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World Journal of Gastroenterology 2006年第24期12卷 3854-3858页

作者： Wei Ma zuo-ren wang Lei Shi Yue Yuan Department of Hepatobiliary.Surgery First Hospital of Xi'an Jiaotong University Xi'an 710061 Shaanxi Province China Department of Pharmacy First Hospital of Xi'anJiaotong University Xi'an 710061 Shaanxi Province China

AIM： To explore the expression of macrophage inflammatory protein-1α （MIP-1α） in Kupffer cells （KCs） following liver ischemia/reperfusion injury IRI in rats. METHODS： Forty male SD rats were divided randomly into five groups. A model of partial warm ischemia/ reperfusion injury in the rat liver was established. KCs were isolated and incubated one hour, six hours, 12 h, and 24 h after the reperfusion. Tumor necrosis factor alpha （TNF-α） and interleukin-lbeta （IL-1β） in the supernatants were measured by ELISA. MIP-1α in KCs was detected by immunocytochemical and RT-PCR. RESULTS： No or few MIP-1α protein and mRNA were expressed in the KCs of the control group. Its expression in the IRI group had a significant increase after the reperfusion （P 〈 0.05）, which was contrary to the control group. CONCLUSION： The active behavior of the MIP-1α gene in KCs following liver ischemia/reperfusion injury is assumed to be one of the major causes for the hepatic ischemia/reperfusion injury.

关键词： Liver Ischemia/reperfusion Kupffer cell Macrophage inflammatory protein-1α

Expression of angiostatin cDNA in human gallbladder carcinoma cell line GBC-SD and its effect on endothelial proliferation and growth

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World Journal of Gastroenterology 2006年第17期12卷 2762-2766页

作者： Ding-Zhong Yang Jing He Ji-Cheng Zhang zuo-ren wang Department of Surgery The First Hospital Xi'an Jiaotong University Xi'an 710065 Shannxi Province China Deparment of Pharmacology University of Texas Medical Branch Galveston 77555 Texas State United States Department of surgery Union Hospital Fujian Medical University Fuzhou 350001 Fujian Province China Department of surgery The First Hospital Xi' an Jiaotong University Xi'an 710065 Shannxi Province China

AIM： To explore the influence of angiostatin up-regulation on the biologic behavior of gallbladder carcinoma cells in vitro and in vitro, and the potential value of angiostatin gene therapy for gallbladder carcinoma. METHODS： A eukaryotic expression vector of pcDNA3.1（＋） containing murine angiostatin was constructed and identified by restriction endonuclease digestion and sequencing. The recombinant vector pcDNA3.1-angiostatin was transfected into human gallbladder carcinoma cell line GBC-SD with Upofectamine 2000, and paralleled with the vector and mock control. The resistant clone was screened by G418 filtration. Angiostatin transcription and protein expression were examined by RT-PCR, immunofluorescence and Western-blot. The supernatant was collected to treat endothelial cells. Cell proliferation and growth in vitro were observed under microscope. RESULTS： Murine angiostatin cDNA was successfully cloned into the eukaryotic expression vector pcDNA3.1 （＋）. AFter 14 d of transfection and selection with G418, macroscopic resistant cell cloning was formed in the experimental group transfected with pcDNA 3.1（＋）-angiostatin and vector control. But untreated cells died in the mock control. Angiostatin was detected by RT-PCR and protein expression was detected in the experimental group by immunofluorescence and Western-blot. Cell proliferation and growth in v/tro in the three groups were observed respectively under microscope. No significant difference was observed in the growth speed of GBC- SD cells between groups that were transfected with and without angiostatin. After treatment with supernatant, significant differences were observed in endothelial cell （ECV-304） growth in vitro. The cell proliferation and growth were inhibited. CONCLUSION： Angiostatin does not directly inhibit human gallbladder carcinoma cell proliferation and growth in vitro, but the secretion of angiostatin inhabits endothelial cell proliferation and growth.

