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Necroptosis plays a crucial role in the exacerbation of retinal injury after blunt ocular trauma

Neural Regeneration Research 2023年第4期18卷 922-928页

作者： Yu Huan xiu-Quan Wu Tao Chen Ya-Nan Dou Bo jia Xin He Dong-Yu Wei zhou Fei Fei Fei Department of Neurosurgery Xijing HospitalAir Force Medical UniversityXi’anShaanxi ProvinceChina Center of Clinical Aerospace Medicine Air Force Medical UniversityXi’anShaanxi ProvinceChina Department of Aviation Medicine Xijing HospitalAir Force Medical UniversityXi’anShaanxi ProvinceChina Department of Ophthalmology Xijing HospitalAir Force Medical UniversityXi’anShaanxi ProvinceChina

Retinal injury after blunt ocular trauma may directly affect prognosis and lead to vision *** investigate the pathological changes and molecular mechanisms involved in retinal injury after blunt ocular trauma,we established a weight drop injury model of blunt ocular trauma in male Beagle ***-eosin staining,immunofluorescence staining,western blotting,and TUNEL assays were performed to investigate retinal injury within 14 days after blunt ocular *** with the control group,the thicknesses of the inner and outer nuclear layers,as well as the number of retinal ganglion cells,gradually decreased within 14 days after *** number of bipolar cells in the inner nuclear layer began to decrease 1 day after injury,while the numbers of cholinergic and amacrine cells in the inner nuclear layer did not decrease until 7 days after ***,retinal cell necroptosis increased with time after injury;it progressed from the ganglion cell layer to the outer nuclear *** electrophysiological findings indicated that visual impairment began on the first day after injury and worsened over ***,blunt ocular trauma induced nerve regeneration and Müller glial hyperplasia;it also resulted in the recruitment of microglia to the retina and polarization of those microglia to the M1 *** findings suggest that necroptosis plays an important role in exacerbating retinal injury after blunt ocular trauma via gliosis and *** a role has important implications for the development of therapeutic strategies.

关键词： Beagle dogs blunt ocular trauma gliosis M1 microglia Müller cells necroptosis neuroinflammation retinal ganglion cells retinal injury weight drop injury

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Enhancing low-temperature NO_x storage and reduction performance of a Pt-based lean NO_x trap catalyst

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Rare Metals 2019年第1期38卷 81-86页

作者： Tong Wang Li-Wei jia xiu-Ting Wang Gang Wang Fu-Qiang Luo jia-Ming Wang School of Automotive and Traffic Engineering Jiangsu University Wuxi Weifu Environmental Catalysts Co. Ltd

Two lean NO_x trap(LNT) catalysts, Pt/BaO/CeO_2 + Al_2O_3 and Pt/BaO/CeO_2-Al_2O_3, were prepared and compared for low-temperature(< 250℃) NO_x storage and reduction performance. The influence of the form of ceria on low-temperature NO_x storage and reduction performance of LNT catalysts was investigated with the focus on NO_x storage capacity, NO_x reduction efficiency during lean/rich cycling, product selectivity and thermal *** coupled plasma-atomic emission spectrometry(ICP-AES), Brunner-Emmet-T eller(BET), H_2-pulse chemisorption and X-ray diffraction(XRD) were conducted to characterize the physical properties of LNT catalysts. NO_x storage capacity and NO_x conversion efficiency were measured to evaluate NO_x storage and reduction performance of LNT catalysts. Pt/BaO/CeO_2-Al_2O_3 catalyst exhibits higher NO_x storage capacity than Pt/BaO/CeO_2 + Al_2O_3 catalyst in the temperature range of 150-250 ℃. Meanwhile, Pt/BaO/CeO_2-Al_2O_3 catalyst shows better NO_x conversion efficiency and N_2 selectivity. XRD results indicate that the thermal stability of CeO_2-Al_2O_3 complex oxide is superior to that of pure CeO_2. H_2-pulse chemisorption results show that Pt/BaO/CeO_2-Al_2O_3 catalyst has higher Pt dispersion than Pt/BaO/CeO_2 + Al_2O_3 catalyst over fresh and aged samples. The improved physical properties of Pt/BaO/CeO_2-Al_2O_3 catalyst are attributed to enhance the NOx storage and reduction performance over Pt/BaO/CeO_2 + Al_2O_3 catalyst.

