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Functional divergences of natural variations of TaNAM-A1 in controlling leaf senescence during wheat grain filling

Journal of Integrative Plant Biology 2024年第6期66卷 1242-1260页

作者： Longxi Zhou Guowei Chang Chuncai Shen Wan Teng Xue He Xueqiang Zhao Yanfu Jing zhixiong huang Yiping Tong Key Laboratory of Seed Innovation Institute of Genetics and Developmental SciencesChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China The Innovative Academy of Seed Design Chinese Academy of SciencesBeijing 100101China

Leaf senescence is an essential physiological process related to grain yield potential and nutritional *** leaf duration(GLD)after anthesis directly reflects the leaf senescence process and exhibits large genotypic differences in common wheat;however,the underlying gene regulatory mechanism is still ***,we identified TaNAM-A1 as the causal gene of the major loci q GLD-6A for GLD during grain filling by map-based *** assays and TILLING mutant analyses demonstrated that TaNAM-A1 played a critical role in regulating leaf senescence,and also affected spike length and grain ***,the functional divergences among the three haplotypes of TaNAM-A1 were systematically *** varieties with TaNAM-A1d(containing two mutations in the coding DNA sequence of TaNAM-A1)exhibited a longer GLD and superior yield-related traits compared to those with the wild type *** three haplotypes were functional in activating the expression of genes involved in macromolecule degradation and mineral nutrient remobilization,with TaNAM-A1a showing the strongest activity and TaNAM-A1d the ***-A1 also modulated the expression of the senescencerelated transcription factors TaNAC-S-7A and ***016-3A enhanced the transcriptional activation ability of TaNAM-A1a by protein–protein interaction,thereby promoting the senescence *** study offers new insights into the fine-tuning of the leaf functional period and grain yield formation for wheat breeding under various geographical climatic conditions.

关键词： allelic variation leaf senescence map-based cloning TaNAM-A1 transcription factor Triticum aestivum

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2020—2023年宜昌市中心人民医院新型抗肿瘤药物使用情况分析

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现代药物与临床 2024年第5期39卷 1319-1326页

作者：王燕黄志雄三峡大学第一临床医学院宜昌市中心人民医院药学部湖北宜昌443003

目的分析2020—2023年宜昌市中心人民医院新型抗肿瘤药物的使用情况和发展趋势,为该类药物的临床合理使用和规范化管理提供参考。方法收集宜昌市中心人民医院2020年1月1日—2023年12月31日新型抗肿瘤药物的相关用药信息,对品种数、销售... 详细信息

目的分析2020—2023年宜昌市中心人民医院新型抗肿瘤药物的使用情况和发展趋势,为该类药物的临床合理使用和规范化管理提供参考。方法收集宜昌市中心人民医院2020年1月1日—2023年12月31日新型抗肿瘤药物的相关用药信息,对品种数、销售金额、用药频度(DDDs)、限定日费用(DDC)、药品排序比(B/A)等指标进行回顾性统计分析。结果2020—2023年新型抗肿瘤药物的品种数呈波动态势,总销售金额和总DDDs逐年增长,30种药物的DDC下降。贝伐珠单抗、奥希替尼和曲妥珠单抗的销售金额均位居前3位。信迪利单抗的DDDs增长速度最快,在2023年排名升至第1位,DDC值从2020年270.76降至2023年的102.86,连续4年B/A≥1。奥希替尼和阿美替尼的临床使用频率明显增加,2023年DDDs分别排名第2、3位。伊马替尼和吉非替尼使用频率较高、DDC值低,B/A在4年内均大于2,同步性好,利用度高。结论宜昌市中心人民医院新型抗肿瘤药物使用量逐渐增加,药品价格下降,符合国家政策要求及肿瘤治疗的发展趋势。

