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The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li Luo Yong-Heng Zhao Gang Zhao Li-Cai Deng Xiao-Wei Liu Yi-Peng Jing Gang Wang Hao-Tong Zhang Jian-Rong Shi Xiang-Qun Cui Yao-Quan Chu Guo-Ping Li Zhong-Rui Bai Yue Wu Yan Cai Shu-Yun Cao Zi-huang Cao Jeffrey L.Carlin Hai-Yuan Chen Jian-Jun Chen Kun-Xin Chen Li Chen Xue-Lei Chen Xiao-Yan Chen Ying Chen Norbert Christlieb Jia-Ru Chu Chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-Wei Fan Lei Feng Jian-Ning Fu Peng Gao Xue-Fei Gong Bo-Zhong Gu Yan-Xin Guo Zhan-Wen Han Bo-Liang He Jin-Liang Hou Yong-hui Hou Wen Hou Hong-zhuan hu Ning-Sheng hu Zhong-Wen hu Zhi-Ying huo Lei Jia Fang-hua Jiang Xiang Jiang Zhi-Bo Jiang Ge Jin Xiao Kong Xu Kong Ya-Juan Lei Ai-hua Li Chang-hua Li Guang-Wei Li Hai-Ning Li Jian Li Qi Li Shuang Li Sha-Sha Li Xin-Nan Li Yan Li Yin-Bi Li Ye-Ping Li Yuan Liang Chien-Cheng Lin Chao Liu Gen-Rong Liu Guan-Qun Liu Zhi-Gang Liu Wen-Zhi Lu Yu Luo Yin-Dun Mao Heidi Newberg Ji-Jun Ni Zhao-Xiang Qi Yong-Jun Qi Shi-Yin Shen huo-Ming Shi Jing Song Yi-Han Song Ding-Qiang Su Hong-Jun Su Zheng-Hong Tang Qing-Sheng Tao Yuan Tian Dan Wang Da-Qi Wang Feng-Fei Wang Guo-Min Wang Hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-Ling Wang Jian-Ping Wang Jun-Xian Wang Lei Wang Meng-Xin Wang Shou-Guan Wang Shu-Qing Wang Xia Wang Ya-Nan Wang You Wang Yue-Fei Wang You-Fen Wang Peng Wei Ming-Zhi Wei Hong Wu Ke-Fei Wu Xue-Bing Wu Yu-Zhong Wu Xiao-Zheng Xing Ling-Zhe Xu Xin-Qi Xu Yan Xu Tai-Sheng Yan De-hua Yang Hai-Feng Yang hui-Qin Yang Ming Yang Zheng-Qiu Yao Yong Yu hui Yuan Hai-Bo Yuan Hai-Long Yuan Wei-Min Yuan Chao Zhai En-Peng Zhang hua-Wei Zhang Jian-Nan Zhang Li-Pin Zhang Wei Zhang Yong Zhang Yan-Xia Zhang Zheng-Chao Zhang Ming Zhao Fang Zhou Xu Zhou Jie Zhu Yong-Tian Zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

Reversible Release and Fixation of Bromine in Vacancy-Ordered Bromide Perovskites

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Energy & Environmental Materials 2020年第4期3卷 535-540页

作者： Yang-Peng Lin Bing Xia Sanlue hu Yu Zhong Yue-E huang Zhi-zhuan Zhang Ni Wu Yong-Wei Wu Xiao-hui Wu Xiao-Ying huang Zewen Xiao Ke-Zhao Du College of Chemistry and Materials Science Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical EngomineeringFujian Normal UniversityFuzhou 350007China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China

Bromine is an irreplaceable reagent for many important applications including necessary additive for flame retardants and rubber ***,the toxicity,causticity,and vaporability of bromine make the safe usage and transportation of bromine challenging,which can be alleviated by the bromine ***,vacancy-ordered bromide perovskites such as Cs^(4)Sb_(2)Br_(12)and Cs_(2)PdBr_(6)are selected out for the bromine fixation through density-functional theory calculations and *** redox within the bromide perovskites is designed to provide the driving force for the reversible release and fixation of *** and cooling the title bromide perovskites in a necked ampoule make the bromine visible and separable from the solid *** composition engineering(i.e.,Cs_(4)Sb_(2)Br_(12)vs Rb_(4)Sb_(2)Br_(12),and Cs_(4)Sb_(2)Br_(12)vs Cs_(2)PdBr_(6))can effectively tune the stability(against water and high temperature)and the bromine storage capacity(from9.30%to 18.76%).In addition,this work can provide a one-step preparation method for the liquid bromine without further purification.

