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Array FBG sensing and 3D reconstruction of spacecraft configuration

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Optoelectronics Letters 2022年第4期18卷 193-199页

作者： jiang yue yan Jie ZHANG Lei jiang Mingshun LUO Yuxiang SUI Qingmei School of Control Science and Engineering Shandong UniversityJinan 250061China Shandong Institute of Space Electronic Technology Yantai 264003China

In this paper, a plate shape perception technique based on quasi-distributed fiber Bragg grating(FBG) array and space surface reconstruction algorithm is proposed. Firstly, in order to make curvature continuous, the bicubic plane interpolation algorithm is studied. Then, taking the simulated satellite bulkhead structure as the research object, we research the space surface reconstruction algorithm based on orthogonal curvature and coordinate transformation(translation and rotation). Finally, a four-sided fixed plate deformation monitoring system based on quasi-distributed FBG sensors network and surface reconstruction algorithm is built. Many experiments are conducted to verify the reliability and accuracy of the algorithm. The proposed algorithm provides a new method for three-dimensional reconstruction of spacecraft structure.

关键词： curvature algorithm sided

Expression of Dickkopf-related Protein 1 in Patients with Temporomandibular Osteoarthritis after Treatment with Hyaluronic Acid

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Current Medical Science 2020年第3期40卷 574-579页

作者： Sheng-jun jiang zhong-zhi JIN You-jian PENG Department of Stomatology Renmin Hospital of Wuhan UniversityWuhan430060China

We previously reported that the increased expression of Dickkopf-related protein 1(DKK1)is positively related to vascular endothelial growth factor in the synovial fluid from patients with temporomandibular joint disorders(TMDs).DKK1 is involved in angiogenic activities in the TMD synovium in vitro,but the expression of DKK1 after treatment of TMD-osteoarthritis(TMD-OA)with hyaluronic acid(HA)remains *** this study,we assessed the expression of DKK1 in the synovial fluid of TMD-OA patients before and after treatment with HA via enzyme-linked immunosorbent *** also investigated the role of DKK1 in TMD-OA via immunohistochemical *** relationship between the expression of DKK1 and the clinicopathological characteristics was determined by Pearson *** results showed that the expression of DKK1 was significantly decreased after treatment with *** analyses indicated that the expression of DKK1 in the TMD-OA samples was closely correlated with mouth opening and *** findings suggest that DKK1 could play an important role in the pathogenesis and treatment of *** of the pain by HA treatment may be correlated with the decreased expression of DKK1.

关键词： Dickkopf-related protein 1 temporomandibular joint disorders hyaluronic acid synovial fluid

Mining Design Pattern Use Scenarios and Related Design Pattern Pairs:A Case Study on Online Posts

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Journal of Computer Science & Technology 2020年第5期35卷 963-978页

作者： Dong Liu Zhi-Lei Ren zhong-Tian Long Guo-jun Gao He jiang School of Software Dalian University of TechnologyDalian 116024China Key Laboratory for Ubiquitous Network and Service Software of Liaoning Province Dalian 116000China DUT-RU International School of Information Science&Engineering at DUT Dalian University of Technology Dalian 116620China

In common design pattern collections,e.g.,design pattern books,design patterns are documented with templates that consist of multiple attributes,such as intent,structure,and sample *** adapt to modern developers,the depictions of design patterns,especially some specific attributes,should advance with the current programming technologies,for example,“known uses”,which exemplifies the use scenarios of design patterns in practice,and“related patterns”,which describes the relatedness between a design pattern and the others within a ***,it is not easy to update the contents of these attributes manually due to the diversity of the programming *** address this problem,in this work,we conducted a case study to mine design pattern use scenarios and related design pattern pairs from Stack Overflow posts to enrich the two *** first extracted the question posts relevant to each design pattern by identifying the design pattern ***,the topics of the posts were discovered by applying topic modeling ***,by analyzing the topics specified for each design pattern,we detected 195 design pattern use scenarios and 70 related design pattern pairs,involving 61 design patterns *** findings are associated with a variety of popular software frameworks and programming *** could complement the existing design pattern collections and help developers better acknowledge the usage and relatedness of design patterns in today's programming practice.