关键词：新型抗肿瘤药物销售金额用药频度限定日费用贝伐珠单抗奥希替尼曲妥珠单抗信迪利单抗

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我国职业教育产教融合政策变迁历程与动力机制——间断-均衡理论视角

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高校教育管理 2024年第5期18卷 74-86页

作者：张茜许祥云黄志雄南昌大学公共政策与管理学院江西南昌330031 重庆公共运输职业学院公共管理学院重庆402284

产教融合是职业教育实现高质量发展的关键。以间断-均衡理论为基础,借助政策范式理论,本研究构建职业教育产教融合政策变迁分析框架,运用内容分析法对新中国成立以来职业教育产教融合政策变迁逻辑进行客观梳理与系统剖析。研究验证并拓... 详细信息

产教融合是职业教育实现高质量发展的关键。以间断-均衡理论为基础,借助政策范式理论,本研究构建职业教育产教融合政策变迁分析框架,运用内容分析法对新中国成立以来职业教育产教融合政策变迁逻辑进行客观梳理与系统剖析。研究验证并拓展了间断-均衡理论的适用性,发现职业教育产教融合政策呈现渐进性均衡和突发性间断相结合的变迁样态,具有非线性发展特征。制度环境和价值理念是推动政策变迁的主要动力,焦点事件通过影响决策者注意力为政策变迁开启“机会之窗”。强化顶层设计与政策供给、建立开放包容的政策场域、完善政策试点与保障机制是推动我国职业教育产教融合高质量发展的应然路径。

关键词：职业教育产教融合政策变迁间断-均衡理论制度环境价值理念焦点事件

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局域芯片分布特征辨识及自适应变步长扫描与匹配

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计算机集成制造系统 2024年第4期30卷 1273-1285页

作者：吴涛周意黄智雄叶玮琳吴福培李斌汕头大学智能制造技术教育部重点实验室广东汕头515063 华中科技大学机械科学与工程学院湖北武汉430074

为解决LED芯片检测与分选中的漏扫、匹配错误等关键问题,提出自适应变步长扫描方法。该方法对当前局域分布特性进行分析,利用晶圆片局部形变的连续性与保持性对邻近区域芯片分布进行预测,实施步长调整。在检测端,提出基于8邻域位置模型... 详细信息

为解决LED芯片检测与分选中的漏扫、匹配错误等关键问题,提出自适应变步长扫描方法。该方法对当前局域分布特性进行分析,利用晶圆片局部形变的连续性与保持性对邻近区域芯片分布进行预测,实施步长调整。在检测端,提出基于8邻域位置模型的区域芯片分布特征表征与描述方法,确立自适应步长调整策略,建立物理地址映射视图以及归一化逻辑视图。在分选端,利用已知物理地址映射图和归一化逻辑视图,对扫描区域、步长与路径进行规划,在遍历芯片的同时,实现芯片匹配。实测表明,相比冗余方法,该方法能够以低于4%的冗余率,实现漏扫率低于0.5%,提升扫描效率近23%。由于只针对有意义的芯片进行查找,可实现接近100%的匹配率,显著改善了算法效率和抗干扰能力。

关键词：晶圆片映射视图逻辑归一化主动遍历位置关系索引匹配

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违约金过分高于造成的损失的判定

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人民司法 2024年第5期 46-48页

作者：黄志雄福建省诏安县人民法院

【裁判要旨】“约定的违约金过分高于造成的损失,当事人可以请求人民法院或者仲裁机构予以适当减少。”司法实践中,如何判定约定的违约金,如何予以适当调整,法律均未进一步明确。违约金的调整应以法定、合理性为原则,综合考虑当事人过... 详细信息

【裁判要旨】“约定的违约金过分高于造成的损失,当事人可以请求人民法院或者仲裁机构予以适当减少。”司法实践中,如何判定约定的违约金,如何予以适当调整,法律均未进一步明确。违约金的调整应以法定、合理性为原则,综合考虑当事人过错情况、案件的不同性质和合同履行情况确定。