关键词： bromine fixation-release halide perovskite redox

Overexpression of MiR-633 Suppresses the Tumorigenicity of Gastric Cancer Cells and Induces Apoptosis by Targeting MAPK1

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Current Medical Science 2022年第5期42卷 1033-1045页

作者： Hai-long LI Yao-hui SONG Zheng-ping DU Yong-hua hu zhuan-xiong WANG Xi CHEN Xing-mei LU Ying-xia CHEN Yong-qiang DUAN Xiang-dong Zhu Department of Geriatrics Affiliated Hospital of Gansu University of Traditional Chinese MedicineLanzhou730000China Department of Internal Medicine The First Clinical Medical CollegeGansu University of Chinese MedicineLanzhou730000China Provincial-Level Key Laboratory for Molecular Medicine of Major Diseases and The Prevention and Treatment with Traditional Chinese Medicine in Gansu Colleges and Universities Gansu University of Chinese MedicineLanzhou730000China School of Basic Medicine Gansu Vocational College of HealthLanzhou730300China College of Traditional Chinese Medicine Ningxia Medical UniversityYinchuan750004China

Objective MicroRNA(miRNA/miR)-633 is dysregulated in several types of cancers and is involved in ***,the function and role of this miRNA in gastric cancer(GC)are not fully *** aim of the present study was to evaluate miR-633 expression in GC cell lines and in GC tissue *** normal tissue,and to determine its association with clinicopathological *** work was extended to investigate the effects of miR-633 overexpression on tumor cells in *** Reverse transcription-quantitative PCR(RT-qPCR)was used to detect and compare the expression level of miR-633 in GC cells,as well as in GC and normal adjacent tissue *** clinical significance of miR-633 was also ***-633 lentivirus(LV-miR-633)and negative control lentivirus(LV-NC)were generated and used to transduce SGC-7901 and HGC-27 GC cells in order to analyze the effect of miR-633 on their *** effects of miR-633 overexpression on GC cell proliferation,apoptosis,migration and invasion were *** target gene of miR-633 was predicted,then confirmed using a dual luciferase reporter gene assay,RT-qPCR and Western *** MiR-633 was significantly downregulated in GC cell lines,as well as in GC tissue compared with adjacent normal ***,miR-633 expression was associated with the tumor/node/metastasis(TNM)stage,invasion depth,Borrmann classification and lymph node metastasis(P<0.05).Compared with the LV-NC group,transduction with LV-miR-633 reduced the proliferation,the number of clones,the wound healing rate,the number of invading cells and the number of cells in the G1 phase of the cell cycle(P<0.01).LV-miR-633 also increased the apoptosis rate(P<0.01).The expression level of mitogen-activated protein kinase(MAPK)1,high-mobility group box 3(HMGB3),claudin 1(CLDN1)and MAPK13 were downregulated in LV-miR-633-transduced cells(P<0.01).The dual luciferase reporter assay confirmed that the 3′-untranslated region of MAPK1 was the t

关键词： miR-633 gastric cancer apoptosis metastasis mitogen-activated protein kinase 1

基于特征图谱、化学计量学和多指标成分测定的不同商品规格葛花质量差异分析

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药物分析杂志 2024年第5期44卷 903-911页

作者：张立军李鹏李隆海张新玥马冬妮张转平胡芳弟王磊柯红梅李鹏刘丽吴春燕李小安兰州大学药学院兰州730000 陕西省安康市食品药品检验检测中心安康725000 商洛市药品检验所商洛726000 旬阳市金寨镇农业综合服务站旬阳725751 北京中医药大学中药学院北京1000294 甘肃省敦煌市医院敦煌736200 安康市天源植物提取有限公司安康725000

