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Strain engineering of anisotropic light-matter interactions in onedimensional P-P chain of SiP_(2)

Nano Research 2022年第8期15卷 7378-7383页

作者： Fanghua Cheng Junwei Huang Feng Qin Ling Zhou Xueting Dai Xiangyu bi Caorong Zhang Zeya Li Ming Tang Caiyu Qiu Yangfan Lu Huiyang Gou Hongtao Yuan National Laboratory of Solid State Microstructures and Jiangsu Key Laboratory of Artificial Functional Materials College of Engineering and Applied SciencesNanjing UniversityNanjing 210000China College of Materials Science and Engineering National Engineering Research Center for Magnesium AlloysChongqing UniversityChongqing 400030China Center for High Pressure Science and Technology Advanced Research Beijing 100094China

Strain engineering can serve as a powerful technique for modulating the exotic properties arising from the atomic structure of *** have been demonstrated that one-dimensional(1D)structure can serve as a great platform for modulating electronic band structure and phonon dispersion via strain ***,in a van der Waals material silicon diphosphide(SiP_(2)),quasi-1D zigzag phosphorus–phosphorus(P–P)chains are embedded inside the crystal structure,and can show unique phonon vibration modes and realize quasi-1D *** those optical properties by the atom displacements via strain engineering is of great interest in understanding underlying mechanism of such P–P chains,however,which remains ***,we demonstrate the strain engineering of Raman and photoluminescence(PL)spectra in quasi-1D P–P chains and resulting in anisotropic manipulation in SiP_(2).We find that the phonon frequencies of SiP_(2)in Raman spectra linearly evolve with a uniaxial strain along/perpendicular to the quasi-1D P–P chain ***,by applying tensile strain along the P–P chains,the band gap energy of strained SiP_(2)can significantly decrease with a tunable value of~55 *** on arsenic(As)element doping into SiP_(2),the strain-induced redshifts of phonon frequencies decrease,indicating the stiffening of the phonon vibration with the increased arsenic doping *** results provide an opportunity for strain engineering of the light–matter interactions in the quasi-1D P–P chains of SiP_(2)crystal for potential optical applications.

关键词： strain engineering silicon diphosphide Raman photoluminescence

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Resistance Level and Metabolism of Barnyard-Grass (Echinochloa crusgalli(L.) Beauv.) Populations to Quizalofop-p-ethyl in Heilongjiang Province,China

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Agricultural Sciences in China 2011年第12期10卷 1914-1922页

作者： HUAN Zhi-bo ZHANG Hong-jun HOU Zhen ZHANG Shao-yi ZHANG Yang LIU Wei-tang bi Ya-ling WANG Jin-xin College of Plant Protection Shandong Agricultural University Tai ＇an 271018 P.R. China Institute for the Control of Agrochemicals Ministry of Agriculture Beijing 100125 P.R.China

Eleven barnyardgrass populations were assayed. The highest resistant population was Geqiushan R with RI 125.45 resulted from the seed assay and 87.29 resulted from the whole plant bioassay followed by 853 R with RI 2.79 resulted from the seed assay and 6.04 resulted from the whole plant bioassay. The resistance level of other nine populations was low with RI 1.13-2.61 resulted from the seed assay and 1.48-3.63 resulted from the whole plant bioassay. The activity of an important metabolic enzyme glutathione S-transferases （GSTs） and three protective enzymes （SOD, POD, and CAT） were determined in vivo for Geqiushan R, 853 R, and Wudalianchi R. Compared with the S controls, the activities of POD in Geqiushan R, GSTs in 853 R, and Wudalianchi R were increased.

关键词： barnyard-grass Echinochloa crusgalli quizalofop-p-ethyl resistance level metabolism

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Association of keratin 8/18 variants with non-alcoholic fatty liver disease and insulin resistance in Chinese patients: A case-control study

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World Journal of Gastroenterology 2017年第22期23卷 4047-4053页

作者： Rui Li Xian-Hua Liao Jun-Zhao Ye Min-Rui Li Yan-Qin Wu Xuan Hu bi-Hui Zhong Department of Gastroenterology The First Affiliated Hospital of Sun Yat-Sen University