关键词： design pattern software documentation Stack Overflow topic model

Design and semisynthesis of oleanolic acid derivatives as VEGF inhibitors:Inhibition of VEGF-induced proliferation,angiogenesis,and VEGFR2 activation in HUVECs

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Chinese Journal of Natural Medicines 2022年第3期20卷 229-240页

作者： MENG Ning XIE Hong-Xu HOU Jia-Rong CHEN yan-Bin WU Meng-jun GUO yue-Wei jiang Cheng-Shi School of Biological Science and Technology University of JinanJinan 250022China State Key Laboratory ofDrug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China

Angiogenesis inhibitors targeting the VEGF signaling pathway are developed into drugs for the treatment of vaious diseases,such as cancer,rheumatoid arthritis,and age-related macular *** studies have revealed that oleanolic acid(OA),a natural pentacyclic triterpenoid,inhibited the VEGF/VEGFR2 signaling pathway and angiogenesis in HUVECs,which may represent an attractive VEGF *** this paper,rational structural modification towards OA was performed in order to improve its inhibitory effects aganist VEGF and anti-angiogenesis *** a result,a series of novel OA derivatives,possessingα,β-unsat-urated ketone system in ring A and amide functional group at C-28,were prepared and evaluated for cytotoxicity and their ability to inhibit VEGF-induced abnormal proliferation of *** results showed that two promising derivatives,OA-1 and OA-16,exhibited no in vitro cytotoxicity against HUVECs but showed more potent inhibitory activity against VEGF-induced proliferation and angiogenesis in HUVECs,compared with *** results of Western blot indicated that OA-1 and OA-16 inhibited VEGF-induced VE-GFR2 ***,small interfering RNA experiments were performed to confirm that both compounds inhibited VEGF-induced angiogenesis via ***,the present study resulted in the discovery of new promising OA-inspired VEGF inhibitors,which can serve as potential lead compounds for the treatment of angiogenesis-related diseases.

关键词： Oleanolic acid Structural modification VEGF inhibitor VEGFR2 Angiogenesis

Spectral sensitivity of the compound eyes of Anomala corpulenta motschulsky(Coleoptera:Scarabaeoidea)

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Journal of Integrative Agriculture 2015年第4期14卷 706-713页

作者： jiang yue-li Guo Yu-yuan Wu Yu-qing Li Tong Duan Yun Miao Jin Gong zhong-jun Huang Zhi-juan College of Plant Protection Northwest A&F University Key Laboratory of Crop Pest Control of Henan Province/Institute of Plant Protection Henan Academy of Agricultural Sciences State Key Laboratory for the Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural Sciences

The scarab beetle, Anomala corpulenta Motschulsky（Coleoptera： Scarabaeoidea）, is a widespread and destructive pest in China. Vision is one of the most important means of acquiring information about the external environment. In order to contribute to the understanding of the perception of visual stimuli in this species, the light sensitivity and spectral responses of the scarab beetle, A. corpulenta, were measured by using an electroretinogram（ERG） technique. In total, 14 monochromatic light intensities, between 340 and 605 nm, were applied to the compound eyes of A. corpulenta under varying levels of adaptation to dark and light conditions. The results showed that all light stimuli induced an ERG response, with varied amplitudes. The spectral sensitivity curve of dark-adapted eyes showed one major peak（~400 nm; near-ultraviolet）, a secondary peak（from 498 to 562 nm; yellow-green） and the third peakat 460 nm. By contrast, in light-adapted eyes, only a near-UV peak was observed. From these results, we conclude that the compound eye of A. corpulenta is likely to have at least three spectral types of photoreceptor. Significance of differences were also recorded in the responses of male and female compound eyes, as well as diurnally and nocturnally. The amplitude of ERG in response to white-light stimuli varied with the light intensity： The stronger the luminance, the higher the ERG value. This suggests that the compound eye of A. corpulenta adapts quickly to changing light conditions, enabling A. corpulenta to maintain nocturnal activities.

关键词： Anomala corpulenta electroretinogram insect vision spectral sensitivity light intensity

3-D Fracture Network Modelling in Hydropower Engineering Based on Optimal Monte Carlo Simulation

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Transactions of Tianjin University 2017年第4期23卷 351-359页

作者： Pan yue Denghua zhong Fugen yan Han Wu Yichi Zhang State Key Laboratory of Hydraulic Engineering Simulation and Safety School of Civil EngineeringTianjin University Changjiang Institute of Survey PlanningDesign and Research

Effectively and accurately modelling the spatial relation of fracture surfaces is crucial in the design and construction of large hydropower dams having a complex underlying geology. However, fracture surfaces are randomly formed and vary greatly with respect to their spatial distribution, which makes the construction of accurate 3-D models challenging. In this study, we use an optimal Monte Carlo simulation and dynamic conditioning to construct a fracture network model. We found the optimal Monte Carlo simulation to effectively reduce the error associated with the Monte Carlo method and use dynamic conditioning to ensure the consistency of the model with the actual distribution of fractures on the excavation faces and outcrops. We applied this novel approach to a hydropower station on the Jinshajiang River, China. The simulation results matched the real sampled values well, confirming that the model is capable of effectively and accurately simulating the spatial relations in a fracture network. © 2017, Tianjin University and Springer-Verlag Berlin Heidelberg.

