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UDT:U-shaped deformable transformer for subarachnoid haemorrhage image segmentation

CAAI Transactions on Intelligence Technology 2024年第3期9卷 756-768页

作者： Wei Xie Lianghao Jin Shiqi Hua Hao Sun Bo Sun zhigang tu Jun Liu Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning Central China Normal UniversityWuhanChina School of Computer Science Central China Normal UniversityWuhanChina National Language Resources Monitoring and Research Center for Network Media Central China Normal UniversityWuhanChina The First Affiliated Hospital of Dalian Medical University DalianChina State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhanChina Information Systems Technology and Design Pillar Singapore University of Technology and DesignSingaporeSingapore

Subarachnoid haemorrhage(SAH),mostly caused by the rupture of intracranial aneu-rysm,is a common disease with a high fatality *** lesions are generally diffusely distributed,showing a variety of scales with irregular *** complex characteristics of lesions make SAH segmentation a challenging *** cope with these difficulties,a u-shaped deformable transformer(UDT)is proposed for SAH ***,first,a multi-scale deformable attention(MSDA)module is exploited to model the diffuseness and scale-variant characteristics of SAH lesions,where the MSDA module can fuse features in different scales and adjust the attention field of each element dynamically to generate discriminative multi-scale ***,the cross deformable attention-based skip connection(CDASC)module is designed to model the irregular edge char-acteristic of SAH lesions,where the CDASC module can utilise the spatial details from encoder features to refine the spatial information of decoder ***,the MSDA and CDASC modules are embedded into the backbone Res-UNet to construct the proposed *** experiments are conducted on the self-built SAH-CT dataset and two public medical datasets(GlaS and MoNuSeg).Experimental results show that the presented UDT achieves the state-of-the-art performance.

关键词： image segmentation medical image processing

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安徽省城市工业遗址向公共文化空间改造探索

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黄山学院学报 2024年第4期26卷 102-106页

作者：赵蕾涂志钢马鞍山学院艺术设计学院安徽马鞍山243100 韩国国民大学技术设计研究生院韩国首尔02707

将安徽省城市工业遗址空间改造为公共文化空间,可促进安徽历史文化传承与保护,促进安徽城市功能多元化与再生,丰富安徽居民文化生活与社区互动。基于此,将场所认同理论导入城市工业遗址向公共文化空间改造的过程,从强化空间方向认同、... 详细信息

将安徽省城市工业遗址空间改造为公共文化空间,可促进安徽历史文化传承与保护,促进安徽城市功能多元化与再生,丰富安徽居民文化生活与社区互动。基于此,将场所认同理论导入城市工业遗址向公共文化空间改造的过程,从强化空间方向认同、促进空间文化认同和实现空间体验认同三个层面,通过视觉形态更新、场地功能置换、场所精神植入完成对合肥钢铁厂部分遗址空间向冶钢博物馆的设计实践,以期为安徽省工业遗址改造提出可借鉴的思路和方法。

关键词：城市工业遗址公共文化空间改造

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基于安全理念的高校实验室开放式管理体系研究

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无线互联科技 2024年第8期21卷 83-86页

作者：许雪屠志刚无锡学院江苏无锡214105

高校实验室是培育高质量人才的关键平台,其资源的科学有效管理直接影响着人才培养的效果。因此,提升实验室的开放度和保障其安全运作成为至关重要的基础条件。文章深入探讨了实验室安全管理的现状,针对如何安全地开放实验室提出了一系... 详细信息

高校实验室是培育高质量人才的关键平台,其资源的科学有效管理直接影响着人才培养的效果。因此,提升实验室的开放度和保障其安全运作成为至关重要的基础条件。文章深入探讨了实验室安全管理的现状,针对如何安全地开放实验室提出了一系列具体策略。文章构建了一个旨在增强师生安全意识和规范操作习惯的高校开放实验室安全管理系统框架,为高校实验室安全高效地开放提供新思路。

关键词：高校实验实验室管理开放理念

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Multi-scale attention encoder for street-to-aerial image geo-localization

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CAAI Transactions on Intelligence Technology 2023年第1期8卷 166-176页

作者： Songlian Li zhigang tu Yujin Chen Tan Yu State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhanChina Department of Informatics Technical University of MunichGarchingGermany Baidu USA SunnyvaleCaliforniaUSA

The goal of street-to-aerial cross-view image geo-localization is to determine the location of the query street-view image by retrieving the aerial-view image from the same *** drastic viewpoint and appearance gap between the aerial-view and the street-view images brings a huge challenge against this *** this paper,we propose a novel multiscale attention encoder to capture the multiscale contextual information of the aerial/street-view *** bridge the domain gap between these two view images,we first use an inverse polar transform to make the street-view images approximately aligned with the aerial-view ***,the explored multiscale attention encoder is applied to convert the image into feature representation with the guidance of the learnt multiscale ***,we propose a novel global mining strategy to enable the network to pay more attention to hard negative *** on standard benchmark datasets show that our approach obtains 81.39%top-1 recall rate on the CVUSA dataset and 71.52%on the CVACT dataset,achieving the state-of-the-art performance and outperforming most of the existing methods significantly.