关键词： NOx storage and reduction Low temperature Ceria Ceria-alumina LNT

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Urban natural gas demand and factors analysis in China:Perspectives of price and income elasticities

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Petroleum Science 2022年第1期19卷 429-440页

作者： jia-Man Li xiu-Cheng Dong Qin-Zhe jiang Kang-Yin Dong School of International Trade and Economics University of International Business and EconomicsBeijing100029China UIBE Belt&Road Energy Trade and Development Center University of International Business and EconomicsBeijing100029China

Urban natural gas is becoming the main sector driving China’s natural gas consumption growth in recent *** study explores the impacts of urban natural gas price,wage,socioeconomic determinants,and meteorological conditions on urban natural gas demand in China over ***,this study also analyzes the potential regional heterogeneity and asymmetry in the impacts of gas price and income on China’s urban gas *** results reveal that:(1)The increased gas price can significantly reduce the urban gas demand,and the average income level may effectively promote the gas demand,also,a strong switching effect exists between electricity and natural gas in urban China;(2)these impacts are heterogeneous in regions among China,urban natural gas demand is largely affected by the gas price in regions with high-gas-price and by income in regions with low-gas-price;and(3)the impact of gas price on urban gas consumption is consistent in regions with different urban natural gas consumption,while the impact of income is *** study further provides several policy implications for improving the urban natural gas industry in China.

关键词： Urban natural gas demand Natural gas price Average wage Regional heterogeneity Asymmetry analysis

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The Effect of Wheat Mixtures on the Powdery Mildew Disease and Some Yield Components

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Journal of Integrative Agriculture 2012年第4期11卷 611-620页

作者： LI Ning jia Shao-feng WANG xiu-na DUAN Xia-yu zhou Yi-lin WANG Zong-hua LU Guo-dong State Key Laboratory for Biology of Plant Disease and lnsect Pests Institute of Plant Protection Chinese Academy of Agricultural Sciences Beijing 100193 P.R.China School of Life Sciences Fujian Agriculture and Forestry University Fuzhou 350002 P.R. China

Mixtures composed of five wheat cultivars,Jingshuang 16,Jing 411,Jingdong 8,Lunxuan 987,and Baofeng 104,with different levels of resistance against powdery mildew were tested for their potential containment of the disease development in the field and for the influence on grain yield and the content of crude protein in the years 2007 and *** plots were inoculated artificially with mixed isolates collected in the fields and propagated in the greenhouse and the disease was scored in 7 d interval during the two growing *** was indicated that certain combinations,e.g.,Jingdong 8：Lunxuan 987,Jingdong 8：Baofeng 104,and Jing 411：Jingdong 8：Baofeng 104,showed positive efficacy on the *** cultivar combinations tested in 2007 showed increase of grain yield,while most of the combinations tested in 2010 did not show the *** differences of the increases or decreases were not statistically significant except combinations Jing 411：Jingdong 8：Baofeng104,Jingshuang16：Jingdong8：Lunxuang 987 and Jingshuang 16：Jingdong 8：Lunxuan 987：Baofeng 104,which showed the decrease of the grain *** mixtures did not show influence on the content of crude protein in *** cultivar combinations need to be tested.

关键词： wheat powdery mildew cultivar mixture AUDPC yield crude protein

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Carbon Mineralization and Microbial Attributes in Straw-Amended Soils as Affected by Moisture Levels

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Pedosphere 2014年第2期24卷 167-177页

作者： CHEN Lin ZHANG jia-Bao ZHAO Bing-Zi XIN xiu-Li zhou Gui-Xiang TAN Jin-Fang ZHAO Jin-Hua State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of Sciences University of Chinese Academy of Sciences Collaborative Innovation Center of Food Crops in Henan Henan Agriculture University

An 80-d incubation experiment was conducted to investigate straw decomposition, the priming effect and microbial characteristics in a non-fertilized soil （soil 1） and a long-term organic manure-fertilized soil （soil 2） with and without 13C-labeled maize straw amendment under different moisture levels. The soil 2 showed a markedly higher priming effect, microbial biomass C （Cmic）, and β-glucosidase activity, and more abundant populations of bacteria and fungi than the soil 1. Also, soil CO2 emission, Cmic, /3- glucosidase activity, and bacterial and fungal population sizes were substantially enhanced by straw amendment. In the presence of straw, the amount of straw mineralization and assimilation by microbes in the soil at 55% of water holding capacity （WHC） were significantly higher by 31% and 17%, respectively, compared to those at 25% of WHC. In contrast, β-glucosidase activity and fungal population size were both enhanced as the moisture content decreased. Cmic decreased as straw availability decreased, which was mainly attributed to the reduction of straw-derived Cmic. Amended soils, except the amended soil 2 at 25% of WHC, had a more abundant fungal population as straw availability decreased, indicating that fungal decomposability of added straw was independent of straw availability. Non-metric multidimensional scaling analysis based on fungal denatured gradient gel electrophoresis band patterns showed that shifts in the fungal community structure occurred as water and straw availability varied. The results indirectly suggest that soil fungi are able to adjust their degradation activity to water and straw availability by regulating their community structure.

关键词： bacteria decomposition fungi maize straw organic manure

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Two New Antibacterial Iridoids from Patrinia rupestris

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Chinese Chemical Letters 2006年第3期17卷 337-340页

作者： xiu Ping YANG Cheng Shan YUAN Zhong jian jia State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University Lanzhou 730000

Two new iridoids （1 and 2） were isolated from the roots of Patrinia rupestris （Pail.） Juss. Their structures were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited strong antibacterial activities ag... 详细信息

关键词： Patrinia rupestris Valerianaceae iridoids antibacterial activity.