关键词： Angiostatin Gallbladder carcinoma Endothelial cell

Zero-Dynamics Attacks for Multi-Agent Systems Without Velocity Measurements

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Journal of Systems Science & Complexity 2024年第5期37卷 1809-1831页

作者： GAO Jinming wang Yijing zuo Zhiqiang ZHANG Wentao Tianjin Key Laboratory of Intelligent Unmanned Swarm Technology and System School of Electrical and Information EngineeringTianjin UniversityTianjin 300072China Continental-NTU Corporate Lab School of Electrical and Electronic EngineeringNanyang Technological UniversitySingapore 639798Singapore

This paper studies the periodic zero-dynamics attacks(ZDAs)in multi-agent systems without velocity measurements under directed ***,two types of attack modes are addressed,i.e.,infinite number and finite number of zero-dynamics *** the former case,the authors show that the consensus of the considered system cannot be *** the latter case,the dynamic evolution of the agents is investigated and it is found that only attacking the rooted agents can destroy the ***,a sufficient condition which quantifies whether or not the consensus value is destroyed is given,revealing the relationship among parameters of system model,filter and attack ***,simulations are carried out to verify the effectiveness of the theoretical findings.

关键词： Consensus directed graph multi-agent systems zero-dynamics attacks

Nonlocal symmetries,soliton-cnoidal wave solution and soliton molecules to a(2+1)-dimensional modified KdV system

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Communications in Theoretical Physics 2024年第4期76卷 14-21页

作者： Jianyong wang Bo ren Department of Mathematics and Physics Quzhou UniversityQuzhou 324000China Department of Mathematics Zhejiang University of TechnologyHangzhou 310014China

A(2+1)-dimensional modified KdV(2DmKdV)system is considered from several ***,residue symmetry,a type of nonlocal symmetry,and the Bäcklund transformation are obtained via the truncated Painlevéexpansion ***,the residue symmetry is localized to a Lie point symmetry of a prolonged system,from which the finite transformation group is ***,the integrability of the 2DmKdV system is examined under the sense of consistent tanh expansion ***,explicit soliton-cnoidal wave solutions are ***,abundant patterns of soliton molecules are presented by imposing the velocity resonance condition on the multiple-soliton solution.

关键词： soliton-cnoidal wave solution nonlocal symmetry soliton molecule (2+1)-dimensional modified KdV system

Towards growth of pure AB-stacked bilayer graphene single crystals

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Nano Research 2024年第5期17卷 4616-4621页

作者： Xiaowen Zhang Tao Zhou Yunlong ren zuo Feng Ruixi Qiao Qinghe wang Bin wang Jinxia Bai Muhong Wu Zhilie Tang Xu Zhou Kaihui Liu Xiaozhi Xu Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum MaterialsSchool of PhysicsSouth China Normal UniversityGuangzhou 510006China Guangdong-Hong Kong Joint Laboratory of Quantum Matter School of PhysicsSouth China Normal UniversityGuangzhou 510006China Physical Science and Engineering Division King Abdullah University of Science and TechnologyThuwal 23955–6900Saudi Arabia State Key Laboratory for Mesoscopic Physics Frontiers Science Center for Nano-optoelectronicsSchool of PhysicsPeking UniversityBeijing 100871China Institute for Frontier Science Nanjing University of Aeronautics and AstronauticsNanjing 210094China International Centre for Quantum Materials Collaborative Innovation Centre of Quantum MatterPeking UniversityBeijing 100871China Songshan Lake Materials Laboratory Institute of PhysicsChinese Academy of SciencesDongguan 523808China

Given its intriguing band structure and unique tunable bandgap,AB-stacked bilayer graphene has great potentials in the applications of high-end electronics,optoelectronics and *** epitaxial growth of AB-stacked single-crystal bilayer graphene films requires a strict AB-stacked lattice,identical orientations and seamless stitching of bilayer graphene ***,the particles inevitably present on the metal surface that produced during high temperature growth would induce random orientations,twisted stacking islands,and uncontrollable multilayers,which is a great challenge to ***,we propose a heat-resisting-box assisted strategy to produce nearly pure AB-stacked bilayer graphene single-crystal films on Cu/Ni(111)*** our technique,the particles on the Cu/Ni(111)surface are effectively eliminated,which greatly minimizes the occurrence of randomly twisted islands and uncontrollable *** as-grown AB-stacked bilayer graphene films show>99%alignment and>99%AB stacking *** work provides a promising method towards the growth of pure AB-stacked bilayer graphene single crystals and would accelerate its device applications.

