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Centralized isolation of Helicobacter pylori from multiple centers and transport condition influences

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World Journal of Gastroenterology 2015年第3期21卷 944-952页

作者： Ya-Nan Gong You-Ming Li Ning-Min Yang Hong-Zhang Li Feng Guo Lang Lin Qun-Ying Wang jia-Kun Zhang zi-zhong ji ji-Bo Mao Jun-Liang Mao Zheng-Chao Shi Wu-Heng Tang Xin-jian Zhu Wei Shao Xiao-Feng Zhang Xing-Hua Wang Yue-Feng Tong Mi-Zu jiang Guang-Lan Chen Zhi-Yong Wang Hui-Min Tu Guo-Fa jiang jian-Sheng Wu Xu-Peng Chen Qiu-Long Ding Hong Ouyang Feng-Zhe jin Yan-Li Xu jian-zhong Zhang State Key Laboratory for Infectious Disease Prevention and Control National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and Prevention Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases The First Affiliated Hospital College of MedicineZhejiang University Zhiyuan Medical Inspection Institute Co. Ltd. Sanmen People’s Hospital The First People’s Hospital of Xiaoshan District The First People’s Hospital of Cangnan jinhua Municipal Central Hospital The First People’s Hospital of Pingyang The First Hospital of jiaxing Zhoushan Hospital The First People’s Hospital of Wenling Rui’an People’s Hospital Maternal and Child Health Hospital of Zhoushan City Shangyu People’s Hospital People’s Hospital of Putuo District Zhoushan Hangzhou First People’s Hospital Qingtian People’s Hospital The First People’s Hospital of Yongkang The Children’s Hospital Zhejiang University School of Medicine Lishui People’s Hospital The Affiliated Hospital of Hangzhou Normal University Wuxi No.4 Hospital Affiliated to Suzhou University jinhua Wenrong Hospital The First Affiliated Hospital of Wenzhou Medical College Yueqing People’s Hospital Tiantai People’s Hospital Lin’an people’s Hospital Rui’an City TCM Hospital Medical College of Hebei University of Engineering

AIM:To evaluate the efficacy of centralized culture and possible influencing ***:From January 2010 to July 2012,66452 patients with suspected Helicobacter pylori(***) infection from 26 hospitals in Zhejiang and jiangsu Provinces in China underwent gastrointestinal *** mucosal biopsies were taken from the antrum for *** biopsies were transported under natural environmental temperature to the central laboratory in Hangzhou city and divided into three groups based on their transport time:5,24 and 48 *** culture results were reported after 72 h and the positive culture rates were analyzed by a χ2 *** additional 5736 biopsies from ***-positive patients(5646 rapid urease test-positive and 90 14C-urease breath test-positive) were also cultured for quality control in the central laboratory ***:The positive culture rate was 31.66%(21036/66452) for the patient samples and 71.72%(4114/5736) for the ***-positive quality control *** the 5 h transport group,the positiveculture rate was 30.99%(3865/12471),and 32.84%(14960/45553) in the 24 h transport *** contrast,the positive culture rate declined significantly in the 48 h transport group(26.25%; P < 0.001).During transportation,the average natural temperature increased from 4.67 to 29.14℃,while the positive culture rate declined from 36.67%(1462/3987) to 24.12%(1799/7459).When the temperature exceeded 24℃,the positive culture rate decreased significantly,especially in the 48 h transport group(23.17%).CONCLUSION:Transportation of specimens within 24 h and below 24℃ is reasonable and acceptable for centralized culture of multicenter *** samples.

关键词： Centralized isolation Helicobacter pylori Influenc

High‑Entropy Electrode Materials:Synthesis,Properties and Outlook

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Nano-Micro Letters 2025年第1期17卷 472-506页

作者： Dongxiao Li Chang Liu Shusheng Tao jieming Cai Biao zhong jie Li Wentao Deng Hongshuai Hou Guoqiang Zou Xiaobo ji College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083People’s Republic of China School of Chemistry and Chemical Engineering Hunan Institute of EngineeringXiangtan 411104People’s Republic of China

High-entropy materials represent a new category of high-performance materials,first proposed in 2004 and extensively investigated by researchers over the past two *** definition of high-entropy materials has continuously *** the last ten years,the discovery of an increasing number of high-entropy materials has led to significant advancements in their utilization in energy storage,electrocatalysis,and related domains,accompanied by a rise in techniques for fabricating high-entropy electrode ***,the research emphasis has shifted from solely improving the performance of high-entropy materials toward exploring their reaction mechanisms and adopting cleaner preparation ***,the current definition of high-entropy materials remains relatively vague,and the preparation method of high-entropy materials is based on the preparation method of single metal/low-or medium-entropy *** should be noted that not all methods applicable to single metal/low-or medium-entropy materials can be directly applied to high-entropy *** this review,the definition and development of high-entropy materials are briefly ***,the classification of high-entropy electrode materials is presented,followed by a discussion of their applications in energy storage and catalysis from the perspective of synthesis ***,an evaluation of the advantages and disadvantages of various synthesis methods in the production process of different high-entropy materials is provided,along with a proposal for potential future development directions for high-entropy materials.