目的:建立能有效区分葛花(Pueraria lobata(Willd.)Ohwi)、粉葛花(Pueraria thomsonii Benth.)及其混淆品种的特征图谱和多指标成分测定分析方法,用于葛花药材的整体质量控制。方法:采用高效液相色谱法(HPLC)对不同商品规格葛花中主要... 详细信息

目的:建立能有效区分葛花(Pueraria lobata(Willd.)Ohwi)、粉葛花(Pueraria thomsonii Benth.)及其混淆品种的特征图谱和多指标成分测定分析方法,用于葛花药材的整体质量控制。方法:采用高效液相色谱法(HPLC)对不同商品规格葛花中主要化学成分进行分析,确定最佳色谱条件,建立特征图谱;利用主成分分析(PCA)和偏最小二乘判别分析(PLS-DA)对不同商品规格葛花特征图谱数据进行分析,筛选确认差异性标志物;通过与对照品比对,对差异性标志物进行指认,进行定量分析,并分析测定结果。结果:建立了葛花、粉葛花、葛麻姆花及紫藤花的特征图谱,分别匹配了18、27、18及8个共有峰,指认出葛根素(Pu)、大豆苷(Da)、大豆苷元(Dae)、染料木苷(Ge)、染料木素(Gee)、葛花苷(Ka)、glycitin(Gl)、tectoridin(Td)、tectorigenin(Tg)及tectorigenin-7-O-xylosylglucoside(Tx)10个色谱峰,并同时建立了上述10个成分的含量测定方法。PCA和PLS-DA结果可将4种不同商品规格葛花样品明显区分,以Gl、Tx、Ge、Td、Ka及未知化合物(6号峰)为差异性标志物。葛花、粉葛花所含成分明显区别其混淆品,葛花中Ka含量为粉葛花的10倍,Ge含量为粉葛花的50%,未检测到Da、Gl。结论:所建立的特征图谱结合化学计量学及多指标成分测定分析方法简便、可行,可客观、有效地用于葛花药材质量控制,作为修改葛花质量标准提供参考。

关键词：葛花粉葛花混淆品特征图谱化学计量学质量控制差异性标志物葛花苷染料木苷

Mechanistic understanding of the charge storage processes in FeF_(2) aggregates assembled with cylindrical nanoparticles as a cathode material for lithium-ion batteries by in situ magnetometry

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Carbon Energy 2022年第6期4卷 1011-1020页

作者： Zhengqiang hu Fengling Zhang huanyu Liang Hao Zhang huaizhi Wang Tiansheng Wang Renbin Liu Jie Liu Yadong Li Xiaotong Dong Lianyu Bao zhuan Liang Yaqun Wang Shishen Yan Qiang Li Hongsen Li Center for Marine Observation and Communications College of PhysicsQingdao UniversityQingdaoShandongChina College of Electrical Engineering and Automation Shandong University of Science and TechnologyQingdaoShandongChina State Key Laboratory of Crystal Materials School of PhysicsShandong UniversityJinanShandongChina

Transition metal fluorides(TMFs)cathode materials have shown extraordinary promises for electrochemical energy storage,but the understanding of their electrochemical reaction mechanisms is still a matter of debate due to the complicated and continuous changing in the battery internal ***,we design a novel iron fluoride(FeF_(2))aggregate assembled with cylindrical nanoparticles as cathode material to build FeF_(2) lithium-ion batteries(LIBs)and employ advanced in situ magnetometry to detect their intrinsic electronic structure during cycling in real *** results show that FeF_(2) cannot be involved in complete conversion reactions when the FeF_(2) LIBs operate between the conventional voltage range of 1.0–4.0 V,and that the corresponding conversion ratio of FeF_(2) can be further ***,we first demonstrate that the spin-polarized surface capacitance exists in the FeF_(2) cathode by monitoring the magnetic responses over various voltage *** research presents an original and insightful method to examine the conversion mechanism of TMFs and significantly provides an important reference for the future artificial design of energy systems based on spinpolarized surface capacitance.