关键词：仲裁机构合同履行裁判要旨违约金过错司法实践人民法院合理性

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Thickening and Rheological Properties of Crystalline Polyester Used in Low Pressure Sheet Molding Compounds

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Chinese Journal of Mechanical Engineering 2011年第3期24卷 452-459页

作者： LI Jian huang zhixiong ZHANG Kai Department of Materials Engineering Hubei University of Automotive Technology Shiyan 442002 China School of Materials Science andEngineering Wuhan University of Technology Wuhan 430070 China Wuhan Institute of Marine Electric Propulsion CSIC712 Wuhan 430064 China

Low pressure sheet molding compound （LPMC,1.0-3.0 MPa,95-103 ℃） is a new kind of thermosetting material with crystalline polyester as a physical *** is different from conventional SMC using an earth oxide thickening agent （***） as chemical thickenner,it relies on the physical thickening of crystalline *** polyester resin is the key material to mold LPMC *** there was no report about the thickening mechanism of crystalline polyester in *** this article,crystalline polyester resins,whose melting points were between 45 ℃ and 89 ℃,were synthesized by a two-step *** melt points of crystalline polyesters are controlled by regulating the mol ratio of the two glycols and the two *** by means of varying the content of crystalline polyester resin,the thickening effect on resin paste is *** addition,the thickening mechanism of crystalline polyester in LPMC was investigated by FTIR and DSC *** effects of the diameters and viscosity of crystalline polyester on the rheological property and fiber distribution of LPMC sheets were studied,*** show that the thickening effect is excellent when the weight content of crystalline polyester resin is 3%.And there exists three kinds of functions acting in the process of thickening：swelling,hydrogen bonds and induction *** the preparing process of resin paste in LPMC,the temperature of resin paste must be kept at 90 ℃.In addition,crystalline polyester make LPMC have a perfect fluid *** the viscosity of LPMC sheet is beyond 1 kPa s,the fiber orientation is not *** when the viscosity of LPMC sheet is about 500 Pa s,the fiber shows a certain degree of *** the study of physical and chemical thickening mechanism of crystalline polyester and the rheological discipline of LPMC sheets in the hot mould will provide the researchers and enterprises with theory guidance.

关键词： low pressure low pressure sheet molding compound (LPMC) thickening mechanism rheological property fiber distribution

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Application of Multi-agent Particle Swarm Algorithm in Distribution Network Reconfiguration

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Chinese Journal of Electronics 2016年第6期25卷 1179-1185页

作者： SHU Dasong huang zhixiong LI Junye ZOU Xiaoyang Central South University Hunan Radio and TV University

An improved algorithm based on Multiagent particle swarm(MAS) is proposed to solve the distribution network reconfiguration problem in this *** approach is a combination of the learning, competition and cooperation mechanism of multi-agent technology and the strategies of Particle swarm optimization(PSO) algorithm. Using the Von Neumann topology structure in PSO algorithm, each particle represents an agent; each agent not only competes and cooperates with its neighborhood,but also absorbs the evolutionary mechanism of PSO algorithm, so as to share the information with the agent of global optimal. The rules of particle renovating reduce unfeasible solution in the process of particle renovating,and it is able to converge to global optimal accurately and quickly. Test on the IEEE 16-node, 32-node and 69-node system shows both a rapid convergence and a good robustness of this proposed approach.

