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自体髂骨移植联合钛板胸骨重建一例

中国胸心血管外科临床杂志 2024年第2期31卷 329-332页

作者：杨博李斌蒋鹏张少博任美玉苏志鹏兰州大学第二医院胸外科兰州大学第二临床医学院兰州730030

胸骨是胸廓的枢纽性成分,上部和两侧分别与锁骨及肋骨相连,在保护胸壁稳定性方面发挥重要作用。胸骨切除通常会产生大的节段性胸壁缺损,导致胸壁漂浮,必须进行胸骨重建。本文报道1例62岁胸腺鳞状细胞癌伴胸骨转移男性患者,完善相关检查... 详细信息

胸骨是胸廓的枢纽性成分,上部和两侧分别与锁骨及肋骨相连,在保护胸壁稳定性方面发挥重要作用。胸骨切除通常会产生大的节段性胸壁缺损,导致胸壁漂浮,必须进行胸骨重建。本文报道1例62岁胸腺鳞状细胞癌伴胸骨转移男性患者,完善相关检查,排除手术禁忌后行胸腺切除、胸骨肿瘤切除并同期行自体髂骨移植联合钛板胸骨重建术。术后随访6个月,患者呼吸运动功能正常,胸廓外观良好。

关键词：胸骨重建自体髂骨移植钛板病例报告

茶枝柑与不同品种温州蜜柑果皮的非靶向代谢组学比较与分析

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食品科学 2024年第14期45卷 133-141页

作者：王雪潘兆平陈嘉序郝丹丹苏志鹏马双双肖佳豪付复华湖南大学生物学院隆平分院湖南长沙410125 湖南省农业科学院农产品加工研究所湖南长沙410125

分析比较不同品种温州蜜柑与茶枝柑果皮的代谢组学差异,为温州蜜柑果皮的开发利用提供理论基础和科学依据。利用超高效液相色谱-串联质谱对茶枝柑与3个品种温州蜜柑的化学成分进行测定及分析,利用主成分分析、正交偏最小二乘判别分析和... 详细信息

分析比较不同品种温州蜜柑与茶枝柑果皮的代谢组学差异,为温州蜜柑果皮的开发利用提供理论基础和科学依据。利用超高效液相色谱-串联质谱对茶枝柑与3个品种温州蜜柑的化学成分进行测定及分析,利用主成分分析、正交偏最小二乘判别分析和聚类分析等多元统计方法对代谢组数据进行比较分析,筛选差异代谢物。通过数据库对比,茶枝柑(CZG)与油良(YL)、南柑20(NG)、宫川(GC)间分别鉴定出790、796、818个代谢物,其中有机氧化合物、黄酮类、羧酸类及其衍生物占比最高,主要参与黄酮和黄酮醇生物合成、黄酮类生物合成、异黄酮生物合成、α-亚麻酸代谢和苯丙氨酯生物合成等代谢途径;根据变量投影重要性值>1且P<0.05,对差异代谢物进行筛选,得到稳定、可靠的差异代谢物,结果表明,茶枝柑与温州蜜柑间共筛选出11类、43种差异代谢物,占比较多的为黄酮类、氨基酸类和嘌呤核苷类化合物,温州蜜柑中黄酮类化合物多为上调,如5,6,7,8,3’,4’,5’-七甲氧基黄酮、槲皮素、柚皮苷、山柰酚和柚皮素等,可作为潜在的标志物区分茶枝柑与温州蜜柑,同时表明温州蜜柑黄酮类化合物含量更具优势,可作为高生物活性的陈皮基原药材,推动柑橘产业发展,为陈皮产品的开发利用及原料选材提供参考依据。

关键词：茶枝柑温州蜜柑非靶向代谢组学差异代谢物

Construction of triblock copolymer-gold nanorod composites for fluorescence resonance energy transfer via pH-sensitive allosteric

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Chinese Chemical Letters 2020年第12期31卷 3131-3134页