关键词： charge storage mechanism FeF_(2)cathode materials in situ magnetometry lithium-ion batteries

Transforming growth factor-β1 in invasion and metastasis in colorectal cancer

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World Journal of Gastroenterology 2002年第4期8卷 674-678页

作者： Bin Xiong Hong-Yin Yuan Ming-Bo hu Feng Zhang Zheng-zhuan Wei Ling-Ling Gong Guo-Liang Yang Department of Oncology,Affiliated Zhongnan Hospital of Wuhan University,Wuhan 430071,hubei Province,China Bin Xiong Hong-Yin Yuan Ming-Bo Hu Feng Zhang Zheng-Zhuan Wei Ling-Ling Gong Guo-Liang Yang Department of Oncology Affiliated Zhongnan Hospital of Wuhan University Wuhan 430071 Hubei Province China

AIM：To investigate the role of TGFβ1 in invasion and metastasis in colorectal cancer by analysing TGFβ1 correlated wity depth of tumor invasion,stage and ***:Serum TGFβ1levels were determined in50patients with colorectal cancer and 30healthy volunteers using a TGFβ1 enzyme-linked immunosorbent ***β1 expression in primary and lymph node metastatic lesions were detected in 98cases of colorectal cancer by immunohistochemical staining and in situ ***:Serum levels of TGFβ1 in patients with colorectal cancer(40±18μg·L^-1)were significantly higher than those in the healthy control group(19±8μg·L^-1),P<*** levels of serum TGFβ1were found in 60%of patients with colorectal cancer when the mean+2s was used as the upper limit of the normal range(35.1μg·L^-1).Increases in serum TGFβ1 levels were significantly asociated with Dukei's stage(P<0.05),but there was no significant difference between,Duki's stage Bpatients and Dukei's stage *** the cytoplasm of cancer cells,TGFβ1 was immunostained in37.8%(37/98)of colorectal cancer,and this expression was confirmed by in situ hybridization,Among35cases of colorectal cancer with lymph node metastatic lesions,TGFβ1 positive staining was found in18(51.4%)cases of primary tumor,and 25(71.4%)cases with lymph node metastatic lesions,respectively,Of17cases with no staining in the primary lesion.7(41.2%)casesshowed TGFβ1 staining in the metastatic *** TGFβ1 levels and TGFβ1 expression in colorectal cancer tissues were correlated significantly with depth of tumor invasion,stage and metastasis,Patients in stage C-D,T3-T4and with metastasis had significantly higher TGFβ1 levels than patients in stage A-B,T1-T2and without metastasis(P<0.05).CONCLUSION:These results suggest that transforming growth factor-β1 is closely related to the invasion and metastasis of colorectal *** increased the invasive and metastatic potential of tumor by altering a tumor ***β1 ma

关键词：结直肠癌转化生长因子β1 肿瘤侵袭肿瘤转移作用机制

p85S6K sustains synaptic GluA1 to ameliorate cognitive deficits in Alzheimer’s disease

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Translational Neurodegeneration 2023年第1期12卷 890-907页

作者： Jia-Bing Li Xiao-Yu hu Mu-Wen Chen Cai-Hong Xiong Na Zhao Yan-hui Ge Hao Wang Xiao-Ling Gao Nan-Jie Xu Lan-Xue Zhao Zhi-hua Yu Hong-zhuan Chen Yu Qiu Department of Pharmacology and Chemical Biology Shanghai Jiao Tong University School of MedicineShanghai 200025China Institute of Interdisciplinary Integrative Biomedical Research Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghai 201210China Collaborative Innovation Center for Brain Science Department of Anatomy and PhysiologyShanghai Jiao Tong University School of MedicineShanghai 200025China