关键词： Fracture Hydroelectric power Hydroelectric power plants Intelligent systems Underground structures

Editorial for rare metals, special issue on advanced thermoelectric materials

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Rare Metals 2018年第4期37卷 257-258页

作者： yan-zhong Pei Xiao-Yuan Zhou Tie-jun Zhu School of Materials Science and Engineering Tongji University College of Physics Chongqing University School of Materials Science and Engineering Zhejiang University

As a clean energy technology to combat the global energy dilemma and the environmental problems, thermoelectrics that enable a direct conversion between heat and electricity have attracted increasing attention in recent decades. This solid-state, vibrationless technology has long been used for powering the spacecrafts of several deep-space missions and has limited commercial use in niche market, but these are now actively considered for a variety of new applications, such as the conversion of automobile exhaust heat into electricity. Meanwhile, materials research flourishes with the knowledge that significantly improves the thermoelectric efficiency for even more applications. This motivates Rare Metals to have a special issue focusing on thermoelectrics.

关键词： Editorial for rare metals special issue on advanced thermoelectric materials

Reduction in Microsegregation in Al-Cu Alloy by Alternating Magnetic Field

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Acta Metallurgica Sinica(English Letters) 2020年第2期33卷 267-274页

作者： Sheng-Ya He Chuan-jun Li Tong-jun Zhan Wei-Dong Xuan jiang Wang zhong-Ming Ren State Key Laboratory of Advanced Special Steel and School of Materials Science and Engineering Shanghai UniversityShanghai 200444China Helmholtz-Zentrum Dresden-Rossendorf(HZDR) 01328 DresdenGermany

The microsegregation behavior of the Al-4.5 wt%Cu alloy solidified at different cooling rates under the alternating magnetic field(AMF) was *** experimental results showed that the amount of non-equilibrium eutectics in the interdendritic region decreased upon applying the AMF at the same cooling *** change in microsegregation could be explained quantificationally by the modifications of dendritic coarsening,solid-state back diffusion and convection in the *** enhanced diffusivity in the solid owing to the AMF was beneficial for the improvement in microsegregation compared to the cases without an *** contrast,the enhanced dendritic coarsening and forced convection in the AMF were found to aggravate the microsegregation *** the contributions of the changes in above factors,an increase in solid diffusivity was found to be primarily responsible for the reduced microsegregation in the *** addition,the microsegregation in the AMF was modeled using the analytical model developed by *** calculated and experimental results were in reasonable agreement.

关键词： Microsegregation Solidification Alternating magnetic field Diffusion Coarsening Convection

Modified Bfat-1 gene and its biological verification in mice by hydrodynamic tail vein injection

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Journal of Integrative Agriculture 2016年第6期15卷 1330-1337页

作者： GAO Xue DU Xin-hua ZHANG Lu-pei CHEN yan GAO Hui-jiang XU Shang-zhong LI jun-ya Key Laboratory for Farm Animal Genetic Resources and Utilization Ministry of AgricultureInstitute of Animal Science Chinese Academy of Agricultural Sciences State Key Laboratory of Agro-Biotechnology China Agricultural University

Omega-3 polyunsaturated fatty acids （w-3 PUFAs） are essential components required for normal cellular function and have been shown to have important therapeutic and nutritional benefits in humans. But humans or mammals cannot naturally produce w-3 PUFAs, due to the lack of the co-3 fatty acid desaturase gene （fat-1 gene）. Previously, fat-1 gene has been cloned from Caenorhabditis elegans and transferred into mice, pigs and sheep, but not yet into beef cattle. We attempt to transfer it into beef cattle. The object of this paper is to edit the fat-1 gene from C. elegans to express more efficiently in beef cattle and verify its biological function in mice model. As a result, the fat-1 gene from C. elegans was modified by synonymous codon usage and named it Bfat-l. We have demonstrated that degree of codon bias of Brat-1 gene was in- creased in beef cattle. Moreover, Bfat-1 gene could be transiently expressed in mouse liver and muscle, the w-6/co-3 PUFAs ratio of 18 and 20 carbon was decreased significantly in liver （P〈0.05）, and the ratio of 20 carbon decreased significantly in muscle 24 and 72 h after injection （P〈0.05）. This confirms that the Bfat-1 gene modification was successful, and the protein encoded was able to catalyze the conversion of w-6 PUFAs to e0-3 PUFAs.

关键词： beef cattle codon bias modified Brat-l hydrodynamic tail vein injection mice