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Identifying the Hydrochemical Characteristics,Genetic Mechanisms and Potential Human Health Risks of Fluoride and Nitrate Enriched Groundwater in the Tongzhou District,Beijing,North China

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Acta Geologica Sinica(English Edition) 2024年第2期98卷 468-476页

作者： zhang Shouchuan LIU kai MA Yan WANG Luyao SUN Junliang Chinese Academy of Geological Sciences Beijing 100037China School of Water Resources and Environment China University of Geosciences(Beijing)Beijing 100083China

Fluoride and nitrate enriched groundwater are potential threats to the safety of the groundwater supply that may cause significant effects on human health and public safety,especially in aggregated population areas and economic *** study focuses on the high F^(−)and NO_(3)^(−)concentration groundwater in Tongzhou District,Beijing,North China.A total of 36 groundwater samples were collected to analyze the hydrochemical characteristics,elucidate genetic mechanisms and evaluate the potential human health *** results of the analysis indicate:Firstly,most of the groundwater samples are characterized by Mg-HCO_(3) and Na-HCO_(3) with the pH ranging from 7.19 to 8.28 and TDS with a large variation across the range 471-2337 mg/*** NO_(3)^(−)concentration in 38.89%groundwater samples and the F^(−)concentration in 66.67%groundwater samples exceed the permissible limited ***,F^(−)in groundwater originates predominantly from water-rock interactions and the fluorite dissolution,which is also regulated by cation exchange,competitive adsorption of HCO_(3)−and an alkaline ***,the effect of sewage disposal and agricultural activities have a significant effect on high NO3-concentration,while the high F^(−)concentration is less influenced by anthropogenic *** alkaline environment favors nitrification,thus being conducive to the production of NO_(3)^(−).Finally,the health risk assessment is evaluated for different population *** results indicate that high NO_(3)^(−)and F^(−)concentration in groundwater would have the largest threat to children’s *** findings of this study could contribute to the provision of a scientific basis for groundwater supply policy formulation relating to public health in Tongzhou District.

关键词： fluoride concentration nitrate pollution genetic mechanism health risk assessment Tongzhou District

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Electrolyte Design for Low‑Temperature Li‑Metal Batteries:Challenges and Prospects

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Nano-Micro Letters 2024年第2期16卷 365-382页

作者： Siyu Sun Kehan Wang zhanglian Hong Mingjia Zhi kai zhang Jijian Xu Department of Chemistry City University of Hong KongHong Kong 999077People’s Republic of China State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China State Key Laboratory of Advanced Chemical Power Sources Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education)Haihe Laboratory of Sustainable Chemical TransformationsCollaborative Innovation Center of Chemical Science and Engineering(Tianjin)College of ChemistryNankai UniversityTianjin 300071People’s Republic of China Department of Chemical and Biomolecular Engineering University of Maryland College ParkCollege ParkMD 20742USA

Electrolyte design holds the greatest opportunity for the development of batteries that are capable of sub-zero temperature *** get the most energy storage out of the battery at low temperatures,improvements in electrolyte chemistry need to be coupled with optimized electrode materials and tailored electrolyte/electrode ***,this review critically outlines electrolytes’limiting factors,including reduced ionic conductivity,large de-solvation energy,sluggish charge transfer,and slow Li-ion transportation across the electrolyte/electrode interphases,which affect the low-temperature performance of Li-metal *** theoretical derivations that explain the explicit influence of temperature on battery performance are presented to deepen *** improvement strategies from the aspects of electrolyte design and electrolyte/electrode interphase engineering are summarized and rigorously *** on future research are proposed to guide the ongoing exploration for better low-temperature Li-metal batteries.

关键词： Solid electrolyte interphase Li metal Low temperature Electrolyte design Batteries

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Ignition and Lean Blowout Characteristics of a Reverse-Flow Combustor for an Ultra-Compact Gas Turbine Engine

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Journal of Thermal Science 2024年第5期33卷 1897-1906页

作者： JIN Yi HUANG Yakun YAO Kanghong zhang kai WANG Yunbiao WANG Donghao College of Energy and Power Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China National Key Laboratory of Transient Physics Nanjing University of Science and TechnologyNanjing 210094China Low-carbon Aerospace Power Engineering Research Center of Ministry of Education Nanjing 210016China

The flame stability limit and propagation characteristics of a reverse-flow combustor without any flame-stabilized device were experimentally investigated under room temperature and *** results indicate that it is feasible to stabilize the flame in the recirculation zones constructed by the impact jet flow from the primary holes and dilution *** flame projected area is mainly distributed in the recirculation zone upstream of the primary holes,whose presence and absence mark the ignition and *** the ignition process,the growth rate and value of the flame projected area first increase and then decrease with the inlet velocity increasing from 9.4 m/s to 42.1 m/s.A rapid reduction followed by a slow reduction of ignition and lean blowout equivalence ratios is achieved by the increased inlet *** the non-reacting fluid structure in three sections was measured,and detailed velocity profiles were analyzed to improve the understanding of the flame stabilization *** results are conducive to the design of an ultra-compact combustor.