作者： Li Zeng zhipeng su Xingyi Li Shuai Shi Institute of Biomedical Engineering School of Ophthalmology&Optometry and Eye HospitalWenzhou Medical UniversityWenzhou 325027China Department of Neurosurgery First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000China

To explore the effects of microenvironmental adjustments on fluorescence,a pH-sensitive nanocomposite system based on fluorescence resonance energy transfer(FRET)was *** model system included a modified triblock copolymer(polyhistidine-b-polyethylene glycol-b-polycaprolactone)and gold nanoparticles.A near-infrared dye was used as the donor,and spectrally matched gold nanorods,attached after C-terminus modification with α-lipoic acid,were used as the receptor to realize control of the FRET effect over the fluorescence intensity for two polymer configurational changes(i.e.,"folded"and"stretched"states)in response to *** synthesis and characterization,we investigated the self-assembly behavior of the *** by quartz crystal microbalance revealed the pH sensitivity of the polymer,which exhibited"folding"and"stretching"states with changes in pH,providing a structural basis for the FRET *** spectrophotometry investigations also revealed the regulatory impact of the assembled system on fluorescence.

关键词： Fluorescence resonance energy transfer pH response Self-assembled nanoparticle Au nanorod Block copolymer

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钛合金微槽超声螺线辅助铣磨加工试验研究

机械工程学报 2024年第9期60卷 5-12页

作者：苏志朋梁志强李娟王飞魏正义刘月红金惟薇马悦殷振王西彬北京理工大学机械与车辆学院北京100081 内蒙古北方重工业集团有限公司包头014030 苏州科技大学机械工程学院苏州215009

微铣削是实现航空微小零件精密加工的主要方法,但是受尺寸效应影响,使用该工艺加工钛合金等塑性高且强度大的材料时,易产生严重的切削变形以及毛刺等缺陷,影响微小零件加工质量。针对钛合金微槽加工过程中出现塑性变形大以及毛刺损伤严... 详细信息

微铣削是实现航空微小零件精密加工的主要方法,但是受尺寸效应影响,使用该工艺加工钛合金等塑性高且强度大的材料时,易产生严重的切削变形以及毛刺等缺陷,影响微小零件加工质量。针对钛合金微槽加工过程中出现塑性变形大以及毛刺损伤严重的问题,提出超声螺线辅助铣磨加工方法,将平面加工轨迹转变为三维螺线,进而实现微铣磨工具的端面和圆柱面与工件周期性分离,降低微铣磨力,改善微槽加工质量。开展超声辅助钛合金微槽铣磨加工仿真与试验研究,对比分析不同超声振动方式对微槽毛刺尺寸、表面质量、分形维数以及微铣磨力的影响,结果表明,相比无超声辅助、纵扭超声辅助以及切向超声辅助加工方法,超声螺线辅助加工得到毛刺尺寸最小,表面粗糙度最低,分形维数最大,微铣磨力最小。钛合金微槽加工质量得到了提高。验证了超声螺线辅助加工方法在钛合金微槽加工中的优势。

关键词：超声振动微铣削微磨削聚晶金刚石工具钛合金

微咸水与沼液一体化灌溉对设施番茄干物质累积和产量品质的影响

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灌溉排水学报 2024年第9期43卷 1-11页

作者：郑健刘俊彦宿智鹏王燕兰州理工大学能源与动力工程学院兰州730050 甘肃省太阳能与生物质互补多联供系统重点实验室兰州730050 西北低碳城镇支撑技术省部共建协同创新中心兰州730050

【目的】探明微咸水与沼液一体化灌溉对设施番茄植株干物质累积、果实产量及品质的影响,获得适宜番茄生长发育的微咸水矿化度阈值。【方法】以设施番茄为研究对象,于2022年和2023年开展了两季大田试验,在番茄3个生育期(苗期、开花坐果... 详细信息