AIM To test the hypothesis that K8/K18 variants predispose humans to non-alcoholic fatty liver disease(NAFLD) progression and its metabolic phenotypes. METHODS We selected a total of 373 unrelated adult subjects from our Physical Examination Department, including 200 unrelated NAFLD patients and 173 controls of both genders and different ages. Diagnoses of NAFLD were established according to ultrasonic signs of fatty liver. All subjects were tested for population characteristics, lipid profile, liver tests, as well as glucose tests. Genomic DNA was obtained from peripheral blood with a DNeasy Tissue Kit. K8/K18 coding regions were analyzed, including 15 exons and exon-intron boundaries. RESULTS Among 200 NAFLD patients, 10(5%) heterozygouscarriers of keratin variants were identified. There were 5 amino-acid-altering heterozygous variants and 6 non-coding heterozygous variants. One novel aminoacid-altering heterozygous variant(K18 N193S) and three novel non-coding variants were observed(K8 IVS5-9A→G, K8 IVS6+19G→A, K18 T195T). A total of 9 patients had a single variant and 1 patient had compound variants(K18 N193S+K8 IVS3-15C→G). Only one R341 H variant was found in the control group(1 of 173, 0.58%). The frequency of keratin variants in NAFLD patients was significantly higher than that in the control group(5% vs 0.58%, P = 0.015). Notably, the keratin variants were significantly associated with insulin resistance(IR) in NAFLD patients(8.86% in NAFLD patients with IR vs 2.5% in NAFLD patients without IR, P = 0.043).CONCLUSION K8/K18 variants are overrepresented in Chinese NAFLD patients and might accelerate liver fat storage through IR.

关键词： Keratin Variant Non-alcoholic fatty liver disease Insulin resistance Chinese population

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Dyeing bacterial cellulose pellicles for energetic heteroatom doped carbon nanofiber aerogels

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Nano Research 2014年第12期7卷 1861-1872页

作者： Zhen-Yu Wu Hai-Wei Liang Chao Li bi-Cheng Hu Xing-Xing Xu Qing Wang Jia-Fu Chen Shu-Hong Yu Division of Nanomaterials and Chemistry Hefei National Laboratory for Physical Sciences at Microscale Collaborative InnovationCenter of Suzhou Nano Science and Technology Department of Chemistry University of Science and Technology of China HefeiAnhui 230026 China

The energy crisis and environmental pollution are serious challenges that humanity will face for the long-term. Despite tremendous efforts, the development of environmentally friendly methods to fabricate new energy materials is still challenging. Here we report, for the first time, a new strategy to fabricate various doped carbon nanofiber （CNF） aerogels by pyrolysis of bacterial cellulose （BC） pellicles which had adsorbed or were dyed with different toxic organic dyes. The proposed strategy makes it possible to remove the toxic dyes from waste-water and then synthesize doped CNF aerogels using the dyed BC pellicles as precursors. Compared with other reported processes for preparing heteroatom doped carbon （HDC） nanomaterials, the present synthetic method has some significant advantages, such as being green, general, low-cost and easily scalable. Moreover, the as-prepared doped CNF aerogels exhibit great potential as electrocatalysts for the oxygen reduction reaction （ORR） and as electrode materials for supercapacitors.

关键词： doped carbon nanofiberaerogels electrocatalysts oxygen reduction reaction supercapacitors organic dyes bacterial cellulose

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抽水蓄能机组水轮机工况启动过程转轮动应力特性

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大电机技术 2024年第1期 8-14页

作者：陈志明靳发业林恺毕慧丽王焕茂罗永要南方电网储能股份有限公司广州510635 水圈科学与水利工程全国重点实验室(清华大学) 北京100084 清华大学能源与动力工程系北京100084 水力发电设备全国重点实验室(哈尔滨电机厂有限责任公司) 哈尔滨150040 哈尔滨电机厂有限责任公司哈尔滨150040 哈尔滨大电机研究所哈尔滨150040

本文以某原型水泵水轮机组为研究对象,研究了水轮机工况启动过程中外特性的动态变化曲线,重点分析水泵水轮机转轮内流场和动应力特性。研究结果表明,在水轮机工况启动过程中,转轮扭矩呈先上升后下降的趋势,在转速达到额定值时,扭矩接近... 详细信息

