检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

新型煤矿救援机器人研发与试验

煤炭学报 2020年第6期45卷 2170-2181页

作者：朱华由韶泽中国矿业大学机电工程学院江苏徐州221116

煤矿救援机器人是一种在矿井发生灾害事故时,替代救护队员进入危险区域进行环境探测和对矿工实施救援的多功能智能救援装备,其应用对提升煤矿灾后救援效率、减少2次伤亡具有重要的意义。以中国矿业大学CUMT-V系列煤矿环境探测与救援机... 详细信息

煤矿救援机器人是一种在矿井发生灾害事故时,替代救护队员进入危险区域进行环境探测和对矿工实施救援的多功能智能救援装备,其应用对提升煤矿灾后救援效率、减少2次伤亡具有重要的意义。以中国矿业大学CUMT-V系列煤矿环境探测与救援机器人的研发为例,从行走机构、防爆设计、结构轻量化、通信方法、传感探测和智能化等方面进行了相关技术和理论研究。针对灾后煤矿的巷道环境特点,推演了机器人行走机构的基本构型,设计了地形适应性好、越障能力强的机器人行走机构;提出并采用基于短时防爆理论的本安兼隔爆的机器人防爆设计技术;提出了基于多腔体自加强结构的机器人轻量化优化设计方法;采用了有线和无线相结合的机器人通信方式;搭建了机器人传感探测与运动控制系统;研发了机器人井下地图构建和定位导航技术。从而研制了能够承载多种探测传感器和急救装备的煤矿灾后环境探测救援机器人,并取得了国家煤矿安全认证。井下应用试验及性能测试结果表明,机器人的行走能力强,能够适用于煤矿非结构复杂地形;机器人续航能力强,通信距离长,环境感知和信息传输的可靠性高;能够通过遥控方式实现机器人的灾后救援;采用有线和无线相结合的机器人通信技术可实现多台机器人的协同救援。通过对机器人进行智能化升级,提高了煤矿救援机器人的环境感知能力,并使其具备了实时定位与自主行走的功能。将上述技术的组合进一步完善,可研发出满足不同应用需求的煤矿环境探测、监控、救援机器人。

关键词：煤矿救援机器人环境探测防爆智能化

Expression of p-PPARγ in the aging thoracic aorta of spontaneously hypertensive rat and inhibitory effect of rosiglitazone

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2014年第12期4卷 977-981页

作者： Hai-Feng Yuan Xiao-Lin Niu Deng-Feng Gao Guang-hua Hao An-Qi Song jin Wei Department of Encephalopathy the Second Affiliated Hospital of Xi'an Jiaotong University Department of Cardiology the Second Affiliated Hospital of Xi'an Jiaotong University Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education Xi'an Jiaotong University

Objective:To investigate the expression of phosphorylated peroxisome proliferators-activated receptor y(p-PPARY) in the aging thoracic aorta of spontaneously hypertensive rat(SHR) and the inhibitory effect of rosiglitazone on the phosphorylation of ***:16,32 and 64 week-old Wistar-Kyoto rats(WKY) and SHR were randomly and respectively divided into WKY,SHR and SHR+rosiglitazone group(9 in each group).The rats in SHR+rosiglitazone group were treated with rosiglitazone(5 mg/kg,intragastrically) for 56 d,whereas normal saline was applied in WKY and SHR *** blood pressure(SBP)of rats was measured by tail cuff *** damage of thoracic aorta was analyzed using Hematoxylin-Eosin(HE) *** staining and western blot were performed to test the level of p-PPARY protein in the thoracic aorta arising from each ***:The SBP in 16,32 and 64 week-old SHR were significantly higher as compared with those in matched WKY rats(P<0.05,respectively).HE staining showed increased content of smooth muscle cell,wrinkled lining endothelium and increased thickness of internal elastic lamina in the thoracic aorta of *** staining and western blot indicated that the levels of p-PPARY in the thoracic aorta arising from SHR were obviously higher than those in the thoracic aorta arising from WKY rats(P<0.05,respectively).Importantly,the high SBP,histopathological abnormalities of the thoracic aorta and elevated p-PPARY expression were prominently abrogated by rosiglitazone treatment in SHR(P<0.05,respectively).Furthermore,the SBP,histopathological abnormalities of the thoracic aorta and p-PPARY expression were positively correlated with age in SHR(P<0.05,respectively).Conclusions:The PPARY phosphorylation was observed in the thoracic aorta of SHR and its expression was increased by the increase of ***,rosiglitazone inhibited the PPARY phosphorylation and suppressed vascular aging in SHR

关键词： P-PPARγ Spontaneously hypertensive rat Thoracic aorta Rosiglitazone Aging

Establishment of a nested-ASP-PCR method to determine the clarithromycin resistance of Helicobacter pylori