关键词： High-entropy Energy storage Electrode materials

内镜介入联合生长抑素对重症急性胰腺炎患者临床症状及相关生化指标的影响

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世界华人消化杂志 2018年第2期26卷 131-136页

作者：陈一鹏冀子中韩丰蔡陈效嘉兴市第一医院消化内科浙江省嘉兴市314000

目的探讨内镜介入联合生长抑素对重症急性胰腺炎(severe acute pancreatiti,SAP)患者临床症状及相关生化指标的影响.方法选择2015-01/2016-06嘉兴市第一医院收治的SAP患者148例为研究对象,采用随机数字表法分为观察组和对照组各74例.所... 详细信息

目的探讨内镜介入联合生长抑素对重症急性胰腺炎(severe acute pancreatiti,SAP)患者临床症状及相关生化指标的影响.方法选择2015-01/2016-06嘉兴市第一医院收治的SAP患者148例为研究对象,采用随机数字表法分为观察组和对照组各74例.所有患者均给予抗炎等常规对症治疗,对照组给予生长抑素微泵静脉输注,观察组内镜介入联合生长抑素动脉灌注治疗方法.比较两组临床症状缓解时间、血清炎性因子、胃肠激素、并发症等.结果观察组腹痛、高热、恶心呕吐、腹膜刺激征缓解时间明显短于对照组(t=10.720、8.226、11.840、9.143,P<0.05,P<0.01);血清白介素-8、高敏C反应蛋白、肿瘤坏死因子-α含量明显低于对照组(t=17.509、20.189、14.847,P<0.01);血清血管活性肽、胃泌素含量明显低于对照组,胃动素含量明显高于对照组(t=14.586、11.374、7.126,P<0.05,P<0.05,P<0.01);胰腺及周围组织坏死、胰腺肠瘘、胰腺脓肿、胰腺假性囊肿等发生率明显低于对照组(χ~2=7.306、7.955、8.976、5.049,P<0.05,P<0.01).结论内镜介入联合生长抑素有助于缓解SAP患者炎症反应,调节胃肠功能,进而改善患者临床症状,减少并发症的发生率.

关键词：重症急性胰腺炎内镜介入生长抑素炎性因子胃肠激素

集成深度强化学习在股票指数投资组合优化中的应用分析

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计算机科学与探索 2025年第1期19卷 237-244页

作者：冀中张文嘉天津大学电气自动化与信息工程学院天津300072 天津大学佐治亚理工深圳学院天津300072

基于集成深度强化学习的投资组合选择是当前量化金融领域的关键技术之一。然而,目前采用上一窗口阶段最优指标决定下一阶段代理的集成滚动窗口方法存在一定的滞后性。为了有效应对这一不足,提出了双层嵌套集成深度强化学习方法。该方法... 详细信息

基于集成深度强化学习的投资组合选择是当前量化金融领域的关键技术之一。然而,目前采用上一窗口阶段最优指标决定下一阶段代理的集成滚动窗口方法存在一定的滞后性。为了有效应对这一不足,提出了双层嵌套集成深度强化学习方法。该方法对三种代理(优势演员-评论员、深度确定性策略梯度和近端策略优化)进行两层嵌套模式,第一层集成通过最优化夏普比率进行阶段模型选择,第二层通过加权投票的方法集成三种深度强化学习算法,从单次训练中收集多个模型快照,在训练期间利用这些模型进行集成预测。分别对上证50投资指数和道琼斯指数及其包含的股票进行了投资组合研究,将持有指数被动策略和均值方差投资组合策略作为基线策略。实验采用了投资组合价值、年化回报率、年化波动率、最大回撤和夏普比率等指标作为对比指标。结果表明,所提出的集成方法在实用性和有效性上表现出较好的性能。

关键词：股票投资组合交易策略深度强化学习双层嵌套集成深度强化学习方法集成学习

面向可持续雨洪管理的低影响开发措施综合效益评估

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天津理工大学学报 2025年第1期41卷 126-133页

