Cambridge Institute of TechnologyRanchi 835103India Department of Mathematics Birla Institute of TechnologyMesraRanchi 835215India

The dynamic soil-structure interaction of a shear wall embedded in elastic isotropic and homogeneous soil layers underlain by bedrock,subjected to SH waves,is modeled in the present *** soil layers consist of irregular interfaces and it has been shown that the scattering due to the roughness of the layers has significant effect on the displacement of both the foundation and the shear *** demonstrate the phenomena indirect boundary element method(IBEM)has been used on the basis of its validation in previous problems of similar *** system response is compared with the analytical solution of the same type of model for vertically propagating incident SH *** is observed that for the low frequency of wave,displacement is abruptly high,and as a result the combination of shear wall and foundation perceives *** thickness of the soil layer,mass of the shear wall,stiffness of the bedrock and the soil layers all affects the system frequency and displacement.

关键词： soil dynamic interaction

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Comparative Multivariate Analysis of Codon and Amino Acid Usage in Three Leishmania Genomes

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Genomics, Proteomics & Bioinformatics 2011年第6期9卷 218-228页

作者： Nutan Chauhan Ambarish Sharan Vidyarthi Raju Poddar Department of Biotechnology Birla Institute of TechnologyMesra Ranchi-835215 India

Multivariate analysis of codon and amino acid usage was performed for three Leishmania species, including L. donovani, L. infantum and L. major. It was revealed that all three species are under mutational bias and translational selection. Lower GC12 and higher GC3s in all three parasites suggests that the ancestral highly expressed genes （HEGs）, compared to lowly expressed genes （LEGs）, might have been rich in AT-content. This also suggests that there must have been a faster rate of evolution under GC-bias in LEGs. It was observed from the esti- mation of synonymous/non-synonymous substitutions in HEGs that the HEG dataset of L. donovani is much closer to L. major evolutionarily. This is also supported by the higher ds value as compared to ds between L. donovani and L. major, suggesting the conservation of synonymous codon positions between these two species and the role of translational selection in shaping the composition of protein-coding genes.

关键词： Leishmania relative synonymous codon usage multivariate analysis hydropathy aromaticity

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In vitro evaluation of anti-acetylcholinesterase and free radical scavenging potential of leaf extracts of some selected medicinal plants

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Asian Pacific Journal of Tropical Biomedicine 2019年第2期9卷 60-65页

作者： Annie Jessica Toppo Sheela Chandra Dhruv Jha Papiya Mitra Mazumder Department of Bio-Engineering Birla Institute of Technology Department of Pharmaceutical Sciences and Technology Birla Institute of Technology

Objective: To evaluate the phytochemical present in various solvent extracts from leaves of Ocimum sanctum(L.), Swertia chirayita(L.), Butea monosperma(Lam.) and Stevia rebaudiana(Bert.) as well as antioxidant and anticholinergic activities employing different in vitro models. Methods: Total phenol content of diethyl ether, chloroform and methanolic extracts obtained from leaves of different medicinal plants was determined by Folin-Ciocalteau's spectrophotometric method. Moreover, antioxidant and anticholinergic studies were conducted by four different in vitro methods which included diphenyl picrylhydrazyl radical scavenging, 2,2-azinobis(3-ethylbezoline-6-sulphonic acid), reducing activity by ferrous reduced antioxidant power and anti-acetylcholinesterase assay, in order to ensure pharmacological potential of the plants. Results: The methanolic leaf extract of Ocimum sanctum showed the highest total phenol content which was(21.13±1.04) GAE/g DW and antioxidant activities compared to other plants with the IC50 value of 40.43 μg/mL in diphenyl picrylhydrazyl radical scavenging assay and 53.5 μg/mL in 2,2-azinobis(3-ethylbezoline-6-sulphonic acid) assay as well as metal ion reduced by(78.22±0.38) TE/g DW in ferrous reduced antioxidant power assay. The inhibition percentage of the anti-acetylcholinesterase assay was(94.22±0.26)%. Conclusions: The results of our current study show that Ocimum sanctum leaf is the most significant source of phytochemicals that possesses antioxidant and anticholinergic properties. However, further investigation on isolation and characterization of active compound which is responsible for the pharmacological potential is needed.

关键词： DPPH assay Antioxidant Free radical Anti-acetylcholinesterase Phenolics content

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Morphoanatomic, physicochemical, and phytochemical standardization with HPTLC fingerprinting of aerial parts of Aerva lanata (Linn) Juss ex Schult

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Journal of Traditional Chinese Medical Sciences 2015年第1期2卷 39-44页

作者： Yuhao Zhao Deepak Kumar D.N.Prasad Rajesh KSingh Yanxu Ma School of Traditional Chinese Medicine Capital Medical UniversityBeijing 100069China Shivalik College of Pharmacy NangalRoparPunjab 140126India Department of Orthopedics Beijing Traditional Chinese Medicine HospitalCapital Medical UniversityBeijing 100010China

Objective:Aerva lanata (Linn) Juss ex Schult,family Amaranthaceae,is a common wayside *** herb is accepted by the Ayurvedic Formulary of *** study was undertaken to establish morphoanatomic and physiochemical standards of ***:Leaf constants and high-performance thin layer chromatography fingerprint profiles of *** were *** and conclusion:The physico-chemical,morphologic,and histologic parameters presented in this paper may be proposed as standards to establish the authenticity of *** and help differentiate it from other species such as Aerva tomentosa.

关键词： Aerva lanata Amaranthaceae Phytochemical Physicochemical Morphoanatomic

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