本文以某原型水泵水轮机组为研究对象,研究了水轮机工况启动过程中外特性的动态变化曲线,重点分析水泵水轮机转轮内流场和动应力特性。研究结果表明,在水轮机工况启动过程中,转轮扭矩呈先上升后下降的趋势,在转速达到额定值时,扭矩接近于0;流量受到导叶开度的影响非常明显,处于先上升后下降趋势;水头在430~480m左右波动。随着转速的增加,转轮流固耦合面上的整体压力值显著增加。高压区起始集中在转轮进水边的压力面一侧,随着时间的推移,高压区域逐渐扩大并移动到进水边的吸力面一侧。转轮进水边与下环交接处的应力呈现先下降后上升的趋势,应力均值下降的同时,峰峰值也有所下降,应力值一直处于较低的水平。转轮进水边与上冠交接处的应力呈现上升趋势,并与转轮转速的变化趋势一致。本文对于深入理解水泵水轮机组启动过程复杂条件下的内部流动和转轮动应力特性具有重要参考价值。

关键词：抽水蓄能机组水轮机工况启动过程数值模拟动网格转轮动应力

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慕课与Seminar文献研读联合教学法在牙体牙髓科住院医师规范化培训中的应用

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牙体牙髓牙周病学杂志 2024年第9期29卷 555-558页

作者：于雅琼薛明毕欣欣刘昕阳孙海燕仇丽鸿辽宁省口腔疾病重点实验室/中国医科大学口腔医学院/中国医科大学附属口腔医院牙体牙髓科辽宁沈阳110002 中国医科大学口腔医学院/中国医科大学附属口腔医院毕业后培训部辽宁沈阳110002

目的:探讨慕课与Seminar文献研读联合教学法在牙体牙髓科住院医师规范化培训(以下简称住培)中的作用。方法:以2021年01月至06月和2022年01月至06月的在中国医科大学附属口腔医院牙体牙髓科参加住培的40名住培学生为研究对象。其中,选择2... 详细信息

目的:探讨慕课与Seminar文献研读联合教学法在牙体牙髓科住院医师规范化培训(以下简称住培)中的作用。方法:以2021年01月至06月和2022年01月至06月的在中国医科大学附属口腔医院牙体牙髓科参加住培的40名住培学生为研究对象。其中,选择2021年的20名住培学生为对照组,采用传统教学法。2022年的20名住培学生为观察组,在传统教学模式基础上,增加慕课与Seminar文献研读联合教学法。比较两组住培学生的出科考核成绩,并进行教学满意度问卷调查。结果:观察组住培学生的出科考试理论成绩的平均分明显高于对照组(P<0.05),采用慕课与Seminar文献研读联合教学法的观察组住培生的住院医师岗位胜任力的多方面评价均高于采用传统教学方法的对照组住培学生(P<0.05)。结论:在牙体牙髓科住培中引入慕课与Seminar文献研读联合教学法能显著提高教学效果。

关键词：慕课 Seminar教学法牙体牙髓病学住院医师规范化培训文献研读

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恶性胸膜间皮瘤细胞培养条件及CDKN2B对癌细胞的作用

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昆明医科大学学报 2024年第1期45卷 28-34页

作者：尹小川尹瑞扬李冉华蔡方奇崔岳毕涛童兴和昆明医科大学第一附属医院胸外科云南昆明650032 昆明医科大学海源学院第二临床医学系云南昆明651700

目的探讨不同培养条件(RPMI-1640、DMEM和DMEM/F12培养液)对人恶性胸膜间皮瘤(malignant pleural mesothelioma,MPM)组织中分离的MPM细胞传代的影响以及细胞周期蛋白依赖性激酶抑制剂2B(cyclin dependent kinase inhibitor 2B,CDKN2B)对MPM细胞增殖、侵袭和凋亡的作用。方法从MPM组织中分离细胞分别用RPMI-1640、DMEM和DMEM/F12培养液培养。CCK-8检测细胞增殖,细胞核及染色体利用瑞氏-吉姆萨染色观察,免疫荧光实验检测MPM标志物Calretinin、CD141、CK5、EMA和WT-1荧光强度。RT-qPCR和Western blot分别检测CDKN2B的mRNA和蛋白表达能力。Transwell检测细胞侵袭能力,流式细胞术检测细胞凋亡率。结果建立的MPM细胞在RPMI-1640、DMEM和DMEM/F12培养液中传至第10代仍具有较好的活力,且MPM标志物Calretinin、CD141、CK5、EMA和WT-1在细胞中均表达,MPM细胞在RPMI-1640培养液中活力较为稳定。CDKN2B在MPM细胞中低表达(P<0.05),过表达CDKN2B显著抑制MPM细胞的增殖(P<0.05)、侵袭(P<0.05)和上皮间质转化(P<0.01),促进细胞凋亡(P<0.01)。结论建立的MPM细胞可在RPMI-1640培养液中稳定传代,CDKN2B可作为MPM诊断和治疗的潜在靶标。