关键词： bilayer graphene AB stacking uniform growth heat-resisting box

Optimization Control of Multi-Mode Coupling All-Wheel Drive System for Hybrid Vehicle

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Chinese Journal of Mechanical Engineering 2024年第2期37卷 340-355页

作者： Lipeng Zhang Zijian wang Liandong wang Changan ren School of Vehicle and Energy Yanshan UniversityQinhuangdao 066004China

The all-wheel drive(AWD)hybrid system is a research focus on high-performance new energy vehicles that can meet the demands of dynamic performance and passing *** optimization of the power and economy of hybrid vehicles becomes an issue.A unique multi-mode coupling(MMC)AWD hybrid system is presented to realize the distributed and centralized driving of the front and rear axles to achieve vectored distribution and full utilization of the system power between the axles of *** on the parameters of the benchmarking model of a hybrid vehicle,the best model-predictive control-based energy management strategy is ***,the drive system model was built after the analysis of the MMC-AWD’s drive ***,three fundamental strategies were established to address power distribution adjustment and battery SOC maintenance when the SOC changed,which was followed by the design of a road driving force ***,the energy consumption rate in the average time domain was processed before designing the minimum fuel consumption controller based on the equivalent fuel consumption ***,the advantage of the MMC-AWD was confirmed by comparison with the dynamic performance and economy of the BYD Song PLUS *** findings indicate that,in comparison to the comparative hybrid system at road adhesion coefficients of 0.8 and 0.6,the MMC-AWD’s capacity to accelerate increases by 5.26%and 7.92%,*** the road adhesion coefficient is 0.8,0.6,and 0.4,the maximum climbing ability increases by 14.22%,12.88%,and 4.55%,*** a result,the dynamic performance is greatly enhanced,and the fuel savings rate per 100 km of mileage reaches 12.06%,which is also very *** proposed control strategies for the new hybrid AWD vehicle can optimize the power and economy simultaneously.

关键词： Hybrid vehicle All-wheel drive Multi-mode coupling Energy management Model predictive control

Conceptual design and control method for a noncontact annular electromagnetic stabilized satellite platform

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Chinese Journal of Aeronautics 2024年第1期37卷 256-270页

作者： He LIAO Daixin wang Yuan ren Weijie wang Institute of Astronautics Nanjing University of Aeronautics and AstronauticsNanjing 211106China Department of Basic Course Space Engineering UniversityHuairou DistrictBeijing 101416China

Disturbance-Free Payload(DFP)spacecraft can meet the requirements of ultra-high attitude pointing accuracy and stability for future space ***,as the main control actuators of DFP spacecraft,Linear Non-Contact Lorentz Actuators(LNCLAs)have control output problems with six-degree-of-freedom coupling and nonlinear effects,which will affect the attitude control performance of DFP *** solve this problem,a novel concept for Non-Contact Annular Electromagnetic Stabilized Satellite Platform(NCAESSP)is proposed in this *** concept is centered on replacing the LNCLAs with a non-contact annular electromagnetic actuator to solve the two problems mentioned ***,for the different control requirements of the payload module and the support module of the NCAESSP,a high-precision attitude controller based on the robust model matching method and a dual quaternion-based adaptive sliding mode controller are ***,the simulation results verify the feasibility and effectiveness of the proposed approach.

关键词： Disturbance-free payload Robust model matching Dual quaternion Sliding mode control Collision avoidance

Development *** in limited urban sprawl:An integrated framework for resolving the urban boundary dilemma in China

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Journal of Geographical Sciences 2024年第7期34卷 1371-1393页

作者： SONG Xiangxiang ZHANG zuo wang Zhe LIU Yanzhong School of Public Administration Central China Normal UniversityWuhan430079China College of Resource and Environmental Engineering Wuhan University of Science and TechnologyWuhan430081China

