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Wide Stopband Substrate Integrated Waveguide Filter Using Bisection and Trisection Coupling in Multilayer

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Chinese Journal of Electronics 2024年第2期33卷 436-442页

作者： Peng CHU Jianguo FENG Peng ZHU Lei GUO Long ZHANG Leilei LIU Guoqing LUO Ke WU College of Electronic and Optical Engineering Nanjing University of Posts and Telecommunications National and Local Joint Engineering Laboratory of RF Integration and Micro-Assembly Technology School of Information and Communication Engineering Dalian University of Technology Guangdong Provincial Key Laboratory of Optoelectronic Information Processing Chips and Systems Sun Yat-sen University College of Electronics and Information Engineering Shenzhen University School of Electronics and Information Hangzhou Dianzi University Poly-Grames Research Center Polytechnique Montreal

This article presents a highly efficient method for substrate-integrated-waveguide（SIW） filters to achieve very wide stopbands. By employing the proposed trisection slots in addition to the bisection slots as the inter-coupling structures, all spurious modes below TE505 of a SIW filter working in the fundamental mode TE101（f0）can be eliminated without requiring additional structure or complex theoretical analysis, without affecting the design of the fundamental passbands, and without degrading the performance of the filters. For verification, two prototype filters are designed, fabricated, and measured with wide stopbands up to 4.15f0 and 4.83f0, respectively. The proposed technique could facilitate the development of high-performance wide-stopband SIW filters for microwave/wireless circuits and systems.

关键词： Microwave measurement Couplings Filters Prototypes Nonhomogeneous media Microwave theory and techniques Microwave circuits

Two-grid Method of Expanded Mixed Finite Element Approximations for Parabolic Integro-differential Optimal Control Problems

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Acta Mathematicae Applicatae Sinica 2024年

作者： Yan-ping CHEN Jian-wei ZHOU Tian-liang HOU School of Science Nanjing University of Posts and Telecommunications School of Mathematics and Statistics Linyi University School of Mathematics and Statistics Beihua University

This paper aims to construct a two-grid scheme of fully discretized expanded mixed finite element methods for optimal control problems governed by parabolic integro-differential equations and discuss a priori error estimates. The state variables and co-state variables are discretized by the lowest order Raviart-Thomas mixed finite element, and the control variable is approximated by piecewise constant functions. The time derivative is discretized by the backward Euler method. Firstly, we define some new mixed elliptic projections and prove the corresponding error estimates which play an important role in subsequent convergence ***, we derive a priori error estimates for all variables. Thirdly, we present a two-grid scheme and analyze its convergence. In the two-grid scheme, the solution of the parabolic optimal control problem on a fine grid is reduced to the solution of the parabolic optimal control problem on a much coarser grid and the solution of a decoupled linear algebraic system on the fine grid and the resulting solution still maintains an asymptotically optimal accuracy. At last, a numerical example is presented to verify the theoretical results.

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Rational design of biodegradable semiconducting polymer nanoparticles for NIR-II fluorescence imaging-guided photodynamic therapy

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Nano Research 2024年第6期17卷 5399-5408页

作者： Xuxuan Gu Jinlong Shen Zhiwei Xu Wenqi Wang Ying Wu Wen Zhou Chen Xie Quli Fan State Key Laboratory of Organic Electronics and Information Displays&Institute of Advanced Materials(IAM) Nanjing University of Posts&Telecommunications9 Wenyuan RoadNanjing 210023China

Semiconducting polymer nanoparticles(SPNs)have shown great promise in second near-infrared window(NIR-II)***,the issue of long metabolic time significantly restricts the clinical application of *** this study,we rationally designed a biodegradable SPN(BSPN50)for NIR-II fluorescence imaging-guided photodynamic therapy(PDT).BSPN50 is prepared by encapsulating a biodegradable SP(BSP50)with an amphiphilic copolymer ***50 is composed of NIR-II fluorescent diketopyrrolopyrrole(DPP)segment and degradable poly(phenylenevinylene)(PPV)segment with the ratio of 50/***50 has both satisfactory degradability under myeloperoxidase(MPO)/hydrogen peroxide(H_(2)O_(2))and NIR-II fluorescence emission upon 808 nm laser ***,BSPN50 shows good photodynamic efficacy under 808 nm laser ***50 shows a faster degradation rate than BSPN100 which has no PPV segment both in vitro and in *** addition,BSPN50 can effectively diagnose tumor via NIR-II fluorescence imaging and inhibit the tumor growth by ***,our study provides a rational approach to construct biodegradable nanoplatforms for efficient tumor NIR-II phototheranostics.