关键词： global mining strategy image geo-localization multiscale attention encoder street-to-aerial cross-view

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低摩擦因数热收缩BOPP包装薄膜的开发

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中国塑料 2024年第6期38卷 78-81页

作者：谢波涂志刚周先进张尚先熊立贵杨亭广东开放大学/广东理工职业学院广州510091 湛江包装材料企业有限公司广东湛江524022

研究了一种高性能BOPP薄膜的开发,采用特殊的原料配方和加工工艺制备。通过与标准型BOPP薄膜对比,跟踪30天内第1天、第7天、第15天、第30天的摩擦因数、热收缩率、光学性能,分析数据得出新开发薄膜的各性能都有所优化。该BOPP薄膜具有... 详细信息

研究了一种高性能BOPP薄膜的开发,采用特殊的原料配方和加工工艺制备。通过与标准型BOPP薄膜对比,跟踪30天内第1天、第7天、第15天、第30天的摩擦因数、热收缩率、光学性能,分析数据得出新开发薄膜的各性能都有所优化。该BOPP薄膜具有低摩擦因数、高热收缩性能和良好的光学性能。

关键词：双向拉伸聚丙烯薄膜摩擦因数光学性能热收缩

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钱江源⁃百山祖国家公园钱江源片区生态产品价值实现路径

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国家公园（中英文） 2024年第5期2卷 342-350页

作者：张璇高睿涓涂志刚李健浙江农林大学风景园林与建筑学院杭州311300 浙江省新型重点专业智库——浙江农林大学生态文明研究院杭州311300

国家公园生态产品价值实现对我国自然保护地的生态产品价值实现具有重要的引领示范作用。以钱江源⁃百山祖国家公园之钱江源片区为例,凭借其丰富的自然资源和独特的生态环境优势,在探索和实现生态产品价值方面具有显著的潜力,通过分析钱... 详细信息

国家公园生态产品价值实现对我国自然保护地的生态产品价值实现具有重要的引领示范作用。以钱江源⁃百山祖国家公园之钱江源片区为例,凭借其丰富的自然资源和独特的生态环境优势,在探索和实现生态产品价值方面具有显著的潜力,通过分析钱江源片区在生态产品价值实现上的一系列成效,从生态产品构成视角探索钱江源片区优质生态产品的价值实现路径。研究表明:钱江源片区虽然取得地役权改革、品牌增值、自然教育等多项研究成就,但仍然面临着生产经营与生态保护等问题;通过提出生态调节产品、物质供给产品和人文服务产品的价值实现路径,为钱江源片区生态产品市场化发展提供了切实可行的建议,以期对钱江源⁃百山祖国家公园钱江源片区生态产品市场化管理提供科学支撑。

关键词：生态产品价值实现钱江源⁃百山祖国家公园钱江源片区现实困境路径探讨

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The landscape of UBE2S in hepatocellular carcinoma: Prognostic significance, immuno-oncology feature and drug response

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Genes & Diseases 2023年第2期10卷 363-365页

作者： Lipeng Qiu Yue Wang Zhihuan Li zhigang tu Hanqing Liu School of Life Sciences Jiangsu UniversityZhenjiangJiangsu 212013China School of Pharmacy Jiangsu UniversityZhenjiangJiangsu 212013China

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide.1 E2 ubiquitin conjugating enzymes (UBE2) are potential therapeutic targets in tumors arising from genomic instability and tumor microenvironment (TME).2,3 UBE2S, an important UBE2, has demonstrated strong oncogenic activities in various malignant cancers, including HCC. However, a comprehensive study regarding its role in HCC is still absent, and its association with immunology and drug response of HCC is still unclear. In this study, we conducted a pan-cancer analysis of UBE2S expression and prognosis, carried out enrichment analysis of UBE2S-associated genes, and analyzed association between UBE2S expression and HCC microenvironment, stemness and drug response. Collectively, our results demonstrated that UBE2S expression was significantly increased in multiple types of cancer, including HCC, and harbors prognostic values for HCC. Potential function of UBE2S involves modulation of ubiquitin mediated proteolysis and cell cycle progression. Furthermore, in HCC, UBE2S expression was positively correlated with TME infiltration, microsatellite instability (MSI), DNA methylation, stemness and drug response. These findings highlighted the possible pivotal roles of UBE2S in HCC prognosis, precision immunotherapy and drug response.