The strategic delineation of the urban development boundary(UDB)is an effective initiative for efficient land resource allocation and for facilitating planned urban *** align with sustainable development objectives,UDB definitions have evolved to reconcile urban development with ecological *** study presents a UDB delineation framework from an integrated perspective that incorporates both demand-oriented and comprehensive ***,the urban construction land demand area was estimated based on population projections,meanwhile,the ecological red line(ERL)was delineated and integrated into the evaluation of the construction land ***,with the demand area as the simulation target and unsuitable areas as comprehensive constraints,the UDB was delineated by simulating future land use *** proposed framework was applied to Wuhan,a rapidly urbanizing city in central China,where the delineation of the UDB serves the dual purpose of managing the rapid expansion of built-up land and achieving a harmonious balance between urban development imperatives and ecological protection ***,based on the results and analysis,policy implications for the rational spatial planning of Wuhan were proposed,encompassing the spatial patterns and scientific decision-making in ecological conservation and urban *** results demonstrate that the efficacy of adopting a comprehensive perspective in delineating UDB effectively reconciles the competing needs of urban development and *** framework and the policy insights derived in this study could inform spatial planning efforts not only in Wuhan but also in other cities facing the dilemma of urban development and ecological protection.

关键词： urban development boundary(UDB) ecological red line(ERL) urban land suitability land use simulation integrated framework spatial decision-making

Predicting the evolution of electrochemical trepanning for inner blisks with a chamfer structure at blade tip

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Chinese Journal of Aeronautics 2024年第9期37卷 560-576页

作者： Erhao JIAO Dong ZHU Penghui wang Hang zuo Liyong CHEN College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China

Electrochemical trepanning(ECTr)is an effective electrochemical machining(ECM)technique that can be used to manufacture the integral components of aero-engine *** study focused on the dynamic evolution of ECTr for production of inner blisks(bladed disks)with a special chamfer structure at blade *** to the existence of chamfer,the ECTr process of inner blades is in a non-equilibrium state during the early stages,and the physical field changes in the machining gap are complex,making it difficult to predict the forming *** this paper,a dynamic evolution model(DEM)of inner blade ECTr with a special chamfer at blade tip structure is proposed,and an ECTr multi-physical fields simulation study was carried *** evolution of the chamfer at blade tip was analyzed and data related to chamfer were predicted based on the dependence of anode boundary properties with machining time and feed *** addition,the dis-tributions of current density,electrolyte flow rate,bubble volume fraction,temperature rise,and electrolyte conductivity in the machining area at different times were obtained by combining them with the multi-physical fields simulation ***,a series of ECTr experiments were conducted,in which,as the feed rate increased,the surface quality and machining accuracy of the inner blades were *** with the simulation results,the error in machining accu-racy of the chamfer profile is controlled within±2%,and the machining accuracy of the blade full profile was controlled within±0.2 mm,indicating that the model proposed in this study was effec-tive in predicting the evolution of inner blades ECTr with chamfer structures at blade tip.

关键词： Chamfer structure Inner blisk Electrochemical trepanning(ECTr) Dynamic evolution model Forming prediction Multiphysics Machining quality

Finite-size-induced non-Hermitian phase transitions in real space

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Science China(Physics,Mechanics & Astronomy) 2024年第11期67卷 105-111页

作者： Hongfei wang Biye Xie Wei ren Department of Physics International Center for Quantum and Molecular StructuresShanghai UniversityShanghai 200444China School of Science and Engineering The Chinese University of Hong KongShenzhen 518172China

While non-Hermiticity provokes intriguing phenomena without Hermitian counterparts, e.g., the skin effect and the breakdown of bulk-boundary correspondence, attracting extensive attention both in fundamental physics and device engineering, the role of finite sizes therein remains elusive. Here, we propose a class of finite-size-induced non-Hermitian phase transitions, relying upon higher-order topological invariants associated with real-space wave functions. The phase diagrams for general non-Hermitian chiral models are further acquired to demonstrate our topological definition. Such phase transitions are elucidated qualitatively by an effective intercell coupling alteration that depends on finite sizes in respective directions. Besides, we mimic these phenomena by analogizing the circuit Laplacian in finite-size electric circuits with nonreciprocal couplings. The resultant admittance spectra agree with our theoretical predictions. Our findings shed light on the finite-size mechanism of non-Hermitian topological phase transitions and pave the way for applications in switching and sensing.

关键词： non-Hermitian phase transitions finite-size effects higher-order topological invariants