关键词： near-infrared(NIR)-II fluorescence imaging semiconducting polymer nanoparticles photodynamic therapy tumor imaging

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 458-474页

作者： Wei Ding Wei-Wei Chen Yi-Qin Wang Xue-Zhong Xu Yi-Bo Wang Yong-Min Yan Yu-Lin Tan Department of General Surgery Wujin Hospital Affiliated with Jiangsu UniversityChangzhou 213003Jiangsu ProvinceChina Changzhou Medical Center Nanjing Medical UniversityChangzhou 213017Jiangsu ProvinceChina Department of General Surgery The Wujin Clinical College of Xuzhou Medical UniversityChangzhou 213003Jiangsu ProvinceChina

BACKGROUND Gastric cancer(GC)is a prevalent malignant tumor of the gastrointestinal ***710 is a transcription factor(TF),and zinc finger protein 710(ZNF710)-AS1-201 is an immune-related long noncoding RNA(lncRNA)that is upregulated in GC *** To assess the correlation between ZNF710-AS1-201 and immune microenvir-onment features and to investigate the roles of ZNF710-AS1-201 in the invasion and metastasis processes of GC *** We obtained data from The Cancer Genome Atlas and Wujin *** assessed cell growth,migration,invasion,and programmed cell death using cell counting kit-8,EdU,scratch,Transwell,and flow cytometry *** real-time polymerase chain reaction(qRT-PCR)was used to identify the potential downstream targets of *** In GC tissues with low ZNF710-AS1-201 expression,immunoassays detected significant infiltration of various antitumor immune cells,such as memory CD8 T cells and activated CD4 T *** the low-expression group,the half-maximal inhibitory concentrations(IC_(50)s)of 5-fluorouracil,cisplatin,gemcitabine,and trametinib were lower,whereas the IC_(50)s of dasatinib and vorinostat were *** malignant degree of GC was higher and the stage was later in the high-expression ***,patients with high expression of ZNF710-AS1-201 had lower overall survival and disease-free survival *** vitro,the overexpression of ZNF710-AS1-201 greatly enhanced growth,metastasis,and infiltration while suppressing cell death in HGC-27 *** contrast,the reduced expression of ZNF710-AS1-201 greatly hindered cell growth,enhanced apoptosis,and suppressed the metastasis and invasion of MKN-45 *** expression changes in ZNF710 were significant,but the corresponding changes in isocitrate dehydrogenase-2,Semaphorin 4B,ARHGAP10,RGMB,hsa-miR-93-5p,and ZNF710-AS1-202 were not consistent or statistically significant after overexpression or knockdown of ZNF710-AS1-201,as determined by ***

关键词： Gastric cancer ZNF710-AS1-201 Proliferation Metastasis Invasion Apoptosis

Distributed Nash Equilibrium Seeking Strategies Under Quantized Communication

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IEEE/CAA Journal of Automatica Sinica 2024年第1期11卷 103-112页

作者： Maojiao Ye Qing-Long Han Lei Ding Shengyuan Xu Guobiao Jia IEEE the School of Automation Nanjing University of Science and TechnologyNanjing 210094China the School of Science Computing and Engineering TechnologiesSwinburne University of TechnologyMelbourne VIC 3122Australia the Institute of Advanced Technology Nanjing University of Posts and TelecommunicationsNanjing 210023China

This paper is concerned with distributed Nash equi librium seeking strategies under quantized communication. In the proposed seeking strategy, a projection operator is synthesized with a gradient search method to achieve the optimization o players' objective functions while restricting their actions within required non-empty, convex and compact domains. In addition, a leader-following consensus protocol, in which quantized informa tion flows are utilized, is employed for information sharing among players. More specifically, logarithmic quantizers and uniform quantizers are investigated under both undirected and connected communication graphs and strongly connected digraphs, respec tively. Through Lyapunov stability analysis, it is shown that play ers' actions can be steered to a neighborhood of the Nash equilib rium with logarithmic and uniform quantizers, and the quanti fied convergence error depends on the parameter of the quan tizer for both undirected and directed cases. A numerical exam ple is given to verify the theoretical results.

关键词： Consensus distributed Nash equilibrium seeking projected gradient play quantized communication

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Transfer learning enhanced graph neural network for aldehyde oxidase metabolism prediction and its experimental application

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Acta Pharmaceutica Sinica B 2024年第2期14卷 623-634页

作者： Jiacheng Xiong Rongrong Cui Zhaojun Li Wei Zhang Runze Zhang Zunyun Fu Xiaohong Liu Zhenghao Li Kaixian Chen Mingyue Zheng Drug Discovery and Design Center State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China university of Chinese Academy of Sciences Beijing 100049China College of Computer and Information Engineering Dezhou UniversityDezhou 253023China AI Department Suzhou Alphama Biotechnology Co.Ltd.Suzhou 215000China Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and TechnologyShanghaiTech UniversityShanghai 200031China State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjing 210023China

Aldehyde oxidase(AOX)is a molybdoenzyme that is primarily expressed in the liver and is involved in the metabolism of drugs and other ***-mediated metabolism can result in unexpected outcomes,such as the production of toxic metabolites and high metabolic clearance,which can lead to the clinical failure of novel therapeutic *** models can assist medicinal chemists in rapidly evaluating the AOX metabolic risk of compounds during the early phases of drug discovery and provide valuable clues for manipulating AOX-mediated metabolism *** this study,we developed a novel graph neural network called AOMP for predicting AOX-mediated *** integrated the tasks of metabolic substrate/non-substrate classification and metabolic site prediction,while utilizing transfer learning from 13C nuclear magnetic resonance data to enhance its performance on both *** significantly outperformed the benchmark methods in both cross-validation and external *** AOMP,we systematically assessed the AOX-mediated metabolism of common fragments in kinase inhibitors and successfully identified four new scaffolds with AOX metabolism liability,which were validated through in vitro ***,for the convenience of the community,we established the first online service for AOX metabolism prediction based on AOMP,which is freely available at https://***.