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2016年第25期22卷 5822-5830页

作者： Xiao-Feng Luo Jian-hua Jiao Wen-Yue Zhang Han-Ming Pu Bao-jin Qu Bing-Ya Yang Min Hou Min-Jun Ji Department of Pathogen Biology Nanjing Medical University Department of Gastroenterology First Affiliated Hospital of Nanjing Medical University Department of Gastroenterology Nanjing Qixia District Hospital

AIM: To investigate clarithromycin resistance positions 2142, 2143 and 2144 of the 23 Sr RNA gene in Helicobacter pylori(H. pylori) by nested-allele specific primer-polymerase chain reaction(nested-ASP-PCR).METHODS: The gastric tissue and saliva samples from 99 patients with positive results of the rapid urease test(RUT) were collected. The nested-ASP-PCR method was carried out with the external primers and inner allele-specific primers corresponding to the reference strain and clinical strains. Thirty gastric tissue and saliva samples were tested to determine the sensitivity of nested-ASP-PCR and ASP-PCR methods. Then, clarithromycin resistance was detected for 99 clinical samples by using different methods, including nestedASP-PCR, bacterial culture and disk diffusion. RESULTS: The nested-ASP-PCR method was successfully established to test the resistance mutation points 2142, 2143 and 2144 of the 23 SrR NA gene of H. pylori. Among 30 samples of gastric tissue and saliva, the H. pylori detection rate of nested-ASP-PCR was 90% and 83.33%, while the detection rate of ASP-PCR was just 63% and 56.67%. Especially in the saliva samples, nested-ASP-PCR showed much higher sensitivity in H. pylori detection and resistance mutation rates thanASP-PCR. In the 99 RUT-positive gastric tissue and saliva samples, the H. pylori-positive detection rate by nested-ASP-PCR was 87(87.88%) and 67(67.68%), in which there were 30 wild-type and 57 mutated strains in gastric tissue and 22 wild-type and 45 mutated strains in saliva. Genotype analysis showed that three-points mixed mutations were quite common, but different resistant strains were present in gastric mucosa and saliva. Compared to the high sensitivity shown by nested-ASP-PCR, the positive detection of bacterial culture with gastric tissue samples was 50 cases, in which only 26 drug-resistant strains were found through analyzing minimum inhibitory zone of clarithromycin. CONCLUSION: The nested-ASP-PCR assay showed higher detectio

关键词： Helicobacter pylori Nested-allele specific primer-polymerase chain reaction Rapid urease test Clarithromycin resistance Drug sensitivity testing

技术主张的文化响应模式——以法、苏报刊中的控制论论争为中心(1950—1960)

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

自然辩证法研究 2021年第4期37卷 61-66页

作者：朱恬骅上海社会科学院文学研究所上海200235

20世纪50—60年代,控制论在接受过程中的戏剧性差异与变化,集中呈现了文化响应过程中的一般模式。法、苏文艺界报刊的相关材料表明,这种文化相应模式可分为三个阶段,即以政治话语批判为代表的应激策略、以反复设问与例行回答为特征的冲... 详细信息

20世纪50—60年代,控制论在接受过程中的戏剧性差异与变化,集中呈现了文化响应过程中的一般模式。法、苏文艺界报刊的相关材料表明,这种文化相应模式可分为三个阶段,即以政治话语批判为代表的应激策略、以反复设问与例行回答为特征的冲突缓解,和文化借用技术术语的话语同化,实现对技术主张的重新阐释,服务于新论点的建立。文化响应模式至今时有再现,凸显控制论论争的当代意义。

关键词：文化响应控制论话语同化

Supramolecular dendritic polymers for diagnostic and theranostic applications

在线全文

学校读者我要写书评

暂无评论

Science China Materials 2018年第11期61卷 1444-1453页

作者： Yan Wu Guanzhe Xu Xin jin Xinyuan zhu School of Pharmacy Shanghai Jiao Tong UniversityShanghai 200240China School of Chemistry and Chemical Engineering State Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong UniversityShanghai 200240China

Supramolecular dendritic polymers（SDPs）provide a new opportunity for the precision diagnosis and treatment of diseases. SDPs are a novel class of non-covalently bonded macromolecules with highly branched structure and three-dimensional globular topology, which exhibit dynamic/reversible features and unique physical/chemical properties（e.g., high solubility, low viscosity, and numerous functional terminal groups）. The reversibility of non-covalent interactions endows SDPs with the ability of facile preparation, smart responsiveness, and simple metabolism. These special characteristics determine the properties of SDPs, which are the key points for theranostic applications, including diagnosis,therapy, and theranostics. In this review, we briefly summarize the design and synthesis of SDPs with aimed structures,properties, functions as well as their present diagnostic and theranostic applications. These developments on the preparation and applications of SDPs for diagnostic and theranostic purpose promote interdisciplinary research fields of chemistry, material and biomedical science.