关键词： Multi-agent system Particle swarm optimization Von Neumann topological structure Distribution network reconfiguration

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Microstructure and Ferroelectric Properties of (Bi_(0.9)Ho_(0.1))_(3.999)Ti_(2.997)V_(0.003)O_(12) Thin Films Prepared by Sol-gel Method for Nonvolatile Memory

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Journal of Materials Science & Technology 2010年第8期26卷 679-681页

作者： Chengju Fu zhixiong huang Jie Li Dongyun Guo School of Materials Science and Engineering Wuhan University of Technology Wuhan 430070 China School of Mechanical Engineering Chongqing University of Science and Technology Chongqing 400042 China

The （Bi0.9Ho0.1）3.999Ti2.997V0.003012 （BHTV） films have been prepared on Pt/Ti/SiO2/Si substrates by solgel method. The microstructure and ferroelectric properties of the BHTV films were investigated. The BHTV films show a single phase of Bi-layered Aurivillius structure and dense microstructure. The Ho3＋/V5＋ cosubstitution can effectively improve the ferroelectric properties. The BHTV film exhibits good ferroelectric properties with 2Pr of 47.6℃/cm2, 2Ec of 265 kV/cm （at applied field of 420 kV/cm）, dielectric constant of 305, dielectric loss of 0.031 （at 1 MHz）, good insulting behavior, as well as the fatigue-free behavior.

关键词： (Bi0.9Ho0.1)3.999Ti2.997V0.003O12 thin films Sol-gel method Co-substitution Ferroelectric properties Dielectric properties

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Acoustic emission detection of slag performance in coal gasifiers

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Chinese Journal of Chemical Engineering 2020年第8期28卷 2200-2207页

作者： Zhengliang huang Peng Zhang Yao Yang Jingyuan Sun JingdaiWang Yongrong Yang Chenghao huang zhixiong huang College of Chemical and Biological Engineering Zhejiang UniversityZhejiang Provincial Key Laboratory of Advanced Chemical Engineering Manufacture TechnologyHangzhou 310027China State Key Laboratory of Chemical Engineering Hangzhou 310027China Sinopec Group Anqing BranchAnqing 246000China

This work first investigated the detection of slags,slag pool liquid level,and slag accumulation height in laboratory scale based on acoustic emission(AE)detection,and further tried the feasibility of this method in an industrial scale coal *** show that the energy and variance of acoustic signals can realize the accurate detection of large slag(criterion:E>1.5 E0,S>1.2 S0),and the average relative error is only 0.28%.The acoustic energy in the frequency range of 20–40 k Hz is defined as the characteristic energy,which can realize the accurate detection of slag accumulation height and slag pool liquid level,and the average relative error is only 3.94%.Furthermore,AE detection also realize accurate detection of large slag in an industrial scale gasifier and the acoustic signals at slag screen can be used to realize the early warning of the slag collapse(5 h earlier).

关键词： Acoustic emission(AE)detection Slag pool liquid level Slag accumulation height Early warning

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Influence of Annealing Time on the Microstructure and Properties of Pb(Zr_(0.53)Ti_(0.47))O_3 Thin Films

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Journal of Wuhan University of Technology(Materials Science) 2012年第1期27卷 88-91页

作者： huang Ling MAO Wei huang zhixiong SHI Minxian MEI Qinlin School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430070China

The PZT thin films were prepared on （111）- Pt/Ti/SiO2/Si substrates by sol-gel method, and lead acetate [Pb（CH3COO）2], zirconium nitrate [Zr（NO3）4] were used as raw materials. The X-ray diffractometer （XRD） and scanning electron microscopy （SEM） were used to characterize the phase structure and surface morphology of the films annealed at 650 ~C but with different holding time. Ferroelectric and dielectric properties of the films were measured by the ferroelectric tester and the precision impedance analyzer, respectively. The PZT thin films were constructed with epoxy resin as a composite structure, and the damping properties of the composite were tested by dynamic mechanical analyzer （DMA）. The results show that the films annealed for 90 minutes present a dense and compact crystal arrangement on the surface; moreover, the films also achieve their best electric quality. At the same time, the largest damping loss factor of the composite constructed with the 90 mins-annealed film shows peak value of 0.9, hi^her than the pure epoxy resin.

关键词： sol-gel method Pb(Zr0.53Ti0.47)O3 thin film surface feature ferroelectric and dielectricproperty damping property

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