关键词： Drugmetabolism Aldehyde oxidase Transferlearning Graph neural network Kinase inhibitor

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BiVO_(4)/CoPc S型异质结的构建及其光热增强光催化性能

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Science China Materials 2024年第2期67卷 550-561页

作者：龙子洋郑相阳史海峰 School of Science Jiangnan UniversityWuxi 214122China National Laboratory of Solid State Microstructures Nanjing UniversityNanjing 210093China

光热催化降解去除污染物对解决环境问题具有独特的优势.本文通过水热法结合超声处理的方法合成了BiVO4/CoPc S型异质结光热催化材料.实验结果表明,BVO-1%CoPc在10分钟内对四环素对降解率可达76%,相比钒酸铋单质提高了1.8倍.进一步的红... 详细信息

光热催化降解去除污染物对解决环境问题具有独特的优势.本文通过水热法结合超声处理的方法合成了BiVO4/CoPc S型异质结光热催化材料.实验结果表明,BVO-1%CoPc在10分钟内对四环素对降解率可达76%,相比钒酸铋单质提高了1.8倍.进一步的红外热成像仪表明酞菁钴(CoPc)的光热效应可以提高反应体系的温度.同时,研究人员还发现降解后的中间产物毒性显著降低.光致发光光谱的结果表明,合成的复合材料可以增强光生载流子的分离能力.基于捕获实验、能带结构和原位XPS等研究结果,我们提出了光生电荷在合成的催化剂中的S型传输机制.本工作为设计和开发用于去除有机污染物的S型光热催化材料提供了一种可行的策略.

关键词： BiVO_(4) CoPc photothermal effect S-scheme heterojunction tetracycline

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Upconversion electroluminescence enabled by plasmonic tunnel junctions

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Science China Technological Sciences 2024年

作者： XING GuanSheng LIN ZhaoRan WANG XiangFu CHEN Bing School of Chemistry and Life Sciences Nanjing University of Posts and Telecommunications College of Electronic and Optical Engineering and College of Flexible Electronics (Future Technology) Nanjing University of Posts and Telecommunications

The integration of plasmonic materials with luminescence phosphors or semiconductors represents a burgeoning frontier in nanotechnology, aimed at enhancing the optical properties of these materials for advanced photonic applications [1–3]. Among them, the development of electroluminescence induced by plasmonic tunnel junctions (TJs) has garnered significant attention due to the potential to impact a wide range of scientific and technological fields, driving forward innovations in lighting, energy, redox chemistry, and so forth [4–6].

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Self-healable gels in electrochemical energy storage devices

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Nano Research 2024年第4期17卷 3302-3323页

作者： Yang Li PeiPei Ding Yuzhe Gu Sheng Qian Yuncong Pang Lele Wang Jiayang Feng Baoguang Liu Qi Wan Ping Li Zhiwei Liu College of Electronic and Optical Engineering&College of Flexible Electronics(Future Technology) Nanjing University of Posts&Telecommunications(NJUPT)Nanjing 210023China State Key Laboratory of Organic Electronics and Information Displays&Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Nanjing University of Posts and Telecommunications(NJUPT)Nanjing 210023China College of Materials Science&Engineering Beijing University of TechnologyBeijing 100124China Beijing Advanced Innovation Center for Materials Genome Engineering Institute for Advanced Materials and TechnologyUniversity of Science and Technology BeijingBeijing 100083China Pillar of Engineering Product Development Singapore University of Technology and DesignSingapore 487372Singapore School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China

In the green energy and carbon-neutral technology,electrochemical energy storage devices have received continuously increasing attention ***,due to the unavoidable volume expansion/shrinkage of key materials or irreversible mechanical damages during application,the stability of energy storage and delivery as well as the lifetime of these devices are severely shortened,leading to serious performance degradation or even safety ***,the utilization of self-healable gels into electrochemical energy storage devices,such as electrodes,binders,and electrolytes,is proven as an effective method to realize long-term stable operation of these devices via the self-repairing of mechanical and electrochemical ***,this review first summarizes the feature and fabrication of different gels,paying special attention to hydrogels,organohydrogels,and ***,basic concepts and figure of merit of self-healable gels are analyzed with a detailed discussion at the healing mechanisms,from reversible dynamic bonds to physical molecular diffusion,and to external healing *** we introduce all the important parts of electrochemical energy storage devices,which could be replaced by healable gels to enhance the durability,including electrodes,binders,and ***,the critical challenges and future perspectives regarding the future development of healable gels based high-performance electrochemical energy storage devices or electronics are provided.

关键词： self-healable gels healing mechanisms electrodes binders gel electrolytes