关键词： ultra-compact combustor gas turbine reverse-flow combustor ignition lean blowout

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Targeted multi-agent communication algorithm based on state control

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Defence Technology（防务技术） 2024年第1期31卷 544-556页

作者： Li-yang Zhao Tian-qing Chang Lei zhang Jie zhang kai-xuan Chu De-peng Kong Department of Weaponry and Control Army Academy of Armored ForcesBeijing100072China Unit 92942 Beijing100161China

As an important mechanism in multi-agent interaction,communication can make agents form complex team relationships rather than constitute a simple set of multiple independent ***,the existing communication schemes can bring much timing redundancy and irrelevant messages,which seriously affects their practical *** solve this problem,this paper proposes a targeted multiagent communication algorithm based on state control(SCTC).The SCTC uses a gating mechanism based on state control to reduce the timing redundancy of communication between agents and determines the interaction relationship between agents and the importance weight of a communication message through a series connection of hard-and self-attention mechanisms,realizing targeted communication message *** addition,by minimizing the difference between the fusion message generated from a real communication message of each agent and a fusion message generated from the buffered message,the correctness of the final action choice of the agent is *** evaluation using a challenging set of Star Craft II benchmarks indicates that the SCTC can significantly improve the learning performance and reduce the communication overhead between agents,thus ensuring better cooperation between agents.

关键词： Multi-agent deep reinforcement learning State control Targeted interaction Communication mechanism

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Theoretical and Experimental Study on the Performance of Hermetic Diaphragm Squeeze Film Dampers for Gas-Lubricated Bearings

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Chinese Journal of Mechanical Engineering 2024年第3期37卷 151-169页

作者： Jianwei Wang Haoxi zhang Shaocun Han Hang Li Peng Wang kai Feng State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China

Low damping characteristics have always been a key sticking points in the development of gas *** application of squeeze film dampers can significantly improve the damping performance of gas lubricated *** paper proposed a novel hermetic diaphragm squeeze film damper(HDSFD)for oil-free turbomachinery supported by gas lubricated *** types of HDSFDs with symmetrical structure were proposed for good damping *** considering the compressibility of the damper fluid,based on hydraulic fluid mechanics theory,a dynamic model of HDSFDs under medium is proposed,which successfully reflects the frequency dependence of force *** on the dynamic model,the effects of damper fluid viscosity,bulk modulus of damper fluid,thickness of damper fluid film and plunger thickness on the dynamic stiffness and damping of HDSFDs were *** experimental test rig was assembled and series of experimental studies on HDSFDs were *** damper fluid transverse flow is added to the existing HDSFD concept,which aims to make the dynamic force coefficients independent of *** the force coefficient is still frequency dependent,the damping coefficient at high frequency excitation with damper fluid supply twice as that without damper fluid *** results serve as a benchmark for the calibration of analytical tools under development.

关键词： Hermetic diaphragm squeeze film damper Compressibility Dynamic model Experimental studies

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PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma

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Genes & Diseases 2024年第4期11卷 340-352页

作者： Rui Liu Yi Liu Wenlu zhang Guiji zhang Zhirong zhang Luyi Huang Ni Tang kai Wang Key Laboratory of Molecular Biology for Infectious Diseases(Ministry of Education) Institute for Viral HepatitisDepartment of Infectious DiseasesThe Second Affiliated HospitalChongqing Medical UniversityChongqing 400016China Department of Clinical Laboratory Sichuan Clinical Research Center for CancerSichuan Cancer Hospital&InstituteSichuan Cancer CenterAffiliated Cancer Hospital of University of Electronic Science and Technology of ChinaChengduSichuan 610041China

Liver cancer stem cells were found to rely on glycolysis as the preferred metabolic *** carboxylase 1(PCK1),a gluconeogenic metabolic enzyme,is down-regulated in hepatocellular carcinoma and is closely related to poor *** onco-genesis and progression of tumors are closely related to cancer stem *** is not completely clear whether the PCK1 deficiency increases the stemness of hepatoma cells and promotes the oncogenesis of hepatocellular ***,the results showed that PCK1 inhibited the self-renewal property of hepatoma cells,reduced the mRNA level of cancer stem cell markers,and inhibited ***,PCK1 increased the sensitivity of hepatocellular carci-noma cells to ***,we found that PCK1 activated the Hippo pathway by enhancing the phosphorylation of YAP and inhibiting its nuclear *** reduced the stemness of hepatoma cells and promoted the pro-apoptotic effect of ***,combined treatment with verteporfin and sorafenib may be a potential anti-tumor strat-egy in hepatocellular carcinoma.