【目的】探明微咸水与沼液一体化灌溉对设施番茄植株干物质累积、果实产量及品质的影响,获得适宜番茄生长发育的微咸水矿化度阈值。【方法】以设施番茄为研究对象,于2022年和2023年开展了两季大田试验,在番茄3个生育期(苗期、开花坐果期、成熟期)设置3个灌溉水矿化度(2、3、5 g/L),探求番茄干物质累积、产量、灌溉水利用效率、果实离子量和品质的响应规律,并采用主成分分析法和组合评价法分别对番茄果实品质及综合效益进行评价。【结果】苗期和开花坐果期使用5 g/L的微咸水与沼液一体化灌溉会抑制番茄各部位干物质量的增加;微咸水与沼液一体化灌溉均会降低番茄最终的产量,其降低主要是通过减少番茄单果质量来实现的,而对单株坐果数影响并不显著。但基于主成分分析法的番茄果实综合品质得分均有所提高;T4处理(苗期2g/L、开花坐果期3 g/L、成熟期5 g/L)番茄综合生产效益得分最高;各处理在一定程度上均降低了番茄果实对Na^(+)、Ca^(2+)的积累。【结论】基于组合评价法的番茄综合效益评价结果表明,在淡水资源紧缺微咸水资源丰富的地区,建议在番茄苗期使用2 g/L、开花坐果期使用3 g/L、成熟期使用5 g/L的微咸水与沼液一体化灌溉模式。

关键词：微咸水沼液设施番茄干物质累积产量品质

基于CEEMDAN和BiLSTM-AM的超短期风速预测方法

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电测与仪表 2024年第9期61卷 77-84页

作者：尹元亚潘文虎赵文广苏志朋韩屹吴红斌国网安徽省电力有限公司芜湖供电公司安徽芜湖241000 国网安徽省电力有限公司电力科学研究院合肥230601 合肥工业大学电气与自动化工程学院合肥230009

精准的风速预测结果可以推进风电的高效消纳以及增强新型电力系统的安全稳定性。为进一步挖掘风速序列的非线性特征,提升风速预测精度,提出了一种基于CEEMDAN与BiLSTM-AM的超短期风速预测方法。针对风速的随机波动性,采用自适应噪声完... 详细信息

精准的风速预测结果可以推进风电的高效消纳以及增强新型电力系统的安全稳定性。为进一步挖掘风速序列的非线性特征,提升风速预测精度,提出了一种基于CEEMDAN与BiLSTM-AM的超短期风速预测方法。针对风速的随机波动性,采用自适应噪声完备集合经验模态分解(complete ensemble empirical mode decomposition with adaptive noise,CEEMDAN)对风速序列进行分解,转化为一系列较为平稳的子模态,从而降低预测的复杂度;采用具有双向信息流结构的双向长短时记忆网络(bidirectional long short-term memory,BiLSTM)挖掘各分量的变化规律,同时注意力机制(attention mechanism,AM)为神经网络的隐藏层状态分配相应权重,突出长时间序列中的关键信息,并利用贝叶斯优化对模型超参数进行寻优;将各分量的预测结果进行叠加作为最终结果。通过实际算例对比分析可知,该模型在单步与多步预测任务中均展现出良好的预测性能。

关键词：超短期风速预测自适应噪声完备集合经验模态分解双向长短时记忆注意力机制贝叶斯优化

Hierarchically porous zeolites synthesized with carbon materials as templates

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Frontiers of Chemical Science and Engineering 2021年第6期15卷 1444-1461页

作者： Huan Wang Guo Du Jiaqing Jia Shaohua Chen zhipeng su Rui Chen Tiehong Chen Institute of New Catalytic Materials Science School of Materials Science and EngineeringKey Laboratory of Advanced Energy Materials Chemistry(MOE)Nankai UniversityTianjin300350China