关键词：恶性胸膜间皮瘤培养条件 RPMI-1640培养液 CDKN2B 增殖侵袭

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Prevalence of High-Risk Human Papillomavirus in Cervical Intraepithelial Neoplasia in the Pre-Vaccine Era—China,2017–2018

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China CDC weekly 2022年第48期4卷 1083-1087页

作者： Heling Bao Weihong Chen Xiaosong Zhang Hui bi Yun Zhao Liwen Fang Shu Cong Feng Tan Linhong Wang Institute of Medical Information Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina National Center for Chronic and Non-communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Chinese Center for Disease Control and Prevention BeijingChina Department of Obstetrics and Gynecology Peking University First HospitalBeijingChina Department of Obstetrics and gynecology Peking University People’s HospitalBeijingChina.&Joint first authors.

What is already known about this topic?Human papillomavirus(HPV)type-specific strategies play a key role in the prevention of cervical intraepithelial neoplasia(CIN),but evidence on the HPV type-specific prevalence in CIN is *** is added by this report?This multicentric study estimates the prevalence of high-risk HPV types in CIN cases and the associations of HPV infection patterns with high-grade CIN in China in 2017–*** are the implications for public health practice?Population-based prevention strategies should give preference to HPV-16 and 18,and strategies for non-16/18 high-risk HPV are essential for the elimination of cervical cancer.

关键词： prevention prevalence cervical

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一种近邻局部学习的稳健性分析

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模式识别与人工智能 2008年第6期21卷 768-774页

作者：毕华王珏中国科学院自动化研究所复杂系统与智能科学重点实验室北京100190

在统计推断中,稳健性是指实际问题的数据来源与我们的模型假定有偏离时,所采用算法的结果受到的扰动很小,并且保持算法的预测性能.本文将统计稳健性的研究方法引入机器学习中,分析得到近邻估计这种局部学习能够在大样本的情形下收敛到 B... 详细信息

在统计推断中,稳健性是指实际问题的数据来源与我们的模型假定有偏离时,所采用算法的结果受到的扰动很小,并且保持算法的预测性能.本文将统计稳健性的研究方法引入机器学习中,分析得到近邻估计这种局部学习能够在大样本的情形下收敛到 Bayes 最优估计,同时收敛条件可说明近邻估计是稳健估计.在模拟数据和真实数据库上进行实验,结果表明在某些离群点影响模型的情况下,仍保持监督学习预测的泛化性能.

关键词：局部学习稳健性噪音数据

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Development of the readout system for waveguide multilayer optical card

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Optoelectronics Letters 2008年第2期4卷 150-152页

作者： GU Min-fen LIANG Zhong-cheng WANG Ren-zhou DONG Xiang-mei ZHANG Pei-ming CHEN Jia-bi College of Mathematics ＆ Physics Nanjing University of Posts ＆ Telecommunications Nanjing 210003 China Jiangsu Key Lab. of Optoelectronic Technology Nanjing Normal University Nanjing 210097 China College of Optics and Electronics Information Engineering Shanghai University for Science and Technology Shanghai 200093 China

Waveguide multilayer optical card (WMOC) is a novel storage device of three-dimensional optical information. An advanced readout system fitting for the WMOC is introduced in this paper. The hardware mainly consists of the light source for reading, WMOC, motorized stages addressing unit, microscope imaging unit, CCD detecting unit and PC controlling & processing unit. The movement of the precision motorized stage is controlled by the computer through Visual Basic (VB) language in software. A control panel is also designed to get the layer address and the page address through which the position of the motorized stages can be changed. The WMOC readout system is easy to manage and the readout result is directly displayed on computer monitor.

关键词：读出系统波导光学卡存贮器

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