关键词： Cancer stem cells Chemoresistance Gluconeogenesis Hepatocellular carcinoma YAP

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City Network Evolution Characteristics of Smart Industry: Evidence from Yangtze River Delta, China

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Chinese Geographical Science 2024年第5期34卷 829-848页

作者： SHEN Lizhen zhong Zhaocheng CHEN Cheng zhang Shanqi ZHEN Feng School of Architecture and Urban Planning Nanjing UniversityNanjing 210093China Hefei Urban Planning&Design Institute Hefei 230041China

The dual-path model of industrial evolution and spatial progression has been widely acknowledged and incorporated into the strategic planning to promote the development of urban industries and regional ***,current research on inter-enter-prise city networks mainly focuses on the single sector of flows on all enterprise branches,such as product value chains and production factors,but neglects that of particular industry *** upon the new economic geography and city networks theory,this paper develops a methodological framework that focuses on the analysis of city network evolution characteristics of smart ***-larly,a conceptual model of smart industry enterprise-industry-city is proposed and then applied to a case study of smart industry in the Yangtze River Delta Region,*** enterprise supplier-customer data,a city network of smart industry is constructed and sub-sequently analyzed with the proposed *** indicate that the smart industry network in Yangtze River Delta Region exhibits a hierarchical structure and the expansion of the network presents a small-world network *** study not only makes a meth-odological contribution for revealing the industrial and spatial evolution path of the current smart industry,but also provides empirical support for the formulation of new economic development policies focused on smart industries,demonstrating the role of city clusters as carriers of regional synergistic development.

关键词： smart industry city networks social network analysis methodological framework Yangtze River Delta,China

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Application of the Conditional Nonlinear Local Lyapunov Exponent to Second-Kind Predictability

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Advances in Atmospheric Sciences 2024年第9期41卷 1769-1786页

作者： Ming zhang Ruiqiang DING Quanjia zhong Jianping LI Deyu LU State Key Laboratory of Earth Surface Processes and Resource Ecology(ESPRE)/Key Laboratory of Environmental Change and Natural Disasters of Chinese Ministry of EducationBeijing Normal UniversityBeijing 100875China Department of Ocean Science Hong Kong University of Science and TechnologyHong KongChina College of Oceanic and Atmospheric Sciences/Frontiers Science Center for Deep Ocean Multispheres and Earth System(DOMES)/Key Laboratory of Physical Oceanography Ministry of Education/Academy of the Future Ocean/Center for Ocean Carbon NeutralityOcean University of ChinaQingdao 266100China Laoshan Laboratory Qingdao 266237China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China College of Earth Science University of Chinese Academy of SciencesBeijing 100049China

In order to quantify the influence of external forcings on the predictability limit using observational data,the author introduced an algorithm of the conditional nonlinear local Lyapunov exponent(CNLLE)*** effectiveness of this algorithm is validated and compared with the nonlinear local Lyapunov exponent(NLLE)and signal-to-noise ratio methods using a coupled Lorenz *** results show that the CNLLE method is able to capture the slow error growth constrained by external forcings,therefore,it can quantify the predictability limit induced by the external *** this basis,a preliminary attempt was made to apply this method to measure the influence of ENSO on the predictability limit for both atmospheric and oceanic variable *** spatial distribution of the predictability limit induced by ENSO is similar to that arising from the initial conditions calculated by the NLLE *** similarity supports ENSO as the major predictable signal for weather and climate *** addition,a ratio of predictability limit(RPL)calculated by the CNLLE method to that calculated by the NLLE method was *** RPL larger than 1 indicates that the external forcings can significantly benefit the long-term predictability *** instance,ENSO can effectively extend the predictability limit arising from the initial conditions of sea surface temperature over the tropical Indian Ocean by approximately four months,as well as the predictability limit of sea level pressure over the eastern and western Pacific ***,the impact of ENSO on the geopotential height predictability limit is primarily confined to the troposphere.