Hierarchically porous zeolites are promising candidates in catalytic conversion of relatively bulky molecules,and their syntheses have attracted significant *** both industrial and scientific perspectives,different carbon materials have been widely employed as hard templates for the preparation of hierarchically porous zeolites during the past two *** this review,the progress in synthetic strategies using carbon materials as templates is comprehensively *** on the affinity between the carbon templates and zeolite precursors,the substantial strategies for synthesizing hierarchical zeolites are introduced in direct templates and indirect *** templates methods,by which the carbon materials are directly mixed with precursors gel as hard templates,are first ***,we discuss the indirect templates method(crystallization of carbon-silica composites),by which the carbon is produced by in situ pyrolysis of organic-inorganic *** addition,the technique of encapsulating metal species into zeolites crystals with the assistance of carbon templates is also *** the conclusion part,the factors affecting the synthesis of carbon-templated hierarchically porous zeolites are *** review is expected to attract interest in the synthesis strategies of hierarchically porous zeolites,especially cost-effective and large-scale production methodologies,which are essential to the industrial application of hierarchical zeolites.

关键词： hierarchical zeolites carbon materials direct templates indirect templates carbon-silica composites

The Long Noncoding RNA-H19 and Pituitary Adenomas

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The Long Noncoding RNA-H19 and Pituitary Adenomas

Customizable multifunctional metasurface absorber based on bidirectional deep neural networks covering the quasi-entire terahertz band

第十六届中国医师协会神经外科医师年会

作者： Zerui Wu zhipeng su Zhe Bao Wu Department of Neurosurgery First Affiliated Hospital of Wenzhou Medical University

Objective:To investigate the role of H19 on pituitary adenomas and its underlying mechanism in vitro and in vivo..Methods:Pituitary tumor tissues were obtained from pituitary tumor patients who underwent surgery between 2015 and 2020 at the Department of Neurosurgery,Ruijin Hospital of Shanghai Jiaotong University and Department of Neurosurgery,First Affiliated Hospital of Wenzhou Medical University;The Cell Counting Kit-8(CCK-8) assay was used to test cell viability;Real-time quantitative PCR was used to test the level of H19 and miR-93a;Western blot experiments were conducted to test the ATG7 expression level;Luciferase reporter assay and RNA immunoprecipitation were used to ensure the combination of H19 and miR-93a;Xenograft experiments were used to test the effect of H19 and miR-93a in ***:H19 inhibited tumor growth and had a synergistic effect with DA treatment on prolactinomas in vitro and in ***,H19 promoted ATG7 expression in pituitary tumor cells by inhibiting miR-93a *** addition,a potential binding site between miR-93 and H19 was confirmed,and low expression of miR-93 was previously found in DA-resistant ***,we showed that miR-93a regulates ATG7 expression by targeting ATG7 ***:Our study has identified the role of the H19-miR-93-ATG7 axis in tumor growth and DA treatment of pituitary tumors,which may be a potential therapeutic target for human pituitary tumors..

关键词： lncRNA H19 pituitary tumor miRNA-93 ATG7

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Chinese Optics Letters 2024年第6期22卷 182-190页

作者： zhipeng Ding Wei su Lipeng’an Ye Yuanhang Zhou Wenlong Li Riaz Ali Bin Tang Hongbing Yao College of Mechanics and Engineering Science Hohai UniversityNanjing 211100China School of Microelectronics and Control Engineering Changzhou UniversityChangzhou 213164China

In this work, we propose a novel approach that combines a bidirectional deep neural network(BDNN) with a multifunctional metasurface absorber(MMA) for inverse design, which can effectively address the challenge of on-demand customization for absorbers. The inverse design of absorption peak frequencies can be achieved from 0.5 to 10 terahertz(THz), covering the quasi-entire THz band. Based on this, the BDNN is extended to broadband absorption, and the inverse design yields an MMA at the desired frequency. This work provides a broadly applicable approach to the custom design of multifunctional devices that can facilitate the evaluation and design of metasurfaces in electromagnetic absorption.

关键词： terahertz inverse design bidirectional deep neural network metasurface