作者：訾妍钟炜天津理工大学管理学院

为满足低影响开发(low impact development, LID)组合在城市雨洪管理过程中良好的应用效果和经济效益，应用暴雨洪水管理模型(stormwater management model, SWMM)结果指标和项目全生命周期成本理论，构建不同LID组合方案下的环境-成本... 详细信息

为满足低影响开发(low impact development, LID)组合在城市雨洪管理过程中良好的应用效果和经济效益，应用暴雨洪水管理模型(stormwater management model, SWMM)结果指标和项目全生命周期成本理论，构建不同LID组合方案下的环境-成本效益综合评价系统，并通过数值模拟和数理分析相结合的方法评估各备选方案的综合效益。为验证理论模型的可行性，将9种不同布设比例的LID组合分别嵌入实际项目中进行模拟和评估。结果表明，综合效益最高的LID组合为“45%的绿色屋顶+15%的植草沟+30%的雨水花园+70%的透水铺装”,其径流总量削减率为52.83%、4类污染负荷削减率均为80%以上且每年消耗的总成本费用为22 416 350元。该评价体系为优化城市可持续雨洪管理提供新思路，同时为建设开发海绵城市提供方案指导。

关键词：低影响开发综合效益评估暴雨洪水管理模型可持续雨洪管理海绵城市

Menstrual and Reproductive Characteristics of Patients with Primary Sjogren’s Syndrome:A 7-year Single-center Retrospective Study

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Current Medical Science 2023年第1期43卷 139-145页

作者： Ying-zi ZHU ji-xin zhong Ling-li DONG Department of Rheumatology and Immunology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Objective Primary Sjogren’s syndrome(pSS)is a systemic autoimmune disease that mainly affects the exocrine gland,especially in ***,the results of studies on the menstruation or fertility of pSS patients remain *** study aimed to examine the menstrual and reproductive characteristics of pSS *** Clinical data of 449 pSS patients who were admitted to Tongji Hospital in Hubei,China,from January 2015 to November 2021 were obtained and their menstrual and reproductive information *** addition,the clinical features of pSS patients with premenopausal or postmenopausal onset were *** The spontaneous abortion rate of pSS patients was not higher than the reported rate of the general population and that the age of menarche,menstrual cycle,and menstrual period of pSS patients did not significantly differ from those reported in the general population;however,early menopause seemed to be more common in pSS *** involvement(27.96%vs.15.00%,P=0.005)and hyperglobulinemia(10.64%vs.4.16%,P=0.033)were more common in patients with premenopausal pSS onset,but patients with postmenopausal onset had a significantly greater incidence of interstitial lung disease(32.50%vs.17.02%,P=0.0004).Also,erythropenia(47.00%vs.31.25%,P=0.002),hypoalbuminemia(19.49%vs.8.22%,P=0.0009),and prevalence of high hypersensitive C-reactive protein levels(21.67%vs.10.94%,P=0.005)were more common in pSS patients with postmenopausal ***,the rate of abnormal pregnancy was significantly greater in patients with premenopausal onset(9.72%vs.2.50%,P=0.011).Conclusion Patients with pSS onset before or after menopause may have different risks in pulmonary involvement and laboratory manifestations.

关键词： primary Sjogren's syndrome menstruation fertility clinical features

Study on the prediction and inverse prediction of detonation properties based on deep learning

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Defence Technology（防务技术） 2023年第6期24卷 18-30页

作者： zi-hang Yang ji-li Rong zi-tong Zhao Department of Mechanics School of Aerospace EngineeringBeijing Institute of TechnologyBeijing100081China

The accurate and efficient prediction of explosive detonation properties has important engineering significance for weapon *** methods for predicting detonation performance include empirical formulas,equations of state,and quantum chemical calculation *** recent years,with the development of computer performance and deep learning methods,researchers have begun to apply deep learning methods to the prediction of explosive detonation *** deep learning method has the advantage of simple and rapid prediction of explosive detonation ***,some problems remain in the study of detonation properties based on deep *** example,there are few studies on the prediction of mixed explosives,on the prediction of the parameters of the equation of state of explosives,and on the application of explosive properties to predict the formulation of *** on an artificial neural network model and a one-dimensional convolutional neural network model,three improved deep learning models were established in this work with the aim of solving these *** training data for these models,called the detonation parameters prediction model,JWL equation of state(EOS)prediction model,and inverse prediction model,was obtained through the KHT thermochemical *** training,the model was tested for overfitting using the validation-set *** the model-accuracy test,the prediction accuracy of the model for real explosive formulations was tested by comparing the predicted value with the reference *** results show that the model errors were within 10%and 3%for the prediction of detonation pressure and detonation velocity,*** accuracy refers to the prediction of tested explosive formulations which consist of TNT,RDX and *** the prediction of the equation of state for explosives,the correlation coefficient between the prediction and the reference curves was above *** the prediction of the inverse predi