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Changes of matrix metalloproteinases in the stroma after corneal cross-linking in rabbits

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International Journal of Ophthalmology(English edition) 2021年第1期14卷 26-31页

作者： Hong-Zhen jia Xu Pang xiu-Jun Peng Department of Ophthalmology the Sixth Medical Center of Chinese PLA General HospitalBeijing 100048China

AIM:To observe changes in the content of matrix metalloproteinases(MMPs)in the corneal stroma after corneal cross-linking(CXL)in rabbits,and further explore the corneal pathophysiological process after ***:Forty-two rabbits(42 eyes)were randomly divided into seven *** group served as the control group,while the other six groups were treated with *** concentrations of MMPs in corneal stroma were evaluated through parallel reaction monitoring at baseline and 3,7,15,30,90,and 180 d after ***:The levels of MMP-2 in the corneal stroma of rabbits were 0.76±0.07,2.78±1.39,4.12±0.69,2.00±0.29,2.00±0.30,1.22±0.18,and 1.35±0.18(10^(-9)mol/g)at baseline and 3,7,15,30,90,and 180 d after treatment,*** contents of tissue inhibitor of metalloproteinase-1(TIMP-1)were 1.83±0.26,7.94±0.58,6.95±2.64,3.81±0.48,3.07±0.92,1.72±0.19,and 1.69±0.74(10^(-9)mol/g),*** ratios of MMP-2/TIMP-1 were 0.42±0.33,0.36±0.20,0.62±0.10,0.54±0.15,0.68±0.13,0.71±0.10,and 0.68±0.09,*** CXL,the expression of MMP-2 and TIMP-1 in the rabbit corneal stroma was initially increased and subsequently *** levels of MMP-2 remained higher than those recorded at baseline 180 d after treatment,but it was not statistically *** levels of TIMP-1 returned to baseline levels at 90 d after *** ratio of MMP-2/TIMP-1 started to rise from 7 d after *** was significantly higher than that calculated at baseline 30-180 d after *** results for MMP-1,-3,-7,-9,-13,and TIMP-2 were ***:CXL can lead to changes in the content of MMP-2 and TIMP-1 in the rabbit corneal *** ratio of MMP-2/TIMP-1 remains higher versus baseline,indicating that MMP-2 is involved in the corneal pathophysiological process after CXL.

关键词： corneal cross-linking keratoconus rabbit riboflavin matrix metalloproteinase

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Efficient catalyst-free chemical fixation of carbon dioxide into 2-oxazolidinones under supercritical condition

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Chinese Chemical Letters 2011年第9期22卷 1063-1066页

作者： Jing xiu Xu Jin Wu Zhao Zhen Bin jia School of Pharmacy Guangdong Medical College Dongguan 523808 China

4-Methylene-1,3-oxazolidin-2-ones can be synthesized from propargylic alcohols, primary amines and carbon dioxide under supercritical condition in the absence of any additional catalyst and solvent. Various propargyli... 详细信息

关键词： Catalyst-free Carbon dioxide Supercritical 2-Oxazolidinone

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High Precision Prediction of Rolling Force Based on Fuzzy and Nerve Method for Cold Tandem Mill

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Journal of Iron and Steel Research International 2008年第2期15卷 23-27页

作者： jia Chun-yu SHAN xiu-ying NIU Zhao-ping College of Mechanical Engineering Yanshan University Qinhuangdao 066004 Hebei China

The rolling force model for cold tandem mill was put forward by using the Elman dynamic recursive network method,based on the actual measured ***,a good assumption is put forward,which brings a full universe of discourse self-adjusting factor fuzzy control,closed-loop adjusting,based on error feedback and expertise into a rolling force prediction model,to modify prediction outputs and improve prediction precision and *** simulated results indicate that the method is highly effective and the prediction precision is better than that of the traditional *** relative error is less than ±4%,so the prediction is high precise for the cold tandem mill.

关键词： Elman dynamic recursive network fuzzy control cold tandem mill rolling force prediction

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Two New Bisabolane Sesquiterpenes from Leontopodium longifolium

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Chinese Chemical Letters 2006年第6期17卷 776-778页

作者： Ji Xin LI xiu Ping YANG Zhong jian jia State Key Laboratory of Applied Organic Chemistry College of Chemistry and Engineering Lanzhou University Lanzhou 730000

Two new bisabolane sesquiterpenes were isolated from the roots of Leontoptdium longifolium. Their structures were elucidated as 4α, 5α-diacetoxy-lα-angeloyloxybisabol-2, 9, ll-triene and 4α, 5α-diacetoxy-lα-ange... 详细信息

关键词： Leontopodium longifolium Compositae bisabolane sesquiterpene.

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