关键词： dendritic polymers supramolecular polymers diagnosis therapy theranostics

不同固结压力下聚苯乙烯轻质混合土渗透特性试验研究

在线全文

学校读者我要写书评

暂无评论

岩土力学 2007年第11期28卷 2333-2336,2358页

作者：刘汉龙朱云华董金梅河海大学岩土工程研究所南京210098

通过室内渗透试验,对聚苯乙烯轻质混合土的渗透特性进行了研究,重点对龄期、水泥掺入比及EPS(聚苯乙烯轻质混合土)含量等主要影响因素进行了分析。采用常规三轴仪,进行了不同固结压力下的渗透试验,模拟土体在真实受力状态下渗透系数的... 详细信息

通过室内渗透试验,对聚苯乙烯轻质混合土的渗透特性进行了研究,重点对龄期、水泥掺入比及EPS(聚苯乙烯轻质混合土)含量等主要影响因素进行了分析。采用常规三轴仪,进行了不同固结压力下的渗透试验,模拟土体在真实受力状态下渗透系数的变化。结果表明,渗透系数随水泥掺入比、龄期、固结压力的增大及EPS含量的降低而降低,近似为乘幂函数关系,但其降低的幅度因配比及龄期不同而异。

关键词：聚苯乙烯轻质混合土渗透系数龄期水泥掺入比 EPS含量固结压力

在线全文

学校读者我要写书评

暂无评论

共犯本质:一个反思性检讨

西北大学学报（哲学社会科学版） 2008年第2期38卷 80-87页

作者：朱道华武汉大学法学院湖北武汉430072

共犯从属性说、独立性说与二重性说一致认为:共同犯罪是数人共犯一罪,共同犯罪行为是数人共为一个整体的犯罪行为。这三种学说面临的共同问题是其都不能正确揭示行为、罪数与处罚之间的辨证关系。根据犯罪构成基本理论,共同犯罪行为是... 详细信息

共犯从属性说、独立性说与二重性说一致认为:共同犯罪是数人共犯一罪,共同犯罪行为是数人共为一个整体的犯罪行为。这三种学说面临的共同问题是其都不能正确揭示行为、罪数与处罚之间的辨证关系。根据犯罪构成基本理论,共同犯罪行为是数人数行为而不是数人共为一个整体的犯罪行为;共同犯罪是数人数罪而不是数人一罪。将正犯的实行行为评价为共犯行为的一部分不仅可能而且正当。只有将共同犯罪界定为数人共犯数罪,才能彻底厘清共同犯罪与犯罪构成之间的辩证关系,从而能够维护整个刑法理论体系的完整性与科学性。

关键词：共同犯罪数行为数罪刑法

Introduction of ZnO,Sn,and P promoters in CuO/CeO_(2) catalysts for improved production of dimethyldichlorosilane in the Rochow-Müller reaction

在线全文

学校读者我要写书评

暂无评论

Resources Chemicals and Materials 2022年第3期1卷 249-260页

作者： Xinyang Li Yongxia zhu Baofang jin Yongjun Ji Lei Shi Dongxing Fu Dingrong Bai Fabing Su Key Laboratory on Resources Chemicals and Materials(Shenyang University of Chemical Technology) Ministry of EducationShenyang 110142China State Key Laboratory of Multiphase Complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Light Industry Beijing Technology and Business UniversityBeijing 100048China Institute of Industrial Chemistry and Energy Technology Shenyang University of Chemical TechnologyShenyang 110142China Gripm Research Institute Co. Ltd.Beijing 101407China

Developing an efficiently supported Cu-based catalyst with promoters to substitute the existing non-supported Cu-based catalysts is highly desirable to the Rochow-Müller reaction. Using a simple ball-milling method and CeO_(2) support, we prepared a high-performance CuO-ZnO-P-Sn/CeO_(2) catalyst by integrating highly dispersed multicomponent promoters of ZnO, Sn, and P with the active component CuO. This catalyst shows a significantly enhanced dimethyldichlorosilane selectivity because these promoters can substantially increase the Cu+ content and the formation of an active CuxSi phase. This work provides a new approach to efficiently designing Cu-based catalysts for the Rochow-Müller reaction.

关键词： Rochow-Miller reaction CuO/CeO_(2)catalyst Promoters Heterogene0us catalysis Solid-phase synthesis

Searching for initial stage of massive star formation around the HⅡ region G18.2–0.3

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2017年第6期17卷 77-88页

作者： Chuan-Peng Zhang jing-hua Yuan jin-Long Xu Xiao-Lan Liu Nai-Ping Yu Nan Li Li-Ping He Guo-Yin Zhang Jun-Jie Wang National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China

Sometimes, early star formation can be found in cold and dense molecular clouds, such as an infrared dark cloud. Considering that star formation often occurs in clusters, H II regions may be triggering a new generation of star formation, so we can search for the initial stage of massive star formation around H II regions. Based on the above, this work introduces one method to search for the initial stage of massive star formation around H II regions. Towards one section of the H II region G18.2-0.3, multiwavelength observations are carried out to investigate its physical properties. Through analysis, we find three potential initial stages of massive star formation, suggesting that it is feasible to use in searching for the initial stage of massive star formation around H II regions.

关键词： infrared stars - stars formation - initial stage - H II regions