关键词： Deep learning Detonation properties KHT thermochemical Code JWL equation of states Artificial neural network One-dimensional convolutional neural network

Carbon shell coated hollow NiCoSe_(x)composite as high-performance anode for lithium storage

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Rare Metals 2021年第11期40卷 3185-3194页

作者： zi-zhong Chen jia-Gang Hou ji Zhou Peng Huang Hai-Qing Wang Cai-Xia Xu Institute for Advanced Interdisciplinary Research(iAIR) University of JinanJinan 250022China Shandong Collaborative Innovation Center of Technology and Equipements for Biological Diagnosis and Therapy Jinan 250022China Qilu University of Technology(Shandong Academy of Sciences) Jinan 250353China

Hollow NiCoSe_(x)(H-NiCoSe_(x)) nanospheres encapsulated with carbon shell were prepared via one-step easy solvothermal method followed by the carbon coating process.H-NiCoSe_(x)@C has large interior void with the uniform dimension around 350 nm and the thickness of carbon shell around 20-30 *** with the large interior void as well as robust protective carbon shell,H-NiCoSe_(x)@C can retain the reversible capacity of 805.6 mAh·g^(-1) after 100 cycles at 200 mA·g^(-1).In particular,H-NiCoSe_(x)@C delivers large reversible capacity of 1532.2 mAh·g^(-1) upon cycling for 1000 loops at 1000 mA·g^(-1)with the capacity retention as high as 128.2% upon long period of *** at the high rate of 3000 mA·g^(-1),its specific capacity still retains up to 659.3 mAh·g^(-1).The superior lithium storage performances for H-NiCoSe_(x)@C profit from its robust hollow core-shell structure as well as enhanced electrical conductivity and ion transport.

关键词： Selenide Hollow sphere Carbon shell Lithium-ion batteries Anode

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服务器无感知计算系统性能优化技术研究综述

软件学报 2025年第1期36卷 47-78页

作者：杨光刘杰曲慕子王帅叶丹钟华中国科学院大学中国科学院软件研究所软件工程技术研究开发中心计算机科学国家重点实验室(中国科学院软件研究所)

服务器无感知计算是新兴的云计算模式,它基于“函数即服务(FaaS)”的范式,以函数为部署和调度的基本单位,为用户提供大规模并行和自动伸缩的函数执行服务,且无需用户管理底层资源.对于用户,服务器无感知计算能够帮助他们摆脱集群底层基... 详细信息

服务器无感知计算是新兴的云计算模式,它基于“函数即服务(FaaS)”的范式,以函数为部署和调度的基本单位,为用户提供大规模并行和自动伸缩的函数执行服务,且无需用户管理底层资源.对于用户,服务器无感知计算能够帮助他们摆脱集群底层基础设施管理的负担,专注于业务层的开发和创新;对于服务提供商,服务器无感知计算将应用分解为细粒度的函数,极大地提高了调度效率和资源利用率.显著的优势让服务器无感知计算迅速吸引了业界的注意,然而,服务器无感知计算与传统云计算迥然不同的计算模式以及对任务各方面的严格限制给应用的迁移带来了诸多障碍,各种越来越复杂的任务也对服务器无感知计算的性能提出了越来越高的要求,服务器无感知计算的性能优化成为一个重要的研究课题.从4个方面对服务器无感知计算系统性能优化技术的相关研究工作进行梳理和综述,并介绍现有的系统实现.(1)介绍面向典型任务的优化技术,包括任务适配和针对特定任务的系统优化;(2)综述沙箱环境的优化工作,包括沙箱方案和冷启动优化技术,它们是决定函数运行速度的核心;(3)概括I/O和通信技术的优化,它们是服务器无感知计算应用程序的主要性能瓶颈;(4)简述相关的资源调度技术,包括面向平台和面向用户的调度策略,它们决定着系统的资源利用率和任务的执行效率.最后,总结当前服务器无感知计算性能优化技术所面临的问题和挑战,并展望未来可能的发展方向.

关键词：服务器无感知计算函数即服务云函数云计算性能优化