关键词： drug prognosis cancer

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Assessment of internal controls for data normalization of gene expression after different bacterial stimulation by quantitative real-time PCR in golden pompano Trachinotus blochii

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Journal of Oceanology and Limnology 2020年第2期38卷 480-489页

作者： CHEN Xiaojuan ZHANG Xiaoqi SUN Yun tu zhigang CAO Zhenjie WANG Shifeng ZHOU Yongcan State Key Laboratory of Marine Resource Utilization in South China Sea Hainan UniversityHaikou 570228China Hainan Academy of Ocean and Fisheries Sciences Haikou 570228China

Trachinotus blochii is one of the important commercial fish *** this study,we aim to confirm the reliability reference genes in *** during different bacterial challenge through quantitative real-time PCR(qRT-PCR).The expression of the seven selected genes in four immune organs(i.e.,spleen,kidney,intestine,and gill)stimulated with Vibrio harveyi,Edwardsiella tarda,and Streptococcus agalactiae were determined by *** PCR data was analyzed using the geNorm and NormFinder *** results showed the selection of the internal controls should be tissue specific when studying gene expression in response to bacterial *** 48 h of stimulation with ***,geNorm ranked EF1 A/Actin,18 S rRNA/B2M,UBCE/B2M,and 18 S rRNA/B2M,as the most stably expressed genes in spleen,kidney,intestine,and gill,*** 48 h of stimulation with ***,geNorm ranked 18 S rRNA/EF1 A,18 S rRNA/B2M,B2M/RPL13,and 18 S rRNA/EF1 A,as the most stably expressed genes in spleen,kidney,intestine,and gill,*** 48 h of stimulation with ***,18 S rRNA/EF1 A,18 S rRNA/B2 M,B2 M/Actin,and 18 S rRNA/B2M were ranked as the most stably expressed genes in spleen,kidney,intestine,and gill,*** to the results analyzed by geNorm,reference genes received similar rankings when using NormFinder *** results showed that the reference genes appeared to be not only tissue specific,but also specific to the infecting species of *** one gene is preferred when *** were infected by bacteria,18 S rRNA,B2M,B2M,18 S rRNA may be used in spleen,kidney,intestine,and gill,respectively.

关键词： Trachinotus blochii housekeeping gene expression stability reference gene

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Transient HSP90 inhibition enhances the sensitivity of mantle cell lymphoma to poly(ADP-ribose)polymerase(PARP)inhibitors

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Genes & Diseases 2023年第5期10卷 1791-1794页

作者： Chaowen Shi Dewan Ren Yufeng Gao Ya-Mei Dang zhigang tu Hanqing Liu School of Life Sciences Jiangsu UniversityZhenjiangJiangsu 212013China School of Pharmacy Jiangsu UniversityZhenjiangJiangsu 212013China Department of Pathology Gansu Provincial HospitalLanzhouGansu 730000China

Mantle cell lymphoma(MCL)is an aggressive subtype of non-Hodgkin lymphoma(NHL)characterized by the overexpression of cyclin D1 and deregulated cell cycle.1 Ganetespib(STA-9090),a second-generation HSP90 inhibitor,dramatically disrupted oncogenic cellular processes resulting in the inhibition of client protein-derived tumors in preclinical studies.2 The synthetic lethal strategy using poly(ADP-ribose)polymerase(PARP)inhibitors(PARPis)has been reported as a powerful therapeutic intervention in MCL and their effectiveness can be increased by a deficiency in DNA damage repair(DDR),especially homologous recombination deficiency.3 Since we found earlier that transient ganetespib treatment can induce defects in DDR,we hypothesized that ganetespib treatment can possibly enhance the sensitivity of MCL cells to PARPis and HSP90 and PARP is can be demonstrated as promising combination therapies for MCL.

关键词： lymphoma PARP sized

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A spatial attentive and temporal dilated(SATD)GCN for skeleton-based action recognition

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CAAI Transactions on Intelligence Technology 2022年第1期7卷 46-55页

作者： Jiaxu Zhang Gaoxiang Ye zhigang tu Yongtao Qin Qianqing Qin Jinlu Zhang Jun Liu State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhanChina State Grid Wuhan Power Supply Company WuhanChina Shenzhen Infinova Ltd.Company ShenzhenChina Information Systems Technology and Design Pillar Singapore University of Technology and DesignSingapore

Current studies have shown that the spatial-temporal graph convolutional network(STGCN)is effective for skeleton-based action ***,for the existing STGCN-based methods,their temporal kernel size is usually fixed over all layers,which makes them cannot fully exploit the temporal dependency between discontinuous frames and different sequence ***,most of these methods use average pooling to obtain global graph feature from vertex features,resulting in losing much fine-grained information for action *** address these issues,in this work,the authors propose a novel spatial attentive and temporal dilated graph convolutional network(SATD-GCN).It contains two important components,that is,a spatial attention pooling module(SAP)and a temporal dilated graph convolution module(TDGC).Specifically,the SAP module can select the human body joints which are beneficial for action recognition by a self-attention mechanism and alleviates the influence of data redundancy and *** TDGC module can effectively extract the temporal features at different time scales,which is useful to improve the temporal perception field and enhance the robustness of the model to different motion speed and sequence ***,both the SAP module and the TDGC module can be easily integrated into the ST-GCN-based models,and significantly improve their *** experiments on two large-scale benchmark datasets,that is,Ntu-RGB+D and Kinetics-Skeleton,demonstrate that the authors’method achieves the state-of-the-art performance for skeleton-based action recognition.

关键词： classification. skeleton action

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