Background Ribosomal protein S6 kinase 1(S6K1)is a serine-threonine kinase that has two main isoforms:p70S6K(70-kDa isoform)and p85S6K(85-kDa isoform).p70S6K,with its upstream mammalian target of rapamycin(mTOR),has been shown to be involved in learning and memory and participate in the pathophysiology of Alzheimer’s dis-ease(AD).However,the function of p85S6K has long been neglected due to its high similarity to *** role of p85S6K in learning and memory is still largely *** We fractionated the postsynaptic densities to illustrate the differential distribution of p85S6K and *** was performed to unveil interactions between p85S6K and the GluA1 subunit of AMPA *** roles of p85S6K in synaptic targeting of GluA1 and learning and memory were evaluated by specific knockdown or overexpression of p85S6K followed by a broad range of methodologies including immunofluorescence,Western blot,in situ proximity ligation assay,morphological staining and behavioral ***,the expression level of p85S6K was measured in brains from AD patients and AD model *** p85S6K,but not p70S6K,was enriched in the postsynaptic ***,knockdown of p85S6K resulted in defective spatial and recognition *** addition,p85S6K could interact with the GluA1 subunit of AMPA receptor through synapse-associated protein 97 and A-kinase anchoring protein 79/*** studies demonstrated that p85S6K could directly phosphorylate GluA1 at Ser845 and increase the amount of GluA1 in syn-apses,thus sustaining synaptic function and spine ***,p85S6K was found to be specifically decreased in the synaptosomal compartment in the brains of AD patients and AD *** of p85S6K ameliorated the synaptic deficits and cognitive impairment in transgenic AD model *** These results strongly imply a significant role for p85S6K in maintaining synaptic and cognitive function by interacting with Gl

关键词： Alzheimer’s disease Cognition GluA1 subunit of AMPA receptors Ribosomal S6 protein kinase 1 85 kDa isoform

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钢琴琴弦在弦枕处的断裂性质研究

机械强度 2016年第3期38卷 653-656页

作者：胡倩如颛昕西安音乐学院现代音乐学院西安710061 西安交通大学航天航空学院西安710049

钢琴琴弦在弦枕处最容易断裂,研究琴弦在此处的断裂性质对琴弦的设计及调律具有重要的意义。首先对琴弦的张挂形式以及工作时的受力和振动方式进行了宏观分析。然后在收集到的百组琴弦中选取三组相同键号、相同型号并且已知使用寿命的... 详细信息

钢琴琴弦在弦枕处最容易断裂,研究琴弦在此处的断裂性质对琴弦的设计及调律具有重要的意义。首先对琴弦的张挂形式以及工作时的受力和振动方式进行了宏观分析。然后在收集到的百组琴弦中选取三组相同键号、相同型号并且已知使用寿命的琴弦的断口为研究对象,利用扫描电子显微镜(SEM)对断口形貌进行分析。结果表明,琴弦和弦枕的相互摩擦造成琴弦表面磨损,使得受损区域应力集中。在交变弯曲载荷的作用下,疲劳裂纹萌生并沿截面向深处发展。当裂纹扩展到超过琴弦的断裂强度时发生了韧性断裂,SEM下可观察到断口呈明显的纤维状。

关键词：钢琴琴弦弦枕磨损疲劳断裂

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一种鲁棒的HLLC格式及其稳定性分析

计算力学学报 2020年第6期37卷 685-693页

作者：胡立军袁海专衡阳师范学院数学与统计学院衡阳421002 湘潭大学数学与计算科学学院湘潭411105

精确捕捉接触波和剪切波的Godunov型数值方法,如流行的HLLC格式,在模拟高超声速流动问题时会出现激波异常现象。对HLLC格式进行稳定性分析发现,流体主流方向的扰动都能有效衰减,但是横向的密度与剪切速度的扰动不会衰减。具有特殊对称... 详细信息

精确捕捉接触波和剪切波的Godunov型数值方法,如流行的HLLC格式,在模拟高超声速流动问题时会出现激波异常现象。对HLLC格式进行稳定性分析发现,流体主流方向的扰动都能有效衰减,但是横向的密度与剪切速度的扰动不会衰减。具有特殊对称性的二维Sedov爆轰波问题证明了横向通量和不稳定现象之间的密切联系。利用压力比和马赫数来探测数值激波层亚声速区的横向网格界面,并且在该界面的数值通量上增加熵波粘性和剪切波粘性来构造一种激波稳定的HLLC格式。分析表明,在熵波粘性和剪切波粘性的作用下,横向的所有扰动都会衰减。一系列数值测试证明了新格式不仅可以成功地抑制各类激波异常现象,还保留了原HLLC格式低耗散性的优点。

关键词：高超声速流 HLLC格式 carbuncle现象熵波粘性剪切波粘性激波不稳定性