关键词： conditional nonlinear local Lyapunov exponent second-kind predictability coupled Lorenz model ENSO

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Evolution of In783 alloy in microstructure and properties enduring different service times

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Rare Metals 2024年第1期43卷 334-341页

作者： zhong-Shuai Han Jin-Feng Du Jun Liang Zheng zhang School of Material Science and Engineering Beihang UniversityBeijing 100191China Shenhua Guohua(Beijing)Electric Power Research Institute Co. Ltd.Beijing 100025China

Impact, tensile, and fatigue tests were performed in In783 alloy serving 4000, 23,000 and 48,000 h. The microstructure was then analysed by optical microscopy(OM), scanning electron microscopy(SEM), and transmission electron microscopy(TEM) to probe the relationship between microstructure and properties. The results show that a new Ni_(5)Al_(3) phase is found, which grows gradually in β phase with serving time increasing,destroying the martensitic structure of the β phase, and degenerating the toughness of the β phase(approximately13.88% reduction). Therefore, the degradation of the βphase results in a sharp dropping of the resistance to stress accelerated grain boundary oxygen(SAGBO) during serving;thus, the intergranular fracture morphology degree increases with duration of service(almost 40% increase from the fractured surface). In addition, the strength of alloy will be gradually enhanced when the γ'phase becomes relatively bulky with serving time increasing due to considerable distortion of the dislocations as a result of the spacing of individual particles, in which any movement of the dislocation will have to overcome a larger number of obstacles per unit length.

关键词： In783 Microstructure Properties βphase Ni_(5)Al_(3)phase

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GATIS score for predicting the prognosis of rectal neuroendocrine neoplasms:A Chinese multicenter study of 12-year experience

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World Journal of Gastroenterology 2024年第28期30卷 3403-3417页

作者： Xin-Yu Zeng Ming zhong Guo-Le Lin Cheng-Guo Li Wei-zhong Jiang Wei zhang Li-Jian Xia Mao-Jun Di Hong-Xue Wu Xiao-Feng Liao Yue-Ming Sun Min-Hao Yu kai-Xiong Tao Yong Li Rui zhang Peng zhang Department of Gastrointestinal Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074Hubei ProvinceChina Department of Gastrointestinal Surgery Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of General Surgery Peking Union Medical College HospitalPeking Union Medical CollegeBeijing 100730China Department of Colorectal Surgery Fujian Medical UniversityFuzhou 350401Fujian ProvinceChina Department of Colorectal Surgery Changhai HospitalShanghai 200433China Department of Gastrointestinal Surgery The First Affiliated Hospital of Shandong First Medical UniversityJinan 250118Shandong ProvinceChina Department of Gastrointestinal Surgery Taihe HospitalHubei University of MedicineShiyan 442099Hubei ProvinceChina Department of Gastrointestinal Surgery I Section Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina Department of General Surgery Xiangyang Central HospitalAffiliated Hospital of Hubei University of Arts and ScienceXiangyang 441021Hubei ProvinceChina Department of Colorectal Surgery Jiangsu Province HospitalNanjing Medical UniversityNanjing 210029Jiangsu ProvinceChina Department of Gastrointestinal Surgery School of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of General Surgery Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080Guangdong ProvinceChina Department of Colorectal Surgery Liaoning Cancer HospitalShenyang 110042Liaoning ProvinceChina

BACKGROUND There is currently a shortage of accurate,efficient,and precise predictive instruments for rectal neuroendocrine neoplasms(NENs).AIM To develop a predictive model for individuals with rectal NENs(R-NENs)using data from a large *** Data from patients with primary R-NENs were retrospectively collected from 17 large-scale referral medical centers in *** forest and Cox proportional hazard models were used to identify the risk factors for overall survival and progression-free survival,and two nomograms were *** A total of 1408 patients with R-NENs were *** grade,T stage,tumor size,age,and a prognostic nutritional index were important risk factors for *** GATIS score was calculated based on these five *** overall survival prediction,the respective C-indexes in the training set were 0.915(95%confidence interval:0.866-0.964)for overall survival prediction and 0.908(95%confidence interval:0.872-0.944)for progression-free survival *** to decision curve analysis,net benefit of the GATIS score was higher than that of a single *** time-dependent area under the receiver operating characteristic curve showed that the predictive power of the GATIS score was higher than that of the TNM stage and pathological grade at all time *** The GATIS score had a good predictive effect on the prognosis of patients with R-NENs,with efficacy superior to that of the World Health Organization grade and TNM stage.

关键词： Rectal neuroendocrine neoplasm Nomogram Random forest Prognosis Overall